PFAM Domains • Orbiliomycetes
Annotations/GenomesArtol1Monha1TotalAnnotation Description
PFAMs
7,5927,73115,323
2247 transmembrane receptor (rhodopsin family)
474390ATPase family associated with various cellular activities (AAA)
333467ABC transporter
549ATP synthase alpha/beta family, nucleotide-binding domain
141529Elongation factor Tu GTP binding domain
91019Helix-loop-helix DNA-binding domain
336Hsp20/alpha crystallin family
7714Hsp70 protein
9918KH domain
112SH2 domain
242549SH3 domain
101020Actin
149152301Ankyrin repeat
3710PAN domain
8917ADP-ribosylation factor family
263258Eukaryotic aspartyl protease
448Cyclic nucleotide-binding domain
112Cytochrome c
347Double-stranded RNA binding motif
181937EF hand
2244Fe-4S binding domain
224Fibronectin type III domain
112Globin
81220Glutathione S-transferase, C-terminal domain
112Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
6511Homeodomain
336lactate/malate dehydrogenase, NAD binding domain
5510Myosin head (motor domain)
364581Cytochrome P450
104111215Protein kinase domain
111122Pyridine nucleotide-disulphide oxidoreductase
262450Ras family
212142Response regulator receiver domain
5510RNase H
6766133RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
459Reverse transcriptase (RNA-dependent DNA polymerase)
224Copper/zinc superoxide dismutase (SODC)
336Iron/manganese superoxide dismutases, alpha-hairpin domain
404888Subtilase family
394180Sugar (and other) transporter
111223Thioredoxin
325Trypsin
448Tubulin/FtsZ family, GTPase domain
6713von Willebrand factor type A domain
6655121Zinc finger, C2H2 type
384179Zinc finger, C3HC4 type (RING finger)
131124Zinc knuckle
224Protein-tyrosine phosphatase
6072132short chain dehydrogenase
263056Zinc-binding dehydrogenase
5510Thiolase, N-terminal domain
6713Beta-ketoacyl synthase, N-terminal domain
4482Fe-2S iron-sulfur cluster binding domain
112Enolase, C-terminal TIM barrel domain
8816Glutamine amidotransferase class-I
91019TCP-1/cpn60 chaperonin family
347Glutamine synthetase, catalytic domain
112Triosephosphate isomerase
151530E1-E2 ATPase
9918Core histone H2A/H2B/H3/H4
22Copper binding proteins, plastocyanin/azurin family
549Alpha amylase, catalytic domain
224Phorbol esters/diacylglycerol binding domain (C1 domain)
11Metallothionein
8917Bacterial transferase hexapeptide (six repeats)
437tRNA synthetases class I (I, L, M and V)
8917Cyclin, N-terminal domain
162137Carboxylesterase family
448DNA polymerase family B
336ATP synthase subunit C
112Peroxidase
369Beta-lactamase
336C-5 cytosine-specific DNA methylase
242448Calcineurin-like phosphoesterase
191736Cellulase (glycosyl hydrolase family 5)
7714tRNA synthetases class II (D, K and N)
373774Mitochondrial carrier protein
112recA bacterial DNA recombination protein
151631Aminotransferase class I and II
8816Phosphoribosyl transferase domain
121224Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
123Ribosome inactivating protein
112Phosphoglycerate kinase
224Ribosomal protein S4/S9 N-terminal domain
224Ribosomal protein S12/S23
112Chaperonin 10 Kd subunit
151429C2 domain
192140PH domain
111021bZIP transcription factor
131225Aldehyde dehydrogenase family
8682168Fungal Zn(2)-Cys(6) binuclear cluster domain
201838Cytochrome b5-like Heme/Steroid binding domain
325Oxidoreductase molybdopterin binding domain
131326Oxidoreductase NAD-binding domain
252651SNF2 family N-terminal domain
224Ribosomal protein S7p/S5e
232548Ubiquitin-conjugating enzyme
6612Isocitrate/isopropylmalate dehydrogenase
224Ribosomal Proteins L2, RNA binding domain
112Hsp90 protein
224Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
628Chitin recognition protein
91120Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
336Cupin
448Annexin
235Eukaryotic-type carbonic anhydrase
112Chalcone and stilbene synthases, N-terminal domain
3362-oxoacid dehydrogenases acyltransferase (catalytic domain)
448Catalase
112Disintegrin
22UDP-glucoronosyl and UDP-glucosyl transferase
9615Aminotransferase class-III
224Ribosomal protein S19
112DNA gyrase B
7310Thiamine pyrophosphate enzyme, central domain
538Lyase
224Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
112Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
112Indole-3-glycerol phosphate synthase
112Aromatic amino acid lyase
112Pyruvate kinase, barrel domain
101020Kinesin motor domain
313162DnaJ domain
141428Proteasome subunit
224Major intrinsic protein
112ATP synthase
235Glycosyl hydrolase family 1
1123'5'-cyclic nucleotide phosphodiesterase
112Profilin
224Ribosomal protein L22p/L17e
224Ribosomal protein L14p/L23e
121830Ubiquitin family
459Cofilin/tropomyosin-type actin-binding protein
22414-3-3 protein
5510Alkaline phosphatase
347Zinc carboxypeptidase
212445Aldo/keto reductase family
141327Myb-like DNA-binding domain
448Forkhead domain
112Ribosomal protein L16p/L10e
123Ribosomal protein S14p/S29e
5510FKBP-type peptidyl-prolyl cis-trans isomerase
112Glutathione peroxidase
213
6612Flavodoxin
112Calreticulin family
162844Common central domain of tyrosinase
7815Aminotransferase class-V
112Ribonucleotide reductase, small chain
403878DEAD/DEAH box helicase
7374147Helicase conserved C-terminal domain
213EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
224Ribosomal protein L23
224Pyridoxal-dependent decarboxylase, C-terminal sheet domain
224Ribosomal protein L5
6713Pyridoxal-dependent decarboxylase conserved domain
235Citrate synthase, C-terminal domain
5510GHMP kinases N terminal domain
5510Biotin carboxylase, N-terminal domain
112Tryptophan synthase alpha chain
9918Pyridoxal-phosphate dependent enzyme
161733NUDIX domain
9817pfkB family carbohydrate kinase
71926Glycosyl hydrolases family 28
224Ribosomal protein L3
224Ribosomal protein L11, RNA binding domain
131629Histidine phosphatase superfamily (branch 1)
112Thymidylate synthase
336Lipoxygenase
549ATP synthase alpha/beta chain, C terminal domain
5510Calponin homology (CH) domain
5510Glutamine amidotransferases class-II
224Ribosomal protein S15
112Thaumatin family
112Fructose-1-6-bisphosphatase, N-terminal domain
112Ribonucleotide reductase, all-alpha domain
224Ribosomal protein S2
224SRF-type transcription factor (DNA-binding and dimerisation domain)
8816GATA zinc finger
242650Amino acid permease
448Prolyl oligopeptidase family
224Ribosomal protein L30p/L7e
7815Histidine phosphatase superfamily (branch 2)
112Respiratory-chain NADH dehydrogenase, 30 Kd subunit
459Aconitase family (aconitate hydratase)
459Glycosyl hydrolase family 10
5510Glycosyl hydrolases family 17
224Ribosomal protein S5, N-terminal domain
112Nucleoside diphosphate kinase
213Ribosomal protein S10p/S20e
459Arrestin (or S-antigen), N-terminal domain
112Phosphoglucose isomerase
112Carbohydrate phosphorylase
112SecY translocase
112Respiratory-chain NADH dehydrogenase, 49 Kd subunit
224Ribosomal protein L6
7815Polyprenyl synthetase
336Hexokinase
8816Dynamin family
112Transcription factor TFIID (or TATA-binding protein, TBP)
459Rieske [2Fe-2S] domain
7714Biotin-requiring enzyme
112Phosphofructokinase
224Ribosomal protein S17
112Hydroxymethylglutaryl-coenzyme A reductase
336FGGY family of carbohydrate kinases, N-terminal domain
91019Enoyl-CoA hydratase/isomerase
224Ribosomal protein S9/S16
224Transcription factor TFIIB repeat
7714Cytidine and deoxycytidylate deaminase zinc-binding region
112Molybdopterin oxidoreductase
10616Chromo (CHRromatin Organisation MOdifier) domain
224Phosphatidylinositol-specific phospholipase C, Y domain
336Phosphatidylinositol-specific phospholipase C, X domain
459D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
336Malic enzyme, N-terminal domain
112PEP-utilising enzyme, mobile domain
1126-phosphogluconate dehydrogenase, C-terminal domain
459Multicopper oxidase
9918WW domain
224Ribosomal RNA adenine dimethylase
131120251WD domain, G-beta repeat
459Heavy-metal-associated domain
448Adenylate kinase
224Phosphoglucomutase/phosphomannomutase, C-terminal domain
224Ribosomal protein S8
224Ribosomal protein S11
336LIM domain
6814Matrixin
325Regulator of chromosome condensation (RCC1) repeat
224Ribosomal protein S13/S18
224chorismate binding enzyme
33660s Acidic ribosomal protein
448Prenyltransferase and squalene oxidase repeat
5510Protein kinase C terminal domain
112Single-strand binding protein family
112S-adenosylmethionine synthetase, N-terminal domain
7714Bromodomain
7916Acyl-CoA dehydrogenase, C-terminal domain
151732Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
224Ribonuclease T2 family
336HSF-type DNA-binding
224SRP54-type protein, GTPase domain
112Urease alpha-subunit, N-terminal domain
41317Serine carboxypeptidase
8816Phosphatidylinositol 3- and 4-kinase
112Transketolase, thiamine diphosphate binding domain
358Glycosyl hydrolases family 11
347Inositol monophosphatase family
448Glutaredoxin
224Isocitrate lyase family
224Serine hydroxymethyltransferase
224Iron-containing alcohol dehydrogenase
213Ribosomal protein L10
538KOW motif
112Ribosomal protein L34
213RF-1 domain
235Sodium:solute symporter family
112Imidazoleglycerol-phosphate dehydratase
112DNA polymerase family A
112IMP dehydrogenase / GMP reductase domain
112Glucose-6-phosphate dehydrogenase, NAD binding domain
6612Protein phosphatase 2C
336Nucleotidyl transferase
224Carbonic anhydrase
224Phosphoribulokinase / Uridine kinase family
5510Fatty acid desaturase
6612MutS domain V
112Delta-aminolevulinic acid dehydratase
235Arginase family
6612MCM P-loop domain
224Squalene/phytoene synthase
8816FHA domain
222345AMP-binding enzyme
336G-protein alpha subunit
91019HMG (high mobility group) box
171633His Kinase A (phospho-acceptor) domain
224Armadillo/beta-catenin-like repeat
363167Tetratricopeptide repeat
336Ion transport protein
112DNA gyrase/topoisomerase IV, subunit A
101222BRCA1 C Terminus (BRCT) domain
6612Glycosyl transferases group 1
437Glycosyl transferase family 2
314SAM domain (Sterile alpha motif)
112linker histone H1 and H5 family
112Ribosomal protein L7/L12 C-terminal domain
7916Pectate lyase
112ribonuclease
112Urease, gamma subunit
336CoA-ligase
7815Phosphopantetheine attachment site
235Formyl transferase
9918Metallopeptidase family M24
141024Leucine Rich Repeat
252651alpha/beta hydrolase fold
336RNA polymerase Rpb2, domain 6
6511PB1 domain
224Staphylococcal nuclease homologue
101020Rab-GTPase-TBC domain
112Tudor domain
123WH1 domain
6612Zinc finger, ZZ type
213HRDC domain
101020CBS domain
224Ribosomal protein L13
224Ribosomal protein L4/L1 family
112Clp protease
448S1 RNA binding domain
112HIUase/Transthyretin family
5510AhpC/TSA family
6410tRNA synthetases class I (W and Y)
224UvrD/REP helicase N-terminal domain
549Rhodanese-like domain
224Universal stress protein family
292756Acetyltransferase (GNAT) family
112SecE/Sec61-gamma subunits of protein translocation complex
112C-terminal regulatory domain of Threonine dehydratase
224AIR synthase related protein, N-terminal domain
8816tRNA synthetase class II core domain (G, H, P, S and T)
224SpoU rRNA Methylase family
325Tetrapyrrole (Corrin/Porphyrin) Methylases
112Glycosyl transferase family, a/b domain
112PDZ domain
224Class II Aldolase and Adducin N-terminal domain
448Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
549Fes/CIP4, and EFC/F-BAR homology domain
549IQ calmodulin-binding motif
224Phosphoinositide 3-kinase family, accessory domain (PIK domain)
7714Phospholipase D Active site motif
112Regulator of G protein signaling domain
448GTPase-activator protein for Ras-like GTPase
5510RasGEF domain
6612RasGEF N-terminal motif
9918RhoGAP domain
6612RhoGEF domain
111526SPRY domain
336RNA polymerase Rpb1, domain 2
123Guanylate kinase
358Gelsolin repeat
101121UBA/TS-N domain
151631PHD-finger
11GGL domain
6612HECT-domain (ubiquitin-transferase)
112Helix-hairpin-helix motif
112MSP (Major sperm protein) domain
6612Ribonuclease III domain
224Region in Clathrin and VPS
325RanBP1 domain
224PPIC-type PPIASE domain
224Zn-finger in Ran binding protein and others
141327Zinc finger C-x8-C-x5-C-x3-H type (and similar)
325Poly(ADP-ribose) polymerase catalytic domain
112Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
270233503F-box domain
112Elongation factor 1 gamma, conserved domain
224Calpain family cysteine protease
224Copper fist DNA binding domain
7815CRAL/TRIO domain
342660BTB/POZ domain
8715Ricin-type beta-trefoil lectin domain
112Inhibitor of Apoptosis domain
347Voltage gated chloride channel
8412Caspase domain
7916GDSL-like Lipase/Acylhydrolase
112Poly-adenylate binding protein, unique domain
112POLO box duplicated region
151429ABC transporter transmembrane region
213Integrase core domain
5510FAD binding domain
145Condensation domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
112HAMP domain
224ribosomal L5P family C-terminus
6612Insulinase (Peptidase family M16)
336Dehydrogenase E1 component
112Lumazine binding domain
7714Elongation factor G C-terminus
549HMGL-like
448DnaJ central domain
11Starch binding domain
224Ribosomal protein L1p/L10e family
8816Cation transporting ATPase, C-terminus
9918Cation transporter/ATPase, N-terminus
112dUTPase
448Aconitase C-terminal domain
336Amino acid kinase family
112N-(5'phosphoribosyl)anthranilate (PRA) isomerase
5712Acyl transferase domain
112Urease beta subunit
459Dihydrodipicolinate synthetase family
282856haloacid dehalogenase-like hydrolase
134Glycosyl hydrolases family 2
15823Glycosyl hydrolases family 18
112Proliferating cell nuclear antigen, N-terminal domain
112Acylphosphatase
112Adenylosuccinate synthetase
112Asparaginase, N-terminal
336Peptidase S24-like
112Inorganic pyrophosphatase
141428Glycosyl hydrolases family 16
448Glycosyl hydrolases family 15
112NADH:flavin oxidoreductase / NADH oxidase family
1123-hydroxyacyl-CoA dehydrogenase, C-terminal domain
112Glycosyl hydrolase family 20, catalytic domain
336HhH-GPD superfamily base excision DNA repair protein
112AIR carboxylase
91019GMC oxidoreductase
224Asparagine synthase
76100176Fungal cellulose binding domain
6612Septin
112EF-1 guanine nucleotide exchange domain
112Homoserine dehydrogenase
134Flavin-binding monooxygenase-like
336tRNA synthetases class I (E and Q), catalytic domain
112tRNA synthetases class I (R)
448XPG N-terminal domain
459Metallo-beta-lactamase superfamily
112F5/8 type C domain
224Choline/Carnitine o-acyltransferase
112Putative esterase
112Ferrochelatase
224Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
336RNB domain
224Dioxygenase
235CNH domain
224Diacylglycerol kinase catalytic domain
81321Dual specificity phosphatase, catalytic domain
448P21-Rho-binding domain
121224PX domain
347Ras association (RalGDS/AF-6) domain
5510UBX domain
347VHS domain
112Phosphoinositide 3-kinase C2
224DAHP synthetase I family
549Carbon-nitrogen hydrolase
112N-acetyltransferase
112Prephenate dehydratase
347Syntaxin
5510Pumilio-family RNA binding repeat
6612Histone-like transcription factor (CBF/NF-Y) and archaeal histone
112Pterin binding enzyme
213ER lumen protein retaining receptor
213Glycoprotease family
112Histidinol dehydrogenase
448impB/mucB/samB family
112
112Ribosomal L15
112Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal L28 family
112Ribosomal L29 protein
11Ribosomal L39 protein
112Ribosomal S17
112Ribulose-phosphate 3 epimerase family
112Translationally controlled tumour protein
6511Glycosyl hydrolase family 7
112RNA pseudouridylate synthase
448Histone deacetylase domain
336POT family
112PWWP domain
131225SET domain
5510Isochorismatase family
224Permease family
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
459XPG I-region
11Acetokinase family
224DNA photolyase
112Nitroreductase family
112Sulfatase
1126,7-dimethyl-8-ribityllumazine synthase
112Ribosomal protein S16
325Acyl CoA binding protein
448Cullin family
5611FAD binding domain
4610O-methyltransferase domain
549EamA-like transporter family
224
8816ThiF family
112Ribosomal family S4e
7916Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
336Ammonium Transporter Family
347Sulfate permease family
112MATH domain
224Dehydratase family
112Transaldolase/Fructose-6-phosphate aldolase
123Mechanosensitive ion channel
112GTP cyclohydrolase II
1123,4-dihydroxy-2-butanone 4-phosphate synthase
448Adaptor complexes medium subunit family
7714Exonuclease
224Dipeptidyl peptidase IV (DPP IV) N-terminal region
11NB-ARC domain
91120Glycosyl hydrolase family 3 N terminal domain
112Ribosomal protein L44
112DNA-dependent RNA polymerase
112FAD binding domain in molybdopterin dehydrogenase
112Glycosyl transferase family 4
224HCO3- transporter family
224Nucleosome assembly protein (NAP)
448Synaptobrevin
112GMP synthase C terminal domain
336Adenosine/AMP deaminase
6612Oxidoreductase FAD-binding domain
11Thioesterase domain
224Histidine biosynthesis protein
336Glycosyltransferase family 20
112UDP-glucose/GDP-mannose dehydrogenase family, central domain
224Carbamoyl-phosphate synthase small chain, CPSase domain
213PAS fold
224Probable molybdopterin binding domain
448Sec1 family
224GDP dissociation inhibitor
6410Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
5510Initiation factor 2 subunit family
224Electron transfer flavoprotein domain
112Uricase
112Ribosomal S3Ae family
112Ribosomal L27 protein
112GTP1/OBG
336Gamma-glutamyltranspeptidase
112Ribosomal L40e family
112GrpE
224TatD related DNase
112Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
459Dynamin central region
2246-O-methylguanine DNA methyltransferase, DNA binding domain
112Bacteriorhodopsin-like protein
224Carboxyl transferase domain
325UbiA prenyltransferase family
224Endoribonuclease L-PSP
314Phosphorylase superfamily
11Cadherin cytoplasmic region
5510Cys/Met metabolism PLP-dependent enzyme
358Glycosyl hydrolases family 31
112NADH ubiquinone oxidoreductase, 20 Kd subunit
6814ABC-2 type transporter
336Amino-transferase class IV
5510CDP-alcohol phosphatidyltransferase
5510ATP dependent DNA ligase domain
448FMN-dependent dehydrogenase
112Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
113-beta hydroxysteroid dehydrogenase/isomerase family
112Glycosyl hydrolases family 38 N-terminal domain
224Nitrite and sulphite reductase 4Fe-4S domain
41014Cutinase
112Ribosomal protein S18
112Clathrin light chain
112Galactose-1-phosphate uridyl transferase, N-terminal domain
426Ubiquitin carboxyl-terminal hydrolase, family 1
112Ribosomal protein S19e
112Ribosomal protein S6e
5712Pectinesterase
336Transcription factor S-II (TFIIS)
112Surface antigen
448emp24/gp25L/p24 family/GOLD
112NifU-like domain
112Cyclin-dependent kinase regulatory subunit
224Asparaginase
112F-actin capping protein, beta subunit
224Fructose-bisphosphate aldolase class-II
224Semialdehyde dehydrogenase, NAD binding domain
325DNA mismatch repair protein, C-terminal domain
112Dephospho-CoA kinase
112MAPEG family
112G10 protein
112Heme oxygenase
112Succinate dehydrogenase/Fumarate reductase transmembrane subunit
112DNA topoisomerase
112Glucose inhibited division protein A
112Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
224RNA 3'-terminal phosphate cyclase
55103' exoribonuclease family, domain 1
112tRNA pseudouridine synthase D (TruD)
112Coenzyme A transferase
448SPFH domain / Band 7 family
325Cytidylyltransferase family
112Formamidopyrimidine-DNA glycosylase N-terminal domain
224GDA1/CD39 (nucleoside phosphatase) family
224GNS1/SUR4 family
112Hydroxymethylglutaryl-coenzyme A synthase N terminal
224Inosine-uridine preferring nucleoside hydrolase
112Ribosomal protein L21e
112Ribosomal protein L36e
112Ribosomal protein L6e
336Phosphatidylethanolamine-binding protein
112
224RIO1 family
213Alanine racemase, N-terminal domain
112Uncharacterized protein family UPF0016
224Putative RNA methylase family UPF0020
224PP-loop family
112Shwachman-Bodian-Diamond syndrome (SBDS) protein
112SNO glutamine amidotransferase family
112Translation initiation factor 1A / IF-1
112Asp/Glu/Hydantoin racemase
336Copper amine oxidase, enzyme domain
224Dihydroorotate dehydrogenase
112Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
112GPR1/FUN34/yaaH family
11Fungal hydrophobin
336
33616S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
448RNA polymerase Rpb3/Rpb11 dimerisation domain
11RNA polymerases N / 8 kDa subunit
112Peptidyl-tRNA hydrolase
112Ribosomal protein L17
112Ribosomal protein L31e
112Ribosomal protein L34e
112Ribosomal protein S28e
224Ribosomal protein S8e
325Shikimate kinase
112Trehalase
224Uncharacterized protein family UPF0029
336Dihydrouridine synthase (Dus)
112Uroporphyrinogen decarboxylase (URO-D)
112ubiE/COQ5 methyltransferase family
112NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
112Beta-eliminating lyase
112Adenylate cyclase associated (CAP) N terminal
224Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
549Clathrin adaptor complex small chain
112Coproporphyrinogen III oxidase
112Dynein light chain type 1
437Ergosterol biosynthesis ERG4/ERG24 family
112DNA/RNA non-specific endonuclease
11Mur ligase family, catalytic domain
112GTP cyclohydrolase I
448HIT domain
224Indoleamine 2,3-dioxygenase
112Mannitol dehydrogenase Rossmann domain
112Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
6612Oxysterol-binding protein
123Phosphomannose isomerase type I
325Protein prenyltransferase alpha subunit repeat
448Pyridoxamine 5'-phosphate oxidase
112Membrane dipeptidase (Peptidase family M19)
112Ribosomal protein L19
224Ribosomal protein L24e
112Ribosomal protein L35Ae
5510Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
112Ribosomal protein S21e
112Ribosomal protein S7e
336Translation initiation factor SUI1
325Putative undecaprenyl diphosphate synthase
112Carbohydrate kinase
112Thioredoxin-like [2Fe-2S] ferredoxin
112SAICAR synthetase
224Xylose isomerase-like TIM barrel
224Alanine dehydrogenase/PNT, C-terminal domain
235Aldose 1-epimerase
112Chorismate synthase
224Cytochrome c/c1 heme lyase
192241FAD dependent oxidoreductase
112F-actin capping protein alpha subunit
112Formate--tetrahydrofolate ligase
112Fibrillarin
112Malate synthase
112Ribosomal protein L19e
112Ribosomal protein S24e
112Ribosomal protein S26e
112TEA/ATTS domain
11XPA protein N-terminal
112Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1127,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
112Phosphoenolpyruvate carboxykinase
112Ribosomal protein L13e
112Telomere recombination
246Glycosyl hydrolases family 35
448CAP-Gly domain
112
112Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
112Creatinase/Prolidase N-terminal domain
123DSBA-like thioredoxin domain
112Pyruvate phosphate dikinase, PEP/pyruvate binding domain
246Peroxidase, family 2
112mRNA capping enzyme, catalytic domain
111021OB-fold nucleic acid binding domain
224Glycosyl hydrolases family 6
7613Kelch motif
112Ribonuclease HII
5510FYVE zinc finger
11DHH family
448Sec7 domain
141731NAD dependent epimerase/dehydratase family
22Heat-labile enterotoxin alpha chain
112Porphobilinogen deaminase, dipyromethane cofactor binding domain
224SIS domain
112Helix-turn-helix
224Phosphate transporter family
336ARID/BRIGHT DNA binding domain
112Chromo shadow domain
112Clathrin propeller repeat
8816JAB1/Mov34/MPN/PAD-1 ubiquitin protease
141529PCI domain
22Astacin (Peptidase family M12A)
112tRNA synthetases class I (C) catalytic domain
8816Oxidoreductase family, NAD-binding Rossmann fold
224tRNA synthetases class II core domain (F)
112tRNA synthetases class II (A)
5510Putative GTPase activating protein for Arf
224tRNA pseudouridine synthase
224ENTH domain
11Jacalin-like lectin domain
112Reprolysin (M12B) family zinc metalloprotease
325NF-X1 type zinc finger
161531LSM domain
336R3H domain
101222Amidase
336BAH domain
213AN1-like Zinc finger
11Peptidase family M13
235Peptidase family M3
336Peptidase family M1 domain
224Peptidase family M41
224Peptidase family M48
22Thermolysin metallopeptidase, catalytic domain
112Acetohydroxy acid isomeroreductase, catalytic domain
112Low molecular weight phosphotyrosine protein phosphatase
112D-mannose binding lectin
112MAGE family
11Mucin-like glycoprotein
224Eukaryotic porin
112GRIP domain
112Skp1 family, dimerisation domain
5510Cytidylyltransferase-like
11Pentapeptide repeats (8 copies)
336PUA domain
112Class-II DAHP synthetase family
111223LysM domain
448S4 domain
112PWI domain
112Proprotein convertase P-domain
549IBR domain, a half RING-finger domain
224Type I 3-dehydroquinase
112Shikimate / quinate 5-dehydrogenase
5510Transmembrane amino acid transporter protein
112Frataxin-like domain
112GXGXG motif
8816FAD binding domain
112V-type ATPase 116kDa subunit family
44Transposase
336Glycosyl transferase family 8
112Phosphoribosyl-AMP cyclohydrolase
112Phosphoribosyl-ATP pyrophosphohydrolase
336Phosphatidylinositol-4-phosphate 5-Kinase
224Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
112Respiratory-chain NADH dehydrogenase 51 Kd subunit
336ATP-NAD kinase
224Iron-sulphur cluster biosynthesis
22Polysaccharide deacetylase
6612DHHC palmitoyltransferase
5510Glycosyl hydrolase family 47
8816PPR repeat
112Adenosylmethionine decarboxylase
22Herpesvirus glycoprotein D/GG/GX domain
8715CorA-like Mg2+ transporter protein
7714Cation efflux family
549Peptidase family M20/M25/M40
5510Acyltransferase
235MatE
6612DnaJ C terminal domain
437Fumarylacetoacetate (FAA) hydrolase family
112Pyruvate ferredoxin/flavodoxin oxidoreductase
112Spermine/spermidine synthase domain
262551FAD binding domain
224Natural resistance-associated macrophage protein
6713PAP2 superfamily
224Aminomethyltransferase folate-binding domain
448MaoC like domain
224Adenylylsulphate kinase
7815G-patch domain
112Putative tRNA binding domain
336GAF domain
3366-phosphofructo-2-kinase
112NifU-like N terminal domain
459Flavin containing amine oxidoreductase
224Cyclin M transmembrane N-terminal domain
415O-methyltransferase
112Glycine cleavage H-protein
448
112Ribosomal protein S27a
8816Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
112I/LWEQ domain
11Transposase DDE domain
5383'-5' exonuclease
11Flavin reductase like domain
112Proline dehydrogenase
347MutS domain I
112Peptide methionine sulfoxide reductase
112Hpt domain
538Choline/ethanolamine kinase
112ATP phosphoribosyltransferase
639Phosphotransferase enzyme family
224SelR domain
336Chitin synthase
112Conserved region in glutamate synthase
2244'-phosphopantetheinyl transferase superfamily
112Peptidase C13 family
336Eukaryotic initiation factor 4E
112Ribosomal protein L32
11CobQ/CobB/MinD/ParA nucleotide binding domain
112Myo-inositol-1-phosphate synthase
224Macro domain
235Type I phosphodiesterase / nucleotide pyrophosphatase
112Ribosomal protein S27
112Glycosyl hydrolase family 12
112Metalloenzyme superfamily
336Proteolipid membrane potential modulator
112SOR/SNZ family
112Riboflavin kinase
347Rhomboid family
91120Sodium/calcium exchanger protein
224Queuine tRNA-ribosyltransferase
224UTP--glucose-1-phosphate uridylyltransferase
112Transcriptional regulator
336Smr domain
112IPP transferase
224Cobalamin-independent synthase, Catalytic domain
325BolA-like protein
112Ham1 family
11LexA DNA binding domain
336FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
11Arylesterase
112Nucleoside transporter
15924Patatin-like phospholipase
336Lysophospholipase catalytic domain
6814Dienelactone hydrolase family
336STAS domain
112Large-conductance mechanosensitive channel, MscL
112Poly A polymerase head domain
112tRNA (Guanine-1)-methyltransferase
112ATP-sulfurylase
112Importin beta binding domain
112Toprim domain
10616MYND finger
347Acyltransferase family
325Sodium Bile acid symporter family
1123-dehydroquinate synthase
314Lipase (class 3)
112Ribosome recycling factor
112Na+ dependent nucleoside transporter N-terminus
112UreD urease accessory protein
112Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
112Ribosomal L22e protein family
112Ribosomal L27e protein family
112Ribosomal L28e protein family
11Ribosomal L29e protein family
112Ribosomal L37ae protein family
112Ribosomal L38e protein family
11Ribosomal L32p protein family
112NIF3 (NGG1p interacting factor 3)
112Alternative oxidase
224DeoC/LacD family aldolase
5510Glycolipid 2-alpha-mannosyltransferase
131326Ferric reductase like transmembrane component
336snoRNA binding domain, fibrillarin
112[2Fe-2S] binding domain
112Surp module
112AICARFT/IMPCHase bienzyme
1125-formyltetrahydrofolate cyclo-ligase family
112ATP synthase subunit D
33Hemerythrin HHE cation binding domain
112Chorismate mutase type II
163248WSC domain
123IPT/TIG domain
112FG-GAP repeat
112Transglutaminase-like superfamily
5510ACT domain
224DIL domain
224FF domain
224NAC domain
336Proteasome/cyclosome repeat
325MOZ/SAS family
112Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
224Putative diphthamide synthesis protein
112Domain of unknown function UPF0086
112AMMECR1
112RibD C-terminal domain
224Domain found in IF2B/IF5
112Memo-like protein
112RNase P subunit p30
112EVE domain
112Iron-sulfur cluster assembly protein
112RNA 2'-phosphotransferase, Tpt1 / KptA family
112Uncharacterised protein family UPF0047
112DNA primase small subunit
112Rpp14/Pop5 family
112Diphthamide synthase
11Putative heavy-metal-binding
112Ribosomal protein L37e
5611Nucleotidyltransferase domain
11Thiamine-binding protein
112eIF-6 family
7916Glycosyl hydrolase family 3 C-terminal domain
112Deoxyhypusine synthase
448Prefoldin subunit
112SRP19 protein
12142650S ribosome-binding GTPase
112Ribosomal protein L14
112Uncharacterised protein family UPF0052
112Protein of unknown function DUF89
11TRAM domain
112Integral membrane protein DUF92
11Thi4 family
112ArgJ family
3710DJ-1/PfpI family
336HD domain
112MoaC family
112Hydantoinase/oxoprolinase
224tRNA intron endonuclease, catalytic C-terminal domain
224Survival protein SurE
6612Amidohydrolase family
112Peptidyl-tRNA hydrolase PTH2
112Double-stranded DNA-binding domain
224Mitochondrial biogenesis AIM24
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
224Translin family
112TFIIE alpha subunit
112N2,N2-dimethylguanosine tRNA methyltransferase
448BNR/Asp-box repeat
448Glycosyl hydrolase family 45
112Carbohydrate binding domain
224eIF4-gamma/eIF5/eIF2-epsilon
112SCP-2 sterol transfer family
347SAP domain
112CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
112Cytochrome c oxidase subunit VIa
112Glycosyl hydrolase family 30 TIM-barrel domain
112MAS20 protein import receptor
257Melibiase
112Aromatic-di-Alanine (AdAR) repeat
112Pheromone A receptor
112SURF4 family
112Palmitoyl protein thioesterase
11260Kd inner membrane protein
112Ornithine decarboxylase antizyme
112SURF1 family
112DAD family
112Hydroxyethylthiazole kinase family
112cAMP phosphodiesterases class-II
112Phosducin
112RHO protein GDP dissociation inhibitor
112Fungal pheromone mating factor STE2 GPCR
224Aminopeptidase I zinc metalloprotease (M18)
5510Permease for cytosine/purines, uracil, thiamine, allantoin
336
336Nuclear transport factor 2 (NTF2) domain
112Adenosine-deaminase (editase) domain
112Beige/BEACH domain
224DENN (AEX-3) domain
224MGS-like domain
112Repair protein Rad1/Rec1/Rad17
112Rap/ran-GAP
6612Sir2 family
325Zn-finger in ubiquitin-hydrolases and other protein
112Kinase associated domain 1
123RNA polymerases M/15 Kd subunit
112Dihydroneopterin aldolase
11Prephenate dehydrogenase
112Glycosyl hydrolase family 26
112XYPPX repeat (two copies)
112Cytochrome C1 family
336PAZ domain
437Piwi domain
112TRAF-type zinc finger
202141AT hook motif
112BAG domain
112Formin Homology 2 Domain
123HAT (Half-A-TPR) repeat
224Hr1 repeat
112Growth-Arrest-Specific Protein 2 Domain
224ATP-dependent protease La (LON) substrate-binding domain
336PXA domain
112Regulatory subunit of type II PKA R-subunit
112STE like transcription factor
224SWIB/MDM2 domain
235Vacuolar sorting protein 9 (VPS9) domain
347WH2 motif
112Putative zinc finger in N-recognin (UBR box)
224Dynamin GTPase effector domain
224GYF domain
224Methylenetetrahydrofolate reductase
112ML domain
112ATP-grasp domain
112Thymidylate kinase
8917PA domain
112Transcriptional Coactivator p15 (PC4)
6612Phospholipase/Carboxylesterase
112NAD(P) transhydrogenase beta subunit
11Biotin protein ligase C terminal domain
11Carboxypeptidase activation peptide
112RFX DNA-binding domain
213FAT domain
336FATC domain
224S1/P1 Nuclease
112Transcription initiation factor IIA, gamma subunit, helical domain
213Transcription initiation factor IID, 18kD subunit
112TFIIF, beta subunit HTH domain
112Ubiquinol-cytochrome C reductase complex 14kD subunit
11Amidinotransferase
224Polysaccharide lyase family 8, super-sandwich domain
112Cytochrome c oxidase subunit Va
112Transcription initiation factor IID, 31kD subunit
336
112Alpha adaptin AP2, C-terminal domain
112Cytochrome oxidase c subunit VIb
11Plastocyanin-like domain
325HORMA domain
112Ubiquinol-cytochrome C reductase hinge protein
112Mitochondrial glycoprotein
112Phytase
336OTU-like cysteine protease
123Glycine cleavage system P-protein
112Mycolic acid cyclopropane synthetase
224Trehalose-phosphatase
224Cell division protein 48 (CDC48), N-terminal domain
1121,3-beta-glucan synthase component
336Dolichyl