Peptidases • Peniophora sp. CONTA v1.0
Annotations/GenomesAurvu1Clapy1Fomme1Hetan1Lopni1Ricme1Stehi1TotalAnnotation Description
Merops
3883723164184404142,348
563733425136255Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1112128Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
161221252424122Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
87515101055Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1134110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
8477632Water nucleophile; water bound by Gln and Glu; all endopeptidases
23333317Families of peptidase inhibitors not assigned to clans
11
112
1111127
77245833
22211715Families of metallopeptidases not assigned to clans
22181315191299Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
771112111462Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
141613222527117Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
99813131567Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1211117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
75765636Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
252020212421131Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
877811546Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Serine or threonine nucleophile; N-terminal nucleophile
36328181719130Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
121146116157162146848Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
271771034Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
44434322Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
35323420Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
191431222323132
112
224