Peptidases • Eremomyces bilateralis CBS 781.70 v1.0
Annotations/GenomesAplpr1Erebi1Leppa1Patat1Phycit1Sacpr1Totfu1Tryvi1TotalAnnotation Description
Merops
2942703482592552903883562,460
2512171115292619154Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
5352365332Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
2223292522262826201Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2352232423Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2223222116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1211117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3112231417Water nucleophile; water bound by Gln and Glu; all endopeptidases
5455545538Families of peptidase inhibitors not assigned to clans
11
11
1111122110
146617
53732311034Families of metallopeptidases not assigned to clans
91214171282212106Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2243113218Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2242222117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
5786666852Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2020201718212415155Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
108148101091281Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3433333325Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
2123112214Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2417202320212324172Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3452434328Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111211119Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1091567122226107Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9995110788798152138857Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
96823313650Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4333331323Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222221114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4335433328Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
111630141091111112
11
1331325321