Peptidases • Rhodocollybia butyracea AH 40177 v1.0
Annotations/GenomesGyman1Gymlu1Marfi1Monpe1_1Ompol1Rhobut1_1TotalAnnotation Description
Merops
6155614554572514612,800
565525192029204Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
23311212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
302324201821136Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
8116662764Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
8513623Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
10121831Water nucleophile; water bound by Gln and Glu; all endopeptidases
6121071743Families of peptidase inhibitors not assigned to clans
11
11
11
111115
86543733
3335519Families of metallopeptidases not assigned to clans
171240411413137Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
4129218Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
72221519Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1310111281569Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
272225301522141Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1415151881686Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
261312Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
75634631Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
252326221725138Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
111271061056Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
443011121230139Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238190202185951581,068Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
144551736Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
24331417Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
54314320Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
488713281324213
11