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Peptidases • Phaeosphaeriaceae sp. PMI_808 v1.0
Annotations/GenomesAltbr1Ampqui1CocheC5_3Didex1Lepmu1PhaPMI808Pyrtr1Settu1Stano2TotalAnnotation Description
Merops
2823043723312604082973243432,921
122529231023131613164Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
741274889766Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
192428282231262225225Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34445444335Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12111211212Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2512213117Water nucleophile; water bound by Gln and Glu; all endopeptidases
45554555442Families of peptidase inhibitors not assigned to clans
21112121112
54335434536
25643625437Families of metallopeptidases not assigned to clans
131611141124141216131Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
87776777763Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111121110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
65676766756Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
162526252126192222202Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1289101316121311104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33343333328Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
44223223325Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212020202224192121188Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1059751089871Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
311111210Serine or threonine nucleophile; N-terminal nucleophile
9121691012131512108Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
879613211680147971141331,002Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
655821262753Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
32323323324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22212222217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
24353434533Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
15101511816111210108
11
31222111