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Peptidases • Tolypocladium inflatum NRRL 8044
Annotations/GenomesAcrst1Beaba1Cloro1Cormi1Metac1Myrin1Tolinf1Trias1Triasp1Triat2Trici4Trihar1Trire2TotalAnnotation Description
Merops
4813657023213304392863603814002974762865,124
17221624201720192020152215247Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
13116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
9210333134723353Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19222318171717181820202021250Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
342433333335342Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111111111112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111211111211115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1741061288968676Water nucleophile; water bound by Gln and Glu; all endopeptidases
435233333454547Families of peptidase inhibitors not assigned to clans
11
11
112
11
212211221115
12112211111115
2327
328358422113143Families of metallopeptidases not assigned to clans
22263819152120141621142011257Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
143123414233333370Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22112211111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1071311910987108108120Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
36205020153517232424182418324Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
27143612161814131416141913226Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
444444344444451Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111211111111Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; all self-processing endopeptidases
51222710211112165Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23212622212420232325232223296Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
75124685585311483Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
243433233356445Serine or threonine nucleophile; N-terminal nucleophile
112Families of serine peptidases not assigned to clans
22324327342618262831172814346Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
21110430481871768713714014096210921,865Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
10162215177131414157176173Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
334333233333238Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111111111113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
332313333333336Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111113
91215813158131918151715177
1214
2310142122223236