PFAM Domains • Cryptomycota
Annotations/GenomesRozal1_1Rozal_SC1TotalAnnotation Description
PFAMs
4,6064,3168,922
2137 transmembrane receptor (rhodopsin family)
65117 transmembrane sweet-taste receptor of 3 GCPR
383977ATPase family associated with various cellular activities (AAA)
343468ABC transporter
448ATP synthase alpha/beta family, nucleotide-binding domain
161228Elongation factor Tu GTP binding domain
8917Helix-loop-helix DNA-binding domain
5712Hsp20/alpha crystallin family
7714Hsp70 protein
5611KH domain
282452SH3 domain
91019Actin
6775142Ankyrin repeat
7916ADP-ribosylation factor family
224Eukaryotic aspartyl protease
8816Cyclic nucleotide-binding domain
112Cytochrome c
224Double-stranded RNA binding motif
272754EF hand
114Fe-4S binding domain
325Glutathione S-transferase, C-terminal domain
112Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
8614Homeodomain
213lactate/malate dehydrogenase, NAD binding domain
5611Myosin head (motor domain)
6612Cytochrome P450
116136252Protein kinase domain
9817Pyridine nucleotide-disulphide oxidoreductase
242347Ras family
9716Response regulator receiver domain
3811RNase H
5550105RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
44Reverse transcriptase (RNA-dependent DNA polymerase)
11Copper/zinc superoxide dismutase (SODC)
224Iron/manganese superoxide dismutases, alpha-hairpin domain
91120Subtilase family
213Sugar (and other) transporter
9817Thioredoxin
112Trefoil (P-type) domain
112Trypsin
8715Tubulin/FtsZ family, GTPase domain
182240Zinc finger, C2H2 type
263157Zinc finger, C3HC4 type (RING finger)
151025Zinc knuckle
213Protein-tyrosine phosphatase
101020short chain dehydrogenase
5510Zinc-binding dehydrogenase
448Thiolase, N-terminal domain
112Beta-ketoacyl synthase, N-terminal domain
3362Fe-2S iron-sulfur cluster binding domain
112Enolase, C-terminal TIM barrel domain
112Cytochrome C and Quinol oxidase polypeptide I
112Cytochrome C oxidase subunit II, periplasmic domain
112Glutamine amidotransferase class-I
121325TCP-1/cpn60 chaperonin family
112Glutamine synthetase, catalytic domain
11Triosephosphate isomerase
141226E1-E2 ATPase
181533Core histone H2A/H2B/H3/H4
112Alpha amylase, catalytic domain
224Phorbol esters/diacylglycerol binding domain (C1 domain)
549Bacterial transferase hexapeptide (six repeats)
437tRNA synthetases class I (I, L, M and V)
8816Cyclin, N-terminal domain
112Carboxylesterase family
437DNA polymerase family B
426ATP synthase subunit C
336Peroxidase
224C-5 cytosine-specific DNA methylase
121123Calcineurin-like phosphoesterase
224Cellulase (glycosyl hydrolase family 5)
5611tRNA synthetases class II (D, K and N)
292655Mitochondrial carrier protein
7714Aminotransferase class I and II
5510Phosphoribosyl transferase domain
121123Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
112Phosphoglycerate kinase
112Ribosomal protein S4/S9 N-terminal domain
112Ribosomal protein S12/S23
112Chaperonin 10 Kd subunit
131225C2 domain
221537PH domain
213bZIP transcription factor
336Aldehyde dehydrogenase family
112Fungal Zn(2)-Cys(6) binuclear cluster domain
151328Cytochrome b5-like Heme/Steroid binding domain
7512Oxidoreductase NAD-binding domain
171532SNF2 family N-terminal domain
112Ribosomal protein S7p/S5e
161632Ubiquitin-conjugating enzyme
459Isocitrate/isopropylmalate dehydrogenase
112Ribosomal Proteins L2, RNA binding domain
224Chitinase class I
336Hsp90 protein
112Dihydrofolate reductase
6511Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
3362-oxoacid dehydrogenases acyltransferase (catalytic domain)
224Disintegrin
112Aminotransferase class-III
123Ribosomal protein S19
112DNA gyrase B
112Thiamine pyrophosphate enzyme, central domain
224Lyase
224Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
8816Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
347Pyruvate kinase, barrel domain
181836Kinesin motor domain
232346DnaJ domain
141327Proteasome subunit
112Major intrinsic protein
112ATP synthase
88163'5'-cyclic nucleotide phosphodiesterase
11Profilin
112Ribosomal protein L22p/L17e
213Ribosomal protein L14p/L23e
101020Ubiquitin family
224Cofilin/tropomyosin-type actin-binding protein
22414-3-3 protein
224Alkaline phosphatase
112Zinc carboxypeptidase
224Aldo/keto reductase family
11920Myb-like DNA-binding domain
448Forkhead domain
123Ribosomal protein S14p/S29e
448FKBP-type peptidyl-prolyl cis-trans isomerase
112Glutathione peroxidase
11
6511Flavodoxin
224Calreticulin family
5510Common central domain of tyrosinase
112Thymidine kinase
112Aminotransferase class-V
112Ribonucleotide reductase, small chain
433679DEAD/DEAH box helicase
6855123Helicase conserved C-terminal domain
112Fructose-bisphosphate aldolase class-I
235Ribosomal protein L23
112Pyridoxal-dependent decarboxylase, C-terminal sheet domain
112Ribosomal protein L5
112Pyridoxal-dependent decarboxylase conserved domain
224Citrate synthase, C-terminal domain
213GHMP kinases N terminal domain
213Biotin carboxylase, N-terminal domain
448Pyridoxal-phosphate dependent enzyme
6511NUDIX domain
224pfkB family carbohydrate kinase
224Ribosomal protein L3
112Ribosomal protein L11, RNA binding domain
224Histidine phosphatase superfamily (branch 1)
112Thymidylate synthase
448ATP synthase alpha/beta chain, C terminal domain
5611Calponin homology (CH) domain
224Glutamine amidotransferases class-II
112Ribosomal protein S15
112Fructose-1-6-bisphosphatase, N-terminal domain
112Ribonucleotide reductase, all-alpha domain
224Ribosomal protein S2
224SRF-type transcription factor (DNA-binding and dimerisation domain)
51015GATA zinc finger
5510Amino acid permease
8816Prolyl oligopeptidase family
112Ribosomal protein L30p/L7e
224Histidine phosphatase superfamily (branch 2)
112Aconitase family (aconitate hydratase)
224Ribosomal protein S5, N-terminal domain
448Nucleoside diphosphate kinase
213Tetraspanin family
112Ribosomal protein S10p/S20e
112Phosphoglucose isomerase
112Carbohydrate phosphorylase
11SecY translocase
224Ribosomal protein L6
11Polyprenyl synthetase
112Hexokinase
448Dynamin family
112Biopterin-dependent aromatic amino acid hydroxylase
112Transcription factor TFIID (or TATA-binding protein, TBP)
112Rieske [2Fe-2S] domain
538Biotin-requiring enzyme
112Phosphofructokinase
112Ribosomal protein S17
112Hydroxymethylglutaryl-coenzyme A reductase
112FGGY family of carbohydrate kinases, N-terminal domain
347FERM central domain
6612Enoyl-CoA hydratase/isomerase
213Ribosomal protein S9/S16
224Transcription factor TFIIB repeat
448Cytidine and deoxycytidylate deaminase zinc-binding region
101626Chromo (CHRromatin Organisation MOdifier) domain
112D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1126-phosphogluconate dehydrogenase, C-terminal domain
448WW domain
224Ribosomal RNA adenine dimethylase
137132269WD domain, G-beta repeat
325Heavy-metal-associated domain
336Adenylate kinase
224Phosphoglucomutase/phosphomannomutase, C-terminal domain
112Ribosomal protein S8
224Ribosomal protein S11
134LIM domain
224Regulator of chromosome condensation (RCC1) repeat
112Ribosomal protein S13/S18
33660s Acidic ribosomal protein
11CUB domain
336Prenyltransferase and squalene oxidase repeat
61016Protein kinase C terminal domain
112S-adenosylmethionine synthetase, N-terminal domain
9817Bromodomain
9918Acyl-CoA dehydrogenase, C-terminal domain
151732Ubiquitin carboxyl-terminal hydrolase
224HSF-type DNA-binding
224SRP54-type protein, GTPase domain
11819Phosphatidylinositol 3- and 4-kinase
112Transketolase, thiamine diphosphate binding domain
112Inositol monophosphatase family
336Glutaredoxin
112Isocitrate lyase family
224Serine hydroxymethyltransferase
224Ribosomal protein L10
437KOW motif
11Ribosomal protein L34
112RF-1 domain
112DNA polymerase family A
112Glucose-6-phosphate dehydrogenase, NAD binding domain
314Protein phosphatase 2C
325Nucleotidyl transferase
224Phosphoribulokinase / Uridine kinase family
336Fatty acid desaturase
549MutS domain V
112Delta-aminolevulinic acid dehydratase
112Arginase family
121022MCM P-loop domain
7714FHA domain
9817AMP-binding enzyme
448G-protein alpha subunit
549HMG (high mobility group) box
11Cytochrome c oxidase subunit III
5510His Kinase A (phospho-acceptor) domain
6713Armadillo/beta-catenin-like repeat
252146Tetratricopeptide repeat
549Ion transport protein
112DNA gyrase/topoisomerase IV, subunit A
111021BRCA1 C Terminus (BRCT) domain
8614Glycosyl transferases group 1
325Glycosyl transferase family 2
437SAM domain (Sterile alpha motif)
112Ribosomal protein L7/L12 C-terminal domain
325CoA-ligase
112Phosphopantetheine attachment site
11Formyl transferase
7613Metallopeptidase family M24
463985Leucine Rich Repeat
7512alpha/beta hydrolase fold
336RNA polymerase Rpb2, domain 6
213PB1 domain
224Staphylococcal nuclease homologue
7916Rab-GTPase-TBC domain
112Tudor domain
112WH1 domain
112Zinc finger, ZZ type
112HRDC domain
7815CBS domain
224Ribosomal protein L13
224Ribosomal protein L4/L1 family
11Clp protease
448S1 RNA binding domain
426AhpC/TSA family
448tRNA synthetases class I (W and Y)
5510Rhodanese-like domain
224Universal stress protein family
8715Acetyltransferase (GNAT) family
112SecE/Sec61-gamma subunits of protein translocation complex
11C-terminal regulatory domain of Threonine dehydratase
6410tRNA synthetase class II core domain (G, H, P, S and T)
336SpoU rRNA Methylase family
112Tetrapyrrole (Corrin/Porphyrin) Methylases
336Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
325Fes/CIP4, and EFC/F-BAR homology domain
10616IQ calmodulin-binding motif
336Phosphoinositide 3-kinase family, accessory domain (PIK domain)
235Phospholipase D Active site motif
415Regulator of G protein signaling domain
448GTPase-activator protein for Ras-like GTPase
111627RasGEF domain
71017RasGEF N-terminal motif
12820RhoGAP domain
131225RhoGEF domain
213SPRY domain
336RNA polymerase Rpb1, domain 2
11Guanylate kinase
347Gelsolin repeat
10717UBA/TS-N domain
9817PHD-finger
112Filamin/ABP280 repeat
112GGL domain
121123HECT-domain (ubiquitin-transferase)
11Helix-hairpin-helix motif
11BRCA2 repeat
112MSP (Major sperm protein) domain
459Ribonuclease III domain
224Region in Clathrin and VPS
336RanBP1 domain
224PPIC-type PPIASE domain
246Zn-finger in Ran binding protein and others
91221Zinc finger C-x8-C-x5-C-x3-H type (and similar)
112B-box zinc finger
181533F-box domain
5510CRAL/TRIO domain
11BTB/POZ domain
112Inhibitor of Apoptosis domain
224Voltage gated chloride channel
112Caspase domain
11GDSL-like Lipase/Acylhydrolase
112Poly-adenylate binding protein, unique domain
11POLO box duplicated region
101020ABC transporter transmembrane region
1414Integrase core domain
538FAD binding domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
112HAMP domain
112ribosomal L5P family C-terminus
6511Insulinase (Peptidase family M16)
459Dehydrogenase E1 component
7512Elongation factor G C-terminus
112HMGL-like
336DnaJ central domain
224Ribosomal protein L1p/L10e family
6511Cation transporting ATPase, C-terminus
7613Cation transporter/ATPase, N-terminus
11dUTPase
112Aconitase C-terminal domain
112Acyl transferase domain
151631haloacid dehalogenase-like hydrolase
336Glycosyl hydrolases family 18
112Proliferating cell nuclear antigen, N-terminal domain
112Translation initiation factor IF-3, C-terminal domain
112Acylphosphatase
112Adenylosuccinate synthetase
112Asparaginase, N-terminal
336Peptidase S24-like
112Inorganic pyrophosphatase
112Glycosyl hydrolases family 16
2243-hydroxyacyl-CoA dehydrogenase, C-terminal domain
112HhH-GPD superfamily base excision DNA repair protein
224Asparagine synthase
538Septin
257tRNA synthetases class I (E and Q), catalytic domain
112tRNA synthetases class I (R)
549XPG N-terminal domain
448Metallo-beta-lactamase superfamily
437Choline/Carnitine o-acyltransferase
112Ferrochelatase
112Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
112Electron transfer flavoprotein FAD-binding domain
213RNB domain
224CNH domain
5611Dual specificity phosphatase, catalytic domain
112MyTH4 domain
336P21-Rho-binding domain
9918PX domain
224Ras association (RalGDS/AF-6) domain
123UBX domain
336VHS domain
224Phosphoinositide 3-kinase C2
112Carbon-nitrogen hydrolase
448Syntaxin
325Pumilio-family RNA binding repeat
5510Histone-like transcription factor (CBF/NF-Y) and archaeal histone
112Pterin binding enzyme
123ER lumen protein retaining receptor
112Glycoprotease family
437impB/mucB/samB family
112
112Ribosomal L15
112Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
11Ribosomal L29 protein
112Ribosomal L39 protein
112Ribosomal S17
112Ribulose-phosphate 3 epimerase family
336RNA pseudouridylate synthase
437Histone deacetylase domain
112Glycosyltransferase family 10 (fucosyltransferase) C-term
112POT family
13922SET domain
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
448XPG I-region
325DNA photolyase
112Nebulin repeat
112Nitroreductase family
112Cytosol aminopeptidase family, catalytic domain
112Ribosomal protein S16
235Acyl CoA binding protein
6713Cullin family
112Elongation factor TS
325FAD binding domain
112EamA-like transporter family
112
6612ThiF family
112Ribosomal family S4e
213Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
112T-box
213Sulfate permease family
112MATH domain
112Uncharacterized protein family UPF0004
112Transaldolase/Fructose-6-phosphate aldolase
448Mechanosensitive ion channel
459Adaptor complexes medium subunit family
224Exonuclease
112Dipeptidyl peptidase IV (DPP IV) N-terminal region
112Ribosomal protein L44
11DNA-dependent RNA polymerase
112Glycosyl transferase family 4
224Nucleosome assembly protein (NAP)
549Synaptobrevin
112Adenosine/AMP deaminase
325Oxidoreductase FAD-binding domain
224Glycosyltransferase family 20
112UDP-glucose/GDP-mannose dehydrogenase family, central domain
549PAS fold
437Sec1 family
224GDP dissociation inhibitor
8715Sodium/hydrogen exchanger family
235RNA polymerase Rpb3/RpoA insert domain
336Initiation factor 2 subunit family
213Electron transfer flavoprotein domain
112Ribosomal S3Ae family
11Ribosomal L27 protein
112GTP1/OBG
235Gamma-glutamyltranspeptidase
112GrpE
437TatD related DNase
112Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
336Dynamin central region
11Somatomedin B domain
1236-O-methylguanine DNA methyltransferase, DNA binding domain
246Carboxyl transferase domain
11UbiA prenyltransferase family
235Endoribonuclease L-PSP
11Vinculin family
112Cys/Met metabolism PLP-dependent enzyme
224Glycosyl hydrolases family 31
6612ABC-2 type transporter
224Amino-transferase class IV
213CDP-alcohol phosphatidyltransferase
336ATP dependent DNA ligase domain
112Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
112Glycosyl hydrolases family 38 N-terminal domain
112Presenilin
112Ribosomal protein S18
11Clathrin light chain
336Ubiquitin carboxyl-terminal hydrolase, family 1
123Ribosomal protein S19e
112Ribosomal protein S6e
6511Receptor family ligand binding region
336Transcription factor S-II (TFIIS)
112Surface antigen
224emp24/gp25L/p24 family/GOLD
112NifU-like domain
112Cyclin-dependent kinase regulatory subunit
112Asparaginase
112F-actin capping protein, beta subunit
224DNA mismatch repair protein, C-terminal domain
112Dephospho-CoA kinase
112G10 protein
112Succinate dehydrogenase/Fumarate reductase transmembrane subunit
11DNA topoisomerase
112Elongation factor P (EF-P) OB domain
112Enhancer of rudimentary
112Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
112RNA 3'-terminal phosphate cyclase
66123' exoribonuclease family, domain 1
112tRNA pseudouridine synthase D (TruD)
5510SPFH domain / Band 7 family
224Cytidylyltransferase family
235GDA1/CD39 (nucleoside phosphatase) family
5712Bacterial-like globin
112Hydroxymethylglutaryl-coenzyme A synthase N terminal
112Ribosomal protein L21e
112Ribosomal protein L36e
112Ribosomal protein L6e
112Phosphatidylethanolamine-binding protein
369RIO1 family
112Tub family
112Uncharacterized protein family UPF0016
112Putative RNA methylase family UPF0020
224PP-loop family
123Shwachman-Bodian-Diamond syndrome (SBDS) protein
112SNO glutamine amidotransferase family
224Translation initiation factor 1A / IF-1
54916S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
459RNA polymerase Rpb3/Rpb11 dimerisation domain
112RNA polymerases N / 8 kDa subunit
11Ribosomal protein L17
11Ribosomal protein L31e
112Ribosomal protein L34e
112Ribosomal protein S28e
224Ribosomal protein S8e
268Trehalase
11Uncharacterized protein family UPF0029
459Dihydrouridine synthase (Dus)
112Uroporphyrinogen decarboxylase (URO-D)
112NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
11Beta-eliminating lyase
11Adenylate cyclase associated (CAP) N terminal
224Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
4610Clathrin adaptor complex small chain
112Coproporphyrinogen III oxidase
224Dynein light chain type 1
224Formate/nitrite transporter
112GTP cyclohydrolase I
325HIT domain
112Indoleamine 2,3-dioxygenase
112Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
448Oxysterol-binding protein
112Phosphomannose isomerase type I
224Protein prenyltransferase alpha subunit repeat
1126-pyruvoyl tetrahydropterin synthase
112Pyridoxamine 5'-phosphate oxidase
112Ribosomal protein L19
224Ribosomal protein L24e
11Ribosomal protein L35Ae
5510Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
112Ribosomal protein S21e
112Ribosomal protein S7e
224Translation initiation factor SUI1
123Putative undecaprenyl diphosphate synthase
11Carbohydrate kinase
22Xylose isomerase-like TIM barrel
112Alanine dehydrogenase/PNT, C-terminal domain
224Aldose 1-epimerase
426Cytochrome c/c1 heme lyase
336FAD dependent oxidoreductase
11F-actin capping protein alpha subunit
112Fibrillarin
112Malate synthase
112Ribosomal protein L19e
112Ribosomal protein S24e
112Ribosomal protein S26e
11TEA/ATTS domain
112Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1127,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
112Phosphoenolpyruvate carboxykinase
112Ribosomal protein L13e
112Telomere recombination
437CAP-Gly domain
112
112Creatinase/Prolidase N-terminal domain
112DSBA-like thioredoxin domain
11Peroxidase, family 2
112Pterin 4 alpha carbinolamine dehydratase
112mRNA capping enzyme, catalytic domain
7714OB-fold nucleic acid binding domain
448Kelch motif
112Ribonuclease HII
549FYVE zinc finger
549Sec7 domain
7613NAD dependent epimerase/dehydratase family
112Porphobilinogen deaminase, dipyromethane cofactor binding domain
112SIS domain
112Helix-turn-helix
213ARID/BRIGHT DNA binding domain
112Clathrin propeller repeat
549JAB1/Mov34/MPN/PAD-1 ubiquitin protease
9918PCI domain
336tRNA synthetases class I (C) catalytic domain
213tRNA synthetases class II core domain (F)
112tRNA synthetases class II (A)
8513Putative GTPase activating protein for Arf
224tRNA pseudouridine synthase
224ENTH domain
325Reprolysin (M12B) family zinc metalloprotease
112NF-X1 type zinc finger
141428LSM domain
112R3H domain
112Amidase
112BAH domain
123AN1-like Zinc finger
224Peptidase family M3
336Peptidase family M1 domain
213Peptidase family M41
325Peptidase family M48
213Low molecular weight phosphotyrosine protein phosphatase
112MAGE family
224Eukaryotic porin
224GRIP domain
112Skp1 family, dimerisation domain
336Cytidylyltransferase-like
213PUA domain
112PLAT/LH2 domain
448S4 domain
11PWI domain
224Proprotein convertase P-domain
358IBR domain, a half RING-finger domain
6410Transmembrane amino acid transporter protein
112Frataxin-like domain
112V-type ATPase 116kDa subunit family
11Glycosyl transferase family 8
224Phosphatidylinositol-4-phosphate 5-Kinase
112Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
112ATP-NAD kinase
213Iron-sulphur cluster biosynthesis
131124Polysaccharide deacetylase
347DHHC palmitoyltransferase
336Glycosyl hydrolase family 47
437PPR repeat
224CorA-like Mg2+ transporter protein
224Cation efflux family
235Peptidase family M20/M25/M40
437Acyltransferase
549DnaJ C terminal domain
224Fumarylacetoacetate (FAA) hydrolase family
112FAD binding domain
123Natural resistance-associated macrophage protein
213PAP2 superfamily
224Aminomethyltransferase folate-binding domain
112MaoC like domain
11Myosin tail
123Adenylylsulphate kinase
5510G-patch domain
279Putative tRNA binding domain
112GAF domain
2136-phosphofructo-2-kinase
112NifU-like N terminal domain
123Flavin containing amine oxidoreductase
123Cyclin M transmembrane N-terminal domain
112Glycine cleavage H-protein
9716Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
224I/LWEQ domain
11Transposase DDE domain
2243'-5' exonuclease
112Flavin reductase like domain
112Proline dehydrogenase
336MutS domain I
112Peptide methionine sulfoxide reductase
112Hpt domain
224Choline/ethanolamine kinase
11SelR domain
112Methylmalonyl-CoA mutase
1124'-phosphopantetheinyl transferase superfamily
112Peptidase C13 family
224Eukaryotic initiation factor 4E
112Ribosomal protein L32
112Myo-inositol-1-phosphate synthase
224Type I phosphodiesterase / nucleotide pyrophosphatase
112Ribosomal protein S27
224Metalloenzyme superfamily
123Proteolipid membrane potential modulator
112SOR/SNZ family
112Riboflavin kinase
224Rhomboid family
336Sodium/calcium exchanger protein
224Queuine tRNA-ribosyltransferase
224UTP--glucose-1-phosphate uridylyltransferase
112Smr domain
224IPP transferase
112BolA-like protein
112Ham1 family
336FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
11Nucleoside transporter
448Patatin-like phospholipase
123Dienelactone hydrolase family
11STAS domain
11Large-conductance mechanosensitive channel, MscL
112Poly A polymerase head domain
112tRNA (Guanine-1)-methyltransferase
112ATP-sulfurylase
123Importin beta binding domain
11Toprim domain
4610MYND finger
336Acyl-CoA oxidase
101020Lipase (class 3)
11Ribosome recycling factor
11Reduced folate carrier
112Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
112Ribosomal L22e protein family
112Ribosomal L27e protein family
11Ribosomal L28e protein family
112Ribosomal L29e protein family
112Ribosomal L37ae protein family
112Ribosomal L38e protein family
112Ribosomal L32p protein family
112NIF3 (NGG1p interacting factor 3)
112Alternative oxidase
224Glycolipid 2-alpha-mannosyltransferase
112Ferric reductase like transmembrane component
112MraW methylase family
336snoRNA binding domain, fibrillarin
213Surp module
1125-formyltetrahydrofolate cyclo-ligase family
112ATP synthase subunit D
5510MAC/Perforin domain
112GPCR proteolysis site, GPS, motif
112IPT/TIG domain
112ACT domain
112HNH endonuclease
224FF domain
224NAC domain
224Proteasome/cyclosome repeat
112START domain
224MOZ/SAS family
11Retinoblastoma-associated protein B domain
11Retinoblastoma-associated protein A domain
325Putative diphthamide synthesis protein
112Domain of unknown function UPF0086
112AMMECR1
224Domain found in IF2B/IF5
112Memo-like protein
134RNase P subunit p30
112Iron-sulfur cluster assembly protein
11RNA 2'-phosphotransferase, Tpt1 / KptA family
112DNA primase small subunit
11Rpp14/Pop5 family
112Diphthamide synthase
112Ribosomal protein L37e
336Nucleotidyltransferase domain
112eIF-6 family
112Deoxyhypusine synthase
448Prefoldin subunit
112Cobalamin adenosyltransferase
13102350S ribosome-binding GTPase
112Ribosomal protein L14
11Protein of unknown function DUF89
123TRAM domain
5510DJ-1/PfpI family
224HD domain
123tRNA intron endonuclease, catalytic C-terminal domain
112Peptidyl-tRNA hydrolase PTH2
112Double-stranded DNA-binding domain
11VIT family
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
224Translin family
112TFIIE alpha subunit
11N2,N2-dimethylguanosine tRNA methyltransferase
112REJ domain
123BNR/Asp-box repeat
22Reeler domain
224eIF4-gamma/eIF5/eIF2-epsilon
325SCP-2 sterol transfer family
448SAP domain
112CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
11Cytochrome c oxidase subunit VIa
11MAS20 protein import receptor
112SURF4 family
112Palmitoyl protein thioesterase
11260Kd inner membrane protein
112Josephin
112DAD family
112Phosducin
112RHO protein GDP dissociation inhibitor
112Phosphatidylinositol transfer protein
11Aminopeptidase I zinc metalloprotease (M18)
224Fungalysin metallopeptidase (M36)
336
213Nuclear transport factor 2 (NTF2) domain
112Adenosine-deaminase (editase) domain
112Repair protein Rad1/Rec1/Rad17
213Rap/ran-GAP
213Sir2 family
224Zn-finger in ubiquitin-hydrolases and other protein
549Kinase associated domain 1
224RNA polymerases M/15 Kd subunit
112Dihydroneopterin aldolase
112Cytochrome C1 family
213PAZ domain
213Piwi domain
448AT hook motif
448Formin Homology 2 Domain
224HAT (Half-A-TPR) repeat
112Hr1 repeat
112ATP-dependent protease La (LON) substrate-binding domain
112PXA domain
112Regulatory subunit of type II PKA R-subunit
336STE like transcription factor
224SWIB/MDM2 domain
112Vacuolar sorting protein 9 (VPS9) domain
336WH2 motif
112Putative zinc finger in N-recognin (UBR box)
224Dynamin GTPase effector domain
11GYF domain
11ML domain
112Thymidylate kinase
224PA domain
112Transcriptional Coactivator p15 (PC4)
112Phospholipase/Carboxylesterase
112Biotin protein ligase C terminal domain
112Proteasome activator pa28 beta subunit
112TrkA-N domain
112RFX DNA-binding domain
112FAT domain
639FATC domain
224S1/P1 Nuclease
112Transcription initiation factor IIA, gamma subunit, helical domain
224Transcription initiation factor IID, 18kD subunit
112TFIIF, beta subunit HTH domain
112Ubiquinol-cytochrome C reductase complex 14kD subunit
112Cytochrome c oxidase subunit Va
112Transcription initiation factor IID, 31kD subunit
112
112Cytochrome oxidase c subunit VIb
224HORMA domain
112B12 binding domain
224E2F/DP family winged-helix DNA-binding domain
112Mitochondrial glycoprotein
224OTU-like cysteine protease
112Glycine cleavage system P-protein
213Trehalose-phosphatase
235Cell division protein 48 (CDC48), N-terminal domain
213Dolichyl-phosphate-mannose-protein mannosyltransferase
336JmjC domain, hydroxylase
112Anion-transporting ATPase
224jmjN domain
336SacI homology domain
112Putative methyltransferase
11Seryl-tRNA synthetase N-terminal domain
112Ribosomal silencing factor during starvation
325Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat
112Chromate transporter
112Flavoprotein
112Lecithin:cholesterol acyltransferase
112Patched family
8715RecF/RecN/SMC N terminal domain
336Tim17/Tim22/Tim23/Pmp24 family
336Fasciclin domain
123Met-10+ like-protein
235Core-2/I-Branching enzyme
213CobW/HypB/UreG, nucleotide-binding domain
538MORN repeat
112Oligosaccharyl transferase STT3 subunit
111021Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
336ZIP Zinc transporter
11CrcB-like protein, Camphor Resistance (CrcB)
112NAD synthase
112Maf-like protein
112Acetyl-CoA hydrolase/transferase N-terminal domain
112Acyl-CoA thioesterase
112D-Tyr-tRNA(Tyr) deacylase
437Uncharacterised ACR, YagE family COG1723
11GlcNAc-PI de-N-acetylase
112SOS response associated peptidase (SRAP)
112Uroporphyrinogen-III synthase HemD
112ATP-dependent Clp protease adaptor protein ClpS
112Cytochrome oxidase assembly protein
213CoA binding domain
112SCO1/SenC
213Phosphatidylserine decarboxylase
224Taurine catabolism dioxygenase TauD, TfdA family
112Paired amphipathic helix repeat
112Methyltransferase TYW3
112Pirin
112FtsX-like permease family
112CDC45-like protein
112SKIP/SNW domain
213ERCC4 domain
224Ku70/Ku80 beta-barrel domain
11Myosin N-terminal SH3-like domain
2243-hydroxyacyl-CoA dehydrogenase, NAD binding domain
112Proliferating cell nuclear antigen, C-terminal domain
112Quinolinate phosphoribosyl transferase, N-terminal domain
112Transcription initiation factor IIA, gamma subunit
112RPEL repeat
9918Acyl-CoA dehydrogenase, middle domain
5510Acyl-CoA dehydrogenase, N-terminal domain
112S-adenosylmethionine synthetase, central domain
112S-adenosylmethionine synthetase, C-terminal domain
112Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
112Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
235Iron/manganese superoxide dismutases, C-terminal domain
549Transketolase, pyrimidine binding domain
336Transketolase, C-terminal domain
112Glucose-6-phosphate dehydrogenase, C-terminal domain
112FGGY family of carbohydrate kinases, C-terminal domain
112Pyridoxal-dependent decarboxylase, pyridoxal binding domain
213Biotin carboxylase C-terminal domain
213Carbamoyl-phosphate synthase L chain, ATP binding domain
112Cytosol aminopeptidase family, N-terminal domain
11Cytochrome C oxidase subunit II, transmembrane domain
112Mago nashi protein
224Glutathione S-transferase, N-terminal domain
11Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
112Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
112Beta-ketoacyl synthase, C-terminal domain
437Thiolase, C-terminal domain
112Alpha amylase, C-terminal all-beta domain
224Ubiquitin interaction motif
112SEC-C motif
112Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
325MIR domain
213e3 binding domain
112ATP synthase, Delta/Epsilon chain, beta-sandwich domain
336TGS domain
112D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
112Prp18 domain
224CUE domain
224MA3 domain
437Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
549MIF4G domain
11Clp amino terminal domain, pathogenicity island component
336DDHD domain
213lactate/malate dehydrogenase, alpha/beta C-terminal domain
112Ribonucleotide reductase, barrel domain
437ATP synthase alpha/beta family, beta-barrel domain
336Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
325Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
112Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
11SRP54-type protein, helical bundle domain
112Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
538Adaptin C-terminal domain
246Pyruvate kinase, alpha/beta domain
448Sec63 Brl domain
224MIZ/SP-RING zinc finger
11BED zinc finger
437GRAM domain
549Prolyl oligopeptidase, N-terminal beta-propeller domain
112Catalytic LigB subunit of aromatic ring-opening dioxygenase
5712Ulp1 protease family, C-terminal catalytic domain
112Iron only hydrogenase large subunit, C-terminal domain
112Fumarate reductase flavoprotein C-term
112FAD linked oxidases, C-terminal domain
112Eukaryotic DNA topoisomerase I, DNA binding fragment
224Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
112THUMP domain
123Cell division protein 48 (CDC48), domain 2
448Tim10/DDP family zinc finger
112Mitosis protein DIM1
112TATA box binding protein associated factor (TAF)
213Tubulin binding cofactor A
112Signal peptide binding domain
112Cyclin, C-terminal domain
282452HEAT repeat
112Autophagy protein Atg8 ubiquitin like
224Prefoldin subunit
224Haemolysin-III related
224Glycerophosphoryl diester phosphodiesterase family
101020Dynein heavy chain region D6 P-loop domain
325Conserved hypothetical ATP binding protein
5510NLI interacting factor-like phosphatase
112Glycosyltransferase family 28 N-terminal domain
112Phosphatidyl serine synthase
224Thioesterase superfamily
437MBOAT, membrane-bound O-acyltransferase family
112GNT-I family
11TspO/MBR family
112Glutamate-cysteine ligase
235Exo70 exocyst complex subunit
224Sugar efflux transporter for intercellular exchange
112CutA1 divalent ion tolerance protein
213Phosphotyrosyl phosphate activator (PTPA) protein
112BRO1-like domain
336Biotin/lipoate A/B protein ligase family
325DNA polymerase family B, exonuclease domain
527SPX domain
5510ABC1 family
213BAR domain
11Herpesviridae UL52/UL70 DNA primase
112EXS family
112Plus-3 domain
549Anticodon binding domain
112PBS lyase HEAT-like repeat
347Tubulin-tyrosine ligase family
336TB2/DP1, HVA22 family
448Chitin synthase
6612Elongation factor Tu C-terminal domain
121022Elongation factor Tu domain 2
112Ferredoxin-fold anticodon binding domain
6612Triose-phosphate Transporter family
112Ubiquitin fusion degradation protein UFD1
11Transcription factor IIA, alpha/beta subunit
224ALG6, ALG8 glycosyltransferase family
224XRN 5'-3' exonuclease N-terminus
5510Tyrosine phosphatase family
224Uracil DNA glycosylase superfamily
2352OG-Fe(II) oxygenase superfamily
112Non-repetitive/WGA-negative nucleoporin C-terminal
325CPSF A subunit region
112Vacuolar (H+)-ATPase G subunit
33DDE superfamily endonuclease
112Protein of unknown function, DUF255
112LUC7 N_terminus
112Eukaryotic glutathione synthase
112Glycosyl hydrolase family 63 C-terminal domain
112TLC ATP/ADP transporter
112V-ATPase subunit C
112V-ATPase subunit H
11Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
112Cdc37 N terminal kinase binding
112Rer1 family
112Anaphase-promoting complex, subunit 10 (APC10)
112Roadblock/LC7 domain
112EB1-like C-terminal motif
112mRNA capping enzyme
112S25 ribosomal protein
112Transcription factor AP-2
11Methylmalonyl Co-A mutase-associated GTPase MeaB
112Cornichon protein
112HpcH/HpaI aldolase/citrate lyase family
11Lytic transglycolase
112Eukaryotic phosphomannomutase
224SART-1 family
112Oligosaccharyltransferase 48 kDa subunit beta
112Serine incorporator (Serinc)
112DOMON domain
7613Snf7
213YEATS family
224ZPR1 zinc-finger domain
11Dicer dimerisation domain
112PRP38 family
142034Endonuclease/Exonuclease/phosphatase family
112CAS/CSE protein, C-terminus
112LEM3 (ligand-effect modulator 3) family / CDC50 family
224Legume-like lectin family
112Regulator of Vps4 activity in the MVB pathway
437SAC3/GANP family
112Platelet-activating factor acetylhydrolase, isoform II
224Saccharopine dehydrogenase NADP binding domain
112Early transcription elongation factor of RNA pol II, NGN section
224FAD binding domain of DNA photolyase
224NAD binding domain of 6-phosphogluconate dehydrogenase
112dDENN domain
112uDENN domain
112PCRF domain
224eRF1 domain 1
224eRF1 domain 2
224eRF1 domain 3
112Smg-4/UPF3 family
112ATP cone domain
112Putative GTP-binding controlling metal-binding
112B3/4 domain
11tRNA synthetase B5 domain
112Arginyl tRNA synthetase N terminal domain
112Calcium-activated BK potassium channel alpha subunit
112Plectin/S10 domain
11Structure-specific recognition protein (SSRP1)
112Transcription initiation factor TFIID 23-30kDa subunit
112Na+/H+ antiporter family
112Cullin binding
112EMG1/NEP1 methyltransferase
112Citrate transporter
11