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PFAM Domains • Microsporidia
Annotations/GenomesAntlo1Enccu1Enche1Encin1Encro1Entbi1Mitdap1Nempa1Nosce1TotalAnnotation Description
337 transmembrane sweet-taste receptor of 3 GCPR
91818191821261717163ATPase family associated with various cellular activities (AAA)
10131414132511612118ABC transporter
12222342220ATP synthase alpha/beta family, nucleotide-binding domain
3766619146673Elongation factor Tu GTP binding domain
33Helix-loop-helix DNA-binding domain
44Hsp20/alpha crystallin family
33434383435Hsp70 protein
344541252241KH domain
213Methyl-accepting chemotaxis protein (MCP) signalling domain
11SH2 domain
11SH3 domain
22223112Ankyrin repeat
34433263331ADP-ribosylation factor family
11Eukaryotic aspartyl protease
222211212Cyclic nucleotide-binding domain
112Cytochrome c
43333411325EF hand
111111111184Fe-4S binding domain
11Glutathione S-transferase, C-terminal domain
111111118Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
11lactate/malate dehydrogenase, NAD binding domain
22222211216Myosin head (motor domain)
252727262635592526276Protein kinase domain
11111233114Pyridine nucleotide-disulphide oxidoreductase
8999912108983Ras family
246Response regulator receiver domain
13182018171631118152RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
358Reverse transcriptase (RNA-dependent DNA polymerase)
33Serpin (serine protease inhibitor)
111112119Iron/manganese superoxide dismutases, alpha-hairpin domain
32222192225Subtilase family
321217117Sugar (and other) transporter
33331833339Tubulin/FtsZ family, GTPase domain
11von Willebrand factor type A domain
7687699759Zinc finger, C2H2 type
1618151516111619126Zinc finger, C3HC4 type (RING finger)
211235317Zinc knuckle
1111111119Protein-tyrosine phosphatase
12233552427short chain dehydrogenase
11215Zinc-binding dehydrogenase
21111118Thiolase, N-terminal domain
11Beta-ketoacyl synthase, N-terminal domain
11111162Fe-2S iron-sulfur cluster binding domain
111111118Enolase, C-terminal TIM barrel domain
11Cytochrome C and Quinol oxidase polypeptide I
1222211112Glutamine amidotransferase class-I
888891498880TCP-1/cpn60 chaperonin family
112Glutamine synthetase, catalytic domain
111111118Triosephosphate isomerase
122225103229E1-E2 ATPase
33333164228Core histone H2A/H2B/H3/H4
11Bacterial regulatory helix-turn-helix protein, lysR family
111122210Phorbol esters/diacylglycerol binding domain (C1 domain)
1112131212Bacterial transferase hexapeptide (six repeats)
12222252220tRNA synthetases class I (I, L, M and V)
32222232220Cyclin, N-terminal domain
11Carboxylesterase family
23333433226DNA polymerase family B
1111228ATP synthase subunit C
11C-5 cytosine-specific DNA methylase
46666774551Calcineurin-like phosphoesterase
23334353228tRNA synthetases class II (D, K and N)
2020Mitochondrial carrier protein
3222242219Aminotransferase class I and II
112Phosphoribosyl transferase domain
112Sigma-54 interaction domain
12222242118Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
11111117Phosphoglycerate kinase
1111127Ribosomal protein S4/S9 N-terminal domain
111111118Ribosomal protein S12/S23
22Bacterial regulatory helix-turn-helix proteins, AraC family
11Chaperonin 10 Kd subunit
11111121110C2 domain
121122110PH domain
1111318bZIP transcription factor
22Aldehyde dehydrogenase family
11Fungal Zn(2)-Cys(6) binuclear cluster domain
111173115Cytochrome b5-like Heme/Steroid binding domain
32222152322Oxidoreductase NAD-binding domain
46667487553SNF2 family N-terminal domain
41111121113Ribosomal protein S7p/S5e
118888677871Ubiquitin-conjugating enzyme
55Isocitrate/isopropylmalate dehydrogenase
22Ribosomal Proteins L2, RNA binding domain
11111117Chitinase class I
11111141112Hsp90 protein
32211110Dihydrofolate reductase
111112119Cysteine-rich secretory protein family
21111111110Ribosomal protein S3, C-terminal domain
22Bacterial regulatory proteins, luxR family
332-oxoacid dehydrogenases acyltransferase (catalytic domain)
112Aminotransferase class-III
21111321113Ribosomal protein S19
1111111119DNA gyrase B
11Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
11111117Ferritin-like domain
112Adenylate and Guanylate cyclase catalytic domain
11ATP synthase delta (OSCP) subunit
11Bacterial DNA-binding protein
11111117Pyruvate kinase, barrel domain
26666256645Kinesin motor domain
101110111181513796DnaJ domain
91414141429121412132Proteasome subunit
1111111119Major intrinsic protein
11ATP synthase
1111153'5'-cyclic nucleotide phosphodiesterase
1111821116Ribosomal protein L22p/L17e
111112119Ribosomal protein L14p/L23e
25566566344Ubiquitin family
11111117Cofilin/tropomyosin-type actin-binding protein
11111111814-3-3 protein
11Alkaline phosphatase
11Zinc carboxypeptidase
11111128Aldo/keto reductase family
89999376767Myb-like DNA-binding domain
12222233219Forkhead domain
11Ribosomal protein L16p/L10e
1111217Ribosomal protein S14p/S29e
213FKBP-type peptidyl-prolyl cis-trans isomerase
11111111210Glutathione peroxidase
2114Common central domain of tyrosinase
1111121210Thymidine kinase
21111111110Aminotransferase class-V
11112311130Ribonucleotide reductase, small chain
81717171726351717171DEAD/DEAH box helicase
132828282828453022250Helicase conserved C-terminal domain
11111117Fructose-bisphosphate aldolase class-I
1222212113Ribosomal protein L23
1111111119Ribosomal protein L5
11Citrate synthase, C-terminal domain
222224115GHMP kinases N terminal domain
11Biotin carboxylase, N-terminal domain
235Pyridoxal-phosphate dependent enzyme
12222542121NUDIX domain
123pfkB family carbohydrate kinase
12222321116Ribosomal protein L3
111112119Ribosomal protein L11, RNA binding domain
11Histidine phosphatase superfamily (branch 1)
322111111Thymidylate synthase
12222342220ATP synthase alpha/beta chain, C terminal domain
13333223323Calponin homology (CH) domain
11111411112Glutamine amidotransferases class-II
111111118Ribosomal protein S15
112Fructose-1-6-bisphosphatase, N-terminal domain
1111211210Ribonucleotide reductase, all-alpha domain
21111121111Ribosomal protein S2
11111117SRF-type transcription factor (DNA-binding and dimerisation domain)
22222114218GATA zinc finger
111115Amino acid permease
11Prolyl oligopeptidase family
21111121111Ribosomal protein L30p/L7e
1111111119Histidine phosphatase superfamily (branch 2)
22Aconitase family (aconitate hydratase)
11111121110Ribosomal protein S5, N-terminal domain
111111118Nucleoside diphosphate kinase
111115Tetraspanin family
3216Ribosomal protein S10p/S20e
1113Arrestin (or S-antigen), N-terminal domain
2111121110Phosphoglucose isomerase
11111117SecY translocase
111111219Ribosomal protein L6
211112210Polyprenyl synthetase
1222251217Dynamin family
1111111119Transcription factor TFIID (or TATA-binding protein, TBP)
11Rieske [2Fe-2S] domain
11Phytochrome region
314Biotin-requiring enzyme
111112119Ribosomal protein S17
11111117Hydroxymethylglutaryl-coenzyme A reductase
11FGGY family of carbohydrate kinases, N-terminal domain
22Nickel-dependent hydrogenase
44Enoyl-CoA hydratase/isomerase
111112119Ribosomal protein S9/S16
12222722222Transcription factor TFIIB repeat
2121132113Cytidine and deoxycytidylate deaminase zinc-binding region
11Molybdopterin oxidoreductase
22222131217Chromo (CHRromatin Organisation MOdifier) domain
112D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
11PEP-utilising enzyme, mobile domain
112Bacterial regulatory proteins, gntR family
1111111186-phosphogluconate dehydrogenase, C-terminal domain
1111228WW domain
11111121110Ribosomal RNA adenine dimethylase
203434343419542626281WD domain, G-beta repeat
1111221110Adenylate kinase
1111116Phosphoglucomutase/phosphomannomutase, C-terminal domain
11111811116Ribosomal protein S8
111112119Ribosomal protein S11
111111118Regulator of chromosome condensation (RCC1) repeat
11111411112Ribosomal protein S13/S18
1232860s Acidic ribosomal protein
11111112110Prenyltransferase and squalene oxidase repeat
111115Protein kinase C terminal domain
11Type II/IV secretion system protein
21115S-adenosylmethionine synthetase, N-terminal domain
22Acyl-CoA dehydrogenase, C-terminal domain
2455517104557Ubiquitin carboxyl-terminal hydrolase
11Ribosomal protein L36
32222122218HSF-type DNA-binding
32222222219SRP54-type protein, GTPase domain
14444264231Phosphatidylinositol 3- and 4-kinase
111111118Transketolase, thiamine diphosphate binding domain
213Inositol monophosphatase family
11Flagella basal body rod protein
11Isocitrate lyase family
222121111Serine hydroxymethyltransferase
31111111111Ribosomal protein L10
11111231112KOW motif
11Ribosomal protein L34
112RF-1 domain
11DNA polymerase family A
1111111119Glucose-6-phosphate dehydrogenase, NAD binding domain
22Protein phosphatase 2C
11111211110Nucleotidyl transferase
112Phosphoribulokinase / Uridine kinase family
22Transcriptional regulatory protein, C terminal
32222261323MutS domain V
11Arginase family
68888898770MCM P-loop domain
11Bacterial extracellular solute-binding proteins, family 3
44FHA domain
23323262326AMP-binding enzyme
33G-protein alpha subunit
1111161113HMG (high mobility group) box
22His Kinase A (phospho-acceptor) domain
1111111119Armadillo/beta-catenin-like repeat
48868156450Tetratricopeptide repeat
1111111119DNA gyrase/topoisomerase IV, subunit A
22Binding-protein-dependent transport system inner membrane component
13323232221BRCA1 C Terminus (BRCT) domain
11111152114Glycosyl transferases group 1
111112119Glycosyl transferase family 2
11Ribosomal protein L7/L12 C-terminal domain
11Phosphopantetheine attachment site
11Formyl transferase
2222242319Metallopeptidase family M24
94109995276151Leucine Rich Repeat
2111117alpha/beta hydrolase fold
3333333324RNA polymerase Rpb2, domain 6
11EAL domain
33PB1 domain
11Staphylococcal nuclease homologue
23333233325Rab-GTPase-TBC domain
112Zinc finger, ZZ type
1113HRDC domain
123CBS domain
31111121112Ribosomal protein L13
11111221120Ribosomal protein L4/L1 family
112Clp protease
2222142318S1 RNA binding domain
11111319AhpC/TSA family
32222742226tRNA synthetases class I (W and Y)
112UvrD/REP helicase N-terminal domain
121131211Rhodanese-like domain
11Universal stress protein family
77676557656Acetyltransferase (GNAT) family
11114SecE/Sec61-gamma subunits of protein translocation complex
45555555443tRNA synthetase class II core domain (G, H, P, S and T)
11SpoU rRNA Methylase family
1111111119Tetrapyrrole (Corrin/Porphyrin) Methylases
22TonB dependent receptor
122121110Phospholipase D Active site motif
22Regulator of G protein signaling domain
111115GTPase-activator protein for Ras-like GTPase
12222131216RhoGAP domain
11111218RhoGEF domain
112SPRY domain
23333343327RNA polymerase Rpb1, domain 2
1111111119Guanylate kinase
222222113Gelsolin repeat
2223212216UBA/TS-N domain
12222173222HECT-domain (ubiquitin-transferase)
11Helix-hairpin-helix motif
11114BRCA2 repeat
11111117MSP (Major sperm protein) domain
112Ribonuclease III domain
11Region in Clathrin and VPS
11111131111RanBP1 domain
2111117PPIC-type PPIASE domain
11114Zn-finger in Ran binding protein and others
77777675457Zinc finger C-x8-C-x5-C-x3-H type (and similar)
1113B-box zinc finger
1113F-box domain
11Elongation factor 1 gamma, conserved domain
11Copper fist DNA binding domain
22CRAL/TRIO domain
121111411Ricin-type beta-trefoil lectin domain
1111111119Inhibitor of Apoptosis domain
11GDSL-like Lipase/Acylhydrolase
112Poly-adenylate binding protein, unique domain
112POLO box duplicated region
122225317ABC transporter transmembrane region
1179Integrase core domain
1222221214FAD binding domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
11HAMP domain
1111111119ribosomal L5P family C-terminus
1111115213Insulinase (Peptidase family M16)
111141110Dehydrogenase E1 component
11221261117Elongation factor G C-terminus
11111141112DnaJ central domain
21111121111Ribosomal protein L1p/L10e family
22Cation transporting ATPase, C-terminus
44Cation transporter/ATPase, N-terminus
11Aconitase C-terminal domain
11Acyl transferase domain
35555374643haloacid dehalogenase-like hydrolase
11Glycosyl hydrolases family 18
11111121110Proliferating cell nuclear antigen, N-terminal domain
11Translation initiation factor IF-3, C-terminal domain
11Adenylosuccinate synthetase
11Asparaginase, N-terminal
11112118Peptidase S24-like
111111118Inorganic pyrophosphatase
11Glycosyl hydrolases family 15
223-hydroxyacyl-CoA dehydrogenase, C-terminal domain
2111231112HhH-GPD superfamily base excision DNA repair protein
1111116Asparagine synthase
11EF-1 guanine nucleotide exchange domain
22222232219tRNA synthetases class I (E and Q), catalytic domain
11111121110tRNA synthetases class I (R)
13333223222XPG N-terminal domain
24444424432Metallo-beta-lactamase superfamily
11F5/8 type C domain
33Choline/Carnitine o-acyltransferase
11Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
11Electron transfer flavoprotein FAD-binding domain
11111121110RNB domain
111115CNH domain
11MyTH4 domain
22P21-Rho-binding domain
1111127PX domain
111115UBX domain
11121613117Pumilio-family RNA binding repeat
45565644342Histone-like transcription factor (CBF/NF-Y) and archaeal histone
11Pterin binding enzyme
1111131110ER lumen protein retaining receptor
11111131111Glycoprotease family
112impB/mucB/samB family
1111111119Ribosomal L15
1111131110Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
11Ribosomal L28 family
133111111Ribosomal L29 protein
11114Ribosomal L39 protein
21111111110Ribosomal S17
3111111110Ribulose-phosphate 3 epimerase family
11Translationally controlled tumour protein
3111111110RNA pseudouridylate synthase
22222232219Histone deacetylase domain
1111116POT family
2111135115SET domain
1111111119Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
24444233228XPG I-region
11Transposase, Mutator family
11DNA photolyase
11111117Cytosol aminopeptidase family, catalytic domain
11Ribosomal protein S16
11Acyl CoA binding protein
12222211Cullin family
22FAD binding domain
23434534331ThiF family
1111111119Ribosomal family S4e
11Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
1111116Sulfate permease family
11Uncharacterized protein family UPF0004
11Transaldolase/Fructose-6-phosphate aldolase
45444463640Mechanosensitive ion channel
31111119Adaptor complexes medium subunit family
11111117Ribosomal protein L44
11Sodium:sulfate symporter transmembrane region
11DNA-dependent RNA polymerase
11ABC 3 transport family
112Glycosyl transferase family 4
134Nucleosome assembly protein (NAP)
112Adenosine/AMP deaminase
112Oxidoreductase FAD-binding domain
2222232116Glycosyltransferase family 20
11UDP-glucose/GDP-mannose dehydrogenase family, central domain
11PAS fold
33333353127Sec1 family
22222121216GDP dissociation inhibitor
1111111119Sodium/hydrogen exchanger family
22222232219RNA polymerase Rpb3/RpoA insert domain
33Initiation factor 2 subunit family
22Electron transfer flavoprotein domain
111111511123Ribosomal S3Ae family
31111111111Ribosomal L40e family
111112119TatD related DNase
11Inhibitor of apoptosis-promoting Bax1
11Eukaryotic DNA topoisomerase I, catalytic core
1222231215Dynamin central region
116-O-methylguanine DNA methyltransferase, DNA binding domain
112Carboxyl transferase domain
22UbiA prenyltransferase family
11MarR family
22Phosphorylase superfamily
112Cys/Met metabolism PLP-dependent enzyme
23222121116ABC-2 type transporter
11Amino-transferase class IV
222212213CDP-alcohol phosphatidyltransferase
111111118ATP dependent DNA ligase domain
11Nitrite and sulphite reductase 4Fe-4S domain
31111411114Ribosomal protein S19e
1111111119Ribosomal protein S6e
44Receptor family ligand binding region
333331123334Transcription factor S-II (TFIIS)
11Surface antigen
33emp24/gp25L/p24 family/GOLD
11NifU-like domain
112Cyclin-dependent kinase regulatory subunit
11F-actin capping protein, beta subunit
121112210DNA mismatch repair protein, C-terminal domain
111115Dephospho-CoA kinase
111111118G10 protein
11Heme oxygenase
11Succinate dehydrogenase/Fumarate reductase transmembrane subunit
111142-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
1111111119DNA topoisomerase
11Elongation factor P (EF-P) OB domain
22Glucose inhibited division protein A
11Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
11111117RNA 3'-terminal phosphate cyclase
3111121103' exoribonuclease family, domain 1
1111111119tRNA-splicing ligase RtcB
21111121111tRNA pseudouridine synthase D (TruD)
123Coenzyme A transferase
44SPFH domain / Band 7 family
2222111112Cytidylyltransferase family
11111218GDA1/CD39 (nucleoside phosphatase) family
112GNS1/SUR4 family
11111218Hydroxymethylglutaryl-coenzyme A synthase N terminal
1111111119Ribosomal protein L21e
1111131110Ribosomal protein L36e
11Ribosomal protein L6e
11Phosphatidylethanolamine-binding protein
33333232325RIO1 family
1111811115Tub family
11Alanine racemase, N-terminal domain
11Uncharacterized protein family UPF0016
1113Putative RNA methylase family UPF0020
111112119PP-loop family
111112119Shwachman-Bodian-Diamond syndrome (SBDS) protein
11111218Translation initiation factor 1A / IF-1
11Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
5333346443516S rRNA methyltransferase RsmB/F
1111111119RNA polymerase Rpb5, C-terminal domain
1111122110RNA polymerase Rpb6
22232234222RNA polymerase Rpb3/Rpb11 dimerisation domain
11111117RNA polymerases N / 8 kDa subunit
11Ribosomal protein L31
111111118Ribosomal protein L31e
3111111110Ribosomal protein L34e
1111116Ribosomal protein S28e
22222222218Ribosomal protein S8e
4222223219Dihydrouridine synthase (Dus)
11ubiE/COQ5 methyltransferase family