PFAM Domains • Thielavia appendiculata CBS 731.68 v1.0
Annotations/GenomesNeucr2Spoth2Thiap1Thiar1Thihy1Thite2Trire2TotalAnnotation Description
PFAMs
8,0346,9517,7207,9867,2967,3376,50751,831
111147 transmembrane receptor (rhodopsin family)
117 transmembrane receptor (Secretin family)
43414648524344317ATPase family associated with various cellular activities (AAA)
37383540333646265ABC transporter
444444428ATP synthase alpha/beta family, nucleotide-binding domain
18141314151414102Elongation factor Tu GTP binding domain
201312141213993Helix-loop-helix DNA-binding domain
333233320Hsp20/alpha crystallin family
898988757Hsp70 protein
13891099866KH domain
11111117SH2 domain
26212123222324160SH3 domain
1191010810765Actin
53297473674163400Ankyrin repeat
13311211PAN domain
978877753ADP-ribosylation factor family
19161616142216119Eukaryotic aspartyl protease
644444430Cyclic nucleotide-binding domain
11111117Cytochrome c
111126Double-stranded RNA binding motif
18171717162020125EF hand
311111194Fe-4S binding domain
323332117Fibronectin type III domain
221221212Globin
6811101091064Glutathione S-transferase, C-terminal domain
11111117Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
755766541Homeodomain
442323220lactate/malate dehydrogenase, NAD binding domain
554444430Myosin head (motor domain)
41526389495969422Cytochrome P450
134117101153113134106858Protein kinase domain
1312151712131496Pyridine nucleotide-disulphide oxidoreductase
28242725272423178Ras family
1711131613111394Response regulator receiver domain
232521217RNase H
74586262636259440RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
11Retroviral aspartyl protease
145Reverse transcriptase (RNA-dependent DNA polymerase)
312223215Copper/zinc superoxide dismutase (SODC)
322222215Iron/manganese superoxide dismutases, alpha-hairpin domain
88141311101579Subtilase family
38425044354276327Sugar (and other) transporter
1111111212121180Thioredoxin
11111117Trypsin
544444631Tubulin/FtsZ family, GTPase domain
626772232von Willebrand factor type A domain
64535564576067420Zinc finger, C2H2 type
42414042424032279Zinc finger, C3HC4 type (RING finger)
1213810127567Zinc knuckle
222222214Protein-tyrosine phosphatase
6656911056294118592short chain dehydrogenase
33325049334253292Zinc-binding dehydrogenase
555555636Thiolase, N-terminal domain
11181530121917122Beta-ketoacyl synthase, N-terminal domain
6555555362Fe-2S iron-sulfur cluster binding domain
11114Papain family cysteine protease
31111119Enolase, C-terminal TIM barrel domain
22Cytochrome C and Quinol oxidase polypeptide I
1198888759Glutamine amidotransferase class-I
1010101010101070TCP-1/cpn60 chaperonin family
544444227Glutamine synthetase, catalytic domain
222222214Triosephosphate isomerase
1314141415121698E1-E2 ATPase
1088889758Core histone H2A/H2B/H3/H4
10811784452Alpha amylase, catalytic domain
221422215Phorbol esters/diacylglycerol binding domain (C1 domain)
988777854Bacterial transferase hexapeptide (six repeats)
335354629tRNA synthetases class I (I, L, M and V)
757667745Cyclin, N-terminal domain
11911117141275Carboxylesterase family
444444428DNA polymerase family B
456665436ATP synthase subunit C
646454635Peroxidase
6561246847Beta-lactamase
233333118C-5 cytosine-specific DNA methylase
32242329262927190Calcineurin-like phosphoesterase
58611613453Cellulase (glycosyl hydrolase family 5)
878778853tRNA synthetases class II (D, K and N)
40373738363535258Mitochondrial carrier protein
1412151515121699Aminotransferase class I and II
1081191110867Phosphoribosyl transferase domain
1110101010101071Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
11111117Phosphoglycerate kinase
222222214Ribosomal protein S4/S9 N-terminal domain
312222214Ribosomal protein S12/S23
112Bacterial regulatory helix-turn-helix proteins, AraC family
1111116Chaperonin 10 Kd subunit
1413111414111491C2 domain
28171817181519132PH domain
98108891163bZIP transcription factor
1613111410152099Aldehyde dehydrogenase family
139101142137120122192953Fungal Zn(2)-Cys(6) binuclear cluster domain
23212223222221154Cytochrome b5-like Heme/Steroid binding domain
423322420Oxidoreductase molybdopterin binding domain
15131917141414106Oxidoreductase NAD-binding domain
28232124272625174SNF2 family N-terminal domain
221222213Ribosomal protein S7p/S5e
20202021212020142Ubiquitin-conjugating enzyme
755555739Isocitrate/isopropylmalate dehydrogenase
222212213Ribosomal Proteins L2, RNA binding domain
11111117Hsp90 protein
222222214Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
11111117Dihydrofolate reductase
226333221Chitin recognition protein
311211312Cysteine-rich secretory protein family
11111117Ribosomal protein S3, C-terminal domain
121221312Cupin
333332219Annexin
11111117Eukaryotic-type carbonic anhydrase
1111217Chalcone and stilbene synthases, N-terminal domain
3333333212-oxoacid dehydrogenases acyltransferase (catalytic domain)
324331723Catalase
11212119Disintegrin
13228UDP-glucoronosyl and UDP-glucosyl transferase
967877852Aminotransferase class-III
222222214Ribosomal protein S19
21111118DNA gyrase B
645443430Thiamine pyrophosphate enzyme, central domain
333333321Lyase
222222214Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
112Ferritin-like domain
21111118Adenylate and Guanylate cyclase catalytic domain
11111117ATP synthase delta (OSCP) subunit
11111117Orotidine 5'-phosphate decarboxylase / HUMPS family
21111118Indole-3-glycerol phosphate synthase
1111116Aromatic amino acid lyase
22111119Pyruvate kinase, barrel domain
131010108101172Kinesin motor domain
33242626262626187DnaJ domain
1613141414141499Proteasome subunit
113121716Major intrinsic protein
11111117ATP synthase
212121211Glycosyl hydrolase family 1
211111183'5'-cyclic nucleotide phosphodiesterase
21111118Profilin
11111117Ribosomal protein L22p/L17e
222222214Ribosomal protein L14p/L23e
14111111118874Ubiquitin family
635454330Cofilin/tropomyosin-type actin-binding protein
32222221514-3-3 protein
746552332Alkaline phosphatase
233332420Zinc carboxypeptidase
19142723192327152Aldo/keto reductase family
20171415161614112Myb-like DNA-binding domain
444444428Forkhead domain
2316Glycosyl hydrolases family 32 N-terminal domain
11111117Ribosomal protein L16p/L10e
222222113Ribosomal protein S14p/S29e
444444327FKBP-type peptidyl-prolyl cis-trans isomerase
11111117Glutathione peroxidase
222222214
668766746Flavodoxin
11111117Calreticulin family
991212910263Common central domain of tyrosinase
888997352Aminotransferase class-V
11111117Ribonucleotide reductase, small chain
41393940433849289DEAD/DEAH box helicase
80727476797375529Helicase conserved C-terminal domain
11111117EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
222222214Ribosomal protein L23
12111118Pyridoxal-dependent decarboxylase, C-terminal sheet domain
222222214Ribosomal protein L5
656665640Pyridoxal-dependent decarboxylase conserved domain
422222216Citrate synthase, C-terminal domain
665555537GHMP kinases N terminal domain
655555536Biotin carboxylase, N-terminal domain
11111117Tryptophan synthase alpha chain
111011121081274Pyridoxal-phosphate dependent enzyme
18131817141415109NUDIX domain
966665442pfkB family carbohydrate kinase
223217421Glycosyl hydrolases family 28
415Luciferase-like monooxygenase
222222214Ribosomal protein L3
222222214Ribosomal protein L11, RNA binding domain
121116101312680Histidine phosphatase superfamily (branch 1)
11111117Thymidylate synthase
12115Lipoxygenase
444444428ATP synthase alpha/beta chain, C terminal domain
855545537Calponin homology (CH) domain
544444429Glutamine amidotransferases class-II
222221213Ribosomal protein S15
11114Thaumatin family
212231213Fructose-1-6-bisphosphatase, N-terminal domain
11111117Ribonucleotide reductase, all-alpha domain
222222214Ribosomal protein S2
222222214SRF-type transcription factor (DNA-binding and dimerisation domain)
1068878653GATA zinc finger
22192022142133151Amino acid permease
334432120Prolyl oligopeptidase family
222222214Ribosomal protein L30p/L7e
767784443Histidine phosphatase superfamily (branch 2)
11111117Respiratory-chain NADH dehydrogenase, 30 Kd subunit
444444428Aconitase family (aconitate hydratase)
4410756137Glycosyl hydrolase family 10
522222116Glycosyl hydrolases family 17
222122213Ribosomal protein S5, N-terminal domain
11111117Nucleoside diphosphate kinase
112221110Ribosomal protein S10p/S20e
444444327Arrestin (or S-antigen), N-terminal domain
11111117Phosphoglucose isomerase
11111117Carbohydrate phosphorylase
11111117SecY translocase
11111117Respiratory-chain NADH dehydrogenase, 49 Kd subunit
212222213Ribosomal protein L6
346464330Polyprenyl synthetase
444344427Hexokinase
789898958Dynamin family
122222112Transcription factor TFIID (or TATA-binding protein, TBP)
445454430Rieske [2Fe-2S] domain
11Phytochrome region
213Proton-conducting membrane transporter
877766647Biotin-requiring enzyme
11111117Phosphofructokinase
222222214Ribosomal protein S17
11111117Hydroxymethylglutaryl-coenzyme A reductase
333333321FGGY family of carbohydrate kinases, N-terminal domain
1113Sodium:dicarboxylate symporter family
78107871259Enoyl-CoA hydratase/isomerase
222222214Ribosomal protein S9/S16
322222215Transcription factor TFIIB repeat
987566647Cytidine and deoxycytidylate deaminase zinc-binding region
112222111Molybdopterin oxidoreductase
12787137155Chromo (CHRromatin Organisation MOdifier) domain
434343425Phosphatidylinositol-specific phospholipase C, Y domain
634343629Phosphatidylinositol-specific phospholipase C, X domain
667677544D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
322222215Malic enzyme, N-terminal domain
112PEP-utilising enzyme, mobile domain
2112121106-phosphogluconate dehydrogenase, C-terminal domain
1061312711867Multicopper oxidase
11Granulin
99910991065WW domain
11111117Ribosomal RNA adenine dimethylase
112Yeast PIR protein repeat
114106115126128108123820WD domain, G-beta repeat
545455533Heavy-metal-associated domain
433454427Adenylate kinase
122221212Phosphoglucomutase/phosphomannomutase, C-terminal domain
322121213Ribosomal protein S8
11111218Ribosomal protein S11
544444429LIM domain
222213113Regulator of chromosome condensation (RCC1) repeat
212222213Ribosomal protein S13/S18
323222216chorismate binding enzyme
43333332260s Acidic ribosomal protein
444444428Prenyltransferase and squalene oxidase repeat
865665541Protein kinase C terminal domain
21111118Single-strand binding protein family
21111118S-adenosylmethionine synthetase, N-terminal domain
8710978756Bromodomain
9771068855Acyl-CoA dehydrogenase, C-terminal domain
17141414151415103Ubiquitin carboxyl-terminal hydrolase
1111116Ribosomal protein L36
12131311Ribonuclease T2 family
333333321HSF-type DNA-binding
222222214SRP54-type protein, GTPase domain
21111118Urease alpha-subunit, N-terminal domain
454445531Serine carboxypeptidase
898888857Phosphatidylinositol 3- and 4-kinase
112121210Transketolase, thiamine diphosphate binding domain
287535333Glycosyl hydrolases family 11
565455434Inositol monophosphatase family
534443326Glutaredoxin
323432219Isocitrate lyase family
322222215Serine hydroxymethyltransferase
11111128Iron-containing alcohol dehydrogenase
322222215Ribosomal protein L10
433222622KOW motif
112Ribosomal protein L34
322323217RF-1 domain
232223519Sodium:solute symporter family
11111117Imidazoleglycerol-phosphate dehydratase
11111117DNA polymerase family A
11111117IMP dehydrogenase / GMP reductase domain
11111117Glucose-6-phosphate dehydrogenase, NAD binding domain
765585642Protein phosphatase 2C
222222315Nucleotidyl transferase
332324421Carbonic anhydrase
11111128Phosphoribulokinase / Uridine kinase family
555565637Fatty acid desaturase
666666642MutS domain V
11111117Delta-aminolevulinic acid dehydratase
513421319Arginase family
666666642MCM P-loop domain
31111119Squalene/phytoene synthase
10810121010868FHA domain
11NADH-ubiquinone/plastoquinone oxidoreductase chain 6
28313333332737222AMP-binding enzyme
433334323G-protein alpha subunit
15101211109774HMG (high mobility group) box
1381013981071His Kinase A (phospho-acceptor) domain
333233320Armadillo/beta-catenin-like repeat
26212628252424174Tetratricopeptide repeat
323234522Ion transport protein
21111118DNA gyrase/topoisomerase IV, subunit A
1010107871163BRCA1 C Terminus (BRCT) domain
9710896655Glycosyl transferases group 1
433433323Glycosyl transferase family 2
311212313SAM domain (Sterile alpha motif)
21111118linker histone H1 and H5 family
11111117Ribosomal protein L7/L12 C-terminal domain
1554621Pectate lyase
223111111ribonuclease
21111118Urease, gamma subunit
443333525CoA-ligase
8161325121719110Phosphopantetheine attachment site
333332320Formyl transferase
1089788858Metallopeptidase family M24
19161515161516112Leucine Rich Repeat
24252931242622181alpha/beta hydrolase fold
333333321RNA polymerase Rpb2, domain 6
444444428PB1 domain
222222214Staphylococcal nuclease homologue
1091099101067Rab-GTPase-TBC domain
11111117Tudor domain
11111117WH1 domain
433333524Zinc finger, ZZ type
122122111HRDC domain
11891089964CBS domain
312222214Ribosomal protein L13
322222215Ribosomal protein L4/L1 family
11111117Clp protease
533453528S1 RNA binding domain
31111119HIUase/Transthyretin family
322332318AhpC/TSA family
444544429tRNA synthetases class I (W and Y)
11114UvrD/REP helicase N-terminal domain
455666436Rhodanese-like domain
522222217Universal stress protein family
31283340293140232Acetyltransferase (GNAT) family
11111117SecE/Sec61-gamma subunits of protein translocation complex
21111118C-terminal regulatory domain of Threonine dehydratase
222222214AIR synthase related protein, N-terminal domain
108881110863tRNA synthetase class II core domain (G, H, P, S and T)
11111117SpoU rRNA Methylase family
222222214Tetrapyrrole (Corrin/Porphyrin) Methylases
11111117Glycosyl transferase family, a/b domain
1111116PDZ domain
221312314Class II Aldolase and Adducin N-terminal domain
11Adenoviral fibre protein (repeat/shaft region)
544444429Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
445445329Fes/CIP4, and EFC/F-BAR homology domain
855554537IQ calmodulin-binding motif
222222214Phosphoinositide 3-kinase family, accessory domain (PIK domain)
667666542Phospholipase D Active site motif
21111118Regulator of G protein signaling domain
744444431GTPase-activator protein for Ras-like GTPase
644444430RasGEF domain
644444228RasGEF N-terminal motif
151089910869RhoGAP domain
766656541RhoGEF domain
333535325SPRY domain
333333321RNA polymerase Rpb1, domain 2
232242318Guanylate kinase
434334425Gelsolin repeat
10116769756UBA/TS-N domain
18161517161515112PHD-finger
11111117GGL domain
1066665645HECT-domain (ubiquitin-transferase)
233332218Helix-hairpin-helix motif
11111117MSP (Major sperm protein) domain
554444430Ribonuclease III domain
333233219Region in Clathrin and VPS
433233321RanBP1 domain
312222214PPIC-type PPIASE domain
423333220Zn-finger in Ran binding protein and others
15121515201715109Zinc finger C-x8-C-x5-C-x3-H type (and similar)
122122111Poly(ADP-ribose) polymerase catalytic domain
1121117Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
44394650474651323F-box domain
11111117Elongation factor 1 gamma, conserved domain
523333322Calpain family cysteine protease
22211210Copper fist DNA binding domain
665556538CRAL/TRIO domain
895675545BTB/POZ domain
322212416Ricin-type beta-trefoil lectin domain
11111117Inhibitor of Apoptosis domain
433333322Voltage gated chloride channel
223222215Caspase domain
101114111010571GDSL-like Lipase/Acylhydrolase
11111117Poly-adenylate binding protein, unique domain
11POLO box duplicated region
20201820161925138ABC transporter transmembrane region
112Integrase core domain
556765640FAD binding domain
31067741047Condensation domain
21111118S-adenosyl-L-homocysteine hydrolase, NAD binding domain
11111117HAMP domain
222222214ribosomal L5P family C-terminus
644646535Insulinase (Peptidase family M16)
333333321Dehydrogenase E1 component
11111117Lumazine binding domain
865675542Elongation factor G C-terminus
644444430HMGL-like
644444430DnaJ central domain
322123114Starch binding domain
222222214Ribosomal protein L1p/L10e family
788896955Cation transporting ATPase, C-terminus
89871071059Cation transporter/ATPase, N-terminus
11121118dUTPase
444444428Aconitase C-terminal domain
433333322Amino acid kinase family
21111118N-(5'phosphoribosyl)anthranilate (PRA) isomerase
10151329101617110Acyl transferase domain
21111118Urease beta subunit
435555633Dihydrodipicolinate synthetase family
29303033303031213haloacid dehalogenase-like hydrolase
675758745Glycosyl hydrolases family 2
98171315131994Glycosyl hydrolases family 18
11111117Proliferating cell nuclear antigen, N-terminal domain
11Translation initiation factor IF-3, C-terminal domain
11114Acylphosphatase
11111117Adenylosuccinate synthetase
411111110Asparaginase, N-terminal
11Beta defensin
332322217Peptidase S24-like
222222214Inorganic pyrophosphatase
1310910991373Glycosyl hydrolases family 16
222223215Glycosyl hydrolases family 15
324423826NADH:flavin oxidoreductase / NADH oxidase family
4222232173-hydroxyacyl-CoA dehydrogenase, C-terminal domain
211111310Glycosyl hydrolase family 20, catalytic domain
655555536HhH-GPD superfamily base excision DNA repair protein
11111117AIR carboxylase
711192011151295GMC oxidoreductase
242223217Asparagine synthase
21173021322514160Fungal cellulose binding domain
655555536Septin
11211118EF-1 guanine nucleotide exchange domain
11111117Homoserine dehydrogenase
11Flavin-binding monooxygenase-like
11LPXTG cell wall anchor motif
334555328tRNA synthetases class I (E and Q), catalytic domain
112232112tRNA synthetases class I (R)
444443326XPG N-terminal domain
13910118121073Metallo-beta-lactamase superfamily
213F5/8 type C domain
233233218Choline/Carnitine o-acyltransferase
112221110Putative esterase
11111117Ferrochelatase
422222216Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
211112210Arginosuccinate synthase
11111117Electron transfer flavoprotein FAD-binding domain
333333321RNB domain
456756437Dioxygenase
432322218CNH domain
322222114Diacylglycerol kinase catalytic domain
777787447Dual specificity phosphatase, catalytic domain
44
532223320P21-Rho-binding domain
1613121212121289PX domain
433433323Ras association (RalGDS/AF-6) domain
634434428UBX domain
444444428VHS domain
11111117Phosphoinositide 3-kinase C2
222222214DAHP synthetase I family
115119771262Carbon-nitrogen hydrolase
1121218N-acetyltransferase
21111118Prephenate dehydratase
744444431Syntaxin
855555538Pumilio-family RNA binding repeat
976667546Histone-like transcription factor (CBF/NF-Y) and archaeal histone
11111117Pterin binding enzyme
222222214ER lumen protein retaining receptor
322222215Glycoprotease family
11111117Histidinol dehydrogenase
544443428impB/mucB/samB family
11111117
11111117Ribosomal L15
1111116Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
1111116Ribosomal L28 family
11111117Ribosomal L29 protein
11111117Ribosomal L39 protein
11111117Ribosomal S17
11111117Ribulose-phosphate 3 epimerase family
11111117Translationally controlled tumour protein
566735234Glycosyl hydrolase family 7
21111118RNA pseudouridylate synthase
444444428Histone deacetylase domain
122321314POT family
11111117PWWP domain
1917162115189115SET domain
345564734Isochorismatase family
433333221Permease family
11111117Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
544444429XPG I-region
11111117Acetokinase family
235DNA photolyase
213NlpC/P60 family
11Cation-independent mannose-6-phosphate receptor repeat
112Nitroreductase family
322414521Sulfatase