Peptidases • Tremellomycetes
Annotations/GenomesCrycu1Cryne_H99_1Cryne_JEC21_1Cryte1Cryvi1Crywi1Diocr1Felpe1Fibin1Kocim1Mrafri1Papla1Sirint1Treen1Treme1Trias2479Trias8904Trich1Trigue1Triol1TotalAnnotation Description
Merops
2161571552311711812832171812072091701962331491971942033022154,067
176686810869646751413133814204Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
3111442132122114315345Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
1414112115133315121714181614141413121515310Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4333217454355342256475Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121123111114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
122111111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Water nucleophile; water bound by Gln and Glu; all endopeptidases
2223224222222223321244Families of peptidase inhibitors not assigned to clans
112
3339
11
11
3221124311312111132338
112122222412221124135Families of metallopeptidases not assigned to clans
98107181017871315799911811119206Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111121111111111111120Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1121111111111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
213211212Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
88887712878107888679128164Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
12131012121010181012189132091012121812252Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
15101115813151613129101920101111151515263Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
55555575556555534555100Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
111111118Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1111111111111Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2217182020223222212220192525202223212722440Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3323325232744433448372Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1112218Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1112212114311111111128Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
54404483365473655253574748713153535185551,105Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111023168695528110872011142Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3323334334433432133360Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111121121211111111123Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3333244342235242122458Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111111111120
14101010128151211111310121191011131113226
11
1111116