PFAM Domains • Neurospora hispaniola FGSC 10403 v1.0
Annotations/GenomesNeucr2Neucr_trp3_1Neudi1Neuhi1Neute_matA2Neute_mat_a1TotalAnnotation Description
PFAMs
8,0347,1135,6158,6626,8276,85943,110
227 transmembrane receptor (Secretin family)
434134414140240ATPase family associated with various cellular activities (AAA)
373634353434210ABC transporter
44444424ATP synthase alpha/beta family, nucleotide-binding domain
18141315141488Elongation factor Tu GTP binding domain
20141413141388Helix-loop-helix DNA-binding domain
33233317Hsp20/alpha crystallin family
877107746Hsp70 protein
139989957KH domain
111115SH2 domain
262123132222127SH3 domain
1197109955Actin
534740144246242Ankyrin repeat
111115PAN domain
97777744ADP-ribosylation factor family
191717181717105Eukaryotic aspartyl protease
64434425Cyclic nucleotide-binding domain
1111116Cytochrome c
112Double-stranded RNA binding motif
1817213161590EF hand
3111174Fe-4S binding domain
33313316Fibronectin type III domain
22222212Globin
66447633Glutathione S-transferase, C-terminal domain
1111116Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
76556635Homeodomain
43333319lactate/malate dehydrogenase, NAD binding domain
55444426Myosin head (motor domain)
414141404141245Cytochrome P450
13410293111101100641Protein kinase domain
13121112101068Pyridine nucleotide-disulphide oxidoreductase
282524272425153Ras family
17141414141487Response regulator receiver domain
22163317RNase H
746262536160372RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
112Retroviral aspartyl protease
11Reverse transcriptase (RNA-dependent DNA polymerase)
32242215Copper/zinc superoxide dismutase (SODC)
32222213Iron/manganese superoxide dismutases, alpha-hairpin domain
86798846Subtilase family
383958444040259Sugar (and other) transporter
1110911101061Thioredoxin
1111116Trypsin
54444425Tubulin/FtsZ family, GTPase domain
66315526von Willebrand factor type A domain
645774185554322Zinc finger, C2H2 type
42403564040203Zinc finger, C3HC4 type (RING finger)
129566543Zinc knuckle
23222314Protein-tyrosine phosphatase
665753545454338short chain dehydrogenase
332832282727175Zinc-binding dehydrogenase
55655531Thiolase, N-terminal domain
119999956Beta-ketoacyl synthase, N-terminal domain
655355292Fe-2S iron-sulfur cluster binding domain
32222213Enolase, C-terminal TIM barrel domain
11Cytochrome C oxidase subunit II, periplasmic domain
119999956Glutamine amidotransferase class-I
10101010101060TCP-1/cpn60 chaperonin family
11ATP synthase A chain
54444425Glutamine synthetase, catalytic domain
22222212Triosephosphate isomerase
13131318131383E1-E2 ATPase
108777746Core histone H2A/H2B/H3/H4
109999955Alpha amylase, catalytic domain
2211219Phorbol esters/diacylglycerol binding domain (C1 domain)
99889952Bacterial transferase hexapeptide (six repeats)
33753324tRNA synthetases class I (I, L, M and V)
76885539Cyclin, N-terminal domain
119999956Carboxylesterase family
44444424DNA polymerase family B
45443323ATP synthase subunit C
63333321Peroxidase
66256631Beta-lactamase
22222212C-5 cytosine-specific DNA methylase
322725232626159Calcineurin-like phosphoesterase
55465530Cellulase (glycosyl hydrolase family 5)
87777743tRNA synthetases class II (D, K and N)
403735373636221Mitochondrial carrier protein
1412913111271Aminotransferase class I and II
109848847Phosphoribosyl transferase domain
11101010101061Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
1111116Phosphoglycerate kinase
22122211Ribosomal protein S4/S9 N-terminal domain
3222211Ribosomal protein S12/S23
1111116Chaperonin 10 Kd subunit
1412129121271C2 domain
28181881718107PH domain
977147751bZIP transcription factor
16131314131382Aldehyde dehydrogenase family
13912498106100103670Fungal Zn(2)-Cys(6) binuclear cluster domain
232121212121128Cytochrome b5-like Heme/Steroid binding domain
43333319Oxidoreductase molybdopterin binding domain
15151414151588Oxidoreductase NAD-binding domain
282523242424148SNF2 family N-terminal domain
22222212Ribosomal protein S7p/S5e
201917191919113Ubiquitin-conjugating enzyme
75555532Isocitrate/isopropylmalate dehydrogenase
22222212Ribosomal Proteins L2, RNA binding domain
1111116Hsp90 protein
22222212Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
1111116Dihydrofolate reductase
221229Chitin recognition protein
33333318Cysteine-rich secretory protein family
1111116Ribosomal protein S3, C-terminal domain
1111116Cupin
32222213Annexin
111115Eukaryotic-type carbonic anhydrase
1111116Chalcone and stilbene synthases, N-terminal domain
333333182-oxoacid dehydrogenases acyltransferase (catalytic domain)
33333318Catalase
1111116Disintegrin
115119UDP-glucoronosyl and UDP-glucosyl transferase
96665537Aminotransferase class-III
22222212Ribosomal protein S19
2111117DNA gyrase B
64444426Thiamine pyrophosphate enzyme, central domain
33333318Lyase
22222212Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
2111117Adenylate and Guanylate cyclase catalytic domain
1111116ATP synthase delta (OSCP) subunit
1111116Orotidine 5'-phosphate decarboxylase / HUMPS family
2111117Indole-3-glycerol phosphate synthase
1111116Aromatic amino acid lyase
2111117Pyruvate kinase, barrel domain
13101010101063Kinesin motor domain
332825282627167DnaJ domain
16141214121280Proteasome subunit
1111116Major intrinsic protein
1111116ATP synthase
2111117Glycosyl hydrolase family 1
21111173'5'-cyclic nucleotide phosphodiesterase
2111229Profilin
1124Ribosomal protein L22p/L17e
22122211Ribosomal protein L14p/L23e
14111010101065Ubiquitin family
65354427Cofilin/tropomyosin-type actin-binding protein
3223221414-3-3 protein
75525529Alkaline phosphatase
22222212Zinc carboxypeptidase
191817181818108Aldo/keto reductase family
2017179171797Myb-like DNA-binding domain
44443322Forkhead domain
22231111Glycosyl hydrolases family 32 N-terminal domain
1112117Ribosomal protein L16p/L10e
222129Ribosomal protein S14p/S29e
44444424FKBP-type peptidyl-prolyl cis-trans isomerase
1111116Glutathione peroxidase
2222210
66666636Flavodoxin
1111116Calreticulin family
98587744Common central domain of tyrosinase
88398844Aminotransferase class-V
1111116Ribonucleotide reductase, small chain
414047444041253DEAD/DEAH box helicase
807571726970437Helicase conserved C-terminal domain
1111116EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
22222212Ribosomal protein L23
1111116Pyridoxal-dependent decarboxylase, C-terminal sheet domain
22212211Ribosomal protein L5
66666636Pyridoxal-dependent decarboxylase conserved domain
42232215Citrate synthase, C-terminal domain
66555633GHMP kinases N terminal domain
65555531Biotin carboxylase, N-terminal domain
1111116Tryptophan synthase alpha chain
1110910101060Pyridoxal-phosphate dependent enzyme
181715171717101NUDIX domain
96354532pfkB family carbohydrate kinase
22222212Glycosyl hydrolases family 28
42242216Luciferase-like monooxygenase
22221211Ribosomal protein L3
22222212Ribosomal protein L11, RNA binding domain
1210710101059Histidine phosphatase superfamily (branch 1)
1111116Thymidylate synthase
1111116Lipoxygenase
44444424ATP synthase alpha/beta chain, C terminal domain
85555533Calponin homology (CH) domain
54434424Glutamine amidotransferases class-II
2212119Ribosomal protein S15
1111116Thaumatin family
22222212Fructose-1-6-bisphosphatase, N-terminal domain
1111116Ribonucleotide reductase, all-alpha domain
22221211Ribosomal protein S2
22222212SRF-type transcription factor (DNA-binding and dimerisation domain)
106666640GATA zinc finger
222020112020113Amino acid permease
32152215Prolyl oligopeptidase family
22222212Ribosomal protein L30p/L7e
76566636Histidine phosphatase superfamily (branch 2)
1111116Respiratory-chain NADH dehydrogenase, 30 Kd subunit
44454425Aconitase family (aconitate hydratase)
44454425Glycosyl hydrolase family 10
54133319Glycosyl hydrolases family 17
22222212Ribosomal protein S5, N-terminal domain
1111116Nucleoside diphosphate kinase
1122118Ribosomal protein S10p/S20e
44334422Arrestin (or S-antigen), N-terminal domain
1111116Phosphoglucose isomerase
1111116Carbohydrate phosphorylase
1111116SecY translocase
1111116Respiratory-chain NADH dehydrogenase, 49 Kd subunit
2212119Ribosomal protein L6
33333318Polyprenyl synthetase
43444423Hexokinase
777136646Dynamin family
1111116Transcription factor TFIID (or TATA-binding protein, TBP)
44444424Rieske [2Fe-2S] domain
112116Phytochrome region
87777743Biotin-requiring enzyme
1111116Phosphofructokinase
22122211Ribosomal protein S17
1111116Hydroxymethylglutaryl-coenzyme A reductase
33333318FGGY family of carbohydrate kinases, N-terminal domain
77777742Enoyl-CoA hydratase/isomerase
22222212Ribosomal protein S9/S16
32222213Transcription factor TFIIB repeat
96776641Cytidine and deoxycytidylate deaminase zinc-binding region
1111116Molybdopterin oxidoreductase
129476745Chromo (CHRromatin Organisation MOdifier) domain
44444424Phosphatidylinositol-specific phospholipase C, Y domain
65554429Phosphatidylinositol-specific phospholipase C, X domain
66555532D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
32222213Malic enzyme, N-terminal domain
222222126-phosphogluconate dehydrogenase, C-terminal domain
10101010101060Multicopper oxidase
112Granulin
98878848WW domain
1112117Ribosomal RNA adenine dimethylase
111115Yeast PIR protein repeat
11410410095104106623WD domain, G-beta repeat
55444426Heavy-metal-associated domain
44444424Adenylate kinase
1122118Phosphoglucomutase/phosphomannomutase, C-terminal domain
32222213Ribosomal protein S8
1112117Ribosomal protein S11
54444425LIM domain
2232211Regulator of chromosome condensation (RCC1) repeat
22127Ribosomal protein S13/S18
33333318chorismate binding enzyme
4333331960s Acidic ribosomal protein
44444424Prenyltransferase and squalene oxidase repeat
86336531Protein kinase C terminal domain
2111117Single-strand binding protein family
2111117S-adenosylmethionine synthetase, N-terminal domain
87787744Bromodomain
98888849Acyl-CoA dehydrogenase, C-terminal domain
17141513141487Ubiquitin carboxyl-terminal hydrolase
111115Ribosomal protein L36
1111116Ribonuclease T2 family
33333318HSF-type DNA-binding
22232213SRP54-type protein, GTPase domain
2111117Urease alpha-subunit, N-terminal domain
44444424Serine carboxypeptidase
88888848Phosphatidylinositol 3- and 4-kinase
1111116Transketolase, thiamine diphosphate binding domain
22222212Glycosyl hydrolases family 11
55555530Inositol monophosphatase family
54344424Glutaredoxin
33223316Isocitrate lyase family
32222213Serine hydroxymethyltransferase
1111116Iron-containing alcohol dehydrogenase
32222213Ribosomal protein L10
44444424KOW motif
111115Ribosomal protein L34
11Ribosomal protein L33
33132214RF-1 domain
21222211Sodium:solute symporter family
1111116Imidazoleglycerol-phosphate dehydratase
1111116DNA polymerase family A
1111116IMP dehydrogenase / GMP reductase domain
1111116Glucose-6-phosphate dehydrogenase, NAD binding domain
75555532Protein phosphatase 2C
22222212Nucleotidyl transferase
33233317Carbonic anhydrase
1111116Phosphoribulokinase / Uridine kinase family
56565532Fatty acid desaturase
66666636MutS domain V
1111116Delta-aminolevulinic acid dehydratase
54444425Arginase family
67666637MCM P-loop domain
32232214Squalene/phytoene synthase
1088118853FHA domain
11NADH-ubiquinone/plastoquinone oxidoreductase chain 6
282825282728164AMP-binding enzyme
43333319G-protein alpha subunit
15111010101066HMG (high mobility group) box
13111111111168His Kinase A (phospho-acceptor) domain
33333318Armadillo/beta-catenin-like repeat
262422142021127Tetratricopeptide repeat
33223316Ion transport protein
2111117DNA gyrase/topoisomerase IV, subunit A
109837845BRCA1 C Terminus (BRCT) domain
99789951Glycosyl transferases group 1
44424422Glycosyl transferase family 2
31511112SAM domain (Sterile alpha motif)
2111117linker histone H1 and H5 family
1111116Ribosomal protein L7/L12 C-terminal domain
1111116Pectate lyase
2111117ribonuclease
2111117Urease, gamma subunit
44444424CoA-ligase
887128851Phosphopantetheine attachment site
33333318Formyl transferase
107687745Metallopeptidase family M24
1915142141377Leucine Rich Repeat
24231452221109alpha/beta hydrolase fold
33333318RNA polymerase Rpb2, domain 6
44444424PB1 domain
22222212Staphylococcal nuclease homologue
1010912101061Rab-GTPase-TBC domain
1111116Tudor domain
1111116WH1 domain
43333319Zinc finger, ZZ type
1112229HRDC domain
119879953CBS domain
32222213Ribosomal protein L13
32222213Ribosomal protein L4/L1 family
1111116Clp protease
55355528S1 RNA binding domain
3111118HIUase/Transthyretin family
32322214AhpC/TSA family
44444424tRNA synthetases class I (W and Y)
1113UvrD/REP helicase N-terminal domain
444104430Rhodanese-like domain
52122214Universal stress protein family
312720172524144Acetyltransferase (GNAT) family
1111116SecE/Sec61-gamma subunits of protein translocation complex
2111117C-terminal regulatory domain of Threonine dehydratase
22222212AIR synthase related protein, N-terminal domain
108878849tRNA synthetase class II core domain (G, H, P, S and T)
1111116SpoU rRNA Methylase family
22222212Tetrapyrrole (Corrin/Porphyrin) Methylases
11114Glycosyl transferase family, a/b domain
213PDZ domain
22222212Class II Aldolase and Adducin N-terminal domain
54444425Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
44454425Fes/CIP4, and EFC/F-BAR homology domain
85524428IQ calmodulin-binding motif
22222212Phosphoinositide 3-kinase family, accessory domain (PIK domain)
66536632Phospholipase D Active site motif
21141110Regulator of G protein signaling domain
74443325GTPase-activator protein for Ras-like GTPase
64444426RasGEF domain
64344425RasGEF N-terminal motif
15101010101065RhoGAP domain
76666637RhoGEF domain
33333318SPRY domain
33333318RNA polymerase Rpb1, domain 2
22222212Guanylate kinase
44434423Gelsolin repeat
109637742UBA/TS-N domain
18171413151592PHD-finger
1111116GGL domain
106666640HECT-domain (ubiquitin-transferase)
2221119Helix-hairpin-helix motif
1111116MSP (Major sperm protein) domain
54344424Ribonuclease III domain
33143317Region in Clathrin and VPS
44333320RanBP1 domain
32212212PPIC-type PPIASE domain
43323318Zn-finger in Ran binding protein and others
1512147121272Zinc finger C-x8-C-x5-C-x3-H type (and similar)
1111116Poly(ADP-ribose) polymerase catalytic domain
111115Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
443937103736203F-box domain
1111116Elongation factor 1 gamma, conserved domain
54444425Calpain family cysteine protease
22222212Copper fist DNA binding domain
65555531CRAL/TRIO domain
883128847BTB/POZ domain
32112211Ricin-type beta-trefoil lectin domain
1111116Inhibitor of Apoptosis domain
43333319Voltage gated chloride channel
22232213Caspase domain
1010949951GDSL-like Lipase/Acylhydrolase
1111116Poly-adenylate binding protein, unique domain
111115POLO box duplicated region
201917181818110ABC transporter transmembrane region
55555530FAD binding domain
33333318Condensation domain
2111117S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1111116HAMP domain
22222212ribosomal L5P family C-terminus
65565532Insulinase (Peptidase family M16)
33333318Dehydrogenase E1 component
1111116Lumazine binding domain
86556636Elongation factor G C-terminus
64444426HMGL-like
64444426DnaJ central domain
33333318Starch binding domain
22232213Ribosomal protein L1p/L10e family
77777742Cation transporting ATPase, C-terminus
88688846Cation transporter/ATPase, N-terminus
1111116dUTPase
44444424Aconitase C-terminal domain
43333319Amino acid kinase family
2111117N-(5'phosphoribosyl)anthranilate (PRA) isomerase
108998852Acyl transferase domain
2111117Urease beta subunit
44444424Dihydrodipicolinate synthetase family
292928153030161haloacid dehalogenase-like hydrolase
65555531Glycosyl hydrolases family 2
99101191058Glycosyl hydrolases family 18
1111116Proliferating cell nuclear antigen, N-terminal domain
11Translation initiation factor IF-3, C-terminal domain
1111116Acylphosphatase
1111116Adenylosuccinate synthetase
4111119Asparaginase, N-terminal
11114Beta defensin
33331114Peptidase S24-like
22222212Inorganic pyrophosphatase
13131315131380Glycosyl hydrolases family 16
22222212Glycosyl hydrolases family 15
33333318NADH:flavin oxidoreductase / NADH oxidase family
444444243-hydroxyacyl-CoA dehydrogenase, C-terminal domain
2211118Glycosyl hydrolase family 20, catalytic domain
66676637HhH-GPD superfamily base excision DNA repair protein
1111116AIR carboxylase
77697743GMC oxidoreductase
22122211Asparagine synthase
212119191819117Fungal cellulose binding domain
65665533Septin
1111116EF-1 guanine nucleotide exchange domain
1111116Homoserine dehydrogenase
66Flavin-binding monooxygenase-like
112LPXTG cell wall anchor motif
33332317tRNA synthetases class I (E and Q), catalytic domain
1111116tRNA synthetases class I (R)
43454424XPG N-terminal domain
139879955Metallo-beta-lactamase superfamily
22121210F5/8 type C domain
22222212Choline/Carnitine o-acyltransferase
1111116Putative esterase
1111116Ferrochelatase
42222214Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
2111117Arginosuccinate synthase
1111116Electron transfer flavoprotein FAD-binding domain
33333318RNB domain
44344423Dioxygenase
43333319CNH domain
32122212Diacylglycerol kinase catalytic domain
77587741Dual specificity phosphatase, catalytic domain
44
53223318P21-Rho-binding domain
16121213121277PX domain
43323318Ras association (RalGDS/AF-6) domain
65335527UBX domain
44454425VHS domain
1111116Phosphoinositide 3-kinase C2
22222212DAHP synthetase I family
119887750Carbon-nitrogen hydrolase
1111116N-acetyltransferase
2111117Prephenate dehydratase
74444427Syntaxin
112Pentapeptide repeats (8 copies)
85545532Pumilio-family RNA binding repeat
96665638Histone-like transcription factor (CBF/NF-Y) and archaeal histone
1111116Pterin binding enzyme
2212119ER lumen protein retaining receptor
3222211Glycoprotease family
1111116Histidinol dehydrogenase
54434424impB/mucB/samB family
111115
1111116Ribosomal L15
1113118Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal prokaryotic L21 protein
1111116Ribosomal L28 family
1111116Ribosomal L29 protein
1111116Ribosomal L39 protein
1111116Ribosomal S17
1111116Ribulose-phosphate 3 epimerase family
1111116Translationally controlled tumour protein
55455529Glycosyl hydrolase family 7
2111117RNA pseudouridylate synthase
44444424Histone deacetylase domain
1122118POT family
1111116PWWP domain
19181018171799SET domain
33232215Isochorismatase family
43133317Permease family
1111116Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
55554428XPG I-region
1111116Acetokinase family
22212211DNA photolyase
111115Nitroreductase family
33233317Sulfatase
11111166,7-dimethyl-8-ribityllumazine synthase
1111116Ribosomal protein S16
22222212Acyl CoA binding protein
54344424Cullin family
99378844FAD binding domain
87767742O-methyltransferase domain
44124419EamA-like transporter family
111115
138888853ThiF family
1111116Ribosomal family S4e
33333318Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
44444424Ammonium Transporter Family
54444425Sulfate permease family
1111116MATH domain
112Gastrin/cholecystokinin family
22222212Dehydratase family
22222212Transaldolase/Fructose-6-phosphate aldolase
22222212Mechanosensitive ion channel
11222210GTP cyclohydrolase II
11111163,4-dihydroxy-2-butanone 4-phosphate synthase
44344423Adaptor complexes medium subunit family
87576639Exonuclease
1111116Dipeptidyl peptidase IV (DPP IV) N-terminal region
33NB-ARC domain
1110910101060Glycosyl hydrolase family 3 N terminal domain
1111116Ribosomal protein L44
1111116Sodium:sulfate symporter transmembrane region
1111116DNA-dependent RNA polymerase
1111116FAD binding domain in molybdopterin dehydrogenase
1111116Glycosyl transferase family 4
22222212HCO3- transporter family
22222212Nucleosome assembly protein (NAP)
44343422Synaptobrevin
1111116GMP synthase C terminal domain
22LAGLIDADG endonuclease
54444425Adenosine/AMP deaminase
91078101054Oxidoreductase FAD-binding domain
1111116Thioesterase domain
42222214Histidine biosynthesis protein
33334420Glycosyltransferase family 20
32222213UDP-glucose/GDP-mannose dehydrogenase family, central domain
32222213Carbamoyl-phosphate synthase small chain, CPSase domain
33112212PAS fold
43233318Probable molybdopterin binding domain
44444424Sec1 family
22222212GDP dissociation inhibitor
55255527Sodium/hydrogen exchanger family
22122211RNA polymerase Rpb3/RpoA insert domain
55554428Initiation factor 2 subunit family
22122211Electron transfer flavoprotein domain
1111116Uricase
1111116Ribosomal S3Ae family
1111116Ribosomal L27 protein
113