Peptidases • Melampsora allii-populina 12AY07 v1.0
Annotations/GenomesAgahy1Croqu1Hetpy1Melap1finSC_191Melli1Mellp2_3Mixos1Pucgr1Pucst1Puctr1Rhosp1Schco3Trisp1TotalAnnotation Description
Merops
1781921722611782311832242081653451742,511
1127122739263014149297245Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
21111112322118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201922341424112219152017237Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
32373223325237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121221211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
33242322322331Families of peptidase inhibitors not assigned to clans
112
11
111126
22263613827143
111111113112Families of metallopeptidases not assigned to clans
10568109711872216119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
212229Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1112319Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111112211214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
667647476710575Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
87884961499235110Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5565545961012577Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
65477645555564Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
192318211717172622172217236Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
31241232327131Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
27395881612161390Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4654448843776052564213243737Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
22143517Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333322633438Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1112112121215Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3221114134224Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1211131291591818141211154
22
134