PFAM Domains • Scheffersomyces stipitis NRRL Y-11545 v2.0
Annotations/GenomesPicst3Sacce1TotalAnnotation Description
PFAMs
4,5715,53510,106
283361ATPase family associated with various cellular activities (AAA)
313162ABC transporter
448ATP synthase alpha/beta family, nucleotide-binding domain
141630Elongation factor Tu GTP binding domain
7714Helix-loop-helix DNA-binding domain
22Hsp20/alpha crystallin family
121426Hsp70 protein
8816KH domain
112SH2 domain
222244SH3 domain
8917Actin
141832Ankyrin repeat
7714ADP-ribosylation factor family
9716Eukaryotic aspartyl protease
437Cyclic nucleotide-binding domain
123Cytochrome c
123Double-stranded RNA binding motif
131124EF hand
1124Fe-4S binding domain
11Fibronectin type III domain
224Globin
268Glutathione S-transferase, C-terminal domain
437Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
3811Homeodomain
336lactate/malate dehydrogenase, NAD binding domain
358Myosin head (motor domain)
10313Cytochrome P450
95114209Protein kinase domain
8917Pyridine nucleotide-disulphide oxidoreductase
232447Ras family
6410Response regulator receiver domain
112RNase H
474895RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
11Retroviral aspartyl protease
314Copper/zinc superoxide dismutase (SODC)
213Iron/manganese superoxide dismutases, alpha-hairpin domain
448Subtilase family
603494Sugar (and other) transporter
91019Thioredoxin
11Trypsin
347Tubulin/FtsZ family, GTPase domain
493887Zinc finger, C2H2 type
242246Zinc finger, C3HC4 type (RING finger)
5611Zinc knuckle
235Protein-tyrosine phosphatase
311344short chain dehydrogenase
241741Zinc-binding dehydrogenase
426Thiolase, N-terminal domain
224Beta-ketoacyl synthase, N-terminal domain
3252Fe-2S iron-sulfur cluster binding domain
156Enolase, C-terminal TIM barrel domain
7916Glutamine amidotransferase class-I
101020TCP-1/cpn60 chaperonin family
112Glutamine synthetase, catalytic domain
112Triosephosphate isomerase
111223E1-E2 ATPase
111021Core histone H2A/H2B/H3/H4
6814Alpha amylase, catalytic domain
112Phorbol esters/diacylglycerol binding domain (C1 domain)
549Bacterial transferase hexapeptide (six repeats)
7310tRNA synthetases class I (I, L, M and V)
111324Cyclin, N-terminal domain
448DNA polymerase family B
336ATP synthase subunit C
213Peroxidase
22Beta-lactamase
182139Calcineurin-like phosphoesterase
448Cellulase (glycosyl hydrolase family 5)
6612tRNA synthetases class II (D, K and N)
343468Mitochondrial carrier protein
101121Aminotransferase class I and II
81119Phosphoribosyl transferase domain
8816Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
112Phosphoglycerate kinase
235Ribosomal protein S4/S9 N-terminal domain
235Ribosomal protein S12/S23
112Chaperonin 10 Kd subunit
91120C2 domain
152439PH domain
5813bZIP transcription factor
10919Aldehyde dehydrogenase family
8553138Fungal Zn(2)-Cys(6) binuclear cluster domain
14721Cytochrome b5-like Heme/Steroid binding domain
7815Oxidoreductase NAD-binding domain
181735SNF2 family N-terminal domain
224Ribosomal protein S7p/S5e
131427Ubiquitin-conjugating enzyme
6713Isocitrate/isopropylmalate dehydrogenase
336Ribosomal Proteins L2, RNA binding domain
123Hsp90 protein
224Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
336Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
2242-oxoacid dehydrogenases acyltransferase (catalytic domain)
123Catalase
7411Aminotransferase class-III
224Ribosomal protein S19
112DNA gyrase B
3710Thiamine pyrophosphate enzyme, central domain
437Lyase
235Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
112Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
112Indole-3-glycerol phosphate synthase
11Neurohypophysial hormones, N-terminal Domain
123Pyruvate kinase, barrel domain
6612Kinesin motor domain
242145DnaJ domain
141428Proteasome subunit
145Major intrinsic protein
112ATP synthase
1123'5'-cyclic nucleotide phosphodiesterase
112Profilin
123Ribosomal protein L22p/L17e
235Ribosomal protein L14p/L23e
6915Ubiquitin family
336Cofilin/tropomyosin-type actin-binding protein
12314-3-3 protein
213Alkaline phosphatase
112Zinc carboxypeptidase
171633Aldo/keto reductase family
121527Myb-like DNA-binding domain
347Forkhead domain
11Glycosyl hydrolases family 32 N-terminal domain
112Ribosomal protein L16p/L10e
134Ribosomal protein S14p/S29e
347FKBP-type peptidyl-prolyl cis-trans isomerase
235Glutathione peroxidase
123
8715Flavodoxin
112Calreticulin family
336Aminotransferase class-V
123Ribonucleotide reductase, small chain
375693DEAD/DEAH box helicase
5679135Helicase conserved C-terminal domain
112EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
224Ribosomal protein L23
112Pyridoxal-dependent decarboxylase, C-terminal sheet domain
134Ribosomal protein L5
325Pyridoxal-dependent decarboxylase conserved domain
134Citrate synthase, C-terminal domain
4610GHMP kinases N terminal domain
5712Biotin carboxylase, N-terminal domain
112Tryptophan synthase alpha chain
8715Pyridoxal-phosphate dependent enzyme
8715NUDIX domain
246pfkB family carbohydrate kinase
11Glycosyl hydrolases family 28
224Ribosomal protein L3
235Ribosomal protein L11, RNA binding domain
81220Histidine phosphatase superfamily (branch 1)
112Thymidylate synthase
448ATP synthase alpha/beta chain, C terminal domain
549Calponin homology (CH) domain
4711Glutamine amidotransferases class-II
224Ribosomal protein S15
112Fructose-1-6-bisphosphatase, N-terminal domain
224Ribonucleotide reductase, all-alpha domain
235Ribosomal protein S2
246SRF-type transcription factor (DNA-binding and dimerisation domain)
91019GATA zinc finger
362460Amino acid permease
224Prolyl oligopeptidase family
246Ribosomal protein L30p/L7e
369Histidine phosphatase superfamily (branch 2)
11Respiratory-chain NADH dehydrogenase, 30 Kd subunit
549Aconitase family (aconitate hydratase)
11Glycosyl hydrolase family 10
235Glycosyl hydrolases family 17
224Ribosomal protein S5, N-terminal domain
112Nucleoside diphosphate kinase
123Ribosomal protein S10p/S20e
235Arrestin (or S-antigen), N-terminal domain
112Phosphoglucose isomerase
112Carbohydrate phosphorylase
224SecY translocase
11Respiratory-chain NADH dehydrogenase, 49 Kd subunit
235Ribosomal protein L6
336Polyprenyl synthetase
358Hexokinase
336Dynamin family
112Transcription factor TFIID (or TATA-binding protein, TBP)
213Rieske [2Fe-2S] domain
6814Biotin-requiring enzyme
224Phosphofructokinase
235Ribosomal protein S17
123Hydroxymethylglutaryl-coenzyme A reductase
336FGGY family of carbohydrate kinases, N-terminal domain
336Enoyl-CoA hydratase/isomerase
235Ribosomal protein S9/S16
235Transcription factor TFIIB repeat
6612Cytidine and deoxycytidylate deaminase zinc-binding region
11Molybdopterin oxidoreductase
123Chromo (CHRromatin Organisation MOdifier) domain
112Phosphatidylinositol-specific phospholipase C, Y domain
213Phosphatidylinositol-specific phospholipase C, X domain
448D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
112Malic enzyme, N-terminal domain
1236-phosphogluconate dehydrogenase, C-terminal domain
235Multicopper oxidase
7512WW domain
224Ribosomal RNA adenine dimethylase
1010Yeast PIR protein repeat
8488172WD domain, G-beta repeat
538Heavy-metal-associated domain
336Adenylate kinase
235Phosphoglucomutase/phosphomannomutase, C-terminal domain
224Ribosomal protein S8
123Ribosomal protein S11
347LIM domain
112Regulator of chromosome condensation (RCC1) repeat
235Ribosomal protein S13/S18
224chorismate binding enzyme
551060s Acidic ribosomal protein
448Prenyltransferase and squalene oxidase repeat
4812Protein kinase C terminal domain
112Single-strand binding protein family
123S-adenosylmethionine synthetase, N-terminal domain
91019Bromodomain
33Acyl-CoA dehydrogenase, C-terminal domain
161632Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
213Ribonuclease T2 family
459HSF-type DNA-binding
224SRP54-type protein, GTPase domain
437Serine carboxypeptidase
8917Phosphatidylinositol 3- and 4-kinase
224Transketolase, thiamine diphosphate binding domain
134Inositol monophosphatase family
4711Glutaredoxin
123Isocitrate lyase family
224Serine hydroxymethyltransferase
11Iron-containing alcohol dehydrogenase
224Ribosomal protein L10
6713KOW motif
112Ribosomal protein L34
325RF-1 domain
617Sodium:solute symporter family
11Imidazoleglycerol-phosphate dehydratase
112DNA polymerase family A
156IMP dehydrogenase / GMP reductase domain
112Glucose-6-phosphate dehydrogenase, NAD binding domain
6713Protein phosphatase 2C
224Nucleotidyl transferase
213Carbonic anhydrase
224Phosphoribulokinase / Uridine kinase family
617Fatty acid desaturase
4610MutS domain V
112Delta-aminolevulinic acid dehydratase
314Arginase family
6612MCM P-loop domain
112Squalene/phytoene synthase
61420FHA domain
101020AMP-binding enzyme
224G-protein alpha subunit
5712HMG (high mobility group) box
213His Kinase A (phospho-acceptor) domain
224Armadillo/beta-catenin-like repeat
142135Tetratricopeptide repeat
325Ion transport protein
112DNA gyrase/topoisomerase IV, subunit A
91019BRCA1 C Terminus (BRCT) domain
448Glycosyl transferases group 1
224Glycosyl transferase family 2
11SAM domain (Sterile alpha motif)
112linker histone H1 and H5 family
112Ribosomal protein L7/L12 C-terminal domain
224CoA-ligase
325Phosphopantetheine attachment site
224Formyl transferase
6612Metallopeptidase family M24
291140Leucine Rich Repeat
191534alpha/beta hydrolase fold
336RNA polymerase Rpb2, domain 6
213PB1 domain
213Staphylococcal nuclease homologue
8816Rab-GTPase-TBC domain
11Tudor domain
112WH1 domain
224Zinc finger, ZZ type
123HRDC domain
71017CBS domain
235Ribosomal protein L13
134Ribosomal protein L4/L1 family
246S1 RNA binding domain
11HIUase/Transthyretin family
6410AhpC/TSA family
448tRNA synthetases class I (W and Y)
235UvrD/REP helicase N-terminal domain
4913Rhodanese-like domain
11Universal stress protein family
131326Acetyltransferase (GNAT) family
112SecE/Sec61-gamma subunits of protein translocation complex
112C-terminal regulatory domain of Threonine dehydratase
224AIR synthase related protein, N-terminal domain
8917tRNA synthetase class II core domain (G, H, P, S and T)
224SpoU rRNA Methylase family
224Tetrapyrrole (Corrin/Porphyrin) Methylases
112Glycosyl transferase family, a/b domain
123PDZ domain
213Class II Aldolase and Adducin N-terminal domain
358Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
448Fes/CIP4, and EFC/F-BAR homology domain
336IQ calmodulin-binding motif
224Phosphoinositide 3-kinase family, accessory domain (PIK domain)
224Phospholipase D Active site motif
11Regulator of G protein signaling domain
347GTPase-activator protein for Ras-like GTPase
448RasGEF domain
145RasGEF N-terminal motif
81119RhoGAP domain
235RhoGEF domain
336SPRY domain
336RNA polymerase Rpb1, domain 2
44Flocculin repeat
112Guanylate kinase
347Gelsolin repeat
4913UBA/TS-N domain
141327PHD-finger
11GGL domain
5510HECT-domain (ubiquitin-transferase)
11Helix-hairpin-helix motif
123MSP (Major sperm protein) domain
235Ribonuclease III domain
235Region in Clathrin and VPS
336RanBP1 domain
213PPIC-type PPIASE domain
112Zn-finger in Ran binding protein and others
7714Zinc finger C-x8-C-x5-C-x3-H type (and similar)
151227F-box domain
123Elongation factor 1 gamma, conserved domain
235Copper fist DNA binding domain
5611CRAL/TRIO domain
11BTB/POZ domain
112Inhibitor of Apoptosis domain
314Voltage gated chloride channel
213Caspase domain
213GDSL-like Lipase/Acylhydrolase
112Poly-adenylate binding protein, unique domain
112POLO box duplicated region
3131Seripauperin and TIP1 family
141024ABC transporter transmembrane region
22Integrase core domain
336FAD binding domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
11HAMP domain
235ribosomal L5P family C-terminus
2323DUP family
7714Insulinase (Peptidase family M16)
224Dehydrogenase E1 component
112Lumazine binding domain
6713Elongation factor G C-terminus
5611HMGL-like
5510DnaJ central domain
235Ribosomal protein L1p/L10e family
5510Cation transporting ATPase, C-terminus
4711Cation transporter/ATPase, N-terminus
112dUTPase
549Aconitase C-terminal domain
347Amino acid kinase family
112N-(5'phosphoribosyl)anthranilate (PRA) isomerase
213Acyl transferase domain
33Dihydrodipicolinate synthetase family
182543haloacid dehalogenase-like hydrolase
33Glycosyl hydrolases family 2
426Glycosyl hydrolases family 18
112Proliferating cell nuclear antigen, N-terminal domain
112Adenylosuccinate synthetase
156Asparaginase, N-terminal
134Peptidase S24-like
224Inorganic pyrophosphatase
336Glycosyl hydrolases family 16
112Glycosyl hydrolases family 15
13215NADH:flavin oxidoreductase / NADH oxidase family
11Glycosyl hydrolase family 20, catalytic domain
347HhH-GPD superfamily base excision DNA repair protein
112AIR carboxylase
22GMC oxidoreductase
134Asparagine synthase
7714Septin
112EF-1 guanine nucleotide exchange domain
112Homoserine dehydrogenase
336tRNA synthetases class I (E and Q), catalytic domain
123tRNA synthetases class I (R)
358XPG N-terminal domain
246Metallo-beta-lactamase superfamily
336Choline/Carnitine o-acyltransferase
112Putative esterase
112Ferrochelatase
336Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
336RNB domain
22Dioxygenase
235CNH domain
123Diacylglycerol kinase catalytic domain
5611Dual specificity phosphatase, catalytic domain
156P21-Rho-binding domain
131427PX domain
224Ras association (RalGDS/AF-6) domain
5712UBX domain
347VHS domain
112Phosphoinositide 3-kinase C2
224DAHP synthetase I family
7512Carbon-nitrogen hydrolase
112Prephenate dehydratase
358Syntaxin
6713Pumilio-family RNA binding repeat
549Histone-like transcription factor (CBF/NF-Y) and archaeal histone
112Pterin binding enzyme
112ER lumen protein retaining receptor
224Glycoprotease family
112Histidinol dehydrogenase
224impB/mucB/samB family
112
123Ribosomal L15
123Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
11Ribosomal prokaryotic L21 protein
112Ribosomal L28 family
123Ribosomal L29 protein
112Ribosomal L39 protein
123Ribosomal S17
112Ribulose-phosphate 3 epimerase family
112Translationally controlled tumour protein
347RNA pseudouridylate synthase
6511Histone deacetylase domain
415POT family
224PWWP domain
5813SET domain
112Isochorismatase family
11Permease family
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
459XPG I-region
11DNA photolyase
11Sulfatase
1126,7-dimethyl-8-ribityllumazine synthase
112Ribosomal protein S16
213Acyl CoA binding protein
347Cullin family
347FAD binding domain
134EamA-like transporter family
123
8816ThiF family
224Ribosomal family S4e
213Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
336Ammonium Transporter Family
448Sulfate permease family
112MATH domain
112Dehydratase family
123Transaldolase/Fructose-6-phosphate aldolase
112GTP cyclohydrolase II
1123,4-dihydroxy-2-butanone 4-phosphate synthase
347Adaptor complexes medium subunit family
5510Exonuclease
224Dipeptidyl peptidase IV (DPP IV) N-terminal region
88Glycosyl hydrolase family 3 N terminal domain
123Ribosomal protein L44
22Sodium:sulfate symporter transmembrane region
213DNA-dependent RNA polymerase
112Glycosyl transferase family 4
112HCO3- transporter family
224Nucleosome assembly protein (NAP)
459Synaptobrevin
112GMP synthase C terminal domain
246Adenosine/AMP deaminase
4610Oxidoreductase FAD-binding domain
224Histidine biosynthesis protein
347Glycosyltransferase family 20
224Carbamoyl-phosphate synthase small chain, CPSase domain
11PAS fold
11
112Probable molybdopterin binding domain
448Sec1 family
224GDP dissociation inhibitor
235Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
448Initiation factor 2 subunit family
123Electron transfer flavoprotein domain
11Uricase
224Ribosomal S3Ae family
112Ribosomal L27 protein
314GTP1/OBG
213Gamma-glutamyltranspeptidase
22Ribosomal L40e family
112GrpE
224TatD related DNase
112Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
22Receptor L domain
224Dynamin central region
2136-O-methylguanine DNA methyltransferase, DNA binding domain
134Bacteriorhodopsin-like protein
123Carboxyl transferase domain
224UbiA prenyltransferase family
235Endoribonuclease L-PSP
5813Cys/Met metabolism PLP-dependent enzyme
314Glycosyl hydrolases family 31
11NADH ubiquinone oxidoreductase, 20 Kd subunit
1010ABC-2 type transporter
224Amino-transferase class IV
459CDP-alcohol phosphatidyltransferase
224ATP dependent DNA ligase domain
213FMN-dependent dehydrogenase
112Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
1123-beta hydroxysteroid dehydrogenase/isomerase family
112Glycosyl hydrolases family 38 N-terminal domain
112Nitrite and sulphite reductase 4Fe-4S domain
112Ribosomal protein S18
112Clathrin light chain
112Galactose-1-phosphate uridyl transferase, N-terminal domain
213Ubiquitin carboxyl-terminal hydrolase, family 1
11
123Ribosomal protein S19e
123Ribosomal protein S6e
448Transcription factor S-II (TFIIS)
112Surface antigen
5712emp24/gp25L/p24 family/GOLD
213NifU-like domain
112Cyclin-dependent kinase regulatory subunit
11Dihydrodipicolinate reductase, N-terminus
112F-actin capping protein, beta subunit
112Fructose-bisphosphate aldolase class-II
224Semialdehyde dehydrogenase, NAD binding domain
246DNA mismatch repair protein, C-terminal domain
112Dephospho-CoA kinase
112G10 protein
112Heme oxygenase
123Succinate dehydrogenase/Fumarate reductase transmembrane subunit
112DNA topoisomerase
112Glucose inhibited division protein A
112RNA 3'-terminal phosphate cyclase
66123' exoribonuclease family, domain 1
112tRNA pseudouridine synthase D (TruD)
11Coenzyme A transferase
426SPFH domain / Band 7 family
235Cytidylyltransferase family
11Formamidopyrimidine-DNA glycosylase N-terminal domain
325GDA1/CD39 (nucleoside phosphatase) family
336GNS1/SUR4 family
112Hydroxymethylglutaryl-coenzyme A synthase N terminal
213Inosine-uridine preferring nucleoside hydrolase
224Ribosomal protein L21e
123Ribosomal protein L36e
123Ribosomal protein L6e
336Phosphatidylethanolamine-binding protein
112
224RIO1 family
224Alanine racemase, N-terminal domain
112Uncharacterized protein family UPF0016
112Putative RNA methylase family UPF0020
213PP-loop family
112Shwachman-Bodian-Diamond syndrome (SBDS) protein
134SNO glutamine amidotransferase family
112Translation initiation factor 1A / IF-1
11Asp/Glu/Hydantoin racemase
22Copper amine oxidase, enzyme domain
112Dihydroorotate dehydrogenase
123Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
7310GPR1/FUN34/yaaH family
11
33616S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
448RNA polymerase Rpb3/Rpb11 dimerisation domain
112RNA polymerases N / 8 kDa subunit
112Peptidyl-tRNA hydrolase
112Ribosomal protein L17
123Ribosomal protein L31e
123Ribosomal protein L34e
224Ribosomal protein S28e
235Ribosomal protein S8e
112Shikimate kinase
123Trehalase
224Uncharacterized protein family UPF0029
448Dihydrouridine synthase (Dus)
112Uroporphyrinogen decarboxylase (URO-D)
112ubiE/COQ5 methyltransferase family
224NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
11Beta-eliminating lyase
112Adenylate cyclase associated (CAP) N terminal
224Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
4610Clathrin adaptor complex small chain
112Coproporphyrinogen III oxidase
11Dehydroquinase class II
112Dynein light chain type 1
224Ergosterol biosynthesis ERG4/ERG24 family
112DNA/RNA non-specific endonuclease
112Formate/nitrite transporter
112GTP cyclohydrolase I
235HIT domain
112Indoleamine 2,3-dioxygenase
22Mannitol dehydrogenase Rossmann domain
112Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
4711Oxysterol-binding protein
112Phosphomannose isomerase type I
224Protein prenyltransferase alpha subunit repeat
336Pyridoxamine 5'-phosphate oxidase
235Ribosomal protein L24e
123Ribosomal protein L35Ae
6612Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
123Ribosomal protein S21e
123Ribosomal protein S7e
336Translation initiation factor SUI1
224Putative undecaprenyl diphosphate synthase
112Carbohydrate kinase
11Thioredoxin-like [2Fe-2S] ferredoxin
112SAICAR synthetase
112Xylose isomerase-like TIM barrel
112Alanine dehydrogenase/PNT, C-terminal domain
246Aldose 1-epimerase
112Chorismate synthase
224Cytochrome c/c1 heme lyase
7512FAD dependent oxidoreductase
112F-actin capping protein alpha subunit
224Formate--tetrahydrofolate ligase
112Fibrillarin
224Malate synthase
123Ribosomal protein L19e
123Ribosomal protein S24e
123Ribosomal protein S26e
11TEA/ATTS domain
123Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1127,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
112Phosphoenolpyruvate carboxykinase
123Ribosomal protein L13e
112Telomere recombination
347CAP-Gly domain
112
112Pterin 4 alpha carbinolamine dehydratase
112mRNA capping enzyme, catalytic domain
6814OB-fold nucleic acid binding domain
369Kelch motif
112Ribonuclease HII
99
5510FYVE zinc finger
11DHH family
358Sec7 domain
268NAD dependent epimerase/dehydratase family
112Porphobilinogen deaminase, dipyromethane cofactor binding domain
224SIS domain
112Helix-turn-helix
112Phosphate transporter family
123ARID/BRIGHT DNA binding domain
112Clathrin propeller repeat
7411JAB1/Mov34/MPN/PAD-1 ubiquitin protease
9817PCI domain
112tRNA synthetases class I (C) catalytic domain
426Oxidoreductase family, NAD-binding Rossmann fold
224tRNA synthetases class II core domain (F)
112tRNA synthetases class II (A)
5611Putative GTPase activating protein for Arf
235tRNA pseudouridine synthase
459ENTH domain
112NF-X1 type zinc finger
121628LSM domain
22R3H domain
9312Amidase
358BAH domain
123AN1-like Zinc finger
325Peptidase family M3
6410Peptidase family M1 domain
336Peptidase family M41
426Peptidase family M48
112Acetohydroxy acid isomeroreductase, catalytic domain
112Low molecular weight phosphotyrosine protein phosphatase
11MAGE family
235Eukaryotic porin
11GRIP domain
112Skp1 family, dimerisation domain
4610Cytidylyltransferase-like
347PUA domain
6612S4 domain
11PWI domain
112Proprotein convertase P-domain
123IBR domain, a half RING-finger domain
112Type I 3-dehydroquinase
314Shikimate / quinate 5-dehydrogenase
8715Transmembrane amino acid transporter protein
112Frataxin-like domain
112GXGXG motif
112FAD binding domain
224V-type ATPase 116kDa subunit family
224Glycosyl transferase family 8
112Phosphoribosyl-AMP cyclohydrolase
112Phosphoribosyl-ATP pyrophosphohydrolase
224Phosphatidylinositol-4-phosphate 5-Kinase
224Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
11Respiratory-chain NADH dehydrogenase 51 Kd subunit
235ATP-NAD kinase
224Iron-sulphur cluster biosynthesis
224Polysaccharide deacetylase
5712DHHC palmitoyltransferase
235Glycosyl hydrolase family 47
224PPR repeat
112Adenosylmethionine decarboxylase
112GIY-YIG catalytic domain
459CorA-like Mg2+ transporter protein
5510Cation efflux family
639Peptidase family M20/M25/M40
5611Acyltransferase
426MatE
459DnaJ C terminal domain
314Fumarylacetoacetate (FAA) hydrolase family
224Spermine/spermidine synthase domain
549FAD binding domain
336Natural resistance-associated macrophage protein
10717PAP2 superfamily
213Aminomethyltransferase folate-binding domain
224MaoC like domain
11Domain of unknown function (DUF19)
112Adenylylsulphate kinase
246G-patch domain
213Putative tRNA binding domain
112GAF domain
4486-phosphofructo-2-kinase
123NifU-like N terminal domain
213Flavin containing amine oxidoreductase
112Cyclin M transmembrane N-terminal domain
11O-methyltransferase
112Glycine cleavage H-protein
437
112Ribosomal protein S27a
8816Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
112I/LWEQ domain
1123'-5' exonuclease
112Proline dehydrogenase
347MutS domain I
112Peptide methionine sulfoxide reductase
112Hpt domain
112Ribosomal protein L35
224Choline/ethanolamine kinase
112ATP phosphoribosyltransferase
11Phosphotransferase enzyme family
112SelR domain
426Chitin synthase
112Conserved region in glutamate synthase
3364'-phosphopantetheinyl transferase superfamily
112Peptidase C13 family
213Eukaryotic initiation factor 4E
112Ribosomal protein L32
112Myo-inositol-1-phosphate synthase
112Macro domain
235Type I phosphodiesterase / nucleotide pyrophosphatase
224Ribosomal protein S27
347Proteolipid membrane potential modulator
134SOR/SNZ family
112Riboflavin kinase
325Rhomboid family
448Sodium/calcium exchanger protein
235UTP--glucose-1-phosphate uridylyltransferase
112Transcriptional regulator
213Smr domain
112IPP transferase
112Cobalamin-independent synthase, Catalytic domain
336BolA-like protein
112Ham1 family
437FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
112Nucleoside transporter
448Patatin-like phospholipase
549Lysophospholipase catalytic domain
325Dienelactone hydrolase family
448STAS domain
112Poly A polymerase head domain
11tRNA (Guanine-1)-methyltransferase
112ATP-sulfurylase
112Importin beta binding domain
112Toprim domain
112MYND finger
213Acyl-CoA oxidase
123Sodium Bile acid symporter family
1123-dehydroquinate synthase
224Lipase (class 3)
112Ribosome recycling factor
11Na+ dependent nucleoside transporter N-terminus
123Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
123Ribosomal L22e protein family
123Ribosomal L27e protein family
112Ribosomal L29e protein family
123Ribosomal L37ae protein family
112Ribosomal L38e protein family
112Ribosomal L32p protein family
112NIF3 (NGG1p interacting factor 3)
11Alternative oxidase
6915Glycolipid 2-alpha-mannosyltransferase
9918Ferric reductase like transmembrane component
336snoRNA binding domain, fibrillarin
112Surp module
123AICARFT/IMPCHase bienzyme
1125-formyltetrahydrofolate cyclo-ligase family
112ATP synthase subunit D
112Chorismate mutase type II
246WSC domain
123IPT/TIG domain
112Transglutaminase-like superfamily
448ACT domain
224DIL domain
123FF domain
235NAC domain
325Proteasome/cyclosome repeat
336MOZ/SAS family
224Putative diphthamide synthesis protein
112AMMECR1
112RibD C-terminal domain
224Domain found in IF2B/IF5
112Memo-like protein
112RNase P subunit p30
112Iron-sulfur cluster assembly protein
112RNA 2'-phosphotransferase, Tpt1 / KptA family
11Uncharacterised protein family UPF0047
112DNA primase small subunit
112Rpp14/Pop5 family
112Diphthamide synthase
123Ribosomal protein L37e
235Nucleotidyltransferase domain
112Thiamine-binding protein
112eIF-6 family
77Glycosyl hydrolase family 3 C-terminal domain
112Deoxyhypusine synthase
246Prefoldin subunit
112SRP19 protein
5121750S ribosome-binding GTPase
123Ribosomal protein L14
112Uncharacterised protein family UPF0052
112Protein of unknown function DUF89
112TRAM domain
112Thi4 family
112ArgJ family
145DJ-1/PfpI family
246HD domain
415Hydantoinase/oxoprolinase
224tRNA intron endonuclease, catalytic C-terminal domain
314Survival protein SurE
113-octaprenyl-4-hydroxybenzoate carboxy-lyase
437Amidohydrolase family
112Peptidyl-tRNA hydrolase PTH2
112Double-stranded DNA-binding domain
112VIT family
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
11Translin family
112TFIIE alpha subunit
112N2,N2-dimethylguanosine tRNA methyltransferase
178BNR/Asp-box repeat
224eIF4-gamma/eIF5/eIF2-epsilon
11SCP-2 sterol transfer family
358SAP domain
112CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
112Cytochrome c oxidase subunit VIa
112MAS20 protein import receptor
112Aromatic-di-Alanine (AdAR) repeat
112Pheromone A receptor
112SURF4 family
11Palmitoyl protein thioesterase
22460Kd inner membrane protein
112SURF1 family
112DAD family
112Hydroxyethylthiazole kinase family
112cAMP phosphodiesterases class-II
112RHO protein GDP dissociation inhibitor
112Fungal pheromone mating factor STE2 GPCR
325Aminopeptidase I zinc metalloprotease (M18)
11X-Pro dipeptidyl-peptidase (S15 family)
81018Permease for cytosine/purines, uracil, thiamine, allantoin
336
224Nuclear transport factor 2 (NTF2) domain
11Adenosine-deaminase (editase) domain
112Beige/BEACH domain
235MGS-like domain
11Repair protein Rad1/Rec1/Rad17
11Rap/ran-GAP
5510Sir2 family
336Zn-finger in ubiquitin-hydrolases and other protein
123Kinase associated domain 1
336RNA polymerases M/15 Kd subunit
112Dihydroneopterin aldolase
11XYPPX repeat (two copies)
112Cytochrome C1 family
268AT hook motif
112BAG domain
224Formin Homology 2 Domain
213HAT (Half-A-TPR) repeat
112Hr1 repeat
112TFIIE beta subunit core domain
112ATP-dependent protease La (LON) substrate-binding domain
112PXA domain
11ParB-like nuclease domain
112Regulatory subunit of type II PKA R-subunit
112STE like transcription factor
336SWIB/MDM2 domain
123Vacuolar sorting protein 9 (VPS9) domain
325WH2 motif
325Putative zinc finger in N-recognin (UBR box)
224Dynamin GTPase effector domain
235GYF domain
224Methylenetetrahydrofolate reductase
112ML domain
213ATP-grasp domain
112Thymidylate kinase
448PA domain
112Transcriptional Coactivator p15 (PC4)
112Phospholipase/Carboxylesterase
112Biotin protein ligase C terminal domain
112RFX DNA-binding domain
437FAT domain
459FATC domain
112Transcription initiation factor IIA, gamma subunit, helical domain
224Transcription initiation factor IID, 18kD subunit
112TFIIF, beta subunit HTH domain
112Ubiquinol-cytochrome C reductase complex 14kD subunit
112DHHA1 domain
112Cytochrome c oxidase subunit Va
11Signal recognition particle 14kD protein
112Transcription initiation factor IID, 31kD subunit
448
112Cytochrome oxidase c subunit VIb
235HORMA domain
11Ubiquinol-cytochrome C reductase hinge protein
112Mitochondrial glycoprotein
224OTU-like cysteine protease
112Glycine cleavage system P-protein
11Mycolic acid cyclopropane synthetase
134Trehalose-phosphatase
224Cell division protein 48 (CDC48), N-terminal domain
3361,3-beta-glucan synthase component
5611Dolichyl-phosphate-mannose-protein mannosyltransferase
549JmjC domain, hydroxylase
112Anion-transporting ATPase
235jmjN domain
459SacI homology domain
123Cation transport protein
112Putative methyltransferase
213Seryl-tRNA synthetase N-terminal domain
112Ornithine cyclodeaminase/mu-crystallin family
123Conserved carboxylase domain
347Flavoprotein
112Lecithin:cholesterol acyltransferase
123Reticulon
11Transferase family
112Patched family
5712RecF/RecN/SMC N terminal domain
11Competence-damaged protein
336Tim17/Tim22/Tim23/Pmp24 family
112Fasciclin domain
123Met-10+ like-protein
33
112CLN3 protein
11
112CobW/HypB/UreG, nucleotide-binding domain
11Ribose/Galactose Isomerase
11CoA-transferase family III
112Oligosaccharyl transferase STT3 subunit
11CPBP intramembrane metalloprotease
10919Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
11KID repeat
5510ZIP Zinc transporter
123CrcB-like protein, Camphor Resistance (CrcB)
314Hydantoinase B/oxoprolinase
112NAD synthase
11Ppx/GppA phosphatase family
1233-oxo-5-alpha-steroid 4-dehydrogenase
112Maf-like protein
112Ketopantoate hydroxymethyltransferase
112Acetyl-CoA hydrolase/transferase N-terminal domain
213Acyl-CoA thioesterase
325Ketopantoate reductase PanE/ApbA
112Phenazine biosynthesis-like protein
112Pantoate-beta-alanine ligase
134Homocysteine S-methyltransferase
112D-Tyr-tRNA(Tyr) deacylase
112Thiamine monophosphate synthase
336Uncharacterised ACR, YagE family COG1723
11GlcNAc-PI de-N-acetylase
112SOS response associated peptidase (SRAP)
123Putative RNA methyltransferase
112Uroporphyrinogen-III synthase HemD
11ATP-dependent Clp protease adaptor protein ClpS
112Carboxyltransferase domain, subdomain A and B
11Carboxymuconolactone decarboxylase family
112Cytochrome oxidase assembly protein
112CoA binding domain
123SCO1/SenC
112Putative S-adenosyl-L-methionine-dependent methyltransferase
123GatB domain
22Domain of unknown function (DUF202)
224Phosphatidylserine decarboxylase
9211Taurine catabolism dioxygenase TauD, TfdA family
112Paired amphipathic helix repeat
112Methyltransferase TYW3
11Pirin
11Carboxyltransferase domain, subdomain C and D
112Uncharacterized ACR, YdiU/UPF0061 family
11K+ potassium transporter
549Calcium-dependent channel, 7TM region, putative phosphate
112CDC45-like protein
22Copper amine oxidase, N2 domain
11Copper amine oxidase, N3 domain
224Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
112SKIP/SNW domain
224ERCC4 domain
325Dak1 domain
325DAK2 domain
224Ku70/Ku80 beta-barrel domain
224Myosin N-terminal SH3-like domain
112Galactose-1-phosphate uridyl transferase, C-terminal domain
11Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
112Proliferating cell nuclear antigen, C-terminal domain
112Quinolinate phosphoribosyl transferase, N-terminal domain
112Transcription initiation factor IIA, gamma subunit
448Arrestin (or S-antigen), C-terminal domain
224AIR synthase related protein, C-terminal domain
11Acyl-CoA dehydrogenase, middle domain
123S-adenosylmethionine synthetase, central domain
123S-adenosylmethionine synthetase, C-terminal domain
224Semialdehyde dehydrogenase, dimerisation domain
77Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
4711Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
415Iron/manganese superoxide dismutases, C-terminal domain
448Transketolase, pyrimidine binding domain
336Transketolase, C-terminal domain
112Glucose-6-phosphate dehydrogenase, C-terminal domain
134FGGY family of carbohydrate kinases, C-terminal domain
112Pyridoxal-dependent decarboxylase, pyridoxal binding domain
358Biotin carboxylase C-terminal domain
5712Carbamoyl-phosphate synthase L chain, ATP binding domain
224Carbamoyl-phosphate synthetase large chain, oligomerisation domain
22DDT domain
459Glutathione S-transferase, N-terminal domain
112Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
336Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
224Beta-ketoacyl synthase, C-terminal domain
426Thiolase, C-terminal domain
11Metal binding domain of Ada
11Alpha amylase, C-terminal all-beta domain
5510Ubiquitin interaction motif
11PHP domain
123Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
5712MIR domain
224e3 binding domain
112ATP synthase, Delta/Epsilon chain, beta-sandwich domain
336TGS domain
6612D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
112DHHA2 domain
11Glycosyl hydrolases family 2, TIM barrel domain
11Glycosyl hydrolases family 2, sugar binding domain
11Glycosyl hydrolase family 20, domain 2
112Prp18 domain
11
112Phosphoribosylglycinamide synthetase, C domain
112Phosphoribosylglycinamide synthetase, N domain
5712CUE domain
224MA3 domain
336Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
5611MIF4G domain
112Clp amino terminal domain, pathogenicity island component
112DDHD domain
336lactate/malate dehydrogenase, alpha/beta C-terminal domain
224Ribonucleotide reductase, barrel domain
116-O-methylguanine DNA methyltransferase, ribonuclease-like domain
448ATP synthase alpha/beta family, beta-barrel domain