PFAM Domains • Earliella scabrosa CIRM-BRFM 1817 v1.0
Annotations/GenomesDicsq1Earsca1Fomfom1Hexnit1Polar1Polbr1Pyccin1Trave1TotalAnnotation Description
PFAMs
8,07211,36410,55310,4909,1439,1629,1398,61476,537
4445454248493947359ATPase family associated with various cellular activities (AAA)
3851534948473745368ABC transporter
4444444432ATP synthase alpha/beta family, nucleotide-binding domain
11EGF-like domain
1416171515141614121Elongation factor Tu GTP binding domain
101010141111101187Helix-loop-helix DNA-binding domain
14111113111011990Hsp20/alpha crystallin family
14109101197777Hsp70 protein
14777886865KH domain
1113SH2 domain
2416141624241325156SH3 domain
11u-PAR/Ly-6 domain
101011101010101081Actin
175432424426107Ankyrin repeat
7777777756ADP-ribosylation factor family
4445405049564253379Eukaryotic aspartyl protease
3333333324Cyclic nucleotide-binding domain
111111118Cytochrome c
7786989559Double-stranded RNA binding motif
19119191876EF hand
111254Fe-4S binding domain
12115Fibronectin type III domain
1121111210Globin
181619102221725138Glutathione S-transferase, C-terminal domain
111111118Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
112Hemopexin
7171514161599102Homeodomain
112Laminin EGF domain
2222222216lactate/malate dehydrogenase, NAD binding domain
6546565441Myosin head (motor domain)
1722401992242021941041851,520Cytochrome P450
1472402072031881951721861,538Protein kinase domain
1612111117171016110Pyridine nucleotide-disulphide oxidoreductase
2227272724242629206Ras family
8999999971Response regulator receiver domain
8189254820642176RNase H
6063605671705666502RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
134Reverse transcriptase (RNA-dependent DNA polymerase)
111111118Copper/zinc superoxide dismutase (SODC)
3211562323Iron/manganese superoxide dismutases, alpha-hairpin domain
635332744235137Subtilase family
3145464634323931304Sugar (and other) transporter
811101210149882Thioredoxin
5655775545Tubulin/FtsZ family, GTPase domain
4232314von Willebrand factor type A domain
5033292162662060341Zinc finger, C2H2 type
591411116770757296Zinc finger, C3HC4 type (RING finger)
311610121617828138Zinc knuckle
2333222219Protein-tyrosine phosphatase
821209511212812765113842short chain dehydrogenase
6454626068734173495Zinc-binding dehydrogenase
4555445436Thiolase, N-terminal domain
4467454337Beta-ketoacyl synthase, N-terminal domain
21113313152Fe-2S iron-sulfur cluster binding domain
111111118Enolase, C-terminal TIM barrel domain
78888881065Glutamine amidotransferase class-I
101010121110101083TCP-1/cpn60 chaperonin family
3333333324Glutamine synthetase, catalytic domain
111111118Triosephosphate isomerase
1420161715151611124E1-E2 ATPase
1916161618201614135Core histone H2A/H2B/H3/H4
111115Copper binding proteins, plastocyanin/azurin family
81088886662Alpha amylase, catalytic domain
6676666649Phorbol esters/diacylglycerol binding domain (C1 domain)
5344345533Bacterial transferase hexapeptide (six repeats)
3444345330tRNA synthetases class I (I, L, M and V)
121512121012111094Cyclin, N-terminal domain
2433342740421520235Carboxylesterase family
4544444433DNA polymerase family B
3333333324ATP synthase subunit C
1427172321201027159Peroxidase
58571074753Beta-lactamase
4445554435C-5 cytosine-specific DNA methylase
2524252428281927200Calcineurin-like phosphoesterase
1221242111121413128Cellulase (glycosyl hydrolase family 5)
7666776651tRNA synthetases class II (D, K and N)
3738374137413936306Mitochondrial carrier protein
11recA bacterial DNA recombination protein
1822252321201920168Aminotransferase class I and II
6333773739Phosphoribosyl transferase domain
1216151414151314113Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
111111118Phosphoglycerate kinase
2222222216Ribosomal protein S4/S9 N-terminal domain
2222222216Ribosomal protein S12/S23
111111118Chaperonin 10 Kd subunit
1213131319131114108C2 domain
221010923251020129PH domain
5988668656bZIP transcription factor
1924271623181717161Aldehyde dehydrogenase family
7766587292946484607Fungal Zn(2)-Cys(6) binuclear cluster domain
2323252324252224189Cytochrome b5-like Heme/Steroid binding domain
3444445432Oxidoreductase molybdopterin binding domain
1212191112121115104Oxidoreductase NAD-binding domain
2123212420202320172SNF2 family N-terminal domain
2222222317Ribosomal protein S7p/S5e
2023222221212020169Ubiquitin-conjugating enzyme
5655555541Isocitrate/isopropylmalate dehydrogenase
2222222216Ribosomal Proteins L2, RNA binding domain
2222222216Hsp90 protein
2222223318Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
11111117Dihydrofolate reductase
112Chitin recognition protein
2222552222Cysteine-rich secretory protein family
11111117Ribosomal protein S3, C-terminal domain
7767776653Cupin
1113Eukaryotic-type carbonic anhydrase
33333333242-oxoacid dehydrogenases acyltransferase (catalytic domain)
3443584334Catalase
111111118Disintegrin
6178588161987UDP-glucoronosyl and UDP-glucosyl transferase
5555558543Aminotransferase class-III
2222223217Ribosomal protein S19
2211111110DNA gyrase B
4474554437Thiamine pyrophosphate enzyme, central domain
3333333324Lyase
121111119Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
111111118Adenylate and Guanylate cyclase catalytic domain
11112118ATP synthase delta (OSCP) subunit
11111117Orotidine 5'-phosphate decarboxylase / HUMPS family
2321221114Indole-3-glycerol phosphate synthase
3111111110Aromatic amino acid lyase
111111118Pyruvate kinase, barrel domain
9999899971Kinesin motor domain
2832343132333031251DnaJ domain
1414191414141414117Proteasome subunit
5455554538Major intrinsic protein
111111118ATP synthase
4222222218Glycosyl hydrolase family 1
1111111183'5'-cyclic nucleotide phosphodiesterase
111111118Profilin
1222112112Ribosomal protein L22p/L17e
232222215Ribosomal protein L14p/L23e
1720181719171717142Ubiquitin family
5555555439Cofilin/tropomyosin-type actin-binding protein
122223221614-3-3 protein
22122312Alkaline phosphatase
111111118Zinc carboxypeptidase
6168524960584867463Aldo/keto reductase family
13666141471278Myb-like DNA-binding domain
5545555640Forkhead domain
2213111314Glycosyl hydrolases family 32 N-terminal domain
1222112112Ribosomal protein L16p/L10e
1222222215Ribosomal protein S14p/S29e
3363333327FKBP-type peptidyl-prolyl cis-trans isomerase
111111129Glutathione peroxidase
11125
691381086666Flavodoxin
1113Tropomyosin
111111118Calreticulin family
3455332530Common central domain of tyrosinase
79879971066Aminotransferase class-V
230251182363Ribonucleotide reductase, small chain
5258546751528246462DEAD/DEAH box helicase
89847689848710176686Helicase conserved C-terminal domain
1161111113EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
2222222216Ribosomal protein L23
111111118Pyridoxal-dependent decarboxylase, C-terminal sheet domain
111111118Ribosomal protein L5
4334334428Pyridoxal-dependent decarboxylase conserved domain
3444334328Citrate synthase, C-terminal domain
5555555540GHMP kinases N terminal domain
6797788759Biotin carboxylase, N-terminal domain
1111111310Tryptophan synthase alpha chain
988891091172Pyridoxal-phosphate dependent enzyme
11'Paired box' domain
1515151615151615122NUDIX domain
3443333326pfkB family carbohydrate kinase
79161111117981Glycosyl hydrolases family 28
2222222216Ribosomal protein L3
2222222216Ribosomal protein L11, RNA binding domain
7878998763Histidine phosphatase superfamily (branch 1)
1122321113Thymidylate synthase
112Lipoxygenase
4444444432ATP synthase alpha/beta chain, C terminal domain
4444444432Calponin homology (CH) domain
5333553532Glutamine amidotransferases class-II
2222222216Ribosomal protein S15
4779555850Thaumatin family
111111118Fructose-1-6-bisphosphatase, N-terminal domain
138111051259Ribonucleotide reductase, all-alpha domain
322222215Ribosomal protein S2
2232222217SRF-type transcription factor (DNA-binding and dimerisation domain)
10101110111010981GATA zinc finger
2411992625824136Amino acid permease
4557554439Prolyl oligopeptidase family
2222222115Ribosomal protein L30p/L7e
1412131213131215104Histidine phosphatase superfamily (branch 2)
111111118Respiratory-chain NADH dehydrogenase, 30 Kd subunit
4544554536Aconitase family (aconitate hydratase)
5775665647Glycosyl hydrolase family 10
1111116Glycosyl hydrolases family 17
2222222216Ribosomal protein S5, N-terminal domain
2222222216Nucleoside diphosphate kinase
246413121Tetraspanin family
2222222216Ribosomal protein S10p/S20e
71176774756Arrestin (or S-antigen), N-terminal domain
11111117Phosphoglucose isomerase
11111117Carbohydrate phosphorylase
111111118SecY translocase
111111118Respiratory-chain NADH dehydrogenase, 49 Kd subunit
2222222216Ribosomal protein L6
8554443336Polyprenyl synthetase
2322221216Hexokinase
61711128810880Dynamin family
1311121111Transcription factor TFIID (or TATA-binding protein, TBP)
3332443426Rieske [2Fe-2S] domain
111115Phytochrome region
89899910971Biotin-requiring enzyme
111111118Phosphofructokinase
3222222217Ribosomal protein S17
111111118Hydroxymethylglutaryl-coenzyme A reductase
3333443427FGGY family of carbohydrate kinases, N-terminal domain
891081087868Enoyl-CoA hydratase/isomerase
2222222216Ribosomal protein S9/S16
4222332220Transcription factor TFIIB repeat
6888998763Cytidine and deoxycytidylate deaminase zinc-binding region
111111118Molybdopterin oxidoreductase
1186717116975Chromo (CHRromatin Organisation MOdifier) domain
1222111111Phosphatidylinositol-specific phospholipase C, Y domain
1333211115Phosphatidylinositol-specific phospholipase C, X domain
7766776753D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
3333333324Malic enzyme, N-terminal domain
22123222166-phosphogluconate dehydrogenase, C-terminal domain
13101012111171084Multicopper oxidase
78871098764WW domain
2223342220Ribosomal RNA adenine dimethylase
1921801431591641631341291,264WD domain, G-beta repeat
4645444536Heavy-metal-associated domain
3433333325Adenylate kinase
1323223117Phosphoglucomutase/phosphomannomutase, C-terminal domain
1322112113Ribosomal protein S8
1222112112Ribosomal protein S11
6566666546LIM domain
2556445233Regulator of chromosome condensation (RCC1) repeat
1222222114Ribosomal protein S13/S18
3222222217chorismate binding enzyme
332322232060s Acidic ribosomal protein
4454544434Prenyltransferase and squalene oxidase repeat
6556665645Protein kinase C terminal domain
111111118Single-strand binding protein family
111111118S-adenosylmethionine synthetase, N-terminal domain
81210101110101081Bromodomain
1012109101091080Acyl-CoA dehydrogenase, C-terminal domain
1415181614141314118Ubiquitin carboxyl-terminal hydrolase
11111117Ribosomal protein L36
2222222216Ribonuclease T2 family
5555555641HSF-type DNA-binding
2222222216SRP54-type protein, GTPase domain
2212111111Urease alpha-subunit, N-terminal domain
1826212721211924177Serine carboxypeptidase
8888998967Phosphatidylinositol 3- and 4-kinase
2222222216Transketolase, thiamine diphosphate binding domain
111115WHEP-TRS domain
3332222219Inositol monophosphatase family
4544444433Glutaredoxin
4222442424Isocitrate lyase family
111121119Serine hydroxymethyltransferase
3455334330Iron-containing alcohol dehydrogenase
2222222216Ribosomal protein L10
4344444532KOW motif
111111118Ribosomal protein L34
1113Ribosomal protein L33
3333224323RF-1 domain
2323222218Sodium:solute symporter family
111111118Imidazoleglycerol-phosphate dehydratase
111111118DNA polymerase family A
2211111110IMP dehydrogenase / GMP reductase domain
111111118Glucose-6-phosphate dehydrogenase, NAD binding domain
7991011107871Protein phosphatase 2C
3333333223Nucleotidyl transferase
6333542531Carbonic anhydrase
111111118Phosphoribulokinase / Uridine kinase family
91011101011111688Fatty acid desaturase
5666666647MutS domain V
111111118Delta-aminolevulinic acid dehydratase
5557555441Arginase family
6866666650MCM P-loop domain
1222112112Squalene/phytoene synthase
1214141213151213105FHA domain
3441383837363433291AMP-binding enzyme
1518171518171414128G-protein alpha subunit
1618181620191528150HMG (high mobility group) box
5565665543His Kinase A (phospho-acceptor) domain
3334333325Armadillo/beta-catenin-like repeat
2617151828281226170Tetratricopeptide repeat
2434333325Ion transport protein
111111118DNA gyrase/topoisomerase IV, subunit A
11Binding-protein-dependent transport system inner membrane component
8555121271165BRCA1 C Terminus (BRCT) domain
7454664642Glycosyl transferases group 1
3333663431Glycosyl transferase family 2
1111116SAM domain (Sterile alpha motif)
2333332322linker histone H1 and H5 family
111111118Ribosomal protein L7/L12 C-terminal domain
322211112ribonuclease
2212111111Urease, gamma subunit
3333333324CoA-ligase
910131610911886Phosphopantetheine attachment site
2222222216Formyl transferase
101213121112121092Metallopeptidase family M24
16253161441474Leucine Rich Repeat
4320191451491363272alpha/beta hydrolase fold
3333333324RNA polymerase Rpb2, domain 6
5565653540PB1 domain
2323422220Staphylococcal nuclease homologue
91211121010121086Rab-GTPase-TBC domain
111111118Tudor domain
2222222216WH1 domain
4664683643Zinc finger, ZZ type
111111118HRDC domain
10966997965CBS domain
2222222216Ribosomal protein L13
2222222216Ribosomal protein L4/L1 family
111111118Clp protease
3444334328S1 RNA binding domain
111111118HIUase/Transthyretin family
4455454536AhpC/TSA family
4444444331tRNA synthetases class I (W and Y)
1323222116UvrD/REP helicase N-terminal domain
4898448550Rhodanese-like domain
2222222216Universal stress protein family
3027251743441838242Acetyltransferase (GNAT) family
11111117SecE/Sec61-gamma subunits of protein translocation complex
111111118C-terminal regulatory domain of Threonine dehydratase
2222222216AIR synthase related protein, N-terminal domain
6555665644tRNA synthetase class II core domain (G, H, P, S and T)
11Phage integrase family
2222222317Tetrapyrrole (Corrin/Porphyrin) Methylases
1111114111Glycosyl transferase family, a/b domain
2332111316Class II Aldolase and Adducin N-terminal domain
3545334330Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
4555555640Fes/CIP4, and EFC/F-BAR homology domain
4222332422IQ calmodulin-binding motif
2222222216Phosphoinositide 3-kinase family, accessory domain (PIK domain)
3111331316Phospholipase D Active site motif
1333113116Regulator of G protein signaling domain
4444444432GTPase-activator protein for Ras-like GTPase
7666556546RasGEF domain
7655666647RasGEF N-terminal motif
1213131313131313103RhoGAP domain
1314141513131512109RhoGEF domain
2444444430SPRY domain
3333333324RNA polymerase Rpb1, domain 2
111111118Guanylate kinase
4434453431Gelsolin repeat
7665876954UBA/TS-N domain
1716161720211719143PHD-finger
1222112213GGL domain
4434444431HECT-domain (ubiquitin-transferase)
21111118Helix-hairpin-helix motif
111111118MSP (Major sperm protein) domain
7333774539Ribonuclease III domain
2436224225Region in Clathrin and VPS
2443444328RanBP1 domain
3221342219PPIC-type PPIASE domain
5134452428Zn-finger in Ran binding protein and others
2218151225271422155Zinc finger C-x8-C-x5-C-x3-H type (and similar)
111111118B-box zinc finger
2574332329Poly(ADP-ribose) polymerase catalytic domain
2222332218Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
10045232424025421176883F-box domain
111111118Elongation factor 1 gamma, conserved domain
11111117Calpain family cysteine protease
1222222114Copper fist DNA binding domain
6666666749CRAL/TRIO domain
3088627246563347434BTB/POZ domain
8333971337Ricin-type beta-trefoil lectin domain
111111118Inhibitor of Apoptosis domain
3334333325Voltage gated chloride channel
101010710116771Caspase domain
101310159127985GDSL-like Lipase/Acylhydrolase
111111118Poly-adenylate binding protein, unique domain
111111118POLO box duplicated region
1822272524241825183ABC transporter transmembrane region
213Integrase core domain
58137555553FAD binding domain
2212111313Condensation domain
111111118S-adenosyl-L-homocysteine hydrolase, NAD binding domain
111111118HAMP domain
2222222216ribosomal L5P family C-terminus
6666666648Insulinase (Peptidase family M16)
4444445534Dehydrogenase E1 component
111111118Lumazine binding domain
6666667649Elongation factor G C-terminus
4658786448HMGL-like
4444444331DnaJ central domain
2333222421Starch binding domain
2342223220Ribosomal protein L1p/L10e family
7878776555Cation transporting ATPase, C-terminus
71077897661Cation transporter/ATPase, N-terminus
111111118dUTPase
4544554536Aconitase C-terminal domain
3433333325Amino acid kinase family
111111118N-(5'phosphoribosyl)anthranilate (PRA) isomerase
4467686445Acyl transferase domain
2212111111Urease beta subunit
2333333323Dihydrodipicolinate synthetase family
3418161437351326193haloacid dehalogenase-like hydrolase
2343222220Glycosyl hydrolases family 2
1417151514141111111Glycosyl hydrolases family 18
1211111210Proliferating cell nuclear antigen, N-terminal domain
11114Translation initiation factor IF-3, C-terminal domain
111111118Acylphosphatase
111111118Adenylosuccinate synthetase
111111118Asparaginase, N-terminal
2442223221Peptidase S24-like
111111118Inorganic pyrophosphatase
617191381014693Glycosyl hydrolases family 16
2222222418Glycosyl hydrolases family 15
132117162323915137NADH:flavin oxidoreductase / NADH oxidase family
1111111183-hydroxyacyl-CoA dehydrogenase, C-terminal domain
4556555641Glycosyl hydrolase family 20, catalytic domain
5665556947HhH-GPD superfamily base excision DNA repair protein
111111118AIR carboxylase
3738383233342122255GMC oxidoreductase
2222222216Asparagine synthase
1724242221202222172Fungal cellulose binding domain
7666666649Septin
112111119EF-1 guanine nucleotide exchange domain
111111118Homoserine dehydrogenase
4345543331Flavin-binding monooxygenase-like
112LPXTG cell wall anchor motif
2333333323tRNA synthetases class I (E and Q), catalytic domain
1121221111tRNA synthetases class I (R)
5957777552XPG N-terminal domain
1212141318191015113Metallo-beta-lactamase superfamily
11111117F5/8 type C domain
4474444435Choline/Carnitine o-acyltransferase
111111118Putative esterase
11111117Glycosyl hydrolase family 9
111111118Ferrochelatase
2222222216Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112111119Arginosuccinate synthase
111111118Electron transfer flavoprotein FAD-binding domain
3433332324RNB domain
2454553331Dioxygenase
4668457545CNH domain
2322222217Diacylglycerol kinase catalytic domain
1114121713131313106Dual specificity phosphatase, catalytic domain
111111118MyTH4 domain