Peptidases • Gigaspora rosea v1.0
Annotations/GenomesGigro1Gloin1Lacbi2Morel2Mucci2Phybl2Rhice1_1Rhidi1Rhiir2_1RhiirA1_1RhiirA4RhiirA5RhiirB3RhiirC2Rhimi1_1Tubme1TotalAnnotation Description
Merops
4933073384053042842302672733312772932852802531664,786
851232362428768121191111203315Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
242544221111214238Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
52312925352927302929313028272918479Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
649767344434436276Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
331323255544442151Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
12112222222221125Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4511876554756557494Families of peptidase inhibitors not assigned to clans
112
1818
213
1113
11
11
112
1211111111112116
221211211
11
11
113111111111111118Families of metallopeptidases not assigned to clans
1920172823171314152315232120188294Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
14117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
2542413232231135Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
27434334556454463Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
671210131256776666148131Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
101216131115912151813131414118204Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
78971296679668866120Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11112111111111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
349365444444446472Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
22Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11Asparagine nucleophile; all self-processing endopeptidases
741231131011119116711161Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24272320231718192025202623211717340Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3612633654944443480Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
152213324326Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11111117Serine or threonine nucleophile; N-terminal nucleophile
1117101910191321192121191722115255Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1237874956755647478847682827546411,194Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
822181222823221156Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
874554444744446276Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111133122222221127Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
536477544343246269Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111119Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111111116
16172170242614171215151614152411327
11
11
11111111122114
11
448