Peptidases • Ascoidea rubescens NRRL Y17699 v1.0
Annotations/GenomesAscru1Babin1Canar1Canca1Canta1Cybja1Hanpo2Hanva1_1Hypbu1Lipst1_1Metbi1Nadfu1Pacta1_2Picme2Saico1Wican1TotalAnnotation Description
Merops
1551711411481491671511111532001421591521342151822,530
101212415145610101261061212156Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11121111111719Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
14171216131614111522141613132618250Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
942122334223223448Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211121211114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Water nucleophile; water bound by Gln and Glu; all endopeptidases
443244423345425457Families of peptidase inhibitors not assigned to clans
112
11114
1111121111112
222223232322221436
11111111121112117Families of metallopeptidases not assigned to clans
91389666611106776106126Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111112116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12221123121513128Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
22Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6768778667776866108Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8141013121913111210111514111319205Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
546337924544976684Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
32444533434453354Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19161620181818161819162018192219292Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2323332423235340Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
733635344634431463Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
31453029333233213560292429245244551Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111311211214Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
433333333334334351Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111126Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
333213212525424446Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
224Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111115
8761099979131114981510154
112
112113211
22
111216