Peptidases • Pycnoporus puniceus CIRM-BRFM 1868 v1.0
Annotations/GenomesPycci1Pycco1Pycco1662_1Pycpun1Pycsa1TotalAnnotation Description
Merops
3173673643013761,725
4654493754240Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2222210Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
111412111159Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5335420Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
123Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1223210Water nucleophile; water bound by Gln and Glu; all endopeptidases
2222210Families of peptidase inhibitors not assigned to clans
112
2222210
2222210Families of metallopeptidases not assigned to clans
141618141880Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11125Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11101081150Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171417171479Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12111191154Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5666629Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1822222322107Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4555524Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2527261829125Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
117147144106145659Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
5344420Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3332516Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2334416Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
91213131461
11
112