Peptidases • Apiospora montagnei NRRL 25634 v1.0
Annotations/GenomesApimo1Chagl_1Crypa2Maggr1Neucr1Neudi1Neute_matA2Neute_mat_a1Spoth2Thite2TotalAnnotation Description
Merops
4652663773372042152192432562,582
281527181816161726181Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
134Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
62124331325Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
241429151413132015157Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
32433333327Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2221111111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
41111111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
24812222427Water nucleophile; water bound by Gln and Glu; all endopeptidases
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
44343443534Families of peptidase inhibitors not assigned to clans
11
11
21122212215
61162221425
11
53331116Families of metallopeptidases not assigned to clans
23913239101069112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
43142223223Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2222222115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
961086668867Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
281622191113131511148Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1961568998989Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
22Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
33333444431Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
43119Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
222124211819192020184Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
57343234334Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
2215Serine or threonine nucleophile; N-terminal nucleophile
123Families of serine peptidases not assigned to clans
30122020688119124Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1861071371206268698086915Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
115831557752Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43334223327Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11211111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
32432223223Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1179Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
111415111212141314116
11
11
413811119