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Peptidases • Golovinomyces orontii MGH1 v4.0
Annotations/GenomesAcema1Ascsa1Blugr1Cadsp1Golci1Golor4Leptod1Lorju1Lorma1Marbr1Phisc1TotalAnnotation Description
Merops
5622941457251542956574124142466484,552
34156317183335321041262Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1452172317910817104Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2919163717353421242326281Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4333364443441Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2111124531223Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2511121316Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1124Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111311111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
74145532839Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
4435565554551Families of peptidase inhibitors not assigned to clans
112
213
1211222213
63714543538
112
751102410662760Families of metallopeptidases not assigned to clans
1697337152815141621181Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1122112111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1221241112118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
108511410109941292Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
34165416114027261841265Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
191222524231011926143Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4444463443444Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
211725223328Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2421162720402526252126271Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
633132413633662Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
42111110Serine or threonine nucleophile; N-terminal nucleophile
351744013104222261234255Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238110393153567283147157692951,755Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1853026159223128Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333363332335Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2121121111114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2215Serine nucleophile; catalytic residues in the order Ser, Glu, His
6223253344236Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111121111112
1815143012281713141115187
2226
5141533628