Peptidases • Triparticalcar arcticum BR59 v1.0
Annotations/GenomesBlyhe1Chylag1Chytri1Gaesem1Obemuc1Rhihy1Spipu1Triarc1TotalAnnotation Description
Merops
2563123552073303602102172,247
4010274152788139Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1253332221Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1620271520221518153Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
26641063542Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
5432342225Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
26648114445Families of peptidase inhibitors not assigned to clans
22
11
11
11
11
31112210
1225
1113
12111118Families of metallopeptidases not assigned to clans
1546352246251115215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2733562331Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
212211110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1244554328Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
579881191067Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
11132592725129131Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
281141295556Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
21111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3544654637Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11215Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
213113112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1921271720191919161Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4473695442Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1112117Serine or threonine nucleophile; N-terminal nucleophile
152948581021100Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
71671004180984935541Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1065312131252Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5576557747Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2231222115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3237454432Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
1629232115311518168
112