Peptidases • Tremellomycetes
Annotations/GenomesCrycu1Cryne_H99_1Cryne_JEC21_1Cryte1Cryvi1Crywi1Diocr1Felpe1Fibin1Filflo1Kocim1Mrafri1Nagvi1Papla1Sirint1Treen1Treme1Trias2479Trias8904Trich1Trigue1Triol1XandeAX4_1XandeCB38_1TotalAnnotation Description
Merops
2161571552311711812832171811782072091651701962331491971942033022151531524,715
17668681086129654675141313381465232Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
31114421322122211431531151Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
141411211513331512141714151816141414131215151414367Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
43332174524325534225642283Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211231111115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1221111111113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Water nucleophile; water bound by Gln and Glu; all endopeptidases
22232242222222222332122252Families of peptidase inhibitors not assigned to clans
112
3339
11
11
32211243111311211113232244
1121222222411222112413344Families of metallopeptidases not assigned to clans
98107181017871213151979991181111988253Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111211111111111111111124Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112111111211111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
213211212Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
888877128768107788867912867190Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
121310121210101810912181291320910121218121313299Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
151011158131516139129810192010111115151577294Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111111111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
555555755656555553455555121Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11111111111213Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111111111111113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
221718202022322221192220201925252022232127221718514Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
33233252352734443344834488Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1112218Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
11122121114321111111112134Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5440448336547365524753573447487131535351855538371,261Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11102316866952528110872011150Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33233343334433343213333372Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111211211211111111112229Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
33332443422233524212242166Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111111111111124
1410101012815121111111312101211910111311131010269
11
11111117