Peptidases • Lentinula edodes W1-26 v1.0
Annotations/GenomesLenafn1Lenafn_TMI1502_1Lened_B_1_1Lenedo1Lenlat1Lennov1Lenra_T_1Lenrap1Lenrap1_155Lentinedodes1LraINPA1820_1TotalAnnotation Description
Merops
3493373573343313303483453583073553,751
3435303031293727422735357Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
3343333332333Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1516161916181817151217179Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6555564455555Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
253113332629Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
998998121313810108Water nucleophile; water bound by Gln and Glu; all endopeptidases
99481099896990Families of peptidase inhibitors not assigned to clans
12111118
111111111110
4344443444543
2222222221221Families of metallopeptidases not assigned to clans
1212151411131011101010128Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1171111111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111111111Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
109971010101011810104Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1514171515151515161316166Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1414221615161416141615172Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
311211110Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
8788675567572Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
2725302726262528262527292Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6745456655760Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
1312131112121516141015143Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1251171221171211151261261281191281,344Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3323331223227Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3322223323328Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111111211112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
4434444444443Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111111111
1614181514131515161214162
112