Peptidases • Exophiala alcalophila J33 v1.0
Annotations/GenomesAspni7Exoalc1Exoalc1_J33Gymci1_1Monpu1Phach1TotalAnnotation Description
Merops
3883823772192432331,842
15119981264Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
8111034339Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
342526253322165Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33323216Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111126Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
512311Water nucleophile; water bound by Gln and Glu; all endopeptidases
55545327Families of peptidase inhibitors not assigned to clans
11
11
1111217
46622222
73262323Families of metallopeptidases not assigned to clans
14131212101172Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111126Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
87767843Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
262119131917115Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
17292971020112Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
53333320Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202828202016132Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
83435225Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11125Serine or threonine nucleophile; N-terminal nucleophile
123349738Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
160171170676569702Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
10131348351Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3223313Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22222212Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
13321111Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
33Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
9910891055
11
3233213