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Peptidases • Chalciporus piperatus 201810 CP v1.0
Annotations/GenomesBolcoc1Boled5Boledp1Chapip1Gyrli1Melbro1Paxru2Xerba1TotalAnnotation Description
Merops
2654314232994213302723392,780
25535447180303846473Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2112222113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2324231413161218143Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
71093764955Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112318Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
357533169132Water nucleophile; water bound by Gln and Glu; all endopeptidases
419162522454Families of peptidase inhibitors not assigned to clans
11
2421212418
2222222216Families of metallopeptidases not assigned to clans
1530242014131214142Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
33211111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
22Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
91112128118980Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2121171716161819145Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1014149111091491Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
122117Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
56510585549Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1111124112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2221191919342122177Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5444433734Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2171310886670Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
679410887761047190697Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
24517221Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3454333530Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4553342430Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111118
2619222234333843237
11
112