Peptidases • Dissoconium aciculare v1.0
Annotations/GenomesAltbr1CocheC5_3Disac1Dotse1Hyspu1Mycgr3Sepmu1TotalAnnotation Description
Merops
2823722613193422861,862
122910172210100Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
712244534Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192826252725150Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34332318Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11332313Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
25435221Water nucleophile; water bound by Gln and Glu; all endopeptidases
45435425Families of peptidase inhibitors not assigned to clans
2111117
53353322
26422117Families of metallopeptidases not assigned to clans
131189281887Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
8734325Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6668101046Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
162616171719111Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1296106952Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33344320Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
423211Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212021242121128Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
109736237Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
3111118Serine or threonine nucleophile; N-terminal nucleophile
916910161171Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
871329112411997650Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
65678638Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333318Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22223314Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
23253419Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
123Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
1515121491176
11
11
3322111