PFAM Domains • Melanomma pulvis-pyrius v1.0
Annotations/GenomesAltbr1CocheC5_3Dotse1Hyspu1Melpu1Mycgr3Sepmu1TotalAnnotation Description
PFAMs
5,9039,2958,1109,01610,4996,4207,52756,770
1127 transmembrane receptor (rhodopsin family)
32414562524241315ATPase family associated with various cellular activities (AAA)
37423247544332287ABC transporter
444444428ATP synthase alpha/beta family, nucleotide-binding domain
11EGF-like domain
1314141314141496Elongation factor Tu GTP binding domain
1113141010101381Helix-loop-helix DNA-binding domain
132332216Hsp20/alpha crystallin family
687797751Hsp70 protein
888989959KH domain
11Ribulose bisphosphate carboxylase large chain, catalytic domain
11111117SH2 domain
21222123232323156SH3 domain
9101010117966Actin
3588371001364131468Ankyrin repeat
4862414139PAN domain
777687749ADP-ribosylation factor family
822101211191193Eukaryotic aspartyl protease
244444426Cyclic nucleotide-binding domain
22Cytochrome b(C-terminal)/b6/petD
213Cytochrome b/b6/petB
11111117Cytochrome c
211112311Double-stranded RNA binding motif
18181718202019130EF hand
211211194Fe-4S binding domain
243263424Fibronectin type III domain
1111116Globin
1092117191614106Glutathione S-transferase, C-terminal domain
11111117Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
5861073544Homeodomain
442242321lactate/malate dehydrogenase, NAD binding domain
655555435Myosin head (motor domain)
63156781581857374787Cytochrome P450
84115105147171113118853Protein kinase domain
9171622221513114Pyridine nucleotide-disulphide oxidoreductase
22262427262423172Ras family
21272518222222157Response regulator receiver domain
2104513227RNase H
49586561635759412RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
314Reverse transcriptase (RNA-dependent DNA polymerase)
123232215Copper/zinc superoxide dismutase (SODC)
222222214Iron/manganese superoxide dismutases, alpha-hairpin domain
712411179666Subtilase family
74705578969351517Sugar (and other) transporter
1013121212101079Thioredoxin
522131115Trypsin
444444327Tubulin/FtsZ family, GTPase domain
154431321von Willebrand factor type A domain
56686154806246427Zinc finger, C2H2 type
35545273683948369Zinc finger, C3HC4 type (RING finger)
16123855352Zinc knuckle
222222214Protein-tyrosine phosphatase
9813213317223112498988short chain dehydrogenase
526960751016849474Zinc-binding dehydrogenase
976667647Thiolase, N-terminal domain
10281029461413150Beta-ketoacyl synthase, N-terminal domain
4646646362Fe-2S iron-sulfur cluster binding domain
112Papain family cysteine protease
11121118Enolase, C-terminal TIM barrel domain
11Cytochrome C and Quinol oxidase polypeptide I
78108108859Glutamine amidotransferase class-I
1010101010101070TCP-1/cpn60 chaperonin family
332442220Glutamine synthetase, catalytic domain
222222214Triosephosphate isomerase
1319101318131298E1-E2 ATPase
51177862872Core histone H2A/H2B/H3/H4
112Copper binding proteins, plastocyanin/azurin family
6611913131270Alpha amylase, catalytic domain
21322212Phorbol esters/diacylglycerol binding domain (C1 domain)
687589952Bacterial transferase hexapeptide (six repeats)
734456534tRNA synthetases class I (I, L, M and V)
596677646Cyclin, N-terminal domain
24291728401716171Carboxylesterase family
444444428DNA polymerase family B
344445428ATP synthase subunit C
11Legume lectin domain
784574338Peroxidase
8710192610686Beta-lactamase
223231316C-5 cytosine-specific DNA methylase
23282731302720186Calcineurin-like phosphoesterase
109816154567Cellulase (glycosyl hydrolase family 5)
7771087753tRNA synthetases class II (D, K and N)
36413837414038271Mitochondrial carrier protein
11recA bacterial DNA recombination protein
7171515221315104Aminotransferase class I and II
6898991059Phosphoribosyl transferase domain
1113121110121281Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
11111117Phosphoglycerate kinase
221221111Ribosomal protein S4/S9 N-terminal domain
222122213Ribosomal protein S12/S23
21115Bacterial regulatory helix-turn-helix proteins, AraC family
11111117Chaperonin 10 Kd subunit
1112141110131384C2 domain
16221817211717128PH domain
6998118859bZIP transcription factor
20272220241815146Aldehyde dehydrogenase family
79192152912901041231,031Fungal Zn(2)-Cys(6) binuclear cluster domain
18242620252423160Cytochrome b5-like Heme/Steroid binding domain
347335530Oxidoreductase molybdopterin binding domain
9181912171214101Oxidoreductase NAD-binding domain
21252327302622174SNF2 family N-terminal domain
222222214Ribosomal protein S7p/S5e
21222625242423165Ubiquitin-conjugating enzyme
778679852Isocitrate/isopropylmalate dehydrogenase
222222214Ribosomal Proteins L2, RNA binding domain
11111117Hsp90 protein
122222213Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
11111117Dihydrofolate reductase
9102411137Chitin recognition protein
313354524Cysteine-rich secretory protein family
21111118Ribosomal protein S3, C-terminal domain
343746330Cupin
122222213Annexin
1112229Eukaryotic-type carbonic anhydrase
111115Chalcone and stilbene synthases, N-terminal domain
2433333212-oxoacid dehydrogenases acyltransferase (catalytic domain)
446643431Catalase
11111117Disintegrin
22UDP-glucoronosyl and UDP-glucosyl transferase
6109789857Aminotransferase class-III
122222213Ribosomal protein S19
11111117DNA gyrase B
468994545Thiamine pyrophosphate enzyme, central domain
444445328Lyase
122222213Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
11114Sodium:neurotransmitter symporter family
1111116Adenylate and Guanylate cyclase catalytic domain
1111116ATP synthase delta (OSCP) subunit
11111117Orotidine 5'-phosphate decarboxylase / HUMPS family
11111117Indole-3-glycerol phosphate synthase
11Neurohypophysial hormones, N-terminal Domain
11125Aromatic amino acid lyase
11111117Pyruvate kinase, barrel domain
1011101311111076Kinesin motor domain
30292638312828210DnaJ domain
1214141414141496Proteasome subunit
77115610955Major intrinsic protein
11111117ATP synthase
23233215Glycosyl hydrolase family 1
11111163'5'-cyclic nucleotide phosphodiesterase
1211117Profilin
21111118Ribosomal protein L22p/L17e
222222214Ribosomal protein L14p/L23e
1011161610101083Ubiquitin family
254452426Cofilin/tropomyosin-type actin-binding protein
32222221514-3-3 protein
563563432Alkaline phosphatase
1083363336Zinc carboxypeptidase
22252835392221192Aldo/keto reductase family
1115151713121699Myb-like DNA-binding domain
245546430Forkhead domain
232124317Glycosyl hydrolases family 32 N-terminal domain
11111117Ribosomal protein L16p/L10e
13221211Ribosomal protein S14p/S29e
554444430FKBP-type peptidyl-prolyl cis-trans isomerase
11111117Glutathione peroxidase
112312212
6987108654Flavodoxin
112Protamine P1
1111116Calreticulin family
8128131571174Common central domain of tyrosinase
3899104952Aminotransferase class-V
11111117Ribonucleotide reductase, small chain
44393938404640286DEAD/DEAH box helicase
65777376777273513Helicase conserved C-terminal domain
11111117EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
222222214Ribosomal protein L23
1111217Pyridoxal-dependent decarboxylase, C-terminal sheet domain
222122213Ribosomal protein L5
665787544Pyridoxal-dependent decarboxylase conserved domain
233223217Citrate synthase, C-terminal domain
555565536GHMP kinases N terminal domain
777676747Biotin carboxylase, N-terminal domain
11111117Tryptophan synthase alpha chain
814101110111175Pyridoxal-phosphate dependent enzyme
11161418141513101NUDIX domain
554455634pfkB family carbohydrate kinase
654772536Glycosyl hydrolases family 28
1111228Luciferase-like monooxygenase
322222215Ribosomal protein L3
122221212Ribosomal protein L11, RNA binding domain
1015151515111495Histidine phosphatase superfamily (branch 1)
11111117Thymidylate synthase
1111116Lipoxygenase
444444428ATP synthase alpha/beta chain, C terminal domain
555455534Calponin homology (CH) domain
676444435Glutamine amidotransferases class-II
132222214Ribosomal protein S15
11111117Thaumatin family
221221111Fructose-1-6-bisphosphatase, N-terminal domain
11111117Ribonucleotide reductase, all-alpha domain
232222215Ribosomal protein S2
222213315SRF-type transcription factor (DNA-binding and dimerisation domain)
577378845GATA zinc finger
22393554563338277Amino acid permease
283362529Prolyl oligopeptidase family
231231113Ribosomal protein L30p/L7e
6121011137968Histidine phosphatase superfamily (branch 2)
11111117Respiratory-chain NADH dehydrogenase, 30 Kd subunit
445445430Aconitase family (aconitate hydratase)
55134220Glycosyl hydrolase family 10
126531624Glycosyl hydrolases family 17
222222214Ribosomal protein S5, N-terminal domain
11111117Nucleoside diphosphate kinase
112Tetraspanin family
21111219Ribosomal protein S10p/S20e
342472224Arrestin (or S-antigen), N-terminal domain
11111117Phosphoglucose isomerase
11111117Carbohydrate phosphorylase
11111117SecY translocase
11111117Respiratory-chain NADH dehydrogenase, 49 Kd subunit
222222214Ribosomal protein L6
583335431Polyprenyl synthetase
544543328Hexokinase
4757106645Dynamin family
11111218Transcription factor TFIID (or TATA-binding protein, TBP)
457455535Rieske [2Fe-2S] domain
77Proton-conducting membrane transporter
6119898960Biotin-requiring enzyme
11111117Phosphofructokinase
222222214Ribosomal protein S17
11111117Hydroxymethylglutaryl-coenzyme A reductase
334334424FGGY family of carbohydrate kinases, N-terminal domain
11114Sodium:dicarboxylate symporter family
812221115161397Enoyl-CoA hydratase/isomerase
222222214Ribosomal protein S9/S16
222222214Transcription factor TFIIB repeat
567878849Cytidine and deoxycytidylate deaminase zinc-binding region
21111118Molybdopterin oxidoreductase
455642531Chromo (CHRromatin Organisation MOdifier) domain
233233319Phosphatidylinositol-specific phospholipase C, Y domain
335235526Phosphatidylinositol-specific phospholipase C, X domain
99109126863D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
122222213Malic enzyme, N-terminal domain
1222121116-phosphogluconate dehydrogenase, C-terminal domain
5121320208886Multicopper oxidase
911810109865WW domain
11111117Ribosomal RNA adenine dimethylase
12632519Yeast PIR protein repeat
97127106107117104102760WD domain, G-beta repeat
643453429Heavy-metal-associated domain
444342324Adenylate kinase
322232115Phosphoglucomutase/phosphomannomutase, C-terminal domain
222121111Ribosomal protein S8
11122119Ribosomal protein S11
344354528LIM domain
1124Matrixin
11111218Regulator of chromosome condensation (RCC1) repeat
322122214Ribosomal protein S13/S18
22NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
222222214chorismate binding enzyme
44444332660s Acidic ribosomal protein
444454429Prenyltransferase and squalene oxidase repeat
567664741Protein kinase C terminal domain
1111116Single-strand binding protein family
11111117S-adenosylmethionine synthetase, N-terminal domain
678886750Bromodomain
14151615181511104Acyl-CoA dehydrogenase, C-terminal domain
15141515161517107Ubiquitin carboxyl-terminal hydrolase
11114Ribosomal protein L36
232222215Ribonuclease T2 family
243333321HSF-type DNA-binding
222222214SRP54-type protein, GTPase domain
11111117Urease alpha-subunit, N-terminal domain
913141613131189Serine carboxypeptidase
788888855Phosphatidylinositol 3- and 4-kinase
222322215Transketolase, thiamine diphosphate binding domain
452451122Glycosyl hydrolases family 11
554454431Inositol monophosphatase family
144442423Glutaredoxin
233552323Isocitrate lyase family
222222214Serine hydroxymethyltransferase
363544227Iron-containing alcohol dehydrogenase
122222213Ribosomal protein L10
533336225KOW motif
111115Ribosomal protein L34
11Negative factor, (F-Protein) or Nef
123222315RF-1 domain
134772327Sodium:solute symporter family
11111117Imidazoleglycerol-phosphate dehydratase
11111117DNA polymerase family A
11111117IMP dehydrogenase / GMP reductase domain
11111117Glucose-6-phosphate dehydrogenase, NAD binding domain
686666543Protein phosphatase 2C
232332217Nucleotidyl transferase
123542219Carbonic anhydrase
2111218Phosphoribulokinase / Uridine kinase family
6745116645Fatty acid desaturase
666666642MutS domain V
11111117Delta-aminolevulinic acid dehydratase
454554431Arginase family
676666643MCM P-loop domain
223232216Squalene/phytoene synthase
788695851FHA domain
11NADH-ubiquinone/plastoquinone oxidoreductase chain 6
34576449595148362AMP-binding enzyme
343454326G-protein alpha subunit
7771077752HMG (high mobility group) box
11NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
16222216191818131His Kinase A (phospho-acceptor) domain
132333217Armadillo/beta-catenin-like repeat
23312131322323184Tetratricopeptide repeat
223354322Ion transport protein
11111117DNA gyrase/topoisomerase IV, subunit A
101110111210872BRCA1 C Terminus (BRCT) domain
3671074744Glycosyl transferases group 1
455474736Glycosyl transferase family 2
631134119SAM domain (Sterile alpha motif)
11111117linker histone H1 and H5 family
12111118Ribosomal protein L7/L12 C-terminal domain
751152223Pectate lyase
12121119ribonuclease
1111116Urease, gamma subunit
354444428CoA-ligase
8291825301522147Phosphopantetheine attachment site
335334425Formyl transferase
5991198859Metallopeptidase family M24
13181217151614105Leucine Rich Repeat
22424653532333272alpha/beta hydrolase fold
333333321RNA polymerase Rpb2, domain 6
333343322PB1 domain
222122213Staphylococcal nuclease homologue
1212111111111179Rab-GTPase-TBC domain
11111117Tudor domain
11111117WH1 domain
335353325Zinc finger, ZZ type
331231114HRDC domain
881010991165CBS domain
222222214Ribosomal protein L13
222222214Ribosomal protein L4/L1 family
11111117Clp protease
243343423S1 RNA binding domain
111115HIUase/Transthyretin family
665556437AhpC/TSA family
444455430tRNA synthetases class I (W and Y)
11122119UvrD/REP helicase N-terminal domain
446555534Rhodanese-like domain
122122212Universal stress protein family
21453152552430258Acetyltransferase (GNAT) family
11111117SecE/Sec61-gamma subunits of protein translocation complex
11111117C-terminal regulatory domain of Threonine dehydratase
232222215AIR synthase related protein, N-terminal domain
897787753tRNA synthetase class II core domain (G, H, P, S and T)
222222214SpoU rRNA Methylase family
222222214Tetrapyrrole (Corrin/Porphyrin) Methylases
11111117Glycosyl transferase family, a/b domain
11211219PDZ domain
587795546Class II Aldolase and Adducin N-terminal domain
443432323Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
555544533Fes/CIP4, and EFC/F-BAR homology domain
665644435IQ calmodulin-binding motif
222222214Phosphoinositide 3-kinase family, accessory domain (PIK domain)
565564536Phospholipase D Active site motif
11111117Regulator of G protein signaling domain
233333320GTPase-activator protein for Ras-like GTPase
344444427RasGEF domain
244442424RasGEF N-terminal motif
798886854RhoGAP domain
666754640RhoGEF domain
224422218SPRY domain
333333321RNA polymerase Rpb1, domain 2
11112118Guanylate kinase
333344424Gelsolin repeat
881291161165UBA/TS-N domain
17172416201320127PHD-finger
111115GGL domain
456554635HECT-domain (ubiquitin-transferase)
222322215Helix-hairpin-helix motif
11111117MSP (Major sperm protein) domain
3105444535Ribonuclease III domain
121221211Region in Clathrin and VPS
222221213RanBP1 domain
222222214PPIC-type PPIASE domain
11211118Zn-finger in Ran binding protein and others
18171720221317124Zinc finger C-x8-C-x5-C-x3-H type (and similar)
123131213Poly(ADP-ribose) polymerase catalytic domain
211217Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
506956114967743505F-box domain
11111117Elongation factor 1 gamma, conserved domain
231332115Calpain family cysteine protease
212231213Copper fist DNA binding domain
555554534CRAL/TRIO domain
219173221411106BTB/POZ domain
112318Ricin-type beta-trefoil lectin domain
11111117Inhibitor of Apoptosis domain
334444426Voltage gated chloride channel
132231214Caspase domain
119813173667GDSL-like Lipase/Acylhydrolase
11111117Poly-adenylate binding protein, unique domain
111216POLO box duplicated region
11NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
19201624281915141ABC transporter transmembrane region
112Integrase core domain
4976115547FAD binding domain
511891081162Condensation domain
11111117S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1111116HAMP domain
222222214ribosomal L5P family C-terminus
556565436Insulinase (Peptidase family M16)
333333321Dehydrogenase E1 component
11111117Lumazine binding domain
466665639Elongation factor G C-terminus
447446635HMGL-like
244354426DnaJ central domain
224154422Starch binding domain
232232317Ribosomal protein L1p/L10e family
8105698753Cation transporting ATPase, C-terminus
91158108758Cation transporter/ATPase, N-terminus
1221219dUTPase
344445428Aconitase C-terminal domain
123443320Amino acid kinase family
11111117N-(5'phosphoribosyl)anthranilate (PRA) isomerase
926832411312141Acyl transferase domain
11111117Urease beta subunit
573683234Dihydrodipicolinate synthetase family
29382632373030222haloacid dehalogenase-like hydrolase
784477340Glycosyl hydrolases family 2
71699119566Glycosyl hydrolases family 18
1111116Proliferating cell nuclear antigen, N-terminal domain
1111116Acylphosphatase
11111117Adenylosuccinate synthetase
31132111Asparaginase, N-terminal
113312314Peptidase S24-like
11111117Inorganic pyrophosphatase
109810981064Glycosyl hydrolases family 16
222341317Glycosyl hydrolases family 15
7597910653NADH:flavin oxidoreductase / NADH oxidase family
2332242183-hydroxyacyl-CoA dehydrogenase, C-terminal domain
341541220Glycosyl hydrolase family 20, catalytic domain
344454327HhH-GPD superfamily base excision DNA repair protein
11111117AIR carboxylase
19292229311818166GMC oxidoreductase
243221216Asparagine synthase
9111109141Fungal cellulose binding domain
565665538Septin
21111118EF-1 guanine nucleotide exchange domain
11111117Homoserine dehydrogenase
133119Flavin-binding monooxygenase-like
133433320tRNA synthetases class I (E and Q), catalytic domain
221321112tRNA synthetases class I (R)
444353427XPG N-terminal domain
81317131581589Metallo-beta-lactamase superfamily
1111318F5/8 type C domain
122232214Choline/Carnitine o-acyltransferase
11111117Putative esterase
11111117Ferrochelatase
222222214Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
12111118Arginosuccinate synthase
11111117Electron transfer flavoprotein FAD-binding domain
333332320RNB domain
5746103843Dioxygenase
233332218CNH domain
112211210Diacylglycerol kinase catalytic domain
4891096854Dual specificity phosphatase, catalytic domain
6511
232331216P21-Rho-binding domain
1113111212111282PX domain
232232216Ras association (RalGDS/AF-6) domain
575664538UBX domain
444344427VHS domain
11111117Phosphoinositide 3-kinase C2
222222214DAHP synthetase I family
8131113169979Carbon-nitrogen hydrolase
113222213N-acetyltransferase
11111117Prephenate dehydratase
554543430Syntaxin
11Pentapeptide repeats (8 copies)
355555533Pumilio-family RNA binding repeat
576765541Histone-like transcription factor (CBF/NF-Y) and archaeal histone
11111117Pterin binding enzyme
222222214ER lumen protein retaining receptor
222222214Glycoprotease family
12111118Histidinol dehydrogenase
344445428impB/mucB/samB family
11111117
11111117Ribosomal L15
11111117Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
11111117Ribosomal L28 family
11111117Ribosomal L29 protein
1111116Ribosomal L39 protein
12111118Ribosomal S17
12111118Ribulose-phosphate 3 epimerase family
11111117Translationally controlled tumour protein
56147124Glycosyl hydrolase family 7
11111117RNA pseudouridylate synthase
444444428Histone deacetylase domain
583585438POT family
11111117PWWP domain
8171624181013106SET domain
61210161891081Isochorismatase family
351443424Permease family
11111117Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
556355534XPG I-region
11111117Acetokinase family
434234424DNA photolyase
112NlpC/P60 family
11Cation-independent mannose-6-phosphate receptor repeat
11Nitroreductase family
226554327Sulfatase
111111176,7-dimethyl-8-ribityllumazine synthase
1111116Ribosomal protein S16
122221212Acyl CoA binding protein
244453426Cullin family
2131315