Peptidases • Postia placenta MAD-698-R-SB12 v1.0
Annotations/GenomesAntsi1Cersu1Daequ1Fompi3Laesu1Phchr2PosplRSB12_1Wolco1TotalAnnotation Description
Merops
3053403193383333543343212,644
3641533939624740357Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2124222116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1813131412161316115Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
579102236870Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111227Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
136611128Water nucleophile; water bound by Gln and Glu; all endopeptidases
1222252218Families of peptidase inhibitors not assigned to clans
11
11
111111118
33114113
4243735432Families of metallopeptidases not assigned to clans
1091011139141187Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
121111119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111111310Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1113Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
109778910969Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1413131613151317114Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
121110111310111290Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5655967649Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2317222223222024173Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
7644465541Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2224212814122320164Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
97136109116114127113105917Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3236134123Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4333225426Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3354544331Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1621101616141722132
112
1113
112