Peptidases • Chionosphaera apobasidialis 52639 v1.0
Annotations/GenomesAgahy1Atrsp2Chiap1Croqu1Hetpy1Mellp1Mixos1Naifl1Pucgr1Pucst1Rhoba1_1Rhomi1Rhosp1Spoli1Sporo1Trisp1TotalAnnotation Description
Merops
1784251971921721833032241851871652141581742,957
11331927123035141014925117257Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2411112223232127Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2024181922112122201315241617262Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3732324323222240Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11421211114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111111313Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3233222232233335Families of peptidase inhibitors not assigned to clans
1113
112
11114
21032213331251139
11
13111111111114Families of metallopeptidases not assigned to clans
102595671211109781016145Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211111121213Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1511311Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11111212111114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
61466746776767594Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
82710786121411139995148Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5146565491081048599Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
6855447575535574Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1925172318172126182017211817277Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
31121238222253147Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
31116Serine or threonine nucleophile; N-terminal nucleophile
29473841161212213111Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
46154535444609052475642613343835Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2612132431530Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3633324253334448Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
211122121215Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3442242144332240Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111113
122014111391218111214141411185
11
22
11
12339