PFAM Domains • Septoria
Annotations/GenomesSepmu1Seppo1TotalAnnotation Description
PFAMs
7,5277,17614,703
413980ATPase family associated with various cellular activities (AAA)
323466ABC transporter
448ATP synthase alpha/beta family, nucleotide-binding domain
141428Elongation factor Tu GTP binding domain
131225Helix-loop-helix DNA-binding domain
224Hsp20/alpha crystallin family
7714Hsp70 protein
9716KH domain
112SH2 domain
232346SH3 domain
9918Actin
312859Ankyrin repeat
11PAN domain
7714ADP-ribosylation factor family
111021Eukaryotic aspartyl protease
448Cyclic nucleotide-binding domain
11Cytochrome b(C-terminal)/b6/petD
112Cytochrome c
325Double-stranded RNA binding motif
191736EF hand
1124Fe-4S binding domain
426Fibronectin type III domain
112Globin
141125Glutathione S-transferase, C-terminal domain
112Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
5611Homeodomain
336lactate/malate dehydrogenase, NAD binding domain
459Myosin head (motor domain)
7463137Cytochrome P450
118111229Protein kinase domain
131326Pyridine nucleotide-disulphide oxidoreductase
232447Ras family
222143Response regulator receiver domain
213RNase H
5959118RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
224Copper/zinc superoxide dismutase (SODC)
224Iron/manganese superoxide dismutases, alpha-hairpin domain
6410Subtilase family
514495Sugar (and other) transporter
10919Thioredoxin
112Trypsin
336Tubulin/FtsZ family, GTPase domain
336von Willebrand factor type A domain
464793Zinc finger, C2H2 type
484795Zinc finger, C3HC4 type (RING finger)
314Zinc knuckle
224Protein-tyrosine phosphatase
9883181short chain dehydrogenase
494190Zinc-binding dehydrogenase
6511Thiolase, N-terminal domain
131225Beta-ketoacyl synthase, N-terminal domain
66122Fe-2S iron-sulfur cluster binding domain
112Enolase, C-terminal TIM barrel domain
22Cytochrome C and Quinol oxidase polypeptide I
11Cytochrome C oxidase subunit II, periplasmic domain
8917Glutamine amidotransferase class-I
101020TCP-1/cpn60 chaperonin family
11ATP synthase A chain
224Glutamine synthetase, catalytic domain
224Triosephosphate isomerase
121224E1-E2 ATPase
282048Core histone H2A/H2B/H3/H4
121224Alpha amylase, catalytic domain
224Phorbol esters/diacylglycerol binding domain (C1 domain)
91019Bacterial transferase hexapeptide (six repeats)
549tRNA synthetases class I (I, L, M and V)
6713Cyclin, N-terminal domain
161430Carboxylesterase family
448DNA polymerase family B
459ATP synthase subunit C
336Peroxidase
6612Beta-lactamase
336C-5 cytosine-specific DNA methylase
11NADH dehydrogenase
202141Calcineurin-like phosphoesterase
5510Cellulase (glycosyl hydrolase family 5)
7714tRNA synthetases class II (D, K and N)
383775Mitochondrial carrier protein
112recA bacterial DNA recombination protein
151732Aminotransferase class I and II
10818Phosphoribosyl transferase domain
121224Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
112Phosphoglycerate kinase
123Ribosomal protein S4/S9 N-terminal domain
224Ribosomal protein S12/S23
112Chaperonin 10 Kd subunit
131326C2 domain
171734PH domain
8816bZIP transcription factor
151530Aldehyde dehydrogenase family
123112235Fungal Zn(2)-Cys(6) binuclear cluster domain
232043Cytochrome b5-like Heme/Steroid binding domain
549Oxidoreductase molybdopterin binding domain
141125Oxidoreductase NAD-binding domain
222446SNF2 family N-terminal domain
224Ribosomal protein S7p/S5e
232245Ubiquitin-conjugating enzyme
8816Isocitrate/isopropylmalate dehydrogenase
224Ribosomal Proteins L2, RNA binding domain
112Hsp90 protein
224Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
112Chitin recognition protein
5510Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
347Cupin
224Annexin
213Eukaryotic-type carbonic anhydrase
3362-oxoacid dehydrogenases acyltransferase (catalytic domain)
448Catalase
112Disintegrin
8816Aminotransferase class-III
224Ribosomal protein S19
112DNA gyrase B
549Thiamine pyrophosphate enzyme, central domain
336Lyase
224Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
112Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
112Indole-3-glycerol phosphate synthase
112Pyruvate kinase, barrel domain
101020Kinesin motor domain
282553DnaJ domain
141428Proteasome subunit
9817Major intrinsic protein
112ATP synthase
1123'5'-cyclic nucleotide phosphodiesterase
112Profilin
112Ribosomal protein L22p/L17e
224Ribosomal protein L14p/L23e
10919Ubiquitin family
448Cofilin/tropomyosin-type actin-binding protein
22414-3-3 protein
448Alkaline phosphatase
336Zinc carboxypeptidase
211839Aldo/keto reductase family
161531Myb-like DNA-binding domain
459Forkhead domain
336Glycosyl hydrolases family 32 N-terminal domain
112Ribosomal protein L16p/L10e
224Ribosomal protein S14p/S29e
448FKBP-type peptidyl-prolyl cis-trans isomerase
112Glutathione peroxidase
224
6612Flavodoxin
112Protamine P1
112Calreticulin family
11920Common central domain of tyrosinase
9817Aminotransferase class-V
112Ribonucleotide reductase, small chain
404080DEAD/DEAH box helicase
7372145Helicase conserved C-terminal domain
112EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
224Ribosomal protein L23
112Pyridoxal-dependent decarboxylase, C-terminal sheet domain
224Ribosomal protein L5
5510Pyridoxal-dependent decarboxylase conserved domain
224Citrate synthase, C-terminal domain
5510GHMP kinases N terminal domain
7714Biotin carboxylase, N-terminal domain
112Tryptophan synthase alpha chain
111122Pyridoxal-phosphate dependent enzyme
131326NUDIX domain
6612pfkB family carbohydrate kinase
5510Glycosyl hydrolases family 28
224Luciferase-like monooxygenase
224Ribosomal protein L3
224Ribosomal protein L11, RNA binding domain
141226Histidine phosphatase superfamily (branch 1)
112Thymidylate synthase
112Lipoxygenase
448ATP synthase alpha/beta chain, C terminal domain
5510Calponin homology (CH) domain
448Glutamine amidotransferases class-II
224Ribosomal protein S15
112Thaumatin family
112Fructose-1-6-bisphosphatase, N-terminal domain
112Ribonucleotide reductase, all-alpha domain
224Ribosomal protein S2
325SRF-type transcription factor (DNA-binding and dimerisation domain)
8816GATA zinc finger
383775Amino acid permease
5510Prolyl oligopeptidase family
112Ribosomal protein L30p/L7e
9918Histidine phosphatase superfamily (branch 2)
112Respiratory-chain NADH dehydrogenase, 30 Kd subunit
459Aconitase family (aconitate hydratase)
6511Glycosyl hydrolases family 17
224Ribosomal protein S5, N-terminal domain
112Nucleoside diphosphate kinase
112Ribosomal protein S10p/S20e
224Arrestin (or S-antigen), N-terminal domain
112Phosphoglucose isomerase
112Carbohydrate phosphorylase
112SecY translocase
112Respiratory-chain NADH dehydrogenase, 49 Kd subunit
224Ribosomal protein L6
448Polyprenyl synthetase
336Hexokinase
6612Dynamin family
112Transcription factor TFIID (or TATA-binding protein, TBP)
5510Rieske [2Fe-2S] domain
33Proton-conducting membrane transporter
9817Biotin-requiring enzyme
112Phosphofructokinase
224Ribosomal protein S17
112Hydroxymethylglutaryl-coenzyme A reductase
448FGGY family of carbohydrate kinases, N-terminal domain
131124Enoyl-CoA hydratase/isomerase
224Ribosomal protein S9/S16
224Transcription factor TFIIB repeat
8816Cytidine and deoxycytidylate deaminase zinc-binding region
112Molybdopterin oxidoreductase
5510Chromo (CHRromatin Organisation MOdifier) domain
336Phosphatidylinositol-specific phospholipase C, Y domain
5510Phosphatidylinositol-specific phospholipase C, X domain
8816D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
213Malic enzyme, N-terminal domain
1126-phosphogluconate dehydrogenase, C-terminal domain
8715Multicopper oxidase
8816WW domain
112Ribosomal RNA adenine dimethylase
538Yeast PIR protein repeat
102100202WD domain, G-beta repeat
448Heavy-metal-associated domain
347Adenylate kinase
112Phosphoglucomutase/phosphomannomutase, C-terminal domain
112Ribosomal protein S8
112Ribosomal protein S11
5510LIM domain
112Regulator of chromosome condensation (RCC1) repeat
224Ribosomal protein S13/S18
11NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
224chorismate binding enzyme
33660s Acidic ribosomal protein
448Prenyltransferase and squalene oxidase repeat
7714Protein kinase C terminal domain
112Single-strand binding protein family
112S-adenosylmethionine synthetase, N-terminal domain
7613Bromodomain
11819Acyl-CoA dehydrogenase, C-terminal domain
171734Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
224Ribonuclease T2 family
336HSF-type DNA-binding
224SRP54-type protein, GTPase domain
112Urease alpha-subunit, N-terminal domain
11920Serine carboxypeptidase
8816Phosphatidylinositol 3- and 4-kinase
224Transketolase, thiamine diphosphate binding domain
112Glycosyl hydrolases family 11
448Inositol monophosphatase family
448Glutaredoxin
336Isocitrate lyase family
224Serine hydroxymethyltransferase
213Iron-containing alcohol dehydrogenase
213Ribosomal protein L10
224KOW motif
112Ribosomal protein L34
336RF-1 domain
336Sodium:solute symporter family
112Imidazoleglycerol-phosphate dehydratase
112DNA polymerase family A
112IMP dehydrogenase / GMP reductase domain
112Glucose-6-phosphate dehydrogenase, NAD binding domain
5510Protein phosphatase 2C
224Nucleotidyl transferase
224Carbonic anhydrase
112Phosphoribulokinase / Uridine kinase family
6612Fatty acid desaturase
6612MutS domain V
112Delta-aminolevulinic acid dehydratase
448Arginase family
6612MCM P-loop domain
224Squalene/phytoene synthase
8816FHA domain
11NADH-ubiquinone/plastoquinone oxidoreductase chain 6
483987AMP-binding enzyme
336G-protein alpha subunit
7613HMG (high mobility group) box
11NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
181634His Kinase A (phospho-acceptor) domain
224Armadillo/beta-catenin-like repeat
232346Tetratricopeptide repeat
325Ion transport protein
112DNA gyrase/topoisomerase IV, subunit A
8816BRCA1 C Terminus (BRCT) domain
7714Glycosyl transferases group 1
7411Glycosyl transferase family 2
112SAM domain (Sterile alpha motif)
112linker histone H1 and H5 family
112Ribosomal protein L7/L12 C-terminal domain
224Pectate lyase
112ribonuclease
112Urease, gamma subunit
448CoA-ligase
222143Phosphopantetheine attachment site
448Formyl transferase
8816Metallopeptidase family M24
141428Leucine Rich Repeat
333063alpha/beta hydrolase fold
336RNA polymerase Rpb2, domain 6
336PB1 domain
224Staphylococcal nuclease homologue
111122Rab-GTPase-TBC domain
112Tudor domain
112WH1 domain
336Zinc finger, ZZ type
112HRDC domain
11920CBS domain
224Ribosomal protein L13
224Ribosomal protein L4/L1 family
112Clp protease
448S1 RNA binding domain
112HIUase/Transthyretin family
448AhpC/TSA family
448tRNA synthetases class I (W and Y)
112UvrD/REP helicase N-terminal domain
5510Rhodanese-like domain
224Universal stress protein family
302656Acetyltransferase (GNAT) family
112SecE/Sec61-gamma subunits of protein translocation complex
112C-terminal regulatory domain of Threonine dehydratase
224AIR synthase related protein, N-terminal domain
7714tRNA synthetase class II core domain (G, H, P, S and T)
224SpoU rRNA Methylase family
224Tetrapyrrole (Corrin/Porphyrin) Methylases
112Glycosyl transferase family, a/b domain
112PDZ domain
5510Class II Aldolase and Adducin N-terminal domain
336Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
5510Fes/CIP4, and EFC/F-BAR homology domain
459IQ calmodulin-binding motif
224Phosphoinositide 3-kinase family, accessory domain (PIK domain)
5510Phospholipase D Active site motif
112Regulator of G protein signaling domain
336GTPase-activator protein for Ras-like GTPase
448RasGEF domain
448RasGEF N-terminal motif
8816RhoGAP domain
6612RhoGEF domain
224SPRY domain
336RNA polymerase Rpb1, domain 2
112Guanylate kinase
448Gelsolin repeat
11819UBA/TS-N domain
201939PHD-finger
112GGL domain
6612HECT-domain (ubiquitin-transferase)
224Helix-hairpin-helix motif
112MSP (Major sperm protein) domain
549Ribonuclease III domain
224Region in Clathrin and VPS
224RanBP1 domain
224PPIC-type PPIASE domain
123Zn-finger in Ran binding protein and others
171633Zinc finger C-x8-C-x5-C-x3-H type (and similar)
224Poly(ADP-ribose) polymerase catalytic domain
112Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
434184F-box domain
112Elongation factor 1 gamma, conserved domain
112Calpain family cysteine protease
224Copper fist DNA binding domain
5510CRAL/TRIO domain
111021BTB/POZ domain
112Inhibitor of Apoptosis domain
448Voltage gated chloride channel
224Caspase domain
639GDSL-like Lipase/Acylhydrolase
112Poly-adenylate binding protein, unique domain
112POLO box duplicated region
151631ABC transporter transmembrane region
11Integrase core domain
5510FAD binding domain
11718Condensation domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
112HAMP domain
224ribosomal L5P family C-terminus
448Insulinase (Peptidase family M16)
336Dehydrogenase E1 component
112Lumazine binding domain
6612Elongation factor G C-terminus
6511HMGL-like
448DnaJ central domain
448Starch binding domain
336Ribosomal protein L1p/L10e family
7714Cation transporting ATPase, C-terminus
7714Cation transporter/ATPase, N-terminus
123dUTPase
459Aconitase C-terminal domain
336Amino acid kinase family
112N-(5'phosphoribosyl)anthranilate (PRA) isomerase
121123Acyl transferase domain
112Urease beta subunit
224Dihydrodipicolinate synthetase family
303060haloacid dehalogenase-like hydrolase
336Glycosyl hydrolases family 2
5611Glycosyl hydrolases family 18
112Proliferating cell nuclear antigen, N-terminal domain
112Acylphosphatase
112Adenylosuccinate synthetase
112Asparaginase, N-terminal
336Peptidase S24-like
112Inorganic pyrophosphatase
10818Glycosyl hydrolases family 16
336Glycosyl hydrolases family 15
6612NADH:flavin oxidoreductase / NADH oxidase family
2463-hydroxyacyl-CoA dehydrogenase, C-terminal domain
224Glycosyl hydrolase family 20, catalytic domain
347HhH-GPD superfamily base excision DNA repair protein
112AIR carboxylase
181331GMC oxidoreductase
224Asparagine synthase
112Fungal cellulose binding domain
5510Septin
112EF-1 guanine nucleotide exchange domain
112Homoserine dehydrogenase
11Flavin-binding monooxygenase-like
336tRNA synthetases class I (E and Q), catalytic domain
112tRNA synthetases class I (R)
448XPG N-terminal domain
15823Metallo-beta-lactamase superfamily
112F5/8 type C domain
224Choline/Carnitine o-acyltransferase
112Putative esterase
112Ferrochelatase
224Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
336RNB domain
8816Dioxygenase
224CNH domain
224Diacylglycerol kinase catalytic domain
8816Dual specificity phosphatase, catalytic domain
224P21-Rho-binding domain
121224PX domain
224Ras association (RalGDS/AF-6) domain
5510UBX domain
448VHS domain
112Phosphoinositide 3-kinase C2
224DAHP synthetase I family
9918Carbon-nitrogen hydrolase
224N-acetyltransferase
112Prephenate dehydratase
448Syntaxin
112Pentapeptide repeats (8 copies)
5510Pumilio-family RNA binding repeat
5510Histone-like transcription factor (CBF/NF-Y) and archaeal histone
112Pterin binding enzyme
224ER lumen protein retaining receptor
224tRNA N6-adenosine threonylcarbamoyltransferase
112Histidinol dehydrogenase
448impB/mucB/samB family
112
112Ribosomal L15
112Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal L28 family
112Ribosomal L29 protein
112Ribosomal L39 protein
112Ribosomal S17
112Ribulose-phosphate 3 epimerase family
112Translationally controlled tumour protein
112RNA pseudouridylate synthase
448Histone deacetylase domain
448POT family
112PWWP domain
131326SET domain
10818Isochorismatase family
459Permease family
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
5510XPG I-region
112Acetokinase family
437DNA photolyase
336Sulfatase
1126,7-dimethyl-8-ribityllumazine synthase
112Ribosomal protein S16
224Acyl CoA binding protein
437Cullin family
121123FAD binding domain
538O-methyltransferase domain
6410EamA-like transporter family
224
8715ThiF family
112Ribosomal family S4e
235Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
437Ammonium Transporter Family
437Sulfate permease family
112MATH domain
336Dehydratase family
112Transaldolase/Fructose-6-phosphate aldolase
325Mechanosensitive ion channel
224GTP cyclohydrolase II
1123,4-dihydroxy-2-butanone 4-phosphate synthase
448Adaptor complexes medium subunit family
5510Exonuclease
224Dipeptidyl peptidase IV (DPP IV) N-terminal region
101020Glycosyl hydrolase family 3 N terminal domain
112Ribosomal protein L44
145DNA-dependent RNA polymerase
112FAD binding domain in molybdopterin dehydrogenase
112Glycosyl transferase family 4
336HCO3- transporter family
224Nucleosome assembly protein (NAP)
448Synaptobrevin
112GMP synthase C terminal domain
55LAGLIDADG endonuclease
5510Adenosine/AMP deaminase
9716Oxidoreductase FAD-binding domain
5510Thioesterase domain
224Histidine biosynthesis protein
336Glycosyltransferase family 20
213UDP-glucose/GDP-mannose dehydrogenase family, central domain
224Carbamoyl-phosphate synthase small chain, CPSase domain
336PAS fold
224Probable molybdopterin binding domain
448Sec1 family
224GDP dissociation inhibitor
6612Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
448Initiation factor 2 subunit family
224Electron transfer flavoprotein domain
112Uricase
112Ribosomal S3Ae family
112Ribosomal L27 protein
112GTP1/OBG
224Gamma-glutamyltranspeptidase
112GrpE
224TatD related DNase
112Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
235Dynamin central region
2136-O-methylguanine DNA methyltransferase, DNA binding domain
336Bacteriorhodopsin-like protein
336Carboxyl transferase domain
336UbiA prenyltransferase family
6511Endoribonuclease L-PSP
5611Cys/Met metabolism PLP-dependent enzyme
9716Glycosyl hydrolases family 31
112NADH ubiquinone oxidoreductase, 20 Kd subunit
8917ABC-2 type transporter
5510Amino-transferase class IV
5510CDP-alcohol phosphatidyltransferase
112Calpain large subunit, domain III
437ATP dependent DNA ligase domain
8816FMN-dependent dehydrogenase
112Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
3253-beta hydroxysteroid dehydrogenase/isomerase family
112Glycosyl hydrolases family 38 N-terminal domain
224Nitrite and sulphite reductase 4Fe-4S domain
6410Cutinase
112Ribosomal protein S18
112Clathrin light chain
112Galactose-1-phosphate uridyl transferase, N-terminal domain
448Ubiquitin carboxyl-terminal hydrolase, family 1
112Ribosomal protein S19e
112Ribosomal protein S6e
549Transcription factor S-II (TFIIS)
112Omp85 superfamily domain
448emp24/gp25L/p24 family/GOLD
112NifU-like domain
112Cyclin-dependent kinase regulatory subunit
224Asparaginase
11Dihydrodipicolinate reductase, N-terminus
112F-actin capping protein, beta subunit
224Fructose-bisphosphate aldolase class-II
336Semialdehyde dehydrogenase, NAD binding domain
235DNA mismatch repair protein, C-terminal domain
325Alpha-L-fucosidase
112Dephospho-CoA kinase
112MAPEG family
112G10 protein
213Succinate dehydrogenase/Fumarate reductase transmembrane subunit
112DNA topoisomerase
112Glucose inhibited division protein A
112Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
224RNA 3'-terminal phosphate cyclase
4483' exoribonuclease family, domain 1
112tRNA pseudouridine synthase D (TruD)
224Coenzyme A transferase
448SPFH domain / Band 7 family
336Cytidylyltransferase family
112Formamidopyrimidine-DNA glycosylase N-terminal domain
224GDA1/CD39 (nucleoside phosphatase) family
224GNS1/SUR4 family
112Hydroxymethylglutaryl-coenzyme A synthase N terminal
336Inosine-uridine preferring nucleoside hydrolase
112Ribosomal protein L21e
112Ribosomal protein L36e
112Ribosomal protein L6e
213Phosphatidylethanolamine-binding protein
112
235RIO1 family
112Alanine racemase, N-terminal domain
112Uncharacterized protein family UPF0016
123Putative RNA methylase family UPF0020
224PP-loop family
112Shwachman-Bodian-Diamond syndrome (SBDS) protein
112SNO glutamine amidotransferase family
224Translation initiation factor 1A / IF-1
112Asp/Glu/Hydantoin racemase
224Copper amine oxidase, enzyme domain
112Dihydroorotate dehydrogenase
224Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
112GPR1/FUN34/yaaH family
112Macrophage migration inhibitory factor (MIF)
336
43716S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
448RNA polymerase Rpb3/Rpb11 dimerisation domain
112RNA polymerases N / 8 kDa subunit
11Peptidyl-tRNA hydrolase
112Ribosomal protein L17
112Ribosomal protein L31e
112Ribosomal protein L34e
112Ribosomal protein S28e
224Ribosomal protein S8e
123Shikimate kinase
112Trehalase
123Uncharacterized protein family UPF0029
448Dihydrouridine synthase (Dus)
112Uroporphyrinogen decarboxylase (URO-D)
112ubiE/COQ5 methyltransferase family
112NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
325Beta-eliminating lyase
112Adenylate cyclase associated (CAP) N terminal
224Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
5510Clathrin adaptor complex small chain
112Coproporphyrinogen III oxidase
112Dehydroquinase class II
112Dynein light chain type 1
336Ergosterol biosynthesis ERG4/ERG24 family
112DNA/RNA non-specific endonuclease
336Formate/nitrite transporter
213GTP cyclohydrolase I
448HIT domain
224Indoleamine 2,3-dioxygenase
112Mannitol dehydrogenase Rossmann domain
112Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
6612Oxysterol-binding protein
224Phosphomannose isomerase type I
224Protein prenyltransferase alpha subunit repeat
6511Pyridoxamine 5'-phosphate oxidase
224Membrane dipeptidase (Peptidase family M19)
112Ribosomal protein L19
224Ribosomal protein L24e
112Ribosomal protein L35Ae
5510Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
112Ribosomal protein S21e
112Ribosomal protein S7e
336Translation initiation factor SUI1
112Putative undecaprenyl diphosphate synthase
112Carbohydrate kinase
112Thioredoxin-like [2Fe-2S] ferredoxin
112SAICAR synthetase
437Xylose isomerase-like TIM barrel
213Alanine dehydrogenase/PNT, C-terminal domain
336Aldose 1-epimerase
112Chorismate synthase
224Cytochrome c/c1 heme lyase
403474FAD dependent oxidoreductase
112F-actin capping protein alpha subunit
112Formate--tetrahydrofolate ligase
112Fibrillarin
112Malate synthase
112Ribosomal protein L19e
112Ribosomal protein S24e
112Ribosomal protein S26e
112TEA/ATTS domain
224Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1127,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
112Phosphoenolpyruvate carboxykinase
112Ribosomal protein L13e
112Telomere recombination
112Glycosyl hydrolases family 35
437CAP-Gly domain
112
112Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
112Creatinase/Prolidase N-terminal domain
527DSBA-like thioredoxin domain
10818Peroxidase, family 2
123Pterin 4 alpha carbinolamine dehydratase
112mRNA capping enzyme, catalytic domain
101020OB-fold nucleic acid binding domain
6511Kelch motif
11Lipoprotein amino terminal region
112Ribonuclease HII
5510FYVE zinc finger
1125'-3' exonuclease, C-terminal SAM fold
11DHH family
448Sec7 domain
201535NAD dependent epimerase/dehydratase family
213Porphobilinogen deaminase, dipyromethane cofactor binding domain
224SIS domain
224Phosphate transporter family
336ARID/BRIGHT DNA binding domain
22Collagen triple helix repeat (20 copies)
112Clathrin propeller repeat
7714JAB1/Mov34/MPN/PAD-1 ubiquitin protease
141428PCI domain
112tRNA synthetases class I (C) catalytic domain
9716Oxidoreductase family, NAD-binding Rossmann fold
224tRNA synthetases class II core domain (F)
112tRNA synthetases class II (A)
5510Putative GTPase activating protein for Arf
224tRNA pseudouridine synthase
224ENTH domain
112Reprolysin (M12B) family zinc metalloprotease
314NF-X1 type zinc finger
161632LSM domain
336R3H domain
232144Amidase
5510BAH domain
112AN1-like Zinc finger
549Peptidase family M3
336Peptidase family M1 domain
224Peptidase family M41
224Peptidase family M48
112Acetohydroxy acid isomeroreductase, catalytic domain
112Low molecular weight phosphotyrosine protein phosphatase
112MAGE family
11Mucin-like glycoprotein
336Eukaryotic porin
11GRIP domain
112Skp1 family, dimerisation domain
336Cytidylyltransferase-like
112Pyroglutamyl peptidase
448PUA domain
112Class-II DAHP synthetase family
448LysM domain
448S4 domain
112PWI domain
112Proprotein convertase P-domain
6612IBR domain, a half RING-finger domain
325Type I 3-dehydroquinase
325Shikimate / quinate 5-dehydrogenase
131225Transmembrane amino acid transporter protein
112Frataxin-like domain
112GXGXG motif
201737FAD binding domain
112V-type ATPase 116kDa subunit family
6612Glycosyl transferase family 8
112Phosphoribosyl-AMP cyclohydrolase
112Phosphoribosyl-ATP pyrophosphohydrolase
336Phosphatidylinositol-4-phosphate 5-Kinase
224Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
112Respiratory-chain NADH dehydrogenase 51 Kd subunit
336ATP-NAD kinase
224Iron-sulphur cluster biosynthesis
639Polysaccharide deacetylase
6612DHHC palmitoyltransferase
9918Glycosyl hydrolase family 47
7613PPR repeat
112Adenosylmethionine decarboxylase
77GIY-YIG catalytic domain
6612CorA-like Mg2+ transporter protein
7714Cation efflux family
8816Peptidase family M20/M25/M40
7714Acyltransferase
347MatE
448DnaJ C terminal domain
448Fumarylacetoacetate (FAA) hydrolase family
11Pyruvate ferredoxin/flavodoxin oxidoreductase
112Spermine/spermidine synthase domain
211839FAD binding domain
112Natural resistance-associated macrophage protein
7714PAP2 superfamily
336Aminomethyltransferase folate-binding domain
336MaoC like domain
224Adenylylsulphate kinase
7714G-patch domain
112Putative tRNA binding domain
5510GAF domain
3366-phosphofructo-2-kinase
112NifU-like N terminal domain
101020Flavin containing amine oxidoreductase
112Cyclin M transmembrane N-terminal domain
112Glycine cleavage H-protein
336
112Ribosomal protein S27a
8816Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
112Chitin binding Peritrophin-A domain
112I/LWEQ domain
2243'-5' exonuclease
224Proline dehydrogenase
448MutS domain I
112Peptide methionine sulfoxide reductase
112Hpt domain
235Choline/ethanolamine kinase
112ATP phosphoribosyltransferase
91221Phosphotransferase enzyme family
112ATPase domain predominantly from Archaea
112SelR domain
336Chitin synthase
112Conserved region in glutamate synthase
2244'-phosphopantetheinyl transferase superfamily
112Peptidase C13 family
336Eukaryotic initiation factor 4E
112Ribosomal protein L32
112Myo-inositol-1-phosphate synthase
224Macro domain
235Type I phosphodiesterase / nucleotide pyrophosphatase
112Ribosomal protein S27
112Glycosyl hydrolase family 12
112Metalloenzyme superfamily
549Proteolipid membrane potential modulator
112SOR/SNZ family
112Riboflavin kinase
112
448Rhomboid family
8715Sodium/calcium exchanger protein
224Queuine tRNA-ribosyltransferase
224UTP--glucose-1-phosphate uridylyltransferase
112Transcriptional regulator
336Smr domain
112IPP transferase
224Cobalamin-independent synthase, Catalytic domain
336BolA-like protein
112Ham1 family
336FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
112Nucleoside transporter
7815Patatin-like phospholipase
336Lysophospholipase catalytic domain
549Dienelactone hydrolase family
336STAS domain
112Poly A polymerase head domain
112tRNA (Guanine-1)-methyltransferase
112ATP-sulfurylase
112Importin beta binding domain
112Toprim domain
7613MYND finger
112Glycosyltransferase family 25 (LPS biosynthesis protein)
213Acyl-CoA oxidase
213Acyltransferase family
112Sodium Bile acid symporter family
2243-dehydroquinate synthase
224Lipase (class 3)
112Ribosome recycling factor
112Na+ dependent nucleoside transporter N-terminus
112UreD urease accessory protein
112Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
112Ribosomal L22e protein family
112Ribosomal L27e protein family
112Ribosomal L28e protein family
112Ribosomal L29e protein family
112Ribosomal L37ae protein family
112Ribosomal L38e protein family
112Ribosomal L32p protein family
112NIF3 (NGG1p interacting factor 3)
112Alternative oxidase
112DeoC/LacD family aldolase
336Glycolipid 2-alpha-mannosyltransferase
151328Ferric reductase like transmembrane component
336snoRNA binding domain, fibrillarin
112[2Fe-2S] binding domain
112Surp module
112AICARFT/IMPCHase bienzyme
1125-formyltetrahydrofolate cyclo-ligase family
112ATP synthase subunit D
112Chorismate mutase type II
6612WSC domain
112IPT/TIG domain
112Transglutaminase-like superfamily
6511ACT domain
224DIL domain
123FF domain
224NAC domain
235Proteasome/cyclosome repeat
336MOZ/SAS family
112Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
224Putative diphthamide synthesis protein
112Domain of unknown function UPF0086
112AMMECR1
112RibD C-terminal domain
224Domain found in IF2B/IF5
112Memo-like protein
112RNase P subunit p30
112EVE domain
112Iron-sulfur cluster assembly protein
112RNA 2'-phosphotransferase, Tpt1 / KptA family
112Uncharacterised protein family UPF0047
112DNA primase small subunit
112Rpp14/Pop5 family
112Diphthamide synthase
112Ribosomal protein L37e
224Nucleotidyltransferase domain
112Thiamine-binding protein
112eIF-6 family
8816Glycosyl hydrolase family 3 C-terminal domain
112Deoxyhypusine synthase
448Prefoldin subunit
112SRP19 protein
10102050S ribosome-binding GTPase
112Ribosomal protein L14
112Uncharacterised protein family UPF0052
112Protein of unknown function DUF89
112TRAM domain
112Integral membrane protein DUF92
112Thi4 family
112ArgJ family
336DJ-1/PfpI family
347HD domain
112MoaC family
336Hydantoinase/oxoprolinase
123tRNA intron endonuclease, catalytic C-terminal domain
112Survival protein SurE
1123-octaprenyl-4-hydroxybenzoate carboxy-lyase
8816Amidohydrolase family
112Peptidyl-tRNA hydrolase PTH2
112Double-stranded DNA-binding domain
224Mitochondrial biogenesis AIM24
224VIT family
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
224Translin family
112TFIIE alpha subunit
112N2,N2-dimethylguanosine tRNA methyltransferase
213BNR/Asp-box repeat
112eIF4-gamma/eIF5/eIF2-epsilon
112SCP-2 sterol transfer family
7512SAP domain
112CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
112Cytochrome c oxidase subunit VIa
213Glycosyl hydrolase family 30 TIM-barrel domain
112MAS20 protein import receptor
213Melibiase
112Aromatic-di-Alanine (AdAR) repeat
112Pheromone A receptor
112SURF4 family
112Palmitoyl protein thioesterase
11260Kd inner membrane protein
213Deuterolysin metalloprotease (M35) family
112SURF1 family
112DAD family
112Hydroxyethylthiazole kinase family
112cAMP phosphodiesterases class-II
213Phosducin
112RHO protein GDP dissociation inhibitor
224Aminopeptidase I zinc metalloprotease (M18)
112Fungalysin metallopeptidase (M36)
123X-Pro dipeptidyl-peptidase (S15 family)
101020Permease for cytosine/purines, uracil, thiamine, allantoin
336
224Nuclear transport factor 2 (NTF2) domain
112Adenosine-deaminase (editase) domain
112Beige/BEACH domain
224DENN (AEX-3) domain
224MGS-like domain
112Repair protein Rad1/Rec1/Rad17
112Rap/ran-GAP
5510Sir2 family
224Zn-finger in ubiquitin-hydrolases and other protein
112Kinase associated domain 1
213RNA polymerases M/15 Kd subunit
11Dihydroneopterin aldolase
112Cytochrome C1 family
224PAZ domain
336Piwi domain
13922AT hook motif
112BAG domain
112Formin Homology 2 Domain
112SAD/SRA domain
336HAT (Half-A-TPR) repeat
224Hr1 repeat
112Growth-Arrest-Specific Protein 2 Domain
336ATP-dependent protease La (LON) substrate-binding domain
336PXA domain
112Regulatory subunit of type II PKA R-subunit
112STE like transcription factor
224SWIB/MDM2 domain
336Vacuolar sorting protein 9 (VPS9) domain
336WH2 motif
224Putative zinc finger in N-recognin (UBR box)
235Dynamin GTPase effector domain
224GYF domain
11BTB/POZ domain
224Methylenetetrahydrofolate reductase
112ML domain
112ATP-grasp domain
112Thymidylate kinase
7714PA domain
112Transcriptional Coactivator p15 (PC4)
437Phospholipase/Carboxylesterase
11NAD(P) transhydrogenase beta subunit
112RFX DNA-binding domain
224FAT domain
448FATC domain
224S1/P1 Nuclease
112Transcription initiation factor IIA, gamma subunit, helical domain
224Transcription initiation factor IID, 18kD subunit
112TFIIF, beta subunit HTH domain
112Ubiquinol-cytochrome C reductase complex 14kD subunit
112DHHA1 domain
112Cytochrome c oxidase subunit Va
112Signal recognition particle 14kD protein
112Transcription initiation factor IID, 31kD subunit
448
112Alpha adaptin AP2, C-terminal domain
112Cytochrome oxidase c subunit VIb
336HORMA domain
112Ubiquinol-cytochrome C reductase hinge protein
112Mitochondrial glycoprotein
336OTU-like cysteine protease
112Glycine cleavage system P-protein
224Mycolic acid cyclopropane synthetase
224Trehalose-phosphatase
213Cell division protein 48 (CDC48), N-terminal domain
1121,3-beta-glucan synthase component
336Dolichyl-phosphate-mannose-protein mannosyltransferase
5510JmjC domain, hydroxylase
112Anion-transporting ATPase
224jmjN domain
448SacI homology domain
112Cation transport protein
123Putative methyltransferase
112MoaE protein
224Seryl-tRNA synthetase N-terminal domain
112Conserved carboxylase domain
224Flavoprotein
11Beta-galactosidase
112Lecithin:cholesterol acyltransferase
112Transferase family
112Patched family
5510RecF/RecN/SMC N terminal domain
112Competence-damaged protein
437Tim17/Tim22/Tim23/Pmp24 family
213Fasciclin domain
112Met-10+ like-protein
112CLN3 protein
336CobW/HypB/UreG, nucleotide-binding domain
112MORN repeat
112Ribose/Galactose Isomerase
224CoA-transferase family III
112Oligosaccharyl transferase STT3 subunit
112CPBP intramembrane metalloprotease
282755Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
7714ZIP Zinc transporter
112CrcB-like protein, Camphor Resistance (CrcB)
224Hydantoinase B/oxoprolinase
112NAD synthase
112Ppx/GppA phosphatase family
3363-oxo-5-alpha-steroid 4-dehydrogenase
112Maf-like protein
112Ketopantoate hydroxymethyltransferase
112Acetyl-CoA hydrolase/transferase N-terminal domain
112Acyl-CoA thioesterase
5510Ketopantoate reductase PanE/ApbA
112Cyanate lyase C-terminal domain
224OsmC-like protein
112Pantoate-beta-alanine ligase
112Homocysteine S-methyltransferase
112D-Tyr-tRNA(Tyr) deacylase
112Thiamine monophosphate synthase
336Uncharacterised ACR, YagE family COG1723
112GlcNAc-PI de-N-acetylase
112SOS response associated peptidase (SRAP)
11Glycerate kinase family
112ThiS family
112Putative RNA methyltransferase
11Uroporphyrinogen-III synthase HemD
112Malate/L-lactate dehydrogenase
112ATP-dependent Clp protease adaptor protein ClpS
112Carboxyltransferase domain, subdomain A and B
314Carboxymuconolactone decarboxylase family
112Cytochrome oxidase assembly protein
33