Peptidases • Coniella lustricola B22-T-1 v1.0
Annotations/GenomesAciaci1Calpu1Chagl_1ConPMI546Conli1Conlig1Crypa2Diaam1Gaegr1Grocl1Lolmi1Maggr1Magpo1Melsp1Myche1Neucr2Neucr_trp3_1Neudi1Neute_matA2Neute_mat_a1Ophpi1Ophpic1Phaal1Pilidi1Podan2Podcur1Spoth2Thian1Thiap1Thiar1Thihy1Thite2ThoPMI491_1TotalAnnotation Description
Merops
30831826634232937337741933423932533727548822224221920421521920924435831529535824319025626923125698810,263
182015252225271813112118172316191618161614152021212617171816142667666Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11111113111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
132466161332261544332241221223238100Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1113Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
181614151715292418162515162217161414131315142427181620161616151541600Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
222444463343353333333443343353336114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211122212231111111211111111137Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111111111111111111111111111233Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
212121110Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111111111111111111124Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
6444348625411732222211474522534418132Water nucleophile; water bound by Gln and Glu; all endopeptidases
11111111111111418Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
454444364344244333443344333443555125Families of peptidase inhibitors not assigned to clans
11
11
11
2111117
11
111212122122123222112122222222253
44184416514636111222244441155449113
11215
22323236422317122131421132311180Families of metallopeptidases not assigned to clans
1412912172013171991423112261210910108719101422610101012939445Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
133221651244432222213143323332382Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112221211221212222232222212421256Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1086969109571083108107666699107788878813261Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
192516161821222721182119243015141511131315182315191915121516121150618Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1724681113151871112672071098998112113101489797950403Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11112219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1111116Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
323333333333233443445332434333342104Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111111111411219Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
21234133111111111138Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
232121232628242423192321172421232018191922222523222320222121192033730Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3277773573445832232333733642746314152Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111117Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
2111122221221111326Serine or threonine nucleophile; N-terminal nucleophile
1122118Families of serine peptidases not assigned to clans
111612222125202319161720173298968871425141619116121410967543Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
110115107126114135137153109741021208619372716562686956801061131041398048739063864433,569Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
5757810896583585551555576687492734220Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
32332333334334322422332333333333395Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2111112111112111111111211111111136Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1211112122317Serine nucleophile; catalytic residues in the order Ser, Glu, His
33243544322333344222432332312232495Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
42111115117411121136Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111121111111111111111134
109141298151114913119181013111212141510151010131391513171415403
11211118
11
112
12133337934887111113145333213104