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Peptidases • Acremonium alcalophilum v2.0
Annotations/GenomesAcral1_c3aAcral2Chagl_1Necha2Spoth2Thite2Triat1Trire2TriviGv29_8_2TotalAnnotation Description
Merops
1962665472432562864522,246
8152017261522123Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1236Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
129133423Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
16142220152122130Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
323333320Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11211129Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
43246726Water nucleophile; water bound by Gln and Glu; all endopeptidases
543355429Families of peptidase inhibitors not assigned to clans
21222211
212141112
235111417Families of metallopeptidases not assigned to clans
1192069111581Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
435323323Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2211118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
76138881060Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16163515111824135Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
862889131890Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
334444426Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
5128Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21212620202327158Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2714434842Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
124613Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
712191191429101Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
48107239808692183835Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
15317761471Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333332320Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
323323319Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
213Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
12141313141523104
11
172212