PFAM Domains • Chaetomium thermophilum var thermophilum DSM 1495
Annotations/GenomesChafi1Chafu1Chagl1Chagl_1Chame1Chathe1TotalAnnotation Description
PFAMs
10,4779,60710,2547,86510,4137,69456,310
33331137 transmembrane receptor (Secretin family)
544950465440293ATPase family associated with various cellular activities (AAA)
444645424734258ABC transporter
44444424ATP synthase alpha/beta family, nucleotide-binding domain
15151514151589Elongation factor Tu GTP binding domain
12121111121472Helix-loop-helix DNA-binding domain
23232214Hsp20/alpha crystallin family
141313914972Hsp70 protein
98887848KH domain
11SH2 domain
11111223121382SH3 domain
1010109101059Actin
41263898257235Ankyrin repeat
212117PAN domain
88989648ADP-ribosylation factor family
191919182017112Eukaryotic aspartyl protease
44334321Cyclic nucleotide-binding domain
11Beta/Gamma crystallin
111115Cytochrome c
213Double-stranded RNA binding motif
433174435EF hand
1124Fe-4S binding domain
22132212Fibronectin type III domain
21222211Globin
1198109249Glutathione S-transferase, C-terminal domain
1111116Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
123Hemopexin
46565430Homeodomain
23332316lactate/malate dehydrogenase, NAD binding domain
44555528Myosin head (motor domain)
1046396839535476Cytochrome P450
17215016411715696855Protein kinase domain
15131416151386Pyridine nucleotide-disulphide oxidoreductase
262425232726151Ras family
1010121211964Response regulator receiver domain
53435121RNase H
555355615454332RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
10711118Reverse transcriptase (RNA-dependent DNA polymerase)
44434423Copper/zinc superoxide dismutase (SODC)
22222212Iron/manganese superoxide dismutases, alpha-hairpin domain
201724131910103Subtilase family
564853475727288Sugar (and other) transporter
1313121113971Thioredoxin
11Trypsin
44434423Tubulin/FtsZ family, GTPase domain
11529von Willebrand factor type A domain
252226512715166Zinc finger, C2H2 type
536328357Zinc finger, C3HC4 type (RING finger)
246474770Zinc knuckle
22222212Protein-tyrosine phosphatase
976985848438457short chain dehydrogenase
503141514718238Zinc-binding dehydrogenase
66556533Thiolase, N-terminal domain
38273229296161Beta-ketoacyl synthase, N-terminal domain
433532202Fe-2S iron-sulfur cluster binding domain
111115Papain family cysteine protease
1111116Enolase, C-terminal TIM barrel domain
77Cytochrome C and Quinol oxidase polypeptide I
101010910958Glutamine amidotransferase class-I
9101010101059TCP-1/cpn60 chaperonin family
44444424Glutamine synthetase, catalytic domain
22222111Triosephosphate isomerase
201919132117109E1-E2 ATPase
88978747Core histone H2A/H2B/H3/H4
79978545Alpha amylase, catalytic domain
1122129Phorbol esters/diacylglycerol binding domain (C1 domain)
78888948Bacterial transferase hexapeptide (six repeats)
76857538tRNA synthetases class I (I, L, M and V)
108958848Cyclin, N-terminal domain
1715181819895Carboxylesterase family
44444323DNA polymerase family B
66656433ATP synthase subunit C
53334321Peroxidase
1315111112163Beta-lactamase
33322215C-5 cytosine-specific DNA methylase
211923242318128Calcineurin-like phosphoesterase
101111811859Cellulase (glycosyl hydrolase family 5)
87778643tRNA synthetases class II (D, K and N)
393738364134225Mitochondrial carrier protein
11recA bacterial DNA recombination protein
18161613171494Aminotransferase class I and II
55695434Phosphoribosyl transferase domain
10101010101060Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
11Ribosome inactivating protein
1111116Phosphoglycerate kinase
22222212Ribosomal protein S4/S9 N-terminal domain
22222212Ribosomal protein S12/S23
111115Bacterial regulatory helix-turn-helix proteins, AraC family
1111116Chaperonin 10 Kd subunit
989139856C2 domain
898148855PH domain
1515157121377bZIP transcription factor
15141412141079Aldehyde dehydrogenase family
15215214310615061764Fungal Zn(2)-Cys(6) binuclear cluster domain
252124182320131Cytochrome b5-like Heme/Steroid binding domain
32322214Oxidoreductase molybdopterin binding domain
15121414151181Oxidoreductase NAD-binding domain
363031293221179SNF2 family N-terminal domain
22222212Ribosomal protein S7p/S5e
222121202220126Ubiquitin-conjugating enzyme
55665532Isocitrate/isopropylmalate dehydrogenase
2222210Ribosomal Proteins L2, RNA binding domain
1111116Hsp90 protein
22222212Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
1111116Dihydrofolate reductase
93875234Chitin recognition protein
1111116Cysteine-rich secretory protein family
1111116Ribosomal protein S3, C-terminal domain
3333315Cupin
32333115Annexin
1111116Eukaryotic-type carbonic anhydrase
1111116Chalcone and stilbene synthases, N-terminal domain
333333182-oxoacid dehydrogenases acyltransferase (catalytic domain)
23333317Catalase
1111116Disintegrin
62518224UDP-glucoronosyl and UDP-glucosyl transferase
78878543Aminotransferase class-III
22222212Ribosomal protein S19
1111116DNA gyrase B
34354423Thiamine pyrophosphate enzyme, central domain
33324318Lyase
22222212Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
1111116Adenylate and Guanylate cyclase catalytic domain
1111116ATP synthase delta (OSCP) subunit
1111116Orotidine 5'-phosphate decarboxylase / HUMPS family
1111116Indole-3-glycerol phosphate synthase
1121117Aromatic amino acid lyase
1111116Pyruvate kinase, barrel domain
9101111111062Kinesin motor domain
262525252524150DnaJ domain
14141413141483Proteasome subunit
2121219Major intrinsic protein
1111116ATP synthase
1111116Glycosyl hydrolase family 1
11111163'5'-cyclic nucleotide phosphodiesterase
1111116Profilin
22212211Ribosomal protein L22p/L17e
22222212Ribosomal protein L14p/L23e
8991091257Ubiquitin family
55535528Cofilin/tropomyosin-type actin-binding protein
3332331714-3-3 protein
22252215Alkaline phosphatase
33334319Zinc carboxypeptidase
222020182516121Aldo/keto reductase family
9810177859Myb-like DNA-binding domain
45444425Forkhead domain
3433316Glycosyl hydrolases family 32 N-terminal domain
22212211Ribosomal protein L16p/L10e
22222111Ribosomal protein S14p/S29e
44434423FKBP-type peptidyl-prolyl cis-trans isomerase
1111116Glutathione peroxidase
11
66566534Flavodoxin
1111116Calreticulin family
1810231423694Common central domain of tyrosinase
10910710854Aminotransferase class-V
1111116Ribonucleotide reductase, small chain
444246464442264DEAD/DEAH box helicase
807477857766459Helicase conserved C-terminal domain
1111116EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
22222212Ribosomal protein L23
2111218Pyridoxal-dependent decarboxylase, C-terminal sheet domain
1122129Ribosomal protein L5
76657637Pyridoxal-dependent decarboxylase conserved domain
33323317Citrate synthase, C-terminal domain
55555530GHMP kinases N terminal domain
55545529Biotin carboxylase, N-terminal domain
1111116Tryptophan synthase alpha chain
12911911961Pyridoxal-phosphate dependent enzyme
202018131914104NUDIX domain
54776534pfkB family carbohydrate kinase
1311118Glycosyl hydrolases family 28
121116Luciferase-like monooxygenase
22222212Ribosomal protein L3
22222212Ribosomal protein L11, RNA binding domain
13121313131074Histidine phosphatase superfamily (branch 1)
1111116Thymidylate synthase
111115Lipoxygenase
44444424ATP synthase alpha/beta chain, C terminal domain
55545529Calponin homology (CH) domain
13252316Glutamine amidotransferases class-II
22222212Ribosomal protein S15
111115Thaumatin family
22222111Fructose-1-6-bisphosphatase, N-terminal domain
1111116Ribonucleotide reductase, all-alpha domain
22222212Ribosomal protein S2
22222212SRF-type transcription factor (DNA-binding and dimerisation domain)
56646532GATA zinc finger
11111218121175Amino acid permease
55646430Prolyl oligopeptidase family
22212211Ribosomal protein L30p/L7e
65656331Histidine phosphatase superfamily (branch 2)
1111116Respiratory-chain NADH dehydrogenase, 30 Kd subunit
45764430Aconitase family (aconitate hydratase)
87779442Glycosyl hydrolase family 10
2211219Glycosyl hydrolases family 17
22222111Ribosomal protein S5, N-terminal domain
1111116Nucleoside diphosphate kinase
111115Tetraspanin family
112Galactoside-binding lectin
22222212Ribosomal protein S10p/S20e
33334319Arrestin (or S-antigen), N-terminal domain
1111116Phosphoglucose isomerase
1111116Carbohydrate phosphorylase
1111116SecY translocase
1111116Respiratory-chain NADH dehydrogenase, 49 Kd subunit
22222212Ribosomal protein L6
45446427Polyprenyl synthetase
44444323Hexokinase
191517914680Dynamin family
22222111Transcription factor TFIID (or TATA-binding protein, TBP)
33432318Rieske [2Fe-2S] domain
33Proton-conducting membrane transporter
77777742Biotin-requiring enzyme
1111116Phosphofructokinase
22222212Ribosomal protein S17
1111116Hydroxymethylglutaryl-coenzyme A reductase
33233317FGGY family of carbohydrate kinases, N-terminal domain
11Hemocyanin, copper containing domain
11114Sodium:dicarboxylate symporter family
1099710954Enoyl-CoA hydratase/isomerase
22222212Ribosomal protein S9/S16
22222212Transcription factor TFIIB repeat
87967643Cytidine and deoxycytidylate deaminase zinc-binding region
1112117Molybdopterin oxidoreductase
879288666Chromo (CHRromatin Organisation MOdifier) domain
43444423Phosphatidylinositol-specific phospholipase C, Y domain
54545629Phosphatidylinositol-specific phospholipase C, X domain
67666536D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
22222212Malic enzyme, N-terminal domain
1113PEP-utilising enzyme, mobile domain
11111166-phosphogluconate dehydrogenase, C-terminal domain
912788549Multicopper oxidase
10910910755WW domain
1211128Ribosomal RNA adenine dimethylase
112Yeast PIR protein repeat
10710310811311394638WD domain, G-beta repeat
44445425Heavy-metal-associated domain
43535323Adenylate kinase
22212211Phosphoglucomutase/phosphomannomutase, C-terminal domain
22222212Ribosomal protein S8
22212211Ribosomal protein S11
54545427LIM domain
22Matrixin
65624326Regulator of chromosome condensation (RCC1) repeat
22221211Ribosomal protein S13/S18
22223213chorismate binding enzyme
3333331860s Acidic ribosomal protein
43454424Prenyltransferase and squalene oxidase repeat
33363523Protein kinase C terminal domain
1111116Single-strand binding protein family
11Type II/IV secretion system protein
1111116S-adenosylmethionine synthetase, N-terminal domain
99988851Bromodomain
979810649Acyl-CoA dehydrogenase, C-terminal domain
13131314131278Ubiquitin carboxyl-terminal hydrolase
11114Ribosomal protein L36
123Ribonuclease T2 family
33323317HSF-type DNA-binding
33323216SRP54-type protein, GTPase domain
1111217Urease alpha-subunit, N-terminal domain
55567331Serine carboxypeptidase
88888848Phosphatidylinositol 3- and 4-kinase
1111217Transketolase, thiamine diphosphate binding domain
961099447Glycosyl hydrolases family 11
65656533Inositol monophosphatase family
44444323Glutaredoxin
22222212Isocitrate lyase family
22232213Serine hydroxymethyltransferase
1111116Iron-containing alcohol dehydrogenase
22212211Ribosomal protein L10
22333114KOW motif
111115Ribosomal protein L34
1113Ribosomal protein L33
33313316RF-1 domain
22212110Sodium:solute symporter family
1111116Imidazoleglycerol-phosphate dehydratase
1111116DNA polymerase family A
1111116IMP dehydrogenase / GMP reductase domain
1111116Glucose-6-phosphate dehydrogenase, NAD binding domain
66766637Protein phosphatase 2C
33223316Nucleotidyl transferase
33333318Carbonic anhydrase
1111116Phosphoribulokinase / Uridine kinase family
76767538Fatty acid desaturase
66666535MutS domain V
1111116Delta-aminolevulinic acid dehydratase
2121219Arginase family
66666636MCM P-loop domain
22212211Squalene/phytoene synthase
11Bacterial extracellular solute-binding proteins, family 3
1013119101063FHA domain
514348455024261AMP-binding enzyme
33433319G-protein alpha subunit
139121110964HMG (high mobility group) box
77987644His Kinase A (phospho-acceptor) domain
23222213Armadillo/beta-catenin-like repeat
181918271715114Tetratricopeptide repeat
23222213Ion transport protein
1111116DNA gyrase/topoisomerase IV, subunit A
65787740BRCA1 C Terminus (BRCT) domain
88888646Glycosyl transferases group 1
22232213Glycosyl transferase family 2
111115SAM domain (Sterile alpha motif)
1111116linker histone H1 and H5 family
1111116Ribosomal protein L7/L12 C-terminal domain
52667127Pectate lyase
32224114ribonuclease
1111217Urease, gamma subunit
43444322CoA-ligase
46344225439199Phosphopantetheine attachment site
44334321Formyl transferase
99989852Metallopeptidase family M24
232113425Leucine Rich Repeat
12711268569alpha/beta hydrolase fold
33333318RNA polymerase Rpb2, domain 6
44444424PB1 domain
22222212Staphylococcal nuclease homologue
1212129121067Rab-GTPase-TBC domain
1111116Tudor domain
1111116WH1 domain
34413318Zinc finger, ZZ type
1111116HRDC domain
76676739CBS domain
22222212Ribosomal protein L13
22222212Ribosomal protein L4/L1 family
1111116Clp protease
54425525S1 RNA binding domain
1111116HIUase/Transthyretin family
23323215AhpC/TSA family
44444424tRNA synthetases class I (W and Y)
1113UvrD/REP helicase N-terminal domain
1199410952Rhodanese-like domain
22222212Universal stress protein family
242521222716135Acetyltransferase (GNAT) family
1111116SecE/Sec61-gamma subunits of protein translocation complex
1111116C-terminal regulatory domain of Threonine dehydratase
22222212AIR synthase related protein, N-terminal domain
98798647tRNA synthetase class II core domain (G, H, P, S and T)
1111116SpoU rRNA Methylase family
32222213Tetrapyrrole (Corrin/Porphyrin) Methylases
1111116Glycosyl transferase family, a/b domain
11PDZ domain
1211117Class II Aldolase and Adducin N-terminal domain
44444424Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
55545529Fes/CIP4, and EFC/F-BAR homology domain
22252316IQ calmodulin-binding motif
22222212Phosphoinositide 3-kinase family, accessory domain (PIK domain)
33252116Phospholipase D Active site motif
47517529Regulator of G protein signaling domain
44444424GTPase-activator protein for Ras-like GTPase
44444424RasGEF domain
44444424RasGEF N-terminal motif
91091011958RhoGAP domain
66656635RhoGEF domain
54435425SPRY domain
33333318RNA polymerase Rpb1, domain 2
32322214Guanylate kinase
44454324Gelsolin repeat
34483527UBA/TS-N domain
12131014111171PHD-finger
1111116GGL domain
66666636HECT-domain (ubiquitin-transferase)
22222111Helix-hairpin-helix motif
1111116MSP (Major sperm protein) domain
43434321Ribonuclease III domain
34424421Region in Clathrin and VPS
32333317RanBP1 domain
22212211PPIC-type PPIASE domain
23222213Zn-finger in Ran binding protein and others
989158857Zinc finger C-x8-C-x5-C-x3-H type (and similar)
11B-box zinc finger
22422214Poly(ADP-ribose) polymerase catalytic domain
1111116Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
98104317491F-box domain
1111116Elongation factor 1 gamma, conserved domain
33323317Calpain family cysteine protease
1214Copper fist DNA binding domain
66666535CRAL/TRIO domain
161211713766BTB/POZ domain
2211219Ricin-type beta-trefoil lectin domain
1111116Inhibitor of Apoptosis domain
33333318Voltage gated chloride channel
44434322Caspase domain
534165437GDSL-like Lipase/Acylhydrolase
1111116Poly-adenylate binding protein, unique domain
111115POLO box duplicated region
242425202315131ABC transporter transmembrane region
36137Integrase core domain
65556431FAD binding domain
2112171513381Condensation domain
1111116S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1111116HAMP domain
22222212ribosomal L5P family C-terminus
56556633Insulinase (Peptidase family M16)
43333319Dehydrogenase E1 component
1111116Lumazine binding domain
65655532Elongation factor G C-terminus
55554428HMGL-like
44444424DnaJ central domain
112Sulfotransferase domain
24222214Starch binding domain
33313316Ribosomal protein L1p/L10e family
10910911857Cation transporting ATPase, C-terminus
10991010957Cation transporter/ATPase, N-terminus
1122219dUTPase
55665431Aconitase C-terminal domain
33333318Amino acid kinase family
1111116N-(5'phosphoribosyl)anthranilate (PRA) isomerase
37273127287157Acyl transferase domain
1111217Urease beta subunit
65636430Dihydrodipicolinate synthetase family
171616301814111haloacid dehalogenase-like hydrolase
76667436Glycosyl hydrolases family 2
1712211721795Glycosyl hydrolases family 18
1111116Proliferating cell nuclear antigen, N-terminal domain
111115Translation initiation factor IF-3, C-terminal domain
111115Acylphosphatase
1111116Adenylosuccinate synthetase
1111116Asparaginase, N-terminal
33223215Peptidase S24-like
1111127Inorganic pyrophosphatase
1414141015976Glycosyl hydrolases family 16
24222315Glycosyl hydrolases family 15
43434321NADH:flavin oxidoreductase / NADH oxidase family
222222123-hydroxyacyl-CoA dehydrogenase, C-terminal domain
1111116Glycosyl hydrolase family 20, catalytic domain
56535529HhH-GPD superfamily base excision DNA repair protein
1111116AIR carboxylase
321926222810137GMC oxidoreductase
33333217Asparagine synthase
331532333522170Fungal cellulose binding domain
66656635Septin
1111116EF-1 guanine nucleotide exchange domain
1111116Homoserine dehydrogenase
4433216Flavin-binding monooxygenase-like
44444323tRNA synthetases class I (E and Q), catalytic domain
22322112tRNA synthetases class I (R)
44433422XPG N-terminal domain
87678642Metallo-beta-lactamase superfamily
112F5/8 type C domain
22222212Choline/Carnitine o-acyltransferase
31213111Putative esterase
1111116Ferrochelatase
22222212Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
1111116Arginosuccinate synthase
111115Electron transfer flavoprotein FAD-binding domain
33333318RNB domain
66666535Dioxygenase
33323317CNH domain
22222212Diacylglycerol kinase catalytic domain
97768643Dual specificity phosphatase, catalytic domain
2222210P21-Rho-binding domain
13131312131377PX domain
22232213Ras association (RalGDS/AF-6) domain
43343623UBX domain
44444424VHS domain
1111116Phosphoinositide 3-kinase C2
23222213DAHP synthetase I family
68988746Carbon-nitrogen hydrolase
222219N-acetyltransferase
11Geminivirus Rep catalytic domain
1111116Prephenate dehydratase
34333319Syntaxin
44454425Pumilio-family RNA binding repeat
77675739Histone-like transcription factor (CBF/NF-Y) and archaeal histone
1111116Pterin binding enzyme
22222212ER lumen protein retaining receptor
22222212Glycoprotease family
1111116Histidinol dehydrogenase
44444323impB/mucB/samB family
11PMP-22/EMP/MP20/Claudin family
11
1111116Ribosomal L15
33313316Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
11Ribosomal prokaryotic L21 protein
1111116Ribosomal L28 family
1111116Ribosomal L29 protein
111115Ribosomal L39 protein
1111116Ribosomal S17
1111116Ribulose-phosphate 3 epimerase family
1111217Translationally controlled tumour protein
97788443Glycosyl hydrolase family 7
1111116RNA pseudouridylate synthase
44444424Histone deacetylase domain
33323115POT family
1111116PWWP domain
302725192917147SET domain
57645330Isochorismatase family
33333318Permease family
1111116Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
44444424XPG I-region
1111116Acetokinase family
11DNA photolyase
11NlpC/P60 family
111115Nitroreductase family
23232214Sulfatase
11111166,7-dimethyl-8-ribityllumazine synthase
1111116Ribosomal protein S16
22222212Acyl CoA binding protein
44444424Cullin family
66584736FAD binding domain
1610131212568O-methyltransferase domain
32323316EamA-like transporter family
11
88888848ThiF family
1111116Ribosomal family S4e
53555326Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
22222313Ammonium Transporter Family
55555429Sulfate permease family
1111116MATH domain
33333318Dehydratase family
2121219Transaldolase/Fructose-6-phosphate aldolase
23222213Mechanosensitive ion channel
22212211GTP cyclohydrolase II
11111163,4-dihydroxy-2-butanone 4-phosphate synthase
44444424Adaptor complexes medium subunit family
86778440Exonuclease
22333215Dipeptidyl peptidase IV (DPP IV) N-terminal region
917179153NB-ARC domain
11Lamin Tail Domain
1312131315773Glycosyl hydrolase family 3 N terminal domain
1111116Ribosomal protein L44
1111116Sodium:sulfate symporter transmembrane region
1111116DNA-dependent RNA polymerase
1111116FAD binding domain in molybdopterin dehydrogenase
11Peptidase S7, Flavivirus NS3 serine protease
1111116Glycosyl transferase family 4
2112219HCO3- transporter family
22223213Nucleosome assembly protein (NAP)
44444424Synaptobrevin
1111116GMP synthase C terminal domain
1111116Phage lysozyme
43444322Adenosine/AMP deaminase
87999648Oxidoreductase FAD-binding domain
55755128Thioesterase domain
22222212Histidine biosynthesis protein
33333318Glycosyltransferase family 20
22222111UDP-glucose/GDP-mannose dehydrogenase family, central domain
22222212Carbamoyl-phosphate synthase small chain, CPSase domain
22PAS fold
22232112Probable molybdopterin binding domain
44444