Peptidases • Sugiyamaella americana NRRL YB-2067 v1.0
Annotations/GenomesArxad1Nadfu1Sacce1Sugame1Symat1Tripe1Yarli1Zyghe1_2TotalAnnotation Description
Merops
2061591372002081902121841,496
21681924193514146Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
111221210Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2116151220171418133Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2323332220Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
122117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3524643330Families of peptidase inhibitors not assigned to clans
1113
11
212122212
2233222218
1122118Families of metallopeptidases not assigned to clans
1077131112101383Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2512132117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
8756977756Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171591414131319114Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
4444544736Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4425554332Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2120202018192017155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5383234432Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1111217Serine or threonine nucleophile; N-terminal nucleophile
44345414442Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5124255448464437329Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2215Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3433333325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
2524642631Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
13149121313131299
112
1113