Peptidases • Verruculina enalia CBS 304.66 v1.0
Annotations/GenomesAmnli1Karrh1Lenfl1Melpu1Plesi1Spofi1Trepe1Veren1TotalAnnotation Description
Merops
3774224284663532504163553,067
2417212012162218150Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
7865747751Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2932313132212829233Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5465435436Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1121121110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2332222117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124411115Water nucleophile; water bound by Gln and Glu; all endopeptidases
5545545538Families of peptidase inhibitors not assigned to clans
112
111111118
6764436642
5888435546Families of metallopeptidases not assigned to clans
1417162720101814136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
6564453437Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2211122112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
7857766854Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2629263326192518202Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
109131212714986Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3333333324Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
3443212221Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2123212221192021168Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
611107568760Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
221117Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11111117Serine or threonine nucleophile; N-terminal nucleophile
131913221681112114Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
140160172177127771701371,160Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
81617257414798Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5332323324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111121210Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
4444545434Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
141415209111617116
112
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