PFAM Domains • Exophiala alcalophila J33 v1.0
Annotations/GenomesAspni7Exoalc1Exoalc1_J33Gymci1_1Monpu1Phach1TotalAnnotation Description
PFAMs
10,16011,47811,4017,1557,2856,46553,944
117 transmembrane receptor (rhodopsin family)
453838384341243ATPase family associated with various cellular activities (AAA)
634645414235272ABC transporter
44444424ATP synthase alpha/beta family, nucleotide-binding domain
11EGF-like domain
14171614141489Elongation factor Tu GTP binding domain
9119810855Helix-loop-helix DNA-binding domain
46683229Hsp20/alpha crystallin family
79977746Hsp70 protein
87888948KH domain
11114SH2 domain
241515232220119SH3 domain
9101010101059Actin
878101173135288Ankyrin repeat
2421110PAN domain
77777540ADP-ribosylation factor family
121111691261Eukaryotic aspartyl protease
54444425Cyclic nucleotide-binding domain
1111116Cytochrome c
2211219Double-stranded RNA binding motif
192217171976EF hand
111254Fe-4S binding domain
31122211Fibronectin type III domain
21115Globin
192020109684Glutathione S-transferase, C-terminal domain
2111128Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
83388232Homeodomain
44425322lactate/malate dehydrogenase, NAD binding domain
213Low-density lipoprotein receptor repeat class B
55544528Myosin head (motor domain)
147127129603645544Cytochrome P450
13111411713211496704Protein kinase domain
16171610131587Pyridine nucleotide-disulphide oxidoreductase
232424242320138Ras family
14171710101987Response regulator receiver domain
51151114RNase H
645858616255358RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
11Serpin (serine protease inhibitor)
33311213Copper/zinc superoxide dismutase (SODC)
22222111Iron/manganese superoxide dismutases, alpha-hairpin domain
54545326Subtilase family
99129125374363496Sugar (and other) transporter
11101099857Thioredoxin
11114Trypsin
44454425Tubulin/FtsZ family, GTPase domain
1113129von Willebrand factor type A domain
692425495223242Zinc finger, C2H2 type
4367444124165Zinc finger, C3HC4 type (RING finger)
243122629Zinc knuckle
32222213Protein-tyrosine phosphatase
155208213616966772short chain dehydrogenase
1189092383940417Zinc-binding dehydrogenase
68876540Thiolase, N-terminal domain
5055913991Beta-ketoacyl synthase, N-terminal domain
644565302Fe-2S iron-sulfur cluster binding domain
1112218Enolase, C-terminal TIM barrel domain
97898748Glutamine amidotransferase class-I
910101091058TCP-1/cpn60 chaperonin family
11ATP synthase A chain
43333521Glutamine synthetase, catalytic domain
22222111Triosephosphate isomerase
182624141512109E1-E2 ATPase
77797643Core histone H2A/H2B/H3/H4
1510105131871Alpha amylase, catalytic domain
12223212Phorbol esters/diacylglycerol binding domain (C1 domain)
97779746Bacterial transferase hexapeptide (six repeats)
35533322tRNA synthetases class I (I, L, M and V)
78878442Cyclin, N-terminal domain
462018121212120Carboxylesterase family
44444424DNA polymerase family B
54434323ATP synthase subunit C
35532422Peroxidase
11161568561Beta-lactamase
24332115C-5 cytosine-specific DNA methylase
312826262622159Calcineurin-like phosphoesterase
888541245Cellulase (glycosyl hydrolase family 5)
77777843tRNA synthetases class II (D, K and N)
393939363633222Mitochondrial carrier protein
112recA bacterial DNA recombination protein
301919171812115Aminotransferase class I and II
10441010846Phosphoribosyl transferase domain
10101010101060Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
1111116Phosphoglycerate kinase
22211210Ribosomal protein S4/S9 N-terminal domain
22222212Ribosomal protein S12/S23
2114Bacterial regulatory helix-turn-helix proteins, AraC family
1111116Chaperonin 10 Kd subunit
98812101259C2 domain
15101015181583PH domain
11181989974bZIP transcription factor
324948152622192Aldehyde dehydrogenase family
344346347119187321,375Fungal Zn(2)-Cys(6) binuclear cluster domain
272728232118144Cytochrome b5-like Heme/Steroid binding domain
56622425Oxidoreductase molybdopterin binding domain
23161512151192Oxidoreductase NAD-binding domain
292524252424151SNF2 family N-terminal domain
22222212Ribosomal protein S7p/S5e
232221212116124Ubiquitin-conjugating enzyme
88866642Isocitrate/isopropylmalate dehydrogenase
22222212Ribosomal Proteins L2, RNA binding domain
1111116Hsp90 protein
22222212Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
1111116Dihydrofolate reductase
56112Chitin recognition protein
25422318Cysteine-rich secretory protein family
1111116Ribosomal protein S3, C-terminal domain
4661522Cupin
31132212Annexin
12216Eukaryotic-type carbonic anhydrase
1113Chalcone and stilbene synthases, N-terminal domain
444433222-oxoacid dehydrogenases acyltransferase (catalytic domain)
95535431Catalase
211116Disintegrin
244111UDP-glucoronosyl and UDP-glucosyl transferase
8121087954Aminotransferase class-III
22222111Ribosomal protein S19
1111116DNA gyrase B
9111169551Thiamine pyrophosphate enzyme, central domain
56633427Lyase
22222212Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
2226Sodium:neurotransmitter symporter family
1221118Adenylate and Guanylate cyclase catalytic domain
1111116ATP synthase delta (OSCP) subunit
2111117Orotidine 5'-phosphate decarboxylase / HUMPS family
1111116Indole-3-glycerol phosphate synthase
33Aromatic amino acid lyase
1111116Pyruvate kinase, barrel domain
11131110101065Kinesin motor domain
272424282724154DnaJ domain
14141414141484Proteasome subunit
7101024841Major intrinsic protein
1111116ATP synthase
311229Glycosyl hydrolase family 1
11111163'5'-cyclic nucleotide phosphodiesterase
1111116Profilin
1221118Ribosomal protein L22p/L17e
22222111Ribosomal protein L14p/L23e
810101110958Ubiquitin family
54444324Cofilin/tropomyosin-type actin-binding protein
2332221414-3-3 protein
22263318Alkaline phosphatase
111317Zinc carboxypeptidase
393737172722179Aldo/keto reductase family
134516131566Myb-like DNA-binding domain
44444323Forkhead domain
443213Glycosyl hydrolases family 32 N-terminal domain
1221118Ribosomal protein L16p/L10e
22212110Ribosomal protein S14p/S29e
43333218FKBP-type peptidyl-prolyl cis-trans isomerase
1111116Glutathione peroxidase
12216
108866644Flavodoxin
1111116Calreticulin family
85531123Common central domain of tyrosinase
109975646Aminotransferase class-V
1111116Ribonucleotide reductase, small chain
394444383838241DEAD/DEAH box helicase
757170737473436Helicase conserved C-terminal domain
1111116EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
22222212Ribosomal protein L23
1112218Pyridoxal-dependent decarboxylase, C-terminal sheet domain
1111116Ribosomal protein L5
95566738Pyridoxal-dependent decarboxylase conserved domain
43323217Citrate synthase, C-terminal domain
55565531GHMP kinases N terminal domain
7121268651Biotin carboxylase, N-terminal domain
3111118Tryptophan synthase alpha chain
16141412121280Pyridoxal-phosphate dependent enzyme
15141416131284NUDIX domain
44455325pfkB family carbohydrate kinase
21111933Glycosyl hydrolases family 28
1992324Luciferase-like monooxygenase
22222212Ribosomal protein L3
22222212Ribosomal protein L11, RNA binding domain
13141498967Histidine phosphatase superfamily (branch 1)
1111116Thymidylate synthase
112Lipoxygenase
44444424ATP synthase alpha/beta chain, C terminal domain
55555530Calponin homology (CH) domain
62254524Glutamine amidotransferases class-II
22222212Ribosomal protein S15
1113Thaumatin family
1111116Fructose-1-6-bisphosphatase, N-terminal domain
111115Ribonucleotide reductase, all-alpha domain
22222212Ribosomal protein S2
42222113SRF-type transcription factor (DNA-binding and dimerisation domain)
77754434GATA zinc finger
632828393943240Amino acid permease
76643329Prolyl oligopeptidase family
22212110Ribosomal protein L30p/L7e
139979855Histidine phosphatase superfamily (branch 2)
1111116Respiratory-chain NADH dehydrogenase, 30 Kd subunit
77745333Aconitase family (aconitate hydratase)
2112118Glycosyl hydrolase family 10
52232418Glycosyl hydrolases family 17
22212110Ribosomal protein S5, N-terminal domain
1111116Nucleoside diphosphate kinase
2114Tetraspanin family
22222212Ribosomal protein S10p/S20e
117644335Arrestin (or S-antigen), N-terminal domain
1111116Phosphoglucose isomerase
1111116Carbohydrate phosphorylase
111115SecY translocase
1111116Respiratory-chain NADH dehydrogenase, 49 Kd subunit
22222212Ribosomal protein L6
113363329Polyprenyl synthetase
64446428Hexokinase
998107649Dynamin family
1111116Transcription factor TFIID (or TATA-binding protein, TBP)
99926338Rieske [2Fe-2S] domain
11114Phytochrome region
9151588863Biotin-requiring enzyme
1111116Phosphofructokinase
1222119Ribosomal protein S17
4111119Hydroxymethylglutaryl-coenzyme A reductase
35545426FGGY family of carbohydrate kinases, N-terminal domain
1113Sodium:dicarboxylate symporter family
102828148593Enoyl-CoA hydratase/isomerase
22222212Ribosomal protein S9/S16
22222212Transcription factor TFIIB repeat
6101078344Cytidine and deoxycytidylate deaminase zinc-binding region
1111217Molybdopterin oxidoreductase
43245523Chromo (CHRromatin Organisation MOdifier) domain
23321213Phosphatidylinositol-specific phospholipase C, Y domain
34431318Phosphatidylinositol-specific phospholipase C, X domain
111010791057D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
22213212Malic enzyme, N-terminal domain
112PEP-utilising enzyme, mobile domain
211222106-phosphogluconate dehydrogenase, C-terminal domain
14141418960Multicopper oxidase
99101010957WW domain
1111217Ribosomal RNA adenine dimethylase
3317Yeast PIR protein repeat
119989811410889626WD domain, G-beta repeat
37757433Heavy-metal-associated domain
33333217Adenylate kinase
22232213Phosphoglucomutase/phosphomannomutase, C-terminal domain
22222111Ribosomal protein S8
1111116Ribosomal protein S11
44444121LIM domain
11Matrixin
32242114Regulator of chromosome condensation (RCC1) repeat
21122210Ribosomal protein S13/S18
42232215chorismate binding enzyme
3333321760s Acidic ribosomal protein
84444428Prenyltransferase and squalene oxidase repeat
54477633Protein kinase C terminal domain
1111116Single-strand binding protein family
1111116S-adenosylmethionine synthetase, N-terminal domain
77777641Bromodomain
921211313683Acyl-CoA dehydrogenase, C-terminal domain
15151516151490Ubiquitin carboxyl-terminal hydrolase
1113Ribosomal protein L36
22212211Ribonuclease T2 family
43333319HSF-type DNA-binding
22222212SRP54-type protein, GTPase domain
1111116Urease alpha-subunit, N-terminal domain
128836744Serine carboxypeptidase
77777742Phosphatidylinositol 3- and 4-kinase
3111219Transketolase, thiamine diphosphate binding domain
311218Glycosyl hydrolases family 11
54433221Inositol monophosphatase family
44444323Glutaredoxin
72255425Isocitrate lyase family
22222212Serine hydroxymethyltransferase
66643227Iron-containing alcohol dehydrogenase
22212211Ribosomal protein L10
42243520KOW motif
1113Ribosomal protein L34
33322114RF-1 domain
4111115840Sodium:solute symporter family
1111116Imidazoleglycerol-phosphate dehydratase
1112117DNA polymerase family A
1111116IMP dehydrogenase / GMP reductase domain
1111116Glucose-6-phosphate dehydrogenase, NAD binding domain
75566635Protein phosphatase 2C
23332215Nucleotidyl transferase
36613120Carbonic anhydrase
1221118Phosphoribulokinase / Uridine kinase family
84455430Fatty acid desaturase
56664633MutS domain V
1111217Delta-aminolevulinic acid dehydratase
68845637Arginase family
66666636MCM P-loop domain
33311112Squalene/phytoene synthase
81011710854FHA domain
787170443932334AMP-binding enzyme
44433321G-protein alpha subunit
76666839HMG (high mobility group) box
101313651360His Kinase A (phospho-acceptor) domain
32223315Armadillo/beta-catenin-like repeat
291515242323129Tetratricopeptide repeat
24322316Ion transport protein
1111116DNA gyrase/topoisomerase IV, subunit A
128710111058BRCA1 C Terminus (BRCT) domain
1366571350Glycosyl transferases group 1
42245421Glycosyl transferase family 2
1212118SAM domain (Sterile alpha motif)
1111116linker histone H1 and H5 family
1111116Ribosomal protein L7/L12 C-terminal domain
731112Pectate lyase
3115ribonuclease
1111116Urease, gamma subunit
44445425CoA-ligase
571010141811120Phosphopantetheine attachment site
33323216Formyl transferase
119999855Metallopeptidase family M24
131114161257Leucine Rich Repeat
501514242731161alpha/beta hydrolase fold
33333318RNA polymerase Rpb2, domain 6
44444323PB1 domain
22222212Staphylococcal nuclease homologue
1111111011963Rab-GTPase-TBC domain
1111116Tudor domain
1111116WH1 domain
44444323Zinc finger, ZZ type
12222110HRDC domain
97789848CBS domain
32222213Ribosomal protein L13
22222212Ribosomal protein L4/L1 family
1111116Clp protease
34443321S1 RNA binding domain
1111116HIUase/Transthyretin family
42223316AhpC/TSA family
44444424tRNA synthetases class I (W and Y)
123UvrD/REP helicase N-terminal domain
510763435Rhodanese-like domain
22222212Universal stress protein family
342727303417169Acetyltransferase (GNAT) family
111115SecE/Sec61-gamma subunits of protein translocation complex
1111116C-terminal regulatory domain of Threonine dehydratase
22222212AIR synthase related protein, N-terminal domain
96688744tRNA synthetase class II core domain (G, H, P, S and T)
1111116SpoU rRNA Methylase family
22222212Tetrapyrrole (Corrin/Porphyrin) Methylases
1111116Glycosyl transferase family, a/b domain
2111117PDZ domain
5111035943Class II Aldolase and Adducin N-terminal domain
11Influenza non-structural protein (NS1)
34444423Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
55555429Fes/CIP4, and EFC/F-BAR homology domain
62246424IQ calmodulin-binding motif
22222212Phosphoinositide 3-kinase family, accessory domain (PIK domain)
53355324Phospholipase D Active site motif
15512115Regulator of G protein signaling domain
33333318GTPase-activator protein for Ras-like GTPase
54444425RasGEF domain
54444425RasGEF N-terminal motif
77777742RhoGAP domain
66666535RhoGEF domain
23322214SPRY domain
33333318RNA polymerase Rpb1, domain 2
2111117Guanylate kinase
53344423Gelsolin repeat
87777844UBA/TS-N domain
18131316181189PHD-finger
11114GGL domain
66666636HECT-domain (ubiquitin-transferase)
2111218Helix-hairpin-helix motif
1111116MSP (Major sperm protein) domain
72355325Ribonuclease III domain
35533221Region in Clathrin and VPS
22223314RanBP1 domain
22122211PPIC-type PPIASE domain
32223214Zn-finger in Ran binding protein and others
14882015873Zinc finger C-x8-C-x5-C-x3-H type (and similar)
22221211Poly(ADP-ribose) polymerase catalytic domain
1111116Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
631715813818232F-box domain
1111116Elongation factor 1 gamma, conserved domain
23312213Calpain family cysteine protease
2122310Copper fist DNA binding domain
75575534CRAL/TRIO domain
81718155669BTB/POZ domain
11Ricin-type beta-trefoil lectin domain
1111116Inhibitor of Apoptosis domain
33333318Voltage gated chloride channel
42212112Caspase domain
763420GDSL-like Lipase/Acylhydrolase
1111116Poly-adenylate binding protein, unique domain
331817152317123ABC transporter transmembrane region
89845640FAD binding domain
26331110659Condensation domain
1111116S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1111116HAMP domain
22222212ribosomal L5P family C-terminus
76666435Insulinase (Peptidase family M16)
54433322Dehydrogenase E1 component
1111116Lumazine binding domain
66666636Elongation factor G C-terminus
55545529HMGL-like
44444424DnaJ central domain
211127Starch binding domain
23322214Ribosomal protein L1p/L10e family
10121186653Cation transporting ATPase, C-terminus
14131399765Cation transporter/ATPase, N-terminus
2112118dUTPase
77745333Aconitase C-terminal domain
44433321Amino acid kinase family
1111116N-(5'phosphoribosyl)anthranilate (PRA) isomerase
4955810885Acyl transferase domain
1111116Urease beta subunit
72245626Dihydrodipicolinate synthetase family
442320303228177haloacid dehalogenase-like hydrolase
54422219Glycosyl hydrolases family 2
1554196453Glycosyl hydrolases family 18
1111116Proliferating cell nuclear antigen, N-terminal domain
112Translation initiation factor IF-3, C-terminal domain
11114Acylphosphatase
1111116Adenylosuccinate synthetase
22212110Asparaginase, N-terminal
33Beta defensin
32222112Peptidase S24-like
1221118Inorganic pyrophosphatase
7171664555Glycosyl hydrolases family 16
22223415Glycosyl hydrolases family 15
18141547866NADH:flavin oxidoreductase / NADH oxidase family
933341233-hydroxyacyl-CoA dehydrogenase, C-terminal domain
32231213Glycosyl hydrolase family 20, catalytic domain
36654630HhH-GPD superfamily base excision DNA repair protein
1111116AIR carboxylase
312424121310114GMC oxidoreductase
32222213Asparagine synthase
8322217Fungal cellulose binding domain
56665533Septin
1111116EF-1 guanine nucleotide exchange domain
1111116Homoserine dehydrogenase
391032229Flavin-binding monooxygenase-like
33343319tRNA synthetases class I (E and Q), catalytic domain
1221129tRNA synthetases class I (R)
44445425XPG N-terminal domain
1427281311497Metallo-beta-lactamase superfamily
11F5/8 type C domain
22232213Choline/Carnitine o-acyltransferase
222118Putative esterase
1111116Ferrochelatase
22222212Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
211116Arginosuccinate synthase
1111116Electron transfer flavoprotein FAD-binding domain
33333318RNB domain
133343834Dioxygenase
23323316CNH domain
12222211Diacylglycerol kinase catalytic domain
78868643Dual specificity phosphatase, catalytic domain
22222212P21-Rho-binding domain
14141415141182PX domain
23332417Ras association (RalGDS/AF-6) domain
56655532UBX domain
34444423VHS domain
1111116Phosphoinositide 3-kinase C2
22222212DAHP synthetase I family
151413109869Carbon-nitrogen hydrolase
53311114N-acetyltransferase
111115Prephenate dehydratase
33353421Syntaxin
54455528Pumilio-family RNA binding repeat
66666636Histone-like transcription factor (CBF/NF-Y) and archaeal histone
1111116Pterin binding enzyme
2221119ER lumen protein retaining receptor
22222212Glycoprotease family
22211210Histidinol dehydrogenase
44444424impB/mucB/samB family
11114
1111116Ribosomal L15
13311110Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
1111116Ribosomal L28 family
1111116Ribosomal L29 protein
111115Ribosomal L39 protein
1111116Ribosomal S17
1111116Ribulose-phosphate 3 epimerase family
1111116Translationally controlled tumour protein
2327Glycosyl hydrolase family 7
6612Ring hydroxylating alpha subunit (catalytic domain)
1111116RNA pseudouridylate synthase
45544426Histone deacetylase domain
45547227POT family
1111116PWWP domain
1617181591085SET domain
13151566459Isochorismatase family
35514321Permease family
1111116Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
44444424XPG I-region
1111116Acetokinase family
244313DNA photolyase
112NlpC/P60 family
11Cation-independent mannose-6-phosphate receptor repeat
1225Nitroreductase family
1188581050Sulfatase
11111166,7-dimethyl-8-ribityllumazine synthase
111115Ribosomal protein S16
32221111Acyl CoA binding protein
44444424Cullin family
116878545FAD binding domain
255535952O-methyltransferase domain
53353423EamA-like transporter family
22228
88888848ThiF family
1111116Ribosomal family S4e
8111165243Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
48825633Ammonium Transporter Family
57733328Sulfate permease family
1221118MATH domain
74435225Dehydratase family
2111139Transaldolase/Fructose-6-phosphate aldolase
23321213Mechanosensitive ion channel
13311211GTP cyclohydrolase II
1111153,4-dihydroxy-2-butanone 4-phosphate synthase
44443423Adaptor complexes medium subunit family
95577639Exonuclease
1113118Dipeptidyl peptidase IV (DPP IV) N-terminal region
15511NB-ARC domain
19871171264Glycosyl hydrolase family 3 N terminal domain
1111116Ribosomal protein L44
112Sodium:sulfate symporter transmembrane region
1111116DNA-dependent RNA polymerase
21122210FAD binding domain in molybdopterin dehydrogenase
11Peptidase S7, Flavivirus NS3 serine protease
111115Glycosyl transferase family 4
31122312HCO3- transporter family
22212110Nucleosome assembly protein (NAP)
44444323Synaptobrevin
1111116GMP synthase C terminal domain
22Phage lysozyme
56645632Adenosine/AMP deaminase
147789651Oxidoreductase FAD-binding domain
92221319Thioesterase domain
22222212Histidine biosynthesis protein
64436326Glycosyltransferase family 20
333211UDP-glucose/GDP-mannose dehydrogenase family, central domain
21222211Carbamoyl-phosphate synthase small chain, CPSase domain
31116PAS fold
22223112Probable molybdopterin binding domain
44444424Sec1 family
22222212GDP dissociation inhibitor
77767539Sodium/hydrogen exchanger family
22222212RNA polymerase Rpb3/RpoA insert domain
55555530Initiation factor 2 subunit family
1214PQQ enzyme repeat
22222212Electron transfer flavoprotein domain
2111117Uricase
1111116Ribosomal S3Ae family
1111116Ribosomal L27 protein
1111116GTP1/OBG
32222213Gamma-glutamyltranspeptidase
1113Ribosomal L40e family
1111116GrpE
42223215TatD related DNase
1221118Inhibitor of apoptosis-promoting Bax1
1111116Eukaryotic DNA topoisomerase I, catalytic core
46