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Peptidases • Pseudographis elatina
Annotations/GenomesAmore1Botci1Chalo1Melbi2Melva1Oidma1Pseel1Sclsc1TotalAnnotation Description
Merops
2563246724956526223132773,611
1518502743362312224Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
74161313113673Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2021293540331418210Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4255543230Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
113211110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
131311111Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2318615137266Water nucleophile; water bound by Gln and Glu; all endopeptidases
5545454537Families of peptidase inhibitors not assigned to clans
11
11125
22
2211211111
3473863337
4487784345Families of metallopeptidases not assigned to clans
9923172215148117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1311111312Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1422211215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
88101010109873Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1820382732301917201Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11823182218108118Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
4444444432Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
34442219Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2222272428292125198Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
261151183450Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2121219Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1312352534381812187Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
751312901842862741171001,457Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
462122192664108Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333332222Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1122131112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
3156523328Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1212142315241217129
11114
216445426