PFAM Domains • Phytophthora ramorum v1.1
| Annotations/Genomes | Total | Annotation Description | ||
|---|---|---|---|---|
 PFAMs | 9,385 | 10,573 | 19,958 | |
| 1 | 1 | 7 transmembrane receptor (Secretin family) | ||
| 4 | 4 | 8 | 7 transmembrane sweet-taste receptor of 3 GCPR | |
| 49 | 54 | 103 | ATPase family associated with various cellular activities (AAA) | |
| 158 | 163 | 321 | ABC transporter | |
| 4 | 5 | 9 | ATP synthase alpha/beta family, nucleotide-binding domain | |
| 2 | 5 | 7 | EGF-like domain | |
| 19 | 17 | 36 | Elongation factor Tu GTP binding domain | |
| 6 | 6 | 12 | Helix-loop-helix DNA-binding domain | |
| 17 | 18 | 35 | Hsp70 protein | |
| 5 | 6 | 11 | KH domain | |
| 3 | 4 | 7 | SH2 domain | |
| 3 | 3 | 6 | SH3 domain | |
| 9 | 9 | 18 | Actin | |
| 153 | 194 | 347 | Ankyrin repeat | |
| 22 | 20 | 42 | PAN domain | |
| 13 | 13 | 26 | ADP-ribosylation factor family | |
| 13 | 11 | 24 | Eukaryotic aspartyl protease | |
| 53 | 73 | 126 | Cyclic nucleotide-binding domain | |
| 2 | 1 | 3 | Cytochrome c | |
| 5 | 4 | 9 | Double-stranded RNA binding motif | |
| 121 | 125 | 246 | EF hand | |
| 2 | 2 | 4 | 4Fe-4S binding domain | |
| 1 | 1 | Intermediate filament protein | ||
| 10 | 15 | 25 | Fibronectin type III domain | |
| 1 | 2 | 3 | Globin | |
| 13 | 19 | 32 | Glutathione S-transferase, C-terminal domain | |
| 6 | 6 | 12 | Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain | |
| 4 | 3 | 7 | Homeodomain | |
| 16 | 23 | 39 | Kazal-type serine protease inhibitor domain | |
| 2 | 2 | 4 | lactate/malate dehydrogenase, NAD binding domain | |
| 24 | 24 | 48 | Myosin head (motor domain) | |
| 24 | 27 | 51 | Cytochrome P450 | |
| 370 | 401 | 771 | Protein kinase domain | |
| 17 | 18 | 35 | Pyridine nucleotide-disulphide oxidoreductase | |
| 35 | 34 | 69 | Ras family | |
| 5 | 6 | 11 | Response regulator receiver domain | |
| 21 | 39 | 60 | RNase H | |
| 65 | 66 | 131 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | |
| 2 | 26 | 28 | Retroviral aspartyl protease | |
| 172 | 432 | 604 | Reverse transcriptase (RNA-dependent DNA polymerase) | |
| 1 | 1 | 2 | Copper/zinc superoxide dismutase (SODC) | |
| 2 | 1 | 3 | Iron/manganese superoxide dismutases, alpha-hairpin domain | |
| 7 | 9 | 16 | Subtilase family | |
| 76 | 85 | 161 | Sugar (and other) transporter | |
| 1 | 1 | Sushi repeat (SCR repeat) | ||
| 23 | 21 | 44 | Thioredoxin | |
| 1 | 1 | Trefoil (P-type) domain | ||
| 29 | 32 | 61 | Trypsin | |
| 3 | 7 | 10 | Thrombospondin type 1 domain | |
| 15 | 11 | 26 | Tubulin/FtsZ family, GTPase domain | |
| 4 | 2 | 6 | von Willebrand factor type A domain | |
| 44 | 66 | 110 | Zinc finger, C2H2 type | |
| 73 | 84 | 157 | Zinc finger, C3HC4 type (RING finger) | |
| 203 | 358 | 561 | Zinc knuckle | |
| 3 | 3 | 6 | Protein-tyrosine phosphatase | |
| 52 | 52 | 104 | short chain dehydrogenase | |
| 47 | 43 | 90 | Zinc-binding dehydrogenase | |
| 5 | 3 | 8 | Thiolase, N-terminal domain | |
| 4 | 4 | 8 | Beta-ketoacyl synthase, N-terminal domain | |
| 4 | 4 | 8 | 2Fe-2S iron-sulfur cluster binding domain | |
| 24 | 19 | 43 | Papain family cysteine protease | |
| 3 | 4 | 7 | Enolase, C-terminal TIM barrel domain | |
| 9 | 9 | 18 | Glutamine amidotransferase class-I | |
| 9 | 10 | 19 | TCP-1/cpn60 chaperonin family | |
| 2 | 2 | Glutamine synthetase, catalytic domain | ||
| 3 | 1 | 4 | Triosephosphate isomerase | |
| 26 | 33 | 59 | E1-E2 ATPase | |
| 13 | 8 | 21 | Core histone H2A/H2B/H3/H4 | |
| 2 | 1 | 3 | Alpha amylase, catalytic domain | |
| 2 | 1 | 3 | Phorbol esters/diacylglycerol binding domain (C1 domain) | |
| 14 | 15 | 29 | Bacterial transferase hexapeptide (six repeats) | |
| 11 | 8 | 19 | tRNA synthetases class I (I, L, M and V) | |
| 17 | 19 | 36 | Cyclin, N-terminal domain | |
| 14 | 11 | 25 | Carboxylesterase family | |
| 4 | 4 | 8 | DNA polymerase family B | |
| 3 | 1 | 4 | ATP synthase subunit C | |
| 6 | 7 | 13 | Peroxidase | |
| 2 | 2 | 4 | Beta-lactamase | |
| 50 | 47 | 97 | Calcineurin-like phosphoesterase | |
| 18 | 18 | 36 | Cellulase (glycosyl hydrolase family 5) | |
| 6 | 6 | 12 | tRNA synthetases class II (D, K and N) | |
| 47 | 45 | 92 | Mitochondrial carrier protein | |
| 1 | 1 | 2 | recA bacterial DNA recombination protein | |
| 21 | 17 | 38 | Aminotransferase class I and II | |
| 8 | 8 | 16 | Phosphoribosyl transferase domain | |
| 21 | 16 | 37 | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | |
| 3 | 1 | 4 | Phosphoglycerate kinase | |
| 1 | 1 | 2 | Ribosomal protein S4/S9 N-terminal domain | |
| 2 | 1 | 3 | Ribosomal protein S12/S23 | |
| 1 | 1 | 2 | Chaperonin 10 Kd subunit | |
| 47 | 50 | 97 | C2 domain | |
| 105 | 105 | 210 | PH domain | |
| 8 | 6 | 14 | bZIP transcription factor | |
| 22 | 21 | 43 | Aldehyde dehydrogenase family | |
| 11 | 12 | 23 | Cytochrome b5-like Heme/Steroid binding domain | |
| 2 | 2 | 4 | Oxidoreductase molybdopterin binding domain | |
| 11 | 14 | 25 | Oxidoreductase NAD-binding domain | |
| 20 | 20 | 40 | SNF2 family N-terminal domain | |
| 1 | 1 | 2 | Ribosomal protein S7p/S5e | |
| 18 | 20 | 38 | Ubiquitin-conjugating enzyme | |
| 3 | 2 | 5 | Isocitrate/isopropylmalate dehydrogenase | |
| 1 | 1 | 2 | Ribosomal Proteins L2, RNA binding domain | |
| 1 | 2 | 3 | Chitinase class I | |
| 3 | 3 | 6 | Hsp90 protein | |
| 2 | 2 | 4 | Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain | |
| 1 | 2 | 3 | Dihydrofolate reductase | |
| 21 | 29 | 50 | Cysteine-rich secretory protein family | |
| 1 | 1 | 2 | Ribosomal protein S3, C-terminal domain | |
| 8 | 8 | 16 | Annexin | |
| 10 | 14 | 24 | Eukaryotic-type carbonic anhydrase | |
| 6 | 7 | 13 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | |
| 3 | 3 | 6 | Catalase | |
| 2 | 1 | 3 | UDP-glucoronosyl and UDP-glucosyl transferase | |
| 10 | 6 | 16 | Aminotransferase class-III | |
| 1 | 1 | 2 | Ribosomal protein S19 | |
| 2 | 2 | 4 | DNA gyrase B | |
| 1 | 1 | 2 | Thiamine pyrophosphate enzyme, central domain | |
| 3 | 3 | 6 | Lyase | |
| 5 | 6 | 11 | Glutamate/Leucine/Phenylalanine/Valine dehydrogenase | |
| 4 | 4 | 8 | Adenylate and Guanylate cyclase catalytic domain | |
| 1 | 1 | 2 | ATP synthase delta (OSCP) subunit | |
| 1 | 1 | 2 | Orotidine 5'-phosphate decarboxylase / HUMPS family | |
| 2 | 2 | 4 | ATP:guanido phosphotransferase, C-terminal catalytic domain | |
| 1 | 1 | 2 | Indole-3-glycerol phosphate synthase | |
| 1 | 1 | 2 | Aromatic amino acid lyase | |
| 9 | 14 | 23 | Pyruvate kinase, barrel domain | |
| 55 | 56 | 111 | Kinesin motor domain | |
| 50 | 48 | 98 | DnaJ domain | |
| 15 | 14 | 29 | Proteasome subunit | |
| 29 | 31 | 60 | Major intrinsic protein | |
| 1 | 1 | 2 | ATP synthase | |
| 16 | 18 | 34 | Glycosyl hydrolase family 1 | |
| 11 | 11 | 22 | 3'5'-cyclic nucleotide phosphodiesterase | |
| 2 | 2 | 4 | Ribosomal protein L22p/L17e | |
| 1 | 1 | 2 | Ribosomal protein L14p/L23e | |
| 19 | 24 | 43 | Ubiquitin family | |
| 4 | 2 | 6 | Cofilin/tropomyosin-type actin-binding protein | |
| 1 | 1 | 2 | 14-3-3 protein | |
| 1 | 1 | 2 | Alkaline phosphatase | |
| 8 | 8 | 16 | Zinc carboxypeptidase | |
| 29 | 27 | 56 | Aldo/keto reductase family | |
| 60 | 68 | 128 | Myb-like DNA-binding domain | |
| 3 | 3 | 6 | Glycosyl hydrolases family 32 N-terminal domain | |
| 1 | 1 | Ribosomal protein S14p/S29e | ||
| 12 | 13 | 25 | FKBP-type peptidyl-prolyl cis-trans isomerase | |
| 6 | 6 | 12 | Glutathione peroxidase | |
| 2 | 1 | 3 | ||
| 15 | 12 | 27 | Flavodoxin | |
| 1 | 2 | 3 | ||
| 3 | 2 | 5 | Calreticulin family | |
| 2 | 5 | 7 | Common central domain of tyrosinase | |
| 2 | 1 | 3 | Thymidine kinase | |
| 4 | 5 | 9 | Aminotransferase class-V | |
| 3 | 3 | 6 | Ribonucleotide reductase, small chain | |
| 48 | 47 | 95 | DEAD/DEAH box helicase | |
| 83 | 85 | 168 | Helicase conserved C-terminal domain | |
| 1 | 1 | 2 | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) | |
| 3 | 1 | 4 | Ribosomal protein L23 | |
| 5 | 5 | 10 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain | |
| 1 | 1 | 2 | Ribosomal protein L5 | |
| 6 | 5 | 11 | Pyridoxal-dependent decarboxylase conserved domain | |
| 1 | 1 | 2 | Citrate synthase, C-terminal domain | |
| 8 | 4 | 12 | GHMP kinases N terminal domain | |
| 6 | 7 | 13 | Biotin carboxylase, N-terminal domain | |
| 1 | 1 | 2 | Tryptophan synthase alpha chain | |
| 12 | 13 | 25 | Pyridoxal-phosphate dependent enzyme | |
| 14 | 12 | 26 | NUDIX domain | |
| 3 | 6 | 9 | pfkB family carbohydrate kinase | |
| 16 | 23 | 39 | Glycosyl hydrolases family 28 | |
| 2 | 2 | 4 | Ribosomal protein L3 | |
| 2 | 2 | 4 | Ribosomal protein L11, RNA binding domain | |
| 14 | 14 | 28 | Histidine phosphatase superfamily (branch 1) | |
| 1 | 1 | Chloramphenicol acetyltransferase | ||
| 1 | 1 | 2 | Thymidylate synthase | |
| 1 | 2 | 3 | Lipoxygenase | |
| 3 | 3 | 6 | ATP synthase alpha/beta chain, C terminal domain | |
| 7 | 9 | 16 | Calponin homology (CH) domain | |
| 3 | 2 | 5 | Glutamine amidotransferases class-II | |
| 2 | 1 | 3 | Ribosomal protein S15 | |
| 1 | 1 | 2 | 'Cold-shock' DNA-binding domain | |
| 2 | 2 | 4 | Fructose-1-6-bisphosphatase, N-terminal domain | |
| 1 | 1 | 2 | Ribonucleotide reductase, all-alpha domain | |
| 1 | 1 | Ribosomal protein S2 | ||
| 1 | 1 | 2 | SRF-type transcription factor (DNA-binding and dimerisation domain) | |
| 21 | 25 | 46 | Amino acid permease | |
| 5 | 4 | 9 | Prolyl oligopeptidase family | |
| 1 | 1 | 2 | Ribosomal protein L30p/L7e | |
| 9 | 9 | 18 | Histidine phosphatase superfamily (branch 2) | |
| 3 | 3 | 6 | Aconitase family (aconitate hydratase) | |
| 7 | 5 | 12 | Glycosyl hydrolase family 10 | |
| 7 | 8 | 15 | Glycosyl hydrolases family 17 | |
| 2 | 2 | 4 | Ribosomal protein S5, N-terminal domain | |
| 4 | 3 | 7 | Nucleoside diphosphate kinase | |
| 4 | 6 | 10 | Tetraspanin family | |
| 1 | 1 | 2 | Ribosomal protein S10p/S20e | |
| 3 | 4 | 7 | Arrestin (or S-antigen), N-terminal domain | |
| 1 | 1 | Phosphoglucose isomerase | ||
| 1 | 1 | 2 | SecY translocase | |
| 1 | 1 | 2 | Ribosomal protein L6 | |
| 3 | 3 | 6 | Polyprenyl synthetase | |
| 3 | 6 | 9 | Dynamin family | |
| 1 | 1 | Biopterin-dependent aromatic amino acid hydroxylase | ||
| 3 | 3 | 6 | Transcription factor TFIID (or TATA-binding protein, TBP) | |
| 6 | 4 | 10 | Rieske [2Fe-2S] domain | |
| 9 | 12 | 21 | Biotin-requiring enzyme | |
| 1 | 1 | 2 | Phosphofructokinase | |
| 4 | 3 | 7 | Ribosomal protein S17 | |
| 1 | 1 | 2 | Hydroxymethylglutaryl-coenzyme A reductase | |
| 4 | 4 | 8 | FGGY family of carbohydrate kinases, N-terminal domain | |
| 11 | 9 | 20 | Sodium:dicarboxylate symporter family | |
| 10 | 8 | 18 | Enoyl-CoA hydratase/isomerase | |
| 2 | 2 | 4 | Ribosomal protein S9/S16 | |
| 2 | 2 | 4 | Transcription factor TFIIB repeat | |
| 6 | 6 | 12 | Cytidine and deoxycytidylate deaminase zinc-binding region | |
| 21 | 26 | 47 | Chromo (CHRromatin Organisation MOdifier) domain | |
| 10 | 10 | 20 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | |
| 1 | 4 | 5 | Malic enzyme, N-terminal domain | |
| 2 | 2 | 4 | PEP-utilising enzyme, mobile domain | |
| 1 | 1 | 2 | 6-phosphogluconate dehydrogenase, C-terminal domain | |
| 7 | 9 | 16 | Multicopper oxidase | |
| 52 | 50 | 102 | WW domain | |
| 2 | 2 | 4 | Ribosomal RNA adenine dimethylase | |
| 167 | 168 | 335 | WD domain, G-beta repeat | |
| 1 | 1 | ATP synthase, Delta/Epsilon chain, long alpha-helix domain | ||
| 8 | 8 | 16 | Heavy-metal-associated domain | |
| 7 | 8 | 15 | Adenylate kinase | |
| 3 | 3 | 6 | Phosphoglucomutase/phosphomannomutase, C-terminal domain | |
| 1 | 1 | 2 | Ribosomal protein S8 | |
| 1 | 1 | 2 | Ribosomal protein S11 | |
| 2 | 2 | 4 | LIM domain | |
| 14 | 16 | 30 | Regulator of chromosome condensation (RCC1) repeat | |
| 1 | 1 | 2 | Ribosomal protein S13/S18 | |
| 2 | 2 | 4 | chorismate binding enzyme | |
| 5 | 5 | 10 | 60s Acidic ribosomal protein | |
| 1 | 1 | CUB domain | ||
| 3 | 3 | 6 | Prenyltransferase and squalene oxidase repeat | |
| 19 | 18 | 37 | Protein kinase C terminal domain | |
| 1 | 1 | 2 | S-adenosylmethionine synthetase, N-terminal domain | |
| 18 | 15 | 33 | Bromodomain | |
| 17 | 16 | 33 | Acyl-CoA dehydrogenase, C-terminal domain | |
| 24 | 25 | 49 | Ubiquitin carboxyl-terminal hydrolase | |
| 1 | 1 | 2 | Ribosomal protein L36 | |
| 5 | 4 | 9 | Ribonuclease T2 family | |
| 16 | 20 | 36 | HSF-type DNA-binding | |
| 2 | 2 | 4 | SRP54-type protein, GTPase domain | |
| 1 | 1 | 2 | Urease alpha-subunit, N-terminal domain | |
| 14 | 16 | 30 | Serine carboxypeptidase | |
| 1 | 1 | 2 | Ribosomal protein L20 | |
| 23 | 23 | 46 | Phosphatidylinositol 3- and 4-kinase | |
| 1 | 1 | 2 | Transketolase, thiamine diphosphate binding domain | |
| 3 | 2 | 5 | WHEP-TRS domain | |
| 3 | 3 | 6 | Inositol monophosphatase family | |
| 1 | 1 | |||
| 8 | 9 | 17 | Glutaredoxin | |
| 1 | 1 | 2 | Isocitrate lyase family | |
| 2 | 2 | 4 | Serine hydroxymethyltransferase | |
| 1 | 1 | 2 | Iron-containing alcohol dehydrogenase | |
| 3 | 2 | 5 | Ribosomal protein L10 | |
| 8 | 5 | 13 | KOW motif | |
| 1 | 1 | 2 | Ribosomal protein L34 | |
| 1 | 1 | Ribosomal protein L33 | ||
| 3 | 2 | 5 | RF-1 domain | |
| 2 | 3 | 5 | Sodium:solute symporter family | |
| 1 | 1 | 2 | Imidazoleglycerol-phosphate dehydratase | |
| 1 | 1 | DNA polymerase family A | ||
| 4 | 3 | 7 | IMP dehydrogenase / GMP reductase domain | |
| 1 | 2 | 3 | Glucose-6-phosphate dehydrogenase, NAD binding domain | |
| 2 | 3 | 5 | ROK family | |
| 25 | 21 | 46 | Protein phosphatase 2C | |
| 4 | 5 | 9 | Nucleotidyl transferase | |
| 2 | 5 | 7 | Carbonic anhydrase | |
| 1 | 1 | 2 | Phosphoribulokinase / Uridine kinase family | |
| 15 | 8 | 23 | Fatty acid desaturase | |
| 5 | 5 | 10 | MutS domain V | |
| 1 | 1 | 2 | Delta-aminolevulinic acid dehydratase | |
| 1 | 1 | 2 | Arginase family | |
| 9 | 8 | 17 | MCM P-loop domain | |
| 17 | 16 | 33 | FHA domain | |
| 28 | 26 | 54 | AMP-binding enzyme | |
| 1 | 1 | 2 | G-protein alpha subunit | |
| 6 | 4 | 10 | HMG (high mobility group) box | |
| 1 | 1 | NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 | ||
| 4 | 3 | 7 | His Kinase A (phospho-acceptor) domain | |
| 21 | 27 | 48 | Armadillo/beta-catenin-like repeat | |
| 87 | 94 | 181 | Tetratricopeptide repeat | |
| 41 | 57 | 98 | Ion transport protein | |
| 2 | 2 | 4 | DNA gyrase/topoisomerase IV, subunit A | |
| 1 | 1 | Death domain | ||
| 8 | 6 | 14 | BRCA1 C Terminus (BRCT) domain | |
| 5 | 5 | 10 | Glycosyl transferases group 1 | |
| 2 | 3 | 5 | Glycosyl transferase family 2 | |
| 11 | 11 | 22 | SAM domain (Sterile alpha motif) | |
| 3 | 2 | 5 | linker histone H1 and H5 family | |
| 2 | 1 | 3 | Ribosomal protein L7/L12 C-terminal domain | |
| 7 | 12 | 19 | Pectate lyase | |
| 1 | 1 | 2 | Urease, gamma subunit | |
| 2 | 3 | 5 | CoA-ligase | |
| 3 | 1 | 4 | Phosphopantetheine attachment site | |
| 1 | 2 | 3 | Formyl transferase | |
| 10 | 9 | 19 | Metallopeptidase family M24 | |
| 86 | 86 | 172 | Leucine Rich Repeat | |
| 31 | 23 | 54 | alpha/beta hydrolase fold | |
| 4 | 3 | 7 | RNA polymerase Rpb2, domain 6 | |
| 7 | 8 | 15 | PB1 domain | |
| 2 | 3 | 5 | Staphylococcal nuclease homologue | |
| 17 | 18 | 35 | Rab-GTPase-TBC domain | |
| 1 | 1 | 2 | Tudor domain | |
| 14 | 9 | 23 | Zinc finger, ZZ type | |
| 2 | 2 | 4 | HRDC domain | |
| 18 | 17 | 35 | CBS domain | |
| 2 | 2 | 4 | Ribosomal protein L13 | |
| 2 | 2 | 4 | Ribosomal protein L4/L1 family | |
| 1 | 1 | 2 | Clp protease | |
| 3 | 4 | 7 | S1 RNA binding domain | |
| 1 | 1 | HIUase/Transthyretin family | ||
| 12 | 7 | 19 | AhpC/TSA family | |
| 5 | 4 | 9 | tRNA synthetases class I (W and Y) | |
| 10 | 11 | 21 | Rhodanese-like domain | |
| 1 | 1 | Universal stress protein family | ||
| 27 | 31 | 58 | Acetyltransferase (GNAT) family | |
| 1 | 1 | 2 | SecE/Sec61-gamma subunits of protein translocation complex | |
| 2 | 2 | 4 | C-terminal regulatory domain of Threonine dehydratase | |
| 4 | 3 | 7 | AIR synthase related protein, N-terminal domain | |
| 10 | 9 | 19 | tRNA synthetase class II core domain (G, H, P, S and T) | |
| 4 | 3 | 7 | SpoU rRNA Methylase family | |
| 3 | 5 | 8 | Phage integrase family | |
| 3 | 3 | 6 | Tetrapyrrole (Corrin/Porphyrin) Methylases | |
| 2 | 1 | 3 | Glycosyl transferase family, a/b domain | |
| 33 | 31 | 64 | PDZ domain | |
| 1 | 1 | 2 | Class II Aldolase and Adducin N-terminal domain | |
| 1 | 1 | 2 | Diacylglycerol kinase accessory domain | |
| 7 | 6 | 13 | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | |
| 1 | 1 | Fes/CIP4, and EFC/F-BAR homology domain | ||
| 82 | 95 | 177 | IQ calmodulin-binding motif | |
| 3 | 4 | 7 | Phosphoinositide 3-kinase family, accessory domain (PIK domain) | |
| 16 | 20 | 36 | Phospholipase D Active site motif | |
| 6 | 7 | 13 | Regulator of G protein signaling domain | |
| 3 | 3 | 6 | GTPase-activator protein for Ras-like GTPase | |
| 3 | 3 | 6 | RasGEF domain | |
| 1 | 1 | 2 | RasGEF N-terminal motif | |
| 3 | 5 | 8 | RhoGAP domain | |
| 2 | 2 | 4 | RhoGEF domain | |
| 10 | 9 | 19 | SPRY domain | |
| 3 | 3 | 6 | RNA polymerase Rpb1, domain 2 | |
| 1 | 1 | 2 | Guanylate kinase | |
| 4 | 4 | 8 | Gelsolin repeat | |
| 13 | 16 | 29 | UBA/TS-N domain | |
| 35 | 35 | 70 | PHD-finger | |
| 2 | 2 | 4 | Filamin/ABP280 repeat | |
| 26 | 25 | 51 | HECT-domain (ubiquitin-transferase) | |
| 5 | 6 | 11 | Helix-hairpin-helix motif | |
| 1 | 1 | BRCA2 repeat | ||
| 3 | 3 | 6 | MSP (Major sperm protein) domain | |
| 3 | 5 | 8 | Ribonuclease III domain | |
| 2 | 2 | 4 | Region in Clathrin and VPS | |
| 3 | 3 | 6 | RanBP1 domain | |
| 4 | 4 | 8 | PPIC-type PPIASE domain | |
| 11 | 8 | 19 | Zn-finger in Ran binding protein and others | |
| 27 | 30 | 57 | Zinc finger C-x8-C-x5-C-x3-H type (and similar) | |
| 5 | 4 | 9 | B-box zinc finger | |
| 3 | 4 | 7 | Poly(ADP-ribose) polymerase catalytic domain | |
| 1 | 1 | 2 | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | |
| 19 | 22 | 41 | F-box domain | |
| 2 | 2 | 4 | Elongation factor 1 gamma, conserved domain | |
| 5 | 6 | 11 | Calpain family cysteine protease | |
| 10 | 10 | 20 | CRAL/TRIO domain | |
| 10 | 10 | 20 | BTB/POZ domain | |
| 9 | 10 | 19 | Ricin-type beta-trefoil lectin domain | |
| 9 | 8 | 17 | Voltage gated chloride channel | |
| 6 | 13 | 19 | GDSL-like Lipase/Acylhydrolase | |
| 1 | 1 | 2 | Poly-adenylate binding protein, unique domain | |
| 1 | 1 | 2 | POLO box duplicated region | |
| 45 | 45 | 90 | ABC transporter transmembrane region | |
| 219 | 570 | 789 | Integrase core domain | |
| 5 | 6 | 11 | FAD binding domain | |
| 1 | 1 | 2 | Condensation domain | |
| 1 | 1 | 2 | S-adenosyl-L-homocysteine hydrolase, NAD binding domain | |
| 1 | 1 | 2 | ribosomal L5P family C-terminus | |
| 8 | 5 | 13 | Insulinase (Peptidase family M16) | |
| 5 | 5 | 10 | Dehydrogenase E1 component | |
| 1 | 1 | Lumazine binding domain | ||
| 7 | 8 | 15 | Elongation factor G C-terminus | |
| 3 | 3 | 6 | HMGL-like | |
| 4 | 4 | 8 | DnaJ central domain | |
| 2 | 2 | 4 | Sulfotransferase domain | |
| 1 | 1 | 2 | Starch binding domain | |
| 2 | 2 | 4 | Ribosomal protein L1p/L10e family | |
| 9 | 12 | 21 | Cation transporting ATPase, C-terminus | |
| 12 | 13 | 25 | Cation transporter/ATPase, N-terminus | |
| 2 | 1 | 3 | dUTPase | |
| 3 | 3 | 6 | Aconitase C-terminal domain | |
| 7 | 7 | 14 | Amino acid kinase family | |
| 1 | 1 | 2 | N-(5'phosphoribosyl)anthranilate (PRA) isomerase | |
| 5 | 3 | 8 | Acyl transferase domain | |
| 1 | 1 | 2 | Urease beta subunit | |
| 1 | 2 | 3 | Dihydrodipicolinate synthetase family | |
| 46 | 52 | 98 | haloacid dehalogenase-like hydrolase | |
| 1 | 1 | 2 | Glycosyl hydrolases family 2 | |
| 2 | 3 | 5 | Glycosyl hydrolases family 18 | |
| 1 | 1 | 2 | Proliferating cell nuclear antigen, N-terminal domain | |
| 1 | 1 | Translation initiation factor IF-3, C-terminal domain | ||
| 1 | 1 | Acylphosphatase | ||
| 2 | 1 | 3 | Adenylosuccinate synthetase | |
| 1 | 1 | 2 | Asparaginase, N-terminal | |
| 3 | 3 | 6 | Inorganic pyrophosphatase | |
| 26 | 38 | 64 | NADH:flavin oxidoreductase / NADH oxidase family | |
| 2 | 1 | 3 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | |
| 4 | 4 | 8 | HhH-GPD superfamily base excision DNA repair protein | |
| 1 | 2 | 3 | AIR carboxylase | |
| 10 | 10 | 20 | GMC oxidoreductase | |
| 2 | 1 | 3 | Asparagine synthase | |
| 3 | 5 | 8 | Fungal cellulose binding domain | |
| 2 | 2 | 4 | EF-1 guanine nucleotide exchange domain | |
| 2 | 2 | 4 | Homoserine dehydrogenase | |
| 3 | 3 | 6 | tRNA synthetases class I (E and Q), catalytic domain | |
| 2 | 2 | 4 | tRNA synthetases class I (R) | |
| 5 | 8 | 13 | XPG N-terminal domain | |
| 7 | 8 | 15 | Metallo-beta-lactamase superfamily | |
| 1 | 1 | 2 | F5/8 type C domain | |
| 7 | 7 | 14 | Choline/Carnitine o-acyltransferase | |
| 1 | 1 | 2 | Putative esterase | |
| 1 | 1 | 2 | Ferrochelatase | |
| 4 | 3 | 7 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | |
| 1 | 1 | 2 | Arginosuccinate synthase | |
| 1 | 1 | 2 | Electron transfer flavoprotein FAD-binding domain | |
| 3 | 3 | 6 | RNB domain | |
| 13 | 10 | 23 | Dioxygenase | |
| 2 | 3 | 5 | Diacylglycerol kinase catalytic domain | |
| 12 | 12 | 24 | Dual specificity phosphatase, catalytic domain | |
| 2 | 2 | 4 | MyTH4 domain | |
| 5 | 4 | 9 | ||
| 1 | 1 | 2 | P21-Rho-binding domain | |
| 67 | 61 | 128 | PX domain | |
| 5 | 5 | 10 | UBX domain | |
| 3 | 2 | 5 | VHS domain | |
| 2 | 2 | 4 | Phosphoinositide 3-kinase C2 | |
| 4 | 4 | 8 | DAHP synthetase I family | |
| 5 | 6 | 11 | Carbon-nitrogen hydrolase | |
| 2 | 2 | 4 | Prephenate dehydratase | |
| 6 | 6 | 12 | Syntaxin | |
| 3 | 4 | 7 | Pumilio-family RNA binding repeat | |
| 4 | 3 | 7 | Histone-like transcription factor (CBF/NF-Y) and archaeal histone | |
| 3 | 2 | 5 | Pterin binding enzyme | |
| 1 | 1 | 2 | ER lumen protein retaining receptor | |
| 2 | 2 | 4 | Glycoprotease family | |
| 1 | 1 | 2 | Histidinol dehydrogenase | |
| 3 | 3 | 6 | impB/mucB/samB family | |
| 2 | 1 | 3 | ||
| 1 | 1 | 2 | Ribosomal L15 | |
| 1 | 1 | 2 | Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A | |
| 1 | 1 | 2 | Ribosomal prokaryotic L21 protein | |
| 1 | 1 | 2 | Ribosomal L28 family | |
| 1 | 1 | 2 | Ribosomal L29 protein | |
| 1 | 1 | Ribosomal L39 protein | ||
| 1 | 1 | 2 | Ribosomal S17 | |
| 1 | 3 | 4 | Ribulose-phosphate 3 epimerase family | |
| 1 | 1 | 2 | Translationally controlled tumour protein | |
| 4 | 7 | 11 | Glycosyl hydrolase family 7 | |
| 1 | 1 | 2 | AP2 domain | |
| 7 | 8 | 15 | RNA pseudouridylate synthase | |
| 11 | 8 | 19 | Histone deacetylase domain | |
| 10 | 8 | 18 | POT family | |
| 3 | 4 | 7 | PWWP domain | |
| 38 | 54 | 92 | SET domain | |
| 2 | 3 | 5 | Isochorismatase family | |
| 1 | 1 | 2 | Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast | |
| 5 | 9 | 14 | XPG I-region | |
| 1 | 1 | 2 | Acetokinase family | |
| 5 | 4 | 9 | DNA photolyase | |
| 3 | 3 | 6 | Nitroreductase family | |
| 3 | 3 | 6 | Cytosol aminopeptidase family, catalytic domain | |
| 13 | 17 | 30 | Sulfatase | |
| 2 | 4 | 6 | 6,7-dimethyl-8-ribityllumazine synthase | |
| 1 | 1 | 2 | Ribosomal protein S16 | |
| 6 | 5 | 11 | Acyl CoA binding protein | |
| 3 | 3 | 6 | Cullin family | |
| 1 | 1 | Elongation factor TS | ||
| 3 | 3 | 6 | FAD binding domain | |
| 12 | 12 | 24 | EamA-like transporter family | |
| 5 | 4 | 9 | ||
| 10 | 10 | 20 | ThiF family | |
| 1 | 1 | 2 | Ribosomal family S4e | |
| 1 | 1 | 2 | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily | |
| 7 | 8 | 15 | Ammonium Transporter Family | |
| 11 | 11 | 22 | Sulfate permease family | |
| 1 | 1 | MATH domain | ||
| 2 | 2 | 4 | Uncharacterized protein family UPF0004 | |
| 3 | 3 | 6 | Dehydratase family | |
| 1 | 1 | Transaldolase/Fructose-6-phosphate aldolase | ||
| 2 | 2 | 4 | Mechanosensitive ion channel | |
| 2 | 2 | 4 | GTP cyclohydrolase II | |
| 2 | 2 | 4 | 3,4-dihydroxy-2-butanone 4-phosphate synthase | |
| 4 | 4 | 8 | Adaptor complexes medium subunit family | |
| 5 | 4 | 9 | Exonuclease | |
| 1 | 1 | 2 | Dipeptidyl peptidase IV (DPP IV) N-terminal region | |
| 25 | 28 | 53 | Glycosyl hydrolase family 3 N terminal domain | |
| 1 | 1 | Ribosomal protein L44 | ||
| 1 | 1 | 2 | Sodium:sulfate symporter transmembrane region | |
| 1 | 1 | 2 | DNA-dependent RNA polymerase | |
| 1 | 1 | 2 | FAD binding domain in molybdopterin dehydrogenase | |
| 1 | 1 | 2 | Glycosyl transferase family 4 | |
| 2 | 2 | 4 | Nucleosome assembly protein (NAP) | |
| 4 | 4 | 8 | Synaptobrevin | |
| 1 | 1 | 2 | GMP synthase C terminal domain | |
| 4 | 2 | 6 | Adenosine/AMP deaminase | |
| 26 | 21 | 47 | Elicitin | |
| 6 | 6 | 12 | Oxidoreductase FAD-binding domain | |
| 1 | 1 | 2 | Thioesterase domain | |
| 2 | 2 | 4 | Histidine biosynthesis protein | |
| 8 | 8 | 16 | Glycosyltransferase family 20 | |
| 1 | 1 | 2 | UDP-glucose/GDP-mannose dehydrogenase family, central domain | |
| 2 | 2 | 4 | Carbamoyl-phosphate synthase small chain, CPSase domain | |
| 5 | 4 | 9 | PAS fold | |
| 2 | 2 | 4 | ||
| 3 | 3 | 6 | Probable molybdopterin binding domain | |
| 7 | 6 | 13 | Sec1 family | |
| 2 | 2 | 4 | GDP dissociation inhibitor | |
| 12 | 14 | 26 | Sodium/hydrogen exchanger family | |
| 2 | 2 | 4 | RNA polymerase Rpb3/RpoA insert domain | |
| 4 | 4 | 8 | Inward rectifier potassium channel transmembrane domain | |
| 4 | 4 | 8 | Initiation factor 2 subunit family | |
| 1 | 1 | 2 | PQQ enzyme repeat | |
| 1 | 1 | 2 | Electron transfer flavoprotein domain | |
| 2 | 2 | Uricase | ||
| 1 | 1 | 2 | Ribosomal S3Ae family | |
| 1 | 1 | Ribosomal L27 protein | ||
| 4 | 3 | 7 | GTP1/OBG | |
| 1 | 1 | 2 | Gamma-glutamyltranspeptidase | |
| 1 | 1 | 2 | Ribosomal L40e family | |
| 1 | 1 | 2 | GrpE | |
| 4 | 3 | 7 | TatD related DNase | |
| 2 | 1 | 3 | Inhibitor of apoptosis-promoting Bax1 | |
| 1 | 1 | Eukaryotic DNA topoisomerase I, catalytic core | ||
| 1 | 4 | 5 | Dynamin central region | |
| 3 | 5 | 8 | Carboxyl transferase domain | |
| 2 | 2 | 4 | UbiA prenyltransferase family | |
| 1 | 1 | DegT/DnrJ/EryC1/StrS aminotransferase family | ||
| 3 | 2 | 5 | Endoribonuclease L-PSP | |
| 2 | 2 | Phosphorylase superfamily | ||
| 1 | 1 | Cadherin cytoplasmic region | ||
| 1 | 1 | Initiator Replication protein | ||
| 3 | 3 | 6 | Cys/Met metabolism PLP-dependent enzyme | |
| 5 | 8 | 13 | Glycosyl hydrolases family 31 | |
| 2 | 3 | 5 | NADH ubiquinone oxidoreductase, 20 Kd subunit | |
| 1 | 1 | 2 | Amino-transferase class IV | |
| 5 | 5 | 10 | CDP-alcohol phosphatidyltransferase | |
| 1 | 2 | 3 | Calpain large subunit, domain III | |
| 4 | 5 | 9 | ATP dependent DNA ligase domain | |
| 2 | 2 | 4 | FMN-dependent dehydrogenase | |
| 1 | 1 | 2 | Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain | |
| 1 | 2 | 3 | Glycosyl hydrolases family 38 N-terminal domain | |
| 2 | 2 | 4 | Nitrite and sulphite reductase 4Fe-4S domain | |
| 2 | 2 | 4 | Presenilin | |
| 4 | 16 | 20 | Cutinase | |
| 1 | 1 | 2 | Ribosomal protein S18 | |
| 3 | 2 | 5 | Ubiquitin carboxyl-terminal hydrolase, family 1 | |
| 2 | 2 | 4 | ||
| 2 | 1 | 3 | Ribosomal protein S19e | |
| 1 | 1 | 2 | Ribosomal protein S6e | |
| 13 | 19 | 32 | Pectinesterase | |
| 4 | 3 | 7 | Transcription factor S-II (TFIIS) | |
| 1 | 1 | 2 | Surface antigen | |
| 2 | 3 | 5 | emp24/gp25L/p24 family/GOLD | |
| 2 | 1 | 3 | NifU-like domain | |
| 1 | 1 | Cyclin-dependent kinase regulatory subunit | ||
| 1 | 2 | 3 | Asparaginase | |
| 1 | 1 | Dihydrodipicolinate reductase, N-terminus | ||
| 1 | 2 | 3 | F-actin capping protein, beta subunit | |
| 3 | 3 | Fructose-bisphosphate aldolase class-II | ||
| 2 | 2 | 4 | Semialdehyde dehydrogenase, NAD binding domain | |
| 1 | 2 | 3 | DNA mismatch repair protein, C-terminal domain | |
| 1 | 1 | 2 | Dephospho-CoA kinase | |
| 4 | 5 | 9 | MAPEG family | |
| 1 | 1 | 2 | G10 protein | |
| 1 | 1 | 2 | Heme oxygenase | |
| 1 | 1 | 2 | Succinate dehydrogenase/Fumarate reductase transmembrane subunit | |
| 2 | 3 | 5 | CD36 family | |
| 1 | 1 | 2 | DNA topoisomerase | |
| 1 | 1 | 2 | Elongation factor P (EF-P) OB domain | |
| 1 | 1 | Enhancer of rudimentary | ||
| 1 | 1 | 2 | Glucose inhibited division protein A | |
| 4 | 3 | 7 | Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) | |
| 2 | 1 | 3 | RNA 3'-terminal phosphate cyclase | |
| 7 | 7 | 14 | 3' exoribonuclease family, domain 1 | |
| 2 | 3 | 5 | tRNA pseudouridine synthase D (TruD) | |
| 2 | 1 | 3 | Coenzyme A transferase | |
| 6 | 7 | 13 | SPFH domain / Band 7 family | |
| 8 | 10 | 18 | Cytidylyltransferase family | |
| 1 | 1 | 2 | GDA1/CD39 (nucleoside phosphatase) family | |
| 5 | 4 | 9 | GNS1/SUR4 family | |
| 1 | 1 | 2 | Hydroxymethylglutaryl-coenzyme A synthase N terminal | |
| 1 | 1 | Inosine-uridine preferring nucleoside hydrolase | ||
| 1 | 1 | 2 | Ribosomal protein L21e | |
| 1 | 1 | 2 | Ribosomal protein L36e | |
| 2 | 2 | 4 | Ribosomal protein L6e | |
| 3 | 1 | 4 | Phosphatidylethanolamine-binding protein | |
| 1 | 1 | 2 | ||
| 4 | 4 | 8 | RIO1 family | |
| 8 | 6 | 14 | Tub family | |
| 3 | 3 | 6 | Alanine racemase, N-terminal domain | |
| 1 | 1 | 2 | Uncharacterized protein family UPF0016 | |
| 3 | 3 | 6 | PP-loop family | |
| 1 | 1 | 2 | Shwachman-Bodian-Diamond syndrome (SBDS) protein | |
| 1 | 1 | 2 | SNO glutamine amidotransferase family | |
| 2 | 1 | 3 | Urocanase Rossmann-like domain | |
| 1 | 1 | 2 | Translation initiation factor 1A / IF-1 | |
| 1 | 1 | 2 | Asp/Glu/Hydantoin racemase | |
| 3 | 8 | 11 | Copper amine oxidase, enzyme domain | |
| 1 | 1 | 2 | Dihydroorotate dehydrogenase | |
| 1 | 1 | 2 | Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase | |
| 3 | 4 | 7 | Macrophage migration inhibitory factor (MIF) | |
| 7 | 7 | 14 | 16S rRNA methyltransferase RsmB/F | |
| 1 | 1 | 2 | RNA polymerase Rpb5, C-terminal domain | |
| 1 | 1 | RNA polymerase Rpb6 | ||
| 3 | 2 | 5 | RNA polymerase Rpb3/Rpb11 dimerisation domain | |
| 1 | 1 | RNA polymerases N / 8 kDa subunit | ||
| 1 | 1 | 2 | Peptidyl-tRNA hydrolase | |
| 1 | 1 | 2 | Ribosomal protein L17 | |
| 1 | 1 | 2 | Ribosomal protein L31e | |
| 1 | 1 | 2 | Ribosomal protein L34e | |
| 1 | 1 | 2 | Ribosomal protein S28e | |
| 2 | 2 | 4 | Ribosomal protein S8e | |
| 1 | 1 | 2 | Shikimate kinase | |
| 2 | 2 | 4 | Trehalase | |
| 3 | 2 | 5 | Uncharacterized protein family UPF0029 | |
| 5 | 5 | 10 | Dihydrouridine synthase (Dus) | |
| 1 | 1 | 2 | Uroporphyrinogen decarboxylase (URO-D) | |
| 4 | 3 | 7 | ubiE/COQ5 methyltransferase family | |
| 3 | 2 | 5 | NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus | |
| 1 | 2 | 3 | Adenylate cyclase associated (CAP) N terminal | |
| 3 | 2 | 5 | Casein kinase II regulatory subunit | |
| 5 | 6 | 11 | Clathrin adaptor complex small chain | |
| 2 | 2 | 4 | Coproporphyrinogen III oxidase | |
| 5 | 2 | 7 | Dynein light chain type 1 | |
| 1 | 1 | 2 | Ergosterol biosynthesis ERG4/ERG24 family | |
| 1 | 1 | 2 | DNA/RNA non-specific endonuclease | |
| 1 | 1 | 2 | Mur ligase family, catalytic domain | |
| 1 | 1 | 2 | GTP cyclohydrolase I | |
| 5 | 3 | 8 | HIT domain | |
| 2 | 2 | Mannitol dehydrogenase Rossmann domain | ||
| 2 | 2 | 4 | Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain | |
| 1 | 1 | 2 | Oxysterol-binding protein | |
| 1 | 1 | 2 | Phosphomannose isomerase type I | |
| 2 | 2 | 4 | Protein prenyltransferase alpha subunit repeat | |
| 1 | 1 | 2 | Ribosomal protein L19 | |
| 2 | 2 | 4 | Ribosomal protein L24e | |
| 1 | 1 | Ribosomal protein L35Ae | ||
| 7 | 7 | 14 | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family | |
| 1 | 1 | Ribosomal protein S21e | ||
| 1 | 1 | 2 | Ribosomal protein S7e | |
| 3 | 2 | 5 | Translation initiation factor SUI1 | |
| 2 | 2 | 4 | Putative undecaprenyl diphosphate synthase | |
| 1 | 1 | 2 | Carbohydrate kinase | |
| 1 | 1 | 2 | Thioredoxin-like [2Fe-2S] ferredoxin | |
| 1 | 1 | 2 | SAICAR synthetase | |
| 1 | 1 | 2 | Alanine dehydrogenase/PNT, C-terminal domain | |
| 7 | 6 | 13 | Aldose 1-epimerase | |
| 1 | 1 | 2 | Chorismate synthase | |
| 2 | 2 | 4 | Cytochrome c/c1 heme lyase | |
| 2 | 3 | 5 | FAD dependent oxidoreductase | |
| 1 | 1 | 2 | F-actin capping protein alpha subunit | |
| 1 | 1 | 2 | Formate--tetrahydrofolate ligase | |
| 1 | 1 | 2 | Fibrillarin | |
| 2 | 2 | 4 | Malate synthase | |
| 1 | 1 | 2 | Ribosomal protein L19e | |
| 1 | 1 | 2 | Ribosomal protein L9, N-terminal domain | |
| 1 | 1 | 2 | Ribosomal protein S24e | |
| 1 | 1 | 2 | Ribosomal protein S26e | |
| 2 | 1 | 3 | Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold | |
| 1 | 1 | 2 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) | |
| 4 | 7 | 11 | Phosphoenolpyruvate carboxykinase | |
| 1 | 1 | 2 | Ribosomal protein L13e | |
| 1 | 1 | 2 | Telomere recombination | |
| 1 | 1 | 2 | Glycosyl hydrolases family 35 | |
| 9 | 8 | 17 | CAP-Gly domain | |
| 1 | 1 | 2 | ||
| 4 | 3 | 7 | LacY proton/sugar symporter | |
| 1 | 1 | 2 | Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain | |
| 2 | 2 | 4 | Pyruvate phosphate dikinase, PEP/pyruvate binding domain | |
| 1 | 1 | 2 | Polypeptide deformylase | |
| 1 | 1 | Pterin 4 alpha carbinolamine dehydratase | ||
| 3 | 3 | 6 | mRNA capping enzyme, catalytic domain | |
| 8 | 7 | 15 | OB-fold nucleic acid binding domain | |
| 8 | 6 | 14 | Glycosyl hydrolases family 6 | |
| 19 | 19 | 38 | Kelch motif | |
| 2 | 2 | 4 | Ribonuclease HII | |
| 5 | 5 | 10 | ||
| 64 | 72 | 136 | FYVE zinc finger | |
| 5 | 5 | 10 | Sec7 domain | |
| 8 | 7 | 15 | NAD dependent epimerase/dehydratase family | |
| 1 | 4 | 5 | Porphobilinogen deaminase, dipyromethane cofactor binding domain | |
| 1 | 2 | 3 | SIS domain | |
| 1 | 1 | 2 | Helix-turn-helix | |
| 3 | 3 | Probable transposase | ||
| 1 | 1 | Ribosomal L25p family | ||
| 2 | 2 | 4 | ARID/BRIGHT DNA binding domain | |
| 2 | 2 | 4 | Clathrin propeller repeat | |
| 10 | 8 | 18 | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | |
| 14 | 16 | 30 | PCI domain | |
| 3 | 3 | 6 | Astacin (Peptidase family M12A) | |
| 2 | 2 | 4 | tRNA synthetases class I (C) catalytic domain | |
| 9 | 8 | 17 | Oxidoreductase family, NAD-binding Rossmann fold | |
| 2 | 2 | 4 | tRNA synthetases class II core domain (F) | |
| 2 | 2 | 4 | tRNA synthetases class II (A) | |
| 8 | 9 | 17 | Putative GTPase activating protein for Arf | |
| 5 | 6 | 11 | tRNA pseudouridine synthase | |
| 2 | 2 | 4 | ENTH domain | |
| 3 | 4 | 7 | Jacalin-like lectin domain | |
| 17 | 14 | 31 | LSM domain | |
| 2 | 3 | 5 | R3H domain | |
| 2 | 2 | 4 | Amidase | |
| 1 | 1 | 2 | BAH domain | |
| 4 | 1 | 5 | AN1-like Zinc finger | |
| 1 | 1 | 2 | Hsp33 protein | |
| 3 | 3 | 6 | Peptidase family M13 | |
| 3 | 3 | 6 | Peptidase family M3 | |
| 7 | 8 | 15 | Peptidase family M1 domain | |
| 2 | 2 | 4 | Peptidase family M41 | |
| 3 | 4 | 7 | Peptidase family M48 | |
| 1 | 4 | 5 | NHL repeat | |
| 1 | 1 | 2 | Acetohydroxy acid isomeroreductase, catalytic domain | |
| 2 | 3 | 5 | Low molecular weight phosphotyrosine protein phosphatase | |
| 1 | 1 | 2 | MAGE family | |
| 1 | 4 | 5 | Leishmanolysin | |
| 5 | 4 | 9 | Eukaryotic porin | |
| 1 | 1 | Leucine rich repeat N-terminal domain | ||
| 2 | 2 | 4 | GRIP domain | |
| 3 | 3 | 6 | Skp1 family, dimerisation domain | |
| 4 | 4 | 8 | Cytidylyltransferase-like | |
| 1 | 1 | GA module | ||
| 1 | 1 | 2 | Pyroglutamyl peptidase | |
| 2 | 1 | 3 | PUA domain | |
| 1 | 1 | 2 | Class-II DAHP synthetase family | |
| 2 | 2 | 4 | LysM domain | |
| 6 | 5 | 11 | S4 domain | |
| 1 | 1 | 2 | PWI domain | |
| 3 | 2 | 5 | IBR domain, a half RING-finger domain | |
| 1 | 1 | 2 | Type I 3-dehydroquinase | |
| 1 | 1 | 2 | Shikimate / quinate 5-dehydrogenase | |
| 46 | 52 | 98 | Transmembrane amino acid transporter protein | |
| 1 | 1 | 2 | Frataxin-like domain | |
| 1 | 2 | 3 | GXGXG motif | |
| 1 | 1 | 2 | FAD binding domain | |
| 1 | 1 | 2 | ||
| 1 | 1 | 2 | V-type ATPase 116kDa subunit family | |
| 2 | 8 | 10 | Transposase | |
| 2 | 2 | 4 | Glycosyl transferase family 8 | |
| 1 | 1 | 2 | Phosphoribosyl-AMP cyclohydrolase | |
| 1 | 1 | 2 | Phosphoribosyl-ATP pyrophosphohydrolase | |
| 16 | 15 | 31 | Phosphatidylinositol-4-phosphate 5-Kinase | |
| 1 | 1 | 2 | Major Vault Protein repeat domain | |
| 1 | 1 | 2 | Phosphoadenosine phosphosulfate reductase family | |
| 2 | 2 | 4 | TruB family pseudouridylate synthase (N terminal domain) | |
| 1 | 1 | 2 | Respiratory-chain NADH dehydrogenase 51 Kd subunit | |
| 2 | 2 | 4 | ATP-NAD kinase | |
| 2 | 1 | 3 | Phosphate acetyl/butaryl transferase | |
| 2 | 2 | 4 | Iron-sulphur cluster biosynthesis | |
| 2 | 2 | 4 | Polysaccharide deacetylase | |
| 16 | 21 | 37 | DHHC palmitoyltransferase | |
| 6 | 5 | 11 | Glycosyl hydrolase family 47 | |
| 13 | 12 | 25 | PPR repeat | |
| 1 | 1 | 2 | Adenosylmethionine decarboxylase | |
| 7 | 10 | 17 | CorA-like Mg2+ transporter protein | |
| 8 | 12 | 20 | Cation efflux family | |
| 6 | 7 | 13 | Peptidase family M20/M25/M40 | |
| 2 | 2 | 4 | Bacterial extracellular solute-binding protein | |
| 12 | 11 | 23 | Acyltransferase | |
| 14 | 18 | 32 | MatE | |
| 8 | 5 | 13 | DnaJ C terminal domain | |
| 3 | 3 | 6 | Fumarylacetoacetate (FAA) hydrolase family | |
| 1 | 2 | 3 | Spermine/spermidine synthase domain | |
| 11 | 16 | 27 | FAD binding domain | |
| 3 | 4 | 7 | Natural resistance-associated macrophage protein | |
| 8 | 7 | 15 | PAP2 superfamily | |
| 2 | 2 | 4 | Aminomethyltransferase folate-binding domain | |
| 5 | 5 | 10 | MaoC like domain | |
| 2 | 1 | 3 | Adenylylsulphate kinase | |
| 8 | 6 | 14 | G-patch domain | |
| 6 | 4 | 10 | Putative tRNA binding domain | |
| 21 | 22 | 43 | GAF domain | |
| 3 | 3 | 6 | 6-phosphofructo-2-kinase | |
| 1 | 1 | 2 | NifU-like N terminal domain | |
| 5 | 4 | 9 | Flavin containing amine oxidoreductase | |
| 1 | 1 | 2 | AI-2E family transporter | |
| 4 | 4 | 8 | Cyclin M transmembrane N-terminal domain | |
| 1 | 1 | 2 | O-methyltransferase | |
| 1 | 1 | 2 | Glycine cleavage H-protein | |
| 2 | 1 | 3 | ||
| 1 | 1 | 2 | Ribosomal protein S27a | |
| 9 | 9 | 18 | Adaptin N terminal region | |
| 3 | 3 | 6 | Protein phosphatase 2A regulatory B subunit (B56 family) | |
| 3 | 3 | Transposase DDE domain | ||
| 7 | 6 | 13 | 3'-5' exonuclease | |
| 1 | 1 | Proline dehydrogenase | ||
| 2 | 2 | 4 | MutS domain I | |
| 2 | 2 | 4 | Peptide methionine sulfoxide reductase | |
| 2 | 1 | 3 | Hpt domain | |
| 1 | 1 | Ribosomal protein L35 | ||
| 3 | 3 | 6 | Choline/ethanolamine kinase | |
| 1 | 1 | 2 | ATP phosphoribosyltransferase | |
| 1 | 1 | 2 | Phosphotransferase enzyme family | |
| 1 | 1 | 2 | SelR domain | |
| 1 | 1 | 2 | Methylmalonyl-CoA mutase | |
| 2 | 2 | 4 | Chitin synthase | |
| 1 | 1 | 2 | Conserved region in glutamate synthase | |
| 5 | 4 | 9 | 4'-phosphopantetheinyl transferase superfamily | |
| 2 | 2 | 4 | Peptidase C13 family | |
| 4 | 4 | 8 | Eukaryotic initiation factor 4E | |
| 1 | 1 | 2 | Ribosomal protein L32 | |
| 3 | 3 | 6 | CobQ/CobB/MinD/ParA nucleotide binding domain | |
| 1 | 1 | 2 | Myo-inositol-1-phosphate synthase | |
| 10 | 10 | 20 | Macro domain | |
| 1 | 1 | 2 | Ribosomal protein S27 | |
| 8 | 11 | 19 | Glycosyl hydrolase family 12 | |
| 1 | 1 | 2 | Metalloenzyme superfamily | |
| 2 | 2 | 4 | Proteolipid membrane potential modulator | |
| 2 | 1 | 3 | SOR/SNZ family | |
| 1 | 1 | 2 | Riboflavin kinase | |
| 5 | 3 | 8 | Rhomboid family | |
| 5 | 5 | 10 | Sodium/calcium exchanger protein | |
| 2 | 2 | 4 | Queuine tRNA-ribosyltransferase | |
| 5 | 4 | 9 | UTP--glucose-1-phosphate uridylyltransferase | |
| 1 | 1 | 2 | Transcriptional regulator | |
| 2 | 2 | 4 | Smr domain | |
| 1 | 1 | 2 | IPP transferase | |
| 2 | 1 | 3 | Cobalamin-independent synthase, Catalytic domain | |
| 1 | 3 | 4 | BolA-like protein | |
| 1 | 1 | 2 | Ham1 family | |
| 5 | 5 | 10 | FtsJ-like methyltransferase | |
| 1 | 1 | Quinolinate phosphoribosyl transferase, C-terminal domain | ||
| 7 | 7 | 14 | Nucleoside transporter | |
| 9 | 9 | 18 | Patatin-like phospholipase | |
| 1 | 1 | 2 | Dienelactone hydrolase family | |
| 18 | 16 | 34 | STAS domain | |
| 3 | 3 | Large-conductance mechanosensitive channel, MscL | ||
| 2 | 2 | 4 | Poly A polymerase head domain | |
| 1 | 1 | 2 | ATP-sulfurylase | |
| 2 | 2 | 4 | Importin beta binding domain | |
| 3 | 2 | 5 | Toprim domain | |
| 19 | 22 | 41 | MYND finger | |
| 2 | 1 | 3 | A20-like zinc finger | |
| 10 | 8 | 18 | Acyl-CoA oxidase | |
| 10 | 16 | 26 | Acyltransferase family | |
| 1 | 2 | 3 | Sodium Bile acid symporter family | |
| 1 | 1 | 2 | 3-dehydroquinate synthase | |
| 3 | 2 | 5 | Galactosyltransferase | |
| 7 | 8 | 15 | Lipase (class 3) | |
| 1 | 1 | 2 | Ribosome recycling factor | |
| 1 | 1 | 2 | UreD urease accessory protein | |
| 2 | 1 | 3 | Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A | |
| 1 | 1 | 2 | Ribosomal L22e protein family | |
| 1 | 1 | 2 | Ribosomal L27e protein family | |
| 1 | 1 | 2 | Ribosomal L28e protein family | |
| 1 | 1 | Ribosomal L29e protein family | ||
| 2 | 1 | 3 | Ribosomal L37ae protein family | |
| 1 | 1 | 2 | Ribosomal L38e protein family | |
| 4 | 4 | 8 | Alternative oxidase | |
| 1 | 1 | 2 | DeoC/LacD family aldolase | |
| 19 | 16 | 35 | Ferric reductase like transmembrane component | |
| 2 | 1 | 3 | MraW methylase family | |
| 4 | 3 | 7 | snoRNA binding domain, fibrillarin | |
| 1 | 1 | 2 | [2Fe-2S] binding domain | |
| 3 | 3 | 6 | Surp module | |
| 1 | 2 | 3 | AICARFT/IMPCHase bienzyme | |
| 1 | 1 | LysE type translocator | ||
| 1 | 1 | 2 | 5-formyltetrahydrofolate cyclo-ligase family | |
| 1 | 1 | 2 | ATP synthase subunit D | |
| 1 | 1 | 2 | Chorismate mutase type II | |
| 1 | 1 | GPCR proteolysis site, GPS, motif | ||
| 1 | 3 | 4 | IPT/TIG domain | |
| 2 | 2 | FG-GAP repeat | ||
| 1 | 1 | 2 | Transglutaminase-like superfamily | |
| 9 | 8 | 17 | ACT domain | |
| 2 | 1 | 3 | FF domain | |
| 2 | 2 | 4 | NAC domain | |
| 2 | 3 | 5 | Proteasome/cyclosome repeat | |
| 6 | 6 | 12 | START domain | |
| 1 | 1 | 2 | MOZ/SAS family | |
| 1 | 1 | 2 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg | |
| 1 | 1 | Retinoblastoma-associated protein B domain | ||
| 1 | 2 | 3 | Retinoblastoma-associated protein A domain | |
| 2 | 2 | 4 | Putative diphthamide synthesis protein | |
| 1 | 1 | Domain of unknown function UPF0086 | ||
| 1 | 1 | 2 | AMMECR1 | |
| 2 | 2 | 4 | Domain found in IF2B/IF5 | |
| 1 | 1 | 2 | Memo-like protein | |
| 1 | 1 | 2 | RNase P subunit p30 | |
| 2 | 2 | 4 | Iron-sulfur cluster assembly protein | |
| 1 | 1 | RNA 2'-phosphotransferase, Tpt1 / KptA family | ||
| 1 | 1 | 2 | Uncharacterised protein family UPF0047 | |
| 1 | 1 | 2 | DNA primase small subunit | |
| 1 | 1 | Rpp14/Pop5 family | ||
| 1 | 1 | 2 | Diphthamide synthase | |
| 1 | 1 | 2 | Putative heavy-metal-binding | |
| 1 | 1 | 2 | Ribosomal protein L37e | |
| 5 | 5 | 10 | Nucleotidyltransferase domain | |
| 1 | 1 | 2 | eIF-6 family | |
| 25 | 27 | 52 | Glycosyl hydrolase family 3 C-terminal domain | |
| 1 | 1 | 2 | Deoxyhypusine synthase | |
| 2 | 2 | 4 | Prefoldin subunit | |
| 2 | 2 | SRP19 protein | ||
| 1 | 1 | Cobalamin adenosyltransferase | ||
| 4 | 7 | 11 | Sulfite exporter TauE/SafE | |
| 9 | 9 | 18 | 50S ribosome-binding GTPase | |
| 1 | 1 | Mut7-C RNAse domain | ||
| 1 | 1 | Ribosomal protein L14 | ||
| 1 | 1 | Uncharacterised protein family UPF0052 | ||
| 5 | 4 | 9 | Protein of unknown function DUF89 | |
| 1 | 1 | TRAM domain | ||
| 1 | 1 | 2 | Integral membrane protein DUF92 | |
| 1 | 1 | 2 | ArgJ family | |
| 5 | 4 | 9 | DJ-1/PfpI family | |
| 4 | 4 | 8 | HD domain | |
| 1 | 1 | 2 | MoaC family | |
| 2 | 1 | 3 | Hydantoinase/oxoprolinase | |
| 2 | 1 | 3 | Protein of unknown function DUF111 | |
| 1 | 1 | 2 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase | |
| 8 | 7 | 15 | Amidohydrolase family | |
| 1 | 2 | 3 | tRNA-methyltransferase O | |
| 1 | 1 | 2 | Peptidyl-tRNA hydrolase PTH2 | |
| 1 | 1 | Double-stranded DNA-binding domain | ||
| 1 | 1 | 2 | Mitochondrial biogenesis AIM24 | |
| 1 | 1 | 2 | VIT family | |
| 1 | 1 | 2 | ATP synthase (F/14-kDa) subunit | |
| 1 | 1 | 2 | ATP synthase (E/31 kDa) subunit | |
| 1 | 1 | 2 | ATP synthase (C/AC39) subunit | |
| 1 | 1 | 2 | Translin family | |
| 1 | 1 | 2 | TFIIE alpha subunit | |
| 1 | 1 | 2 | N2,N2-dimethylguanosine tRNA methyltransferase | |
| 1 | 1 | 2 | LD-carboxypeptidase N-terminal domain | |
| 3 | 2 | 5 | eIF4-gamma/eIF5/eIF2-epsilon | |
| 3 | 3 | 6 | RyR domain | |
| 2 | 2 | 4 | SCP-2 sterol transfer family | |
| 7 | 6 | 13 | SAP domain | |
| 15 | 14 | 29 | RWP-RK domain | |
| 2 | 1 | 3 | CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B | |
| 10 | 12 | 22 | Glycosyl hydrolase family 30 TIM-barrel domain | |
| 1 | 1 | 2 | Palmitoyl protein thioesterase | |
| 2 | 2 | 4 | 60Kd inner membrane protein | |
| 1 | 1 | Josephin | ||
| 1 | 1 | SURF1 family | ||
| 1 | 1 | DAD family | ||
| 1 | 1 | 2 | Phosducin | |
| 1 | 1 | 2 | RHO protein GDP dissociation inhibitor | |
| 1 | 1 | 2 | Phosphatidylinositol transfer protein | |
| 1 | 1 | 2 | Aminopeptidase I zinc metalloprotease (M18) | |
| 1 | 2 | 3 | X-Pro dipeptidyl-peptidase (S15 family) | |
| 1 | 1 | Uncharacterized protein family UPF0054 | ||
| 2 | 2 | 4 | Permease for cytosine/purines, uracil, thiamine, allantoin | |
| 4 | 4 | 8 | ||
| 4 | 4 | 8 | TAZ zinc finger | |
| 2 | 1 | 3 | Nuclear transport factor 2 (NTF2) domain | |
| 10 | 8 | 18 | Beige/BEACH domain | |
| 3 | 4 | 7 | DENN (AEX-3) domain | |
| 3 | 3 | 6 | MGS-like domain | |
| 1 | 1 | 2 | Repair protein Rad1/Rec1/Rad17 | |
| 2 | 1 | 3 | Rap/ran-GAP | |
| 5 | 4 | 9 | Sir2 family | |
| 2 | 2 | 4 | Zn-finger in ubiquitin-hydrolases and other protein | |
| 1 | 2 | 3 | Kinase associated domain 1 | |
| 2 | 2 | 4 | RNA polymerases M/15 Kd subunit | |
| 1 | 1 | 2 | UvrB/uvrC motif | |
| 1 | 1 | 2 | Cytochrome C1 family | |
| 6 | 7 | 13 | PAZ domain | |
| 5 | 6 | 11 | Piwi domain | |
| 1 | 1 | 2 | TRAF-type zinc finger | |
| 1 | 2 | 3 | AT hook motif | |
| 8 | 8 | 16 | Formin Homology 2 Domain | |
| 2 | 2 | 4 | HAT (Half-A-TPR) repeat | |
| 3 | 2 | 5 | ATP-dependent protease La (LON) substrate-binding domain | |
| 1 | 1 | 2 | PXA domain | |
| 1 | 1 | ParB-like nuclease domain | ||
| 1 | 1 | Regulatory subunit of type II PKA R-subunit | ||
| 3 | 3 | 6 | SWIB/MDM2 domain | |
| 4 | 4 | 8 | Vacuolar sorting protein 9 (VPS9) domain | |
| 2 | 2 | 4 | WH2 motif | |
| 5 | 5 | 10 | Putative zinc finger in N-recognin (UBR box) | |
| 1 | 1 | 2 | Villin headpiece domain | |
| 3 | 4 | 7 | Dynamin GTPase effector domain | |
| 1 | 2 | 3 | GYF domain | |
| 2 | 3 | 5 | BTB/POZ domain | |
| 2 | 2 | 4 | Methylenetetrahydrofolate reductase | |
| 1 | 1 | 2 | ML domain | |
| 2 | 2 | 4 | ATP-grasp domain | |
| 1 | 1 | 2 | Thymidylate kinase | |
| 19 | 20 | 39 | PA domain | |
| 1 | 1 | 2 | Transcriptional Coactivator p15 (PC4) | |
| 3 | 3 | 6 | Phospholipase/Carboxylesterase | |
| 1 | 1 | 2 | ||
| 1 | 1 | 2 | Proteasome activator pa28 beta subunit | |
| 1 | 1 | 2 | Iron hydrogenase small subunit | |
| 3 | 2 | 5 | FAT domain | |
| 6 | 5 | 11 | FATC domain | |
| 6 | 6 | 12 | Guanylate-binding protein, N-terminal domain | |
| 1 | 1 | 2 | Transcription initiation factor IID, 18kD subunit | |
| 1 | 1 | 2 | Amidinotransferase | |
| 1 | 1 | 2 | Linear amide C-N hydrolases, choloylglycine hydrolase family | |
| 1 | 1 | 2 | Signal recognition particle 14kD protein | |
| 1 | 1 | 2 | Transcription initiation factor IID, 31kD subunit | |
| 2 | 2 | Cytochrome oxidase c subunit VIb | ||
| 1 | 2 | 3 | HORMA domain | |
| 2 | 2 | 4 | B12 binding domain | |
| 1 | 2 | 3 | E2F/DP family winged-helix DNA-binding domain | |
| 1 | 1 | Ubiquinol-cytochrome C reductase hinge protein | ||
| 1 | 1 | Mitochondrial glycoprotein | ||
| 6 | 5 | 11 | OTU-like cysteine protease | |
| 1 | 1 | 2 | Glycine cleavage system P-protein | |
| 1 | 1 | 2 | Cytidylyltransferase | |
| 1 | 2 | 3 | Mycolic acid cyclopropane synthetase | |
| 6 | 10 | 16 | Trehalose-phosphatase | |
| 2 | 1 | 3 | Cell division protein 48 (CDC48), N-terminal domain | |
| 7 | 7 | 14 | 1,3-beta-glucan synthase component | |
| 1 | 1 | 2 | Threonylcarbamoyl adenosine biosynthesis protein TsaE | |
| 9 | 9 | 18 | JmjC domain, hydroxylase | |
| 1 | 1 | 2 | Anion-transporting ATPase | |
| 2 | 2 | 4 | jmjN domain | |
| 3 | 3 | 6 | SacI homology domain | |
| 2 | 2 | 4 | Putative methyltransferase | |
| 1 | 1 | 2 | MoaE protein | |
| 1 | 1 | 2 | Seryl-tRNA synthetase N-terminal domain | |
| 4 | 4 | 8 | ||
| 1 | 1 | 2 | Ribosomal silencing factor during starvation | |
| 1 | 1 | Chromate transporter | ||
| 1 | 1 | 2 | Conserved carboxylase domain | |
| 1 | 1 | 2 | Quinolinate synthetase A protein | |
| 2 | 2 | 4 | Lecithin:cholesterol acyltransferase | |
| 5 | 4 | 9 | Transferase family | |
| 4 | 3 | 7 | Patched family | |
| 6 | 10 | 16 | RecF/RecN/SMC N terminal domain | |
| 7 | 4 | 11 | Tim17/Tim22/Tim23/Pmp24 family | |
| 2 | 2 | 4 | Met-10+ like-protein | |
| 6 | 5 | 11 | ||
| 1 | 1 | 2 | CLN3 protein | |
| 1 | 1 | 2 | ||
| 6 | 5 | 11 | CobW/HypB/UreG, nucleotide-binding domain | |
| 15 | 15 | 30 | MORN repeat | |
| 1 | 1 | 2 | CoA-transferase family III | |
| 2 | 2 | 4 | Oligosaccharyl transferase STT3 subunit | |
| 1 | 2 | 3 | CPBP intramembrane metalloprotease | |
| 15 | 14 | 29 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | |
| 24 | 22 | 46 | ZIP Zinc transporter | |
| 2 | 3 | 5 | mTERF | |
| 3 | 1 | 4 | CrcB-like protein, Camphor Resistance (CrcB) | |
| 2 | 1 | 3 | Hydantoinase B/oxoprolinase | |
| 1 | 1 | 2 | NAD synthase | |
| 3 | 1 | 4 | 3-oxo-5-alpha-steroid 4-dehydrogenase | |
| 1 | 1 | Maf-like protein | ||
| 2 | 2 | 4 | Ketopantoate hydroxymethyltransferase | |
| 2 | 1 | 3 | Phenazine biosynthesis-like protein | |
| 1 | 1 | 2 | Pantoate-beta-alanine ligase | |
| 4 | 3 | 7 | Homocysteine S-methyltransferase | |
| 1 | 1 | D-Tyr-tRNA(Tyr) deacylase | ||
| 2 | 2 | 4 | Uncharacterised ACR, YagE family COG1723 | |
| 1 | 1 | SOS response associated peptidase (SRAP) | ||
| 1 | 1 | 2 | Putative RNA methyltransferase | |
| 1 | 1 | 2 | Uroporphyrinogen-III synthase HemD | |
| 1 | 1 | 2 | B12 binding domain | |
| 1 | 2 | 3 | Cytochrome oxidase assembly protein | |
| 2 | 2 | 4 | CoA binding domain | |
| 1 | 1 | 2 | SCO1/SenC | |
| 3 | 2 | 5 | Putative S-adenosyl-L-methionine-dependent methyltransferase | |
| 1 | 1 | 2 | GatB domain | |
| 1 | 1 | 2 | Fic/DOC family | |
| 1 | 2 | 3 | Phosphatidylserine decarboxylase | |
| 6 | 5 | 11 | Taurine catabolism dioxygenase TauD, TfdA family | |
| 1 | 1 | 2 | Paired amphipathic helix repeat | |
| 1 | 1 | Methyltransferase TYW3 | ||
| 3 | 3 | 6 | Pirin | |
| 1 | 1 | Lipid-A-disaccharide synthetase | ||
| 4 | 4 | 8 | Glucokinase | |
| 7 | 5 | 12 | Na+/Pi-cotransporter | |
| 1 | 1 | 2 | Uncharacterized ACR, YdiU/UPF0061 family | |
| 1 | 1 | N-terminal domain of galactosyltransferase | ||
| 2 | 3 | 5 | Calcium-dependent channel, 7TM region, putative phosphate | |
| 5 | 4 | 9 | ||
| 1 | 1 | 2 | CDC45-like protein | |
| 4 | 6 | 10 | Copper amine oxidase, N2 domain | |
| 4 | 6 | 10 | Copper amine oxidase, N3 domain | |
| 2 |
