PFAM Domains • Geastrales
Annotations/GenomesGeatri1Sphst1TotalAnnotation Description
PFAMs
9,92913,18423,113
227 transmembrane receptor (rhodopsin family)
117 transmembrane receptor (Secretin family)
4768115ATPase family associated with various cellular activities (AAA)
3898136ABC transporter
448ATP synthase alpha/beta family, nucleotide-binding domain
162238Elongation factor Tu GTP binding domain
121224Helix-loop-helix DNA-binding domain
61521Hsp20/alpha crystallin family
91423Hsp70 protein
81119KH domain
11SH2 domain
133144SH3 domain
151429Actin
246993Ankyrin repeat
101020ADP-ribosylation factor family
3768105Eukaryotic aspartyl protease
336Cyclic nucleotide-binding domain
112Cytochrome c
5712Double-stranded RNA binding motif
21719EF hand
114Fe-4S binding domain
11Fibronectin type III domain
105666Glutathione S-transferase, C-terminal domain
224Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
91120Homeodomain
11Laminin EGF domain
22224lactate/malate dehydrogenase, NAD binding domain
4913Myosin head (motor domain)
177506683Cytochrome P450
250229479Protein kinase domain
132134Pyridine nucleotide-disulphide oxidoreductase
394079Ras family
81624Response regulator receiver domain
25732RNase H
6475139RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
112Reverse transcriptase (RNA-dependent DNA polymerase)
33Copper/zinc superoxide dismutase (SODC)
246Iron/manganese superoxide dismutases, alpha-hairpin domain
13619Subtilase family
4358101Sugar (and other) transporter
131730Thioredoxin
448Tubulin/FtsZ family, GTPase domain
77von Willebrand factor type A domain
33129162Zinc finger, C2H2 type
76976Zinc finger, C3HC4 type (RING finger)
52182234Zinc knuckle
325Protein-tyrosine phosphatase
56171227short chain dehydrogenase
3878116Zinc-binding dehydrogenase
51116Thiolase, N-terminal domain
32629Beta-ketoacyl synthase, N-terminal domain
1452Fe-2S iron-sulfur cluster binding domain
112Enolase, C-terminal TIM barrel domain
8816Glutamine amidotransferase class-I
91322TCP-1/cpn60 chaperonin family
3710Glutamine synthetase, catalytic domain
112Triosephosphate isomerase
143246E1-E2 ATPase
162036Core histone H2A/H2B/H3/H4
123Copper binding proteins, plastocyanin/azurin family
71219Alpha amylase, catalytic domain
459Phorbol esters/diacylglycerol binding domain (C1 domain)
4711Bacterial transferase hexapeptide (six repeats)
437tRNA synthetases class I (I, L, M and V)
111324Cyclin, N-terminal domain
3863101Carboxylesterase family
5510DNA polymerase family B
358ATP synthase subunit C
64854Peroxidase
82028Beta-lactamase
459C-5 cytosine-specific DNA methylase
274067Calcineurin-like phosphoesterase
141933Cellulase (glycosyl hydrolase family 5)
6612tRNA synthetases class II (D, K and N)
344377Mitochondrial carrier protein
182947Aminotransferase class I and II
3710Phosphoribosyl transferase domain
151631Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
22Ribosome inactivating protein
213Phosphoglycerate kinase
224Ribosomal protein S4/S9 N-terminal domain
224Ribosomal protein S12/S23
112Chaperonin 10 Kd subunit
153045C2 domain
112132PH domain
9514bZIP transcription factor
184361Aldehyde dehydrogenase family
3884122Fungal Zn(2)-Cys(6) binuclear cluster domain
213455Cytochrome b5-like Heme/Steroid binding domain
72330Oxidoreductase NAD-binding domain
253156SNF2 family N-terminal domain
325Ribosomal protein S7p/S5e
212445Ubiquitin-conjugating enzyme
6612Isocitrate/isopropylmalate dehydrogenase
112Ribosomal Proteins L2, RNA binding domain
325Hsp90 protein
224Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
11Chitin recognition protein
51217Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
268Cupin
325Annexin
3362-oxoacid dehydrogenases acyltransferase (catalytic domain)
224Catalase
224Disintegrin
52126UDP-glucoronosyl and UDP-glucosyl transferase
61117Aminotransferase class-III
224Ribosomal protein S19
112DNA gyrase B
347Thiamine pyrophosphate enzyme, central domain
336Lyase
112Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
112Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
224Indole-3-glycerol phosphate synthase
5813Aromatic amino acid lyase
112Pyruvate kinase, barrel domain
91019Kinesin motor domain
272956DnaJ domain
162137Proteasome subunit
6410Major intrinsic protein
112ATP synthase
246Glycosyl hydrolase family 1
1123'5'-cyclic nucleotide phosphodiesterase
112Profilin
224Ribosomal protein L22p/L17e
224Ribosomal protein L14p/L23e
151732Ubiquitin family
5611Cofilin/tropomyosin-type actin-binding protein
12314-3-3 protein
22Alkaline phosphatase
112Zinc carboxypeptidase
51100151Aldo/keto reductase family
61420Myb-like DNA-binding domain
131528Forkhead domain
11Glycosyl hydrolases family 32 N-terminal domain
314Ribosomal protein L16p/L10e
224Ribosomal protein S14p/S29e
11617FKBP-type peptidyl-prolyl cis-trans isomerase
112Glutathione peroxidase
33
41418Flavodoxin
112Calreticulin family
211334Common central domain of tyrosinase
10717Aminotransferase class-V
112Ribonucleotide reductase, small chain
7067137DEAD/DEAH box helicase
97100197Helicase conserved C-terminal domain
112Fructose-bisphosphate aldolase class-I
12122EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
224Ribosomal protein L23
123Pyridoxal-dependent decarboxylase, C-terminal sheet domain
112Ribosomal protein L5
81119Pyridoxal-dependent decarboxylase conserved domain
437Citrate synthase, C-terminal domain
5510GHMP kinases N terminal domain
61016Biotin carboxylase, N-terminal domain
123Tryptophan synthase alpha chain
81018Pyridoxal-phosphate dependent enzyme
141529NUDIX domain
437pfkB family carbohydrate kinase
71522Glycosyl hydrolases family 28
224Ribosomal protein L3
224Ribosomal protein L11, RNA binding domain
121325Histidine phosphatase superfamily (branch 1)
112Thymidylate synthase
22Lipoxygenase
448ATP synthase alpha/beta chain, C terminal domain
4711Calponin homology (CH) domain
6713Glutamine amidotransferases class-II
235Ribosomal protein S15
11213Thaumatin family
112Fructose-1-6-bisphosphatase, N-terminal domain
123Ribonucleotide reductase, all-alpha domain
224Ribosomal protein S2
224SRF-type transcription factor (DNA-binding and dimerisation domain)
121123GATA zinc finger
83139Amino acid permease
61319Prolyl oligopeptidase family
235Ribosomal protein L30p/L7e
71219Histidine phosphatase superfamily (branch 2)
112Respiratory-chain NADH dehydrogenase, 30 Kd subunit
5611Aconitase family (aconitate hydratase)
51823Glycosyl hydrolase family 10
134Glycosyl hydrolases family 17
224Ribosomal protein S5, N-terminal domain
224Nucleoside diphosphate kinase
213Tetraspanin family
213Ribosomal protein S10p/S20e
6713Arrestin (or S-antigen), N-terminal domain
112Phosphoglucose isomerase
112Carbohydrate phosphorylase
112SecY translocase
112Respiratory-chain NADH dehydrogenase, 49 Kd subunit
224Ribosomal protein L6
4610Polyprenyl synthetase
224Hexokinase
12820Dynamin family
123Transcription factor TFIID (or TATA-binding protein, TBP)
235Rieske [2Fe-2S] domain
11Phytochrome region
81119Biotin-requiring enzyme
112Phosphofructokinase
246Ribosomal protein S17
112Hydroxymethylglutaryl-coenzyme A reductase
448FGGY family of carbohydrate kinases, N-terminal domain
131225Enoyl-CoA hydratase/isomerase
224Ribosomal protein S9/S16
325Transcription factor TFIIB repeat
7916Cytidine and deoxycytidylate deaminase zinc-binding region
123Molybdopterin oxidoreductase
62935Chromo (CHRromatin Organisation MOdifier) domain
437Phosphatidylinositol-specific phospholipase C, Y domain
437Phosphatidylinositol-specific phospholipase C, X domain
7815D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
257Malic enzyme, N-terminal domain
1236-phosphogluconate dehydrogenase, C-terminal domain
202848Multicopper oxidase
71219WW domain
279Ribosomal RNA adenine dimethylase
124370494WD domain, G-beta repeat
358Heavy-metal-associated domain
336Adenylate kinase
213Phosphoglucomutase/phosphomannomutase, C-terminal domain
213Ribosomal protein S8
314Ribosomal protein S11
549LIM domain
527Regulator of chromosome condensation (RCC1) repeat
224Ribosomal protein S13/S18
224chorismate binding enzyme
33660s Acidic ribosomal protein
11ATP synthase B/B' CF(0)
4610Prenyltransferase and squalene oxidase repeat
437Protein kinase C terminal domain
11Single-strand binding protein family
123S-adenosylmethionine synthetase, N-terminal domain
9918Bromodomain
101323Acyl-CoA dehydrogenase, C-terminal domain
161733Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
235Ribonuclease T2 family
459HSF-type DNA-binding
224SRP54-type protein, GTPase domain
123Urease alpha-subunit, N-terminal domain
153853Serine carboxypeptidase
91120Phosphatidylinositol 3- and 4-kinase
123Transketolase, thiamine diphosphate binding domain
44Glycosyl hydrolases family 11
224Inositol monophosphatase family
459Glutaredoxin
336Isocitrate lyase family
112Serine hydroxymethyltransferase
426Iron-containing alcohol dehydrogenase
224Ribosomal protein L10
549KOW motif
112Ribosomal protein L34
11Ribosomal protein L33
347RF-1 domain
112Sodium:solute symporter family
123Imidazoleglycerol-phosphate dehydratase
112DNA polymerase family A
112IMP dehydrogenase / GMP reductase domain
112Glucose-6-phosphate dehydrogenase, NAD binding domain
51116Protein phosphatase 2C
347Nucleotidyl transferase
358Carbonic anhydrase
112Phosphoribulokinase / Uridine kinase family
92433Fatty acid desaturase
51116MutS domain V
112Delta-aminolevulinic acid dehydratase
5510Arginase family
71320MCM P-loop domain
325Squalene/phytoene synthase
111324FHA domain
4372115AMP-binding enzyme
131932G-protein alpha subunit
122739HMG (high mobility group) box
4913His Kinase A (phospho-acceptor) domain
224Armadillo/beta-catenin-like repeat
2297119Tetratricopeptide repeat
347Ion transport protein
112DNA gyrase/topoisomerase IV, subunit A
71118BRCA1 C Terminus (BRCT) domain
8513Glycosyl transferases group 1
336Glycosyl transferase family 2
112SAM domain (Sterile alpha motif)
314linker histone H1 and H5 family
112Ribosomal protein L7/L12 C-terminal domain
112Pectate lyase
11ribonuclease
134Urease, gamma subunit
235CoA-ligase
61521Phosphopantetheine attachment site
224Formyl transferase
121527Metallopeptidase family M24
41721Leucine Rich Repeat
108595alpha/beta hydrolase fold
347RNA polymerase Rpb2, domain 6
6713PB1 domain
235Staphylococcal nuclease homologue
12921Rab-GTPase-TBC domain
112Tudor domain
112WH1 domain
51015Zinc finger, ZZ type
112HRDC domain
61016CBS domain
224Ribosomal protein L13
235Ribosomal protein L4/L1 family
123Clp protease
437S1 RNA binding domain
11HIUase/Transthyretin family
72330AhpC/TSA family
347tRNA synthetases class I (W and Y)
11UvrD/REP helicase N-terminal domain
10414Rhodanese-like domain
235Universal stress protein family
186179Acetyltransferase (GNAT) family
112SecE/Sec61-gamma subunits of protein translocation complex
112C-terminal regulatory domain of Threonine dehydratase
246AIR synthase related protein, N-terminal domain
5712tRNA synthetase class II core domain (G, H, P, S and T)
44Phage integrase family
224Tetrapyrrole (Corrin/Porphyrin) Methylases
112Glycosyl transferase family, a/b domain
31013Class II Aldolase and Adducin N-terminal domain
347Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
358Fes/CIP4, and EFC/F-BAR homology domain
224IQ calmodulin-binding motif
224Phosphoinositide 3-kinase family, accessory domain (PIK domain)
235Phospholipase D Active site motif
22Regulator of G protein signaling domain
5611GTPase-activator protein for Ras-like GTPase
6915RasGEF domain
51217RasGEF N-terminal motif
141125RhoGAP domain
141024RhoGEF domain
437SPRY domain
336RNA polymerase Rpb1, domain 2
112Guanylate kinase
358Gelsolin repeat
61016UBA/TS-N domain
161531PHD-finger
123GGL domain
448HECT-domain (ubiquitin-transferase)
22Helix-hairpin-helix motif
112MSP (Major sperm protein) domain
3912Ribonuclease III domain
516Region in Clathrin and VPS
358RanBP1 domain
123PPIC-type PPIASE domain
336Zn-finger in Ran binding protein and others
92332Zinc finger C-x8-C-x5-C-x3-H type (and similar)
11B-box zinc finger
235Poly(ADP-ribose) polymerase catalytic domain
235Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
13192205F-box domain
123Elongation factor 1 gamma, conserved domain
6410Calpain family cysteine protease
224Copper fist DNA binding domain
71219CRAL/TRIO domain
352964BTB/POZ domain
112334Ricin-type beta-trefoil lectin domain
123Inhibitor of Apoptosis domain
336Voltage gated chloride channel
22729Caspase domain
101727GDSL-like Lipase/Acylhydrolase
213Poly-adenylate binding protein, unique domain
123POLO box duplicated region
184361ABC transporter transmembrane region
99Integrase core domain
41721FAD binding domain
44Condensation domain
415S-adenosyl-L-homocysteine hydrolase, NAD binding domain
145HAMP domain
224ribosomal L5P family C-terminus
5712Insulinase (Peptidase family M16)
448Dehydrogenase E1 component
112Lumazine binding domain
81018Elongation factor G C-terminus
6713HMGL-like
448DnaJ central domain
235Starch binding domain
325Ribosomal protein L1p/L10e family
6814Cation transporting ATPase, C-terminus
61319Cation transporter/ATPase, N-terminus
22dUTPase
5611Aconitase C-terminal domain
426Amino acid kinase family
224N-(5'phosphoribosyl)anthranilate (PRA) isomerase
31518Acyl transferase domain
134Urease beta subunit
347Dihydrodipicolinate synthetase family
105262haloacid dehalogenase-like hydrolase
325Glycosyl hydrolases family 2
101929Glycosyl hydrolases family 18
213Proliferating cell nuclear antigen, N-terminal domain
11Acylphosphatase
123Adenylosuccinate synthetase
123Asparaginase, N-terminal
358Peptidase S24-like
134Inorganic pyrophosphatase
8816Glycosyl hydrolases family 16
235Glycosyl hydrolases family 15
83745NADH:flavin oxidoreductase / NADH oxidase family
1123-hydroxyacyl-CoA dehydrogenase, C-terminal domain
437Glycosyl hydrolase family 20, catalytic domain
459HhH-GPD superfamily base excision DNA repair protein
112AIR carboxylase
42114156GMC oxidoreductase
257Asparagine synthase
185876Fungal cellulose binding domain
8715Septin
112EF-1 guanine nucleotide exchange domain
123Homoserine dehydrogenase
134Flavin-binding monooxygenase-like
246tRNA synthetases class I (E and Q), catalytic domain
123tRNA synthetases class I (R)
4711XPG N-terminal domain
51722Metallo-beta-lactamase superfamily
11F5/8 type C domain
4812Choline/Carnitine o-acyltransferase
112Putative esterase
112Glycosyl hydrolase family 9
112Ferrochelatase
224Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
336RNB domain
369Dioxygenase
6410CNH domain
123Diacylglycerol kinase catalytic domain
161329Dual specificity phosphatase, catalytic domain
112MyTH4 domain
369P21-Rho-binding domain
151227PX domain
246Ras association (RalGDS/AF-6) domain
549UBX domain
549VHS domain
112Phosphoinositide 3-kinase C2
3912DAHP synthetase I family
5510Carbon-nitrogen hydrolase
145N-acetyltransferase
112Prephenate dehydratase
4610Syntaxin
4610Pumilio-family RNA binding repeat
9716Histone-like transcription factor (CBF/NF-Y) and archaeal histone
112Pterin binding enzyme
134ER lumen protein retaining receptor
224tRNA N6-adenosine threonylcarbamoyltransferase
112Histidinol dehydrogenase
358impB/mucB/samB family
11
112Ribosomal L15
33Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal prokaryotic L21 protein
112Ribosomal L28 family
112Ribosomal L29 protein
11Ribosomal L39 protein
112Ribosomal S17
112Ribulose-phosphate 3 epimerase family
112Translationally controlled tumour protein
31114Glycosyl hydrolase family 7
224RNA pseudouridylate synthase
81119Histone deacetylase domain
235POT family
224PWWP domain
271239SET domain
61016Isochorismatase family
178Permease family
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
61016XPG I-region
235Acetokinase family
11Cation-independent mannose-6-phosphate receptor repeat
112Cytosol aminopeptidase family, catalytic domain
1126,7-dimethyl-8-ribityllumazine synthase
11Ribosomal protein S16
336Acyl CoA binding protein
5611Cullin family
112Elongation factor TS
358FAD binding domain
71724O-methyltransferase domain
4610EamA-like transporter family
33
81321ThiF family
112Ribosomal family S4e
134Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
235Ammonium Transporter Family
549Sulfate permease family
112MATH domain
336Dehydratase family
134Transaldolase/Fructose-6-phosphate aldolase
347Mechanosensitive ion channel
213GTP cyclohydrolase II
1123,4-dihydroxy-2-butanone 4-phosphate synthase
4711Adaptor complexes medium subunit family
6814Exonuclease
112Dipeptidyl peptidase IV (DPP IV) N-terminal region
26935NB-ARC domain
92231Glycosyl hydrolase family 3 N terminal domain
112Ribosomal protein L44
11Sodium:sulfate symporter transmembrane region
112DNA-dependent RNA polymerase
112Glycosyl transferase family 4
112HCO3- transporter family
279Nucleosome assembly protein (NAP)
5611Synaptobrevin
112GMP synthase C terminal domain
426Phage lysozyme
11LAGLIDADG endonuclease
4913Adenosine/AMP deaminase
336Oxidoreductase FAD-binding domain
189Thioesterase domain
235Histidine biosynthesis protein
369Glycosyltransferase family 20
11UDP-glucose/GDP-mannose dehydrogenase family, central domain
224Carbamoyl-phosphate synthase small chain, CPSase domain
112Probable molybdopterin binding domain
448Sec1 family
224GDP dissociation inhibitor
6814Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
448Initiation factor 2 subunit family
22PQQ enzyme repeat
224Electron transfer flavoprotein domain
112Uricase
112Ribosomal S3Ae family
11Ribosomal L27 protein
112GTP1/OBG
347Gamma-glutamyltranspeptidase
11Ribosomal L40e family
11GrpE
246TatD related DNase
213Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
11415Dynamin central region
2356-O-methylguanine DNA methyltransferase, DNA binding domain
134Bacteriorhodopsin-like protein
279Carboxyl transferase domain
91524UbiA prenyltransferase family
31114Endoribonuclease L-PSP
314Phosphorylase superfamily
123Mannose-6-phosphate isomerase
65763Cys/Met metabolism PLP-dependent enzyme
91120Glycosyl hydrolases family 31
112NADH ubiquinone oxidoreductase, 20 Kd subunit
71825ABC-2 type transporter
55Bestrophin, RFP-TM, chloride channel
336Amino-transferase class IV
459CDP-alcohol phosphatidyltransferase
11Calpain large subunit, domain III
4610ATP dependent DNA ligase domain
448FMN-dependent dehydrogenase
123Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
3253-beta hydroxysteroid dehydrogenase/isomerase family
112Glycosyl hydrolases family 38 N-terminal domain
123Nitrite and sulphite reductase 4Fe-4S domain
32831Cutinase
11Ribosomal protein S18
11Clathrin light chain
112Galactose-1-phosphate uridyl transferase, N-terminal domain
347Ubiquitin carboxyl-terminal hydrolase, family 1
123Ribosomal protein S19e
112Ribosomal protein S6e
358Pectinesterase
437Transcription factor S-II (TFIIS)
112Omp85 superfamily domain
459emp24/gp25L/p24 family/GOLD
112NifU-like domain
112Cyclin-dependent kinase regulatory subunit
224Asparaginase
112F-actin capping protein, beta subunit
235Fructose-bisphosphate aldolase class-II
246Semialdehyde dehydrogenase, NAD binding domain
336DNA mismatch repair protein, C-terminal domain
336Alpha-L-fucosidase
112Dephospho-CoA kinase
426MAPEG family
112G10 protein
112Heme oxygenase
112Succinate dehydrogenase/Fumarate reductase transmembrane subunit
112DNA topoisomerase
11Glucose inhibited division protein A
134Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
224RNA 3'-terminal phosphate cyclase
57123' exoribonuclease family, domain 1
112tRNA pseudouridine synthase D (TruD)
112Coenzyme A transferase
448SPFH domain / Band 7 family
246Cytidylyltransferase family
11Formamidopyrimidine-DNA glycosylase N-terminal domain
235GDA1/CD39 (nucleoside phosphatase) family
167GNS1/SUR4 family
123Hydroxymethylglutaryl-coenzyme A synthase N terminal
336Inosine-uridine preferring nucleoside hydrolase
112Ribosomal protein L21e
112Ribosomal protein L36e
112Ribosomal protein L6e
549Phosphatidylethanolamine-binding protein
11
325RIO1 family
11Ribosomal protein S21
22Alanine racemase, N-terminal domain
123Uncharacterized protein family UPF0016
11Putative RNA methylase family UPF0020
224PP-loop family
112Shwachman-Bodian-Diamond syndrome (SBDS) protein
134SNO glutamine amidotransferase family
123Translation initiation factor 1A / IF-1
11Asp/Glu/Hydantoin racemase
145Copper amine oxidase, enzyme domain
134Dihydroorotate dehydrogenase
325Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
11Glycosyl hydrolases family 25
5510GPR1/FUN34/yaaH family
33127160Fungal hydrophobin
145Macrophage migration inhibitory factor (MIF)
134
33616S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
246RNA polymerase Rpb3/Rpb11 dimerisation domain
112RNA polymerases N / 8 kDa subunit
213Peptidyl-tRNA hydrolase
112Ribosomal protein L17
123Ribosomal protein L31e
112Ribosomal protein L34e
123Ribosomal protein S28e
224Ribosomal protein S8e
21113Shikimate kinase
246Trehalase
224Uncharacterized protein family UPF0029
347Dihydrouridine synthase (Dus)
112Uroporphyrinogen decarboxylase (URO-D)
123ubiE/COQ5 methyltransferase family
112NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
112Beta-eliminating lyase
11Adenylate cyclase associated (CAP) N terminal
224Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
7411Clathrin adaptor complex small chain
112Coproporphyrinogen III oxidase
112Dynein light chain type 1
22224Ergosterol biosynthesis ERG4/ERG24 family
112DNA/RNA non-specific endonuclease
112Formate/nitrite transporter
112GTP cyclohydrolase I
3710HIT domain
325Indoleamine 2,3-dioxygenase
145Mannitol dehydrogenase Rossmann domain
112Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
4711Oxysterol-binding protein
123Phosphomannose isomerase type I
336Protein prenyltransferase alpha subunit repeat
224Pyridoxamine 5'-phosphate oxidase
123Membrane dipeptidase (Peptidase family M19)
112Ribosomal protein L19
224Ribosomal protein L24e
112Ribosomal protein L35Ae
5510Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
112Ribosomal protein S21e
11Ribosomal protein S6
112Ribosomal protein S7e
336Translation initiation factor SUI1
112Putative undecaprenyl diphosphate synthase
213Carbohydrate kinase
123Thioredoxin-like [2Fe-2S] ferredoxin
112SAICAR synthetase
257Xylose isomerase-like TIM barrel
213Alanine dehydrogenase/PNT, C-terminal domain
448Aldose 1-epimerase
112Chorismate synthase
437Cytochrome c/c1 heme lyase
83139FAD dependent oxidoreductase
112F-actin capping protein alpha subunit
112Formate--tetrahydrofolate ligase
112Fibrillarin
112Malate synthase
112Ribosomal protein L19e
11Ribosomal protein L9, N-terminal domain
11Ribosomal protein S24e
112Ribosomal protein S26e
11Membrane-associating domain
11TEA/ATTS domain
112Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1127,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
123Phosphoenolpyruvate carboxykinase
112Ribosomal protein L13e
112Telomere recombination
41115Glycosyl hydrolases family 35
448CAP-Gly domain
11
336Creatinase/Prolidase N-terminal domain
213DSBA-like thioredoxin domain
146074Peroxidase, family 2
123mRNA capping enzyme, catalytic domain
7916OB-fold nucleic acid binding domain
145Glycosyl hydrolases family 6
11011Kelch motif
112Ribonuclease HII
7714FYVE zinc finger
213DHH family
5510Sec7 domain
134558NAD dependent epimerase/dehydratase family
123Porphobilinogen deaminase, dipyromethane cofactor binding domain
11516SIS domain
134Helix-turn-helix
246ARID/BRIGHT DNA binding domain
11Collagen triple helix repeat (20 copies)
11Chromo shadow domain
11Clathrin propeller repeat
71017JAB1/Mov34/MPN/PAD-1 ubiquitin protease
151732PCI domain
134tRNA synthetases class I (C) catalytic domain
151429Oxidoreductase family, NAD-binding Rossmann fold
235tRNA synthetases class II core domain (F)
213tRNA synthetases class II (A)
448Putative GTPase activating protein for Arf
224tRNA pseudouridine synthase
224ENTH domain
22Reprolysin (M12B) family zinc metalloprotease
11NF-X1 type zinc finger
131528LSM domain
325R3H domain
81422Amidase
6713BAH domain
314AN1-like Zinc finger
123Peptidase family M13
235Peptidase family M3
21214Peptidase family M1 domain
235Peptidase family M41
336Peptidase family M48
213Acetohydroxy acid isomeroreductase, catalytic domain
112Low molecular weight phosphotyrosine protein phosphatase
112MAGE family
224Eukaryotic porin
224Transglycosylase SLT domain
123GRIP domain
11Skp1 family, dimerisation domain
5611Cytidylyltransferase-like
246PUA domain
112Class-II DAHP synthetase family
61319LysM domain
33PLAT/LH2 domain
358S4 domain
325PWI domain
123Proprotein convertase P-domain
61016IBR domain, a half RING-finger domain
11011Type I 3-dehydroquinase
279Shikimate / quinate 5-dehydrogenase
91120Transmembrane amino acid transporter protein
112Frataxin-like domain
213GXGXG motif
165672FAD binding domain
112V-type ATPase 116kDa subunit family
22Transposase
358Glycosyl transferase family 8
112Phosphoribosyl-AMP cyclohydrolase
112Phosphoribosyl-ATP pyrophosphohydrolase
347Phosphatidylinositol-4-phosphate 5-Kinase
224Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
112Respiratory-chain NADH dehydrogenase 51 Kd subunit
224ATP-NAD kinase
123Iron-sulphur cluster biosynthesis
71320Polysaccharide deacetylase
6915DHHC palmitoyltransferase
81119Glycosyl hydrolase family 47
51318PPR repeat
112Adenosylmethionine decarboxylase
123GIY-YIG catalytic domain
7512CorA-like Mg2+ transporter protein
61420Cation efflux family
81523Peptidase family M20/M25/M40
6511Acyltransferase
268MatE
6511DnaJ C terminal domain
448Fumarylacetoacetate (FAA) hydrolase family
11Reprolysin family propeptide
235Spermine/spermidine synthase domain
287199FAD binding domain
112Natural resistance-associated macrophage protein
8715PAP2 superfamily
224Aminomethyltransferase folate-binding domain
3710MaoC like domain
22Myosin tail
224Adenylylsulphate kinase
9918G-patch domain
112Putative tRNA binding domain
123GAF domain
2246-phosphofructo-2-kinase
112NifU-like N terminal domain
42125Flavin containing amine oxidoreductase
325Cyclin M transmembrane N-terminal domain
336O-methyltransferase
112Glycine cleavage H-protein
33
112Ribosomal protein S27a
101121Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
112I/LWEQ domain
1515Transposase DDE domain
11Transposase
4483'-5' exonuclease
22Flavin reductase like domain
112Proline dehydrogenase
6713MutS domain I
112Peptide methionine sulfoxide reductase
112Hpt domain
213Ribosomal protein L35
112Choline/ethanolamine kinase
112ATP phosphoribosyltransferase
331245Phosphotransferase enzyme family
11ATPase domain predominantly from Archaea
112SelR domain
448Chitin synthase
112Conserved region in glutamate synthase
2354'-phosphopantetheinyl transferase superfamily
112Peptidase C13 family
325Eukaryotic initiation factor 4E
112Ribosomal protein L32
123Myo-inositol-1-phosphate synthase
213Macro domain
347Type I phosphodiesterase / nucleotide pyrophosphatase
112Ribosomal protein S27
257Glycosyl hydrolase family 12
134Metalloenzyme superfamily
639Proteolipid membrane potential modulator
11SOR/SNZ family
112Riboflavin kinase
11Caulimovirus viroplasmin
235Rhomboid family
6713Sodium/calcium exchanger protein
213Queuine tRNA-ribosyltransferase
224UTP--glucose-1-phosphate uridylyltransferase
112Transcriptional regulator
235Smr domain
112IPP transferase
235Cobalamin-independent synthase, Catalytic domain
347BolA-like protein
224Ham1 family
11LexA DNA binding domain
224FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
11UreF
22Arylesterase
213Nucleoside transporter
365692Patatin-like phospholipase
2911Lysophospholipase catalytic domain
81018Dienelactone hydrolase family
336STAS domain
55Large-conductance mechanosensitive channel, MscL
112Poly A polymerase head domain
224tRNA (Guanine-1)-methyltransferase
112ATP-sulfurylase
112Importin beta binding domain
213Toprim domain
134255MYND finger
112Acyl-CoA oxidase
123Sodium Bile acid symporter family
1673-dehydroquinate synthase
11Galactosyltransferase
112132Lipase (class 3)
112Ribosome recycling factor
112Divalent cation transporter
314Na+ dependent nucleoside transporter N-terminus
213UreD urease accessory protein
112Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
112Ribosomal L22e protein family
112Ribosomal L27e protein family
213Ribosomal L28e protein family
11Ribosomal L29e protein family
112Ribosomal L37ae protein family
112Ribosomal L38e protein family
112Ribosomal L32p protein family
112NIF3 (NGG1p interacting factor 3)
112Alternative oxidase
51419Glycolipid 2-alpha-mannosyltransferase
7815Ferric reductase like transmembrane component
336snoRNA binding domain, fibrillarin
22LIM-domain binding protein
224Surp module
112AICARFT/IMPCHase bienzyme
1345-formyltetrahydrofolate cyclo-ligase family
123ATP synthase subunit D
213Hemerythrin HHE cation binding domain
112Chorismate mutase type II
81422WSC domain
112IPT/TIG domain
213Transglutaminase-like superfamily
123ACT domain
224DIL domain
11HNH endonuclease
224FF domain
224NAC domain
224Proteasome/cyclosome repeat
112START domain
336MOZ/SAS family
235Putative diphthamide synthesis protein
112Domain of unknown function UPF0086
235BadF/BadG/BcrA/BcrD ATPase family
112AMMECR1
112RibD C-terminal domain
224Domain found in IF2B/IF5
112Memo-like protein
112RNase P subunit p30
112EVE domain
123Iron-sulfur cluster assembly protein
112RNA 2'-phosphotransferase, Tpt1 / KptA family
112Uncharacterised protein family UPF0047
112DNA primase small subunit
123Rpp14/Pop5 family
112Diphthamide synthase
112Ribosomal protein L37e
347Nucleotidyltransferase domain
123Thiamine-binding protein
112eIF-6 family
91928Glycosyl hydrolase family 3 C-terminal domain
112Deoxyhypusine synthase
11Alba
358Prefoldin subunit
112SRP19 protein
16122850S ribosome-binding GTPase
112Ribosomal protein L14
112Uncharacterised protein family UPF0052
336Protein of unknown function DUF89
112Integral membrane protein DUF92
123Thi4 family
11Integral membrane protein EMC3/TMCO1-like
112ArgJ family
31720DJ-1/PfpI family
4610HD domain
347Hydantoinase/oxoprolinase
213tRNA intron endonuclease, catalytic C-terminal domain
123Survival protein SurE
71219Amidohydrolase family
213Peptidyl-tRNA hydrolase PTH2
112Double-stranded DNA-binding domain
123VIT family
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
224Translin family
235TFIIE alpha subunit
11N2,N2-dimethylguanosine tRNA methyltransferase
55BNR/Asp-box repeat
11Glycosyl hydrolase family 45
22Carbohydrate binding domain
437eIF4-gamma/eIF5/eIF2-epsilon
112SCP-2 sterol transfer family
437SAP domain
11Arsenical pump membrane protein
112CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
112Cytochrome c oxidase subunit VIa
325Glycosyl hydrolase family 30 TIM-barrel domain
112MAS20 protein import receptor
5813Melibiase
61622Pheromone A receptor
112SURF4 family
123Palmitoyl protein thioesterase
23560Kd inner membrane protein
112Josephin
112Ornithine decarboxylase antizyme
123Deuterolysin metalloprotease (M35) family
11SURF1 family
112DAD family
112Hydroxyethylthiazole kinase family
112cAMP phosphodiesterases class-II
213Phosducin
11RHO protein GDP dissociation inhibitor
5611Aminopeptidase I zinc metalloprotease (M18)
347Fungalysin metallopeptidase (M36)
123X-Pro dipeptidyl-peptidase (S15 family)
71825Permease for cytosine/purines, uracil, thiamine, allantoin
347
347Nuclear transport factor 2 (NTF2) domain
112Adenosine-deaminase (editase) domain
112Beige/BEACH domain
123DENN (AEX-3) domain
224MGS-like domain
123Repair protein Rad1/Rec1/Rad17
112Rap/ran-GAP
7714Sir2 family
448Zn-finger in ubiquitin-hydrolases and other protein
112Kinase associated domain 1
347RNA polymerases M/15 Kd subunit
213Dihydroneopterin aldolase
112Prephenate dehydrogenase
22Mannose-6-phosphate receptor
11Peptidase family M50
112Cytochrome C1 family
358PAZ domain
4711Piwi domain
112TRAF-type zinc finger
21416AT hook motif
112BAG domain
224Formin Homology 2 Domain
134SAD/SRA domain
112HAT (Half-A-TPR) repeat
224Hr1 repeat
112Growth-Arrest-Specific Protein 2 Domain
325ATP-dependent protease La (LON) substrate-binding domain
224PXA domain
112Regulatory subunit of type II PKA R-subunit
112STE like transcription factor
224SWIB/MDM2 domain
224Vacuolar sorting protein 9 (VPS9) domain
112WH2 motif
224Putative zinc finger in N-recognin (UBR box)
8412Dynamin GTPase effector domain
314GYF domain
336Methylenetetrahydrofolate reductase
213ML domain
112ATP-grasp domain
112Thymidylate kinase
5510PA domain
134Transcriptional Coactivator p15 (PC4)
347Phospholipase/Carboxylesterase
112Proteasome activator pa28 beta subunit
112RFX DNA-binding domain
538FAT domain
4711FATC domain
426S1/P1 Nuclease
112Transcription initiation factor IIA, gamma subunit, helical domain
224Transcription initiation factor IID, 18kD subunit
112TFIIF, beta subunit HTH domain
11Ubiquinol-cytochrome C reductase complex 14kD subunit
112DHHA1 domain
123Polysaccharide lyase family 8, super-sandwich domain
112Cytochrome c oxidase subunit Va
112Signal recognition particle 14kD protein
112Transcription initiation factor IID, 31kD subunit
33
112Alpha adaptin AP2, C-terminal domain
213Cytochrome oxidase c subunit VIb
22Plastocyanin-like domain
336HORMA domain
11Ubiquinol-cytochrome C reductase hinge protein
145Mitochondrial glycoprotein
538OTU-like cysteine protease
112Glycine cleavage system P-protein
91322Mycolic acid cyclopropane synthetase
246Trehalose-phosphatase
134Cell division protein 48 (CDC48), N-terminal domain
3251,3-beta-glucan synthase component
336Dolichyl-phosphate-mannose-protein mannosyltransferase
51419JmjC domain, hydroxylase
134Anion-transporting ATPase
4711jmjN domain
448SacI homology domain
22Cation transport protein
123Putative methyltransferase
235Seryl-tRNA synthetase N-terminal domain
123Chromate transporter
112Ornithine cyclodeaminase/mu-crystallin family
11Chalcone-flavanone isomerase
123Conserved carboxylase domain
112Flavoprotein
112Lecithin:cholesterol acyltransferase
112Patched family
5813RecF/RecN/SMC N terminal domain
112Competence-damaged protein
538Tim17/Tim22/Tim23/Pmp24 family
325Fasciclin domain
112Met-10+ like-protein
123CLN3 protein
347CobW/HypB/UreG, nucleotide-binding domain
11MORN repeat
11CobN/Magnesium Chelatase