PFAM Domains • Cryptococcus neoformans var. grubii H99
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Annotations/GenomesCopci1Cryne_H99_1Cryne_JEC21_1Malgl1Pucgr1Ustma1TotalAnnotation Description
PFAMs
7,6785,7325,7904,0576,7845,65835,699
11137 transmembrane receptor (rhodopsin family)
433131303530200ATPase family associated with various cellular activities (AAA)
463433232538199ABC transporter
44445425ATP synthase alpha/beta family, nucleotide-binding domain
213EGF-like domain
15131314171385Elongation factor Tu GTP binding domain
1099771254Helix-loop-helix DNA-binding domain
74112Hsp20/alpha crystallin family
88989749Hsp70 protein
88878847KH domain
111115SH2 domain
312220152822138SH3 domain
121012991062Actin
931815131615170Ankyrin repeat
88878847ADP-ribosylation factor family
13881716971Eukaryotic aspartyl protease
33323317Cyclic nucleotide-binding domain
1111116Cytochrome c
62221215Double-stranded RNA binding motif
191616132117102EF hand
222222124Fe-4S binding domain
1111116Fibronectin type III domain
1113Globin
148628442Glutathione S-transferase, C-terminal domain
32211110Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
106518636Homeodomain
22Laminin EGF domain
22222212lactate/malate dehydrogenase, NAD binding domain
54465428Myosin head (motor domain)
1345561619185Cytochrome P450
13689968211288603Protein kinase domain
171110781366Pyridine nucleotide-disulphide oxidoreductase
322325142524143Ras family
81010491152Response regulator receiver domain
211119630RNase H
646265418556373RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
12728Retroviral aspartyl protease
1811222Reverse transcriptase (RNA-dependent DNA polymerase)
1111518Copper/zinc superoxide dismutase (SODC)
2112129Iron/manganese superoxide dismutases, alpha-hairpin domain
1233314439Subtilase family
20625781621184Sugar (and other) transporter
9810781052Thioredoxin
54445426Tubulin/FtsZ family, GTPase domain
32117von Willebrand factor type A domain
602426155228205Zinc finger, C2H2 type
4832362111035282Zinc finger, C3HC4 type (RING finger)
211110514211200Zinc knuckle
22222212Protein-tyrosine phosphatase
493534122942201short chain dehydrogenase
292528171123133Zinc-binding dehydrogenase
43334623Thiolase, N-terminal domain
21112512Beta-ketoacyl synthase, N-terminal domain
335424212Fe-2S iron-sulfur cluster binding domain
12321110Enolase, C-terminal TIM barrel domain
11Cytochrome C and Quinol oxidase polypeptide I
87767641Glutamine amidotransferase class-I
1010109121061TCP-1/cpn60 chaperonin family
42213214Glutamine synthetase, catalytic domain
1112128Triosephosphate isomerase
1110109101363E1-E2 ATPase
1688824771Core histone H2A/H2B/H3/H4
11Copper binding proteins, plastocyanin/azurin family
89114335Alpha amylase, catalytic domain
63315422Phorbol esters/diacylglycerol binding domain (C1 domain)
59948439Bacterial transferase hexapeptide (six repeats)
33335320tRNA synthetases class I (I, L, M and V)
1299610854Cyclin, N-terminal domain
194516944Carboxylesterase family
44446426DNA polymerase family B
35223116ATP synthase subunit C
123Legume lectin domain
42222315Peroxidase
235Beta-lactamase
426C-5 cytosine-specific DNA methylase
311920161721124Calcineurin-like phosphoesterase
115549539Cellulase (glycosyl hydrolase family 5)
56664633tRNA synthetases class II (D, K and N)
363434303436204Mitochondrial carrier protein
16161510151385Aminotransferase class I and II
67768741Phosphoribosyl transferase domain
141313814971Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
1121117Phosphoglycerate kinase
22222212Ribosomal protein S4/S9 N-terminal domain
22223213Ribosomal protein S12/S23
111115Chaperonin 10 Kd subunit
17121277964C2 domain
19161613181698PH domain
67945435bZIP transcription factor
1214146121674Aldehyde dehydrogenase family
42777752483308Fungal Zn(2)-Cys(6) binuclear cluster domain
241920101918110Cytochrome b5-like Heme/Steroid binding domain
224Oxidoreductase molybdopterin binding domain
107766743Oxidoreductase NAD-binding domain
262121155817158SNF2 family N-terminal domain
22122211Ribosomal protein S7p/S5e
231919111716105Ubiquitin-conjugating enzyme
57852734Isocitrate/isopropylmalate dehydrogenase
22222111Ribosomal Proteins L2, RNA binding domain
222118Hsp90 protein
22222111Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
1111116Dihydrofolate reductase
2217214Cysteine-rich secretory protein family
1111217Ribosomal protein S3, C-terminal domain
112Cupin
31217Annexin
333233172-oxoacid dehydrogenases acyltransferase (catalytic domain)
4452621Catalase
122218Disintegrin
11UDP-glucoronosyl and UDP-glucosyl transferase
589411542Aminotransferase class-III
2222210Ribosomal protein S19
1111217DNA gyrase B
42251216Thiamine pyrophosphate enzyme, central domain
33333318Lyase
22211210Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
1111116Adenylate and Guanylate cyclase catalytic domain
1111116ATP synthase delta (OSCP) subunit
1111116Orotidine 5'-phosphate decarboxylase / HUMPS family
2111117Indole-3-glycerol phosphate synthase
2226Aromatic amino acid lyase
1121117Pyruvate kinase, barrel domain
810109131060Kinesin motor domain
322326203226159DnaJ domain
14141414151485Proteasome subunit
211110621Major intrinsic protein
1111116ATP synthase
22Glycosyl hydrolase family 1
111143'5'-cyclic nucleotide phosphodiesterase
1111116Profilin
1112128Ribosomal protein L22p/L17e
22222212Ribosomal protein L14p/L23e
171214891171Ubiquitin family
55633325Cofilin/tropomyosin-type actin-binding protein
211121814-3-3 protein
2113411Alkaline phosphatase
11114Zinc carboxypeptidase
22211910121397Aldo/keto reductase family
1378871255Myb-like DNA-binding domain
56532526Forkhead domain
11226Glycosyl hydrolases family 32 N-terminal domain
1111116Ribosomal protein L16p/L10e
22212110Ribosomal protein S14p/S29e
33333318FKBP-type peptidyl-prolyl cis-trans isomerase
1221118Glutathione peroxidase
2112129
65535428Flavodoxin
111115Calreticulin family
19120Common central domain of tyrosinase
75636734Aminotransferase class-V
2221119Ribonucleotide reductase, small chain
514140366940277DEAD/DEAH box helicase
9271726015867520Helicase conserved C-terminal domain
111317EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
2221119Ribosomal protein L23
1111116Pyridoxal-dependent decarboxylase, C-terminal sheet domain
1221118Ribosomal protein L5
53432522Pyridoxal-dependent decarboxylase conserved domain
51112111Citrate synthase, C-terminal domain
45756532GHMP kinases N terminal domain
66545531Biotin carboxylase, N-terminal domain
1111217Tryptophan synthase alpha chain
789581047Pyridoxal-phosphate dependent enzyme
179107101265NUDIX domain
46545428pfkB family carbohydrate kinase
311117Glycosyl hydrolases family 28
22222212Ribosomal protein L3
22221110Ribosomal protein L11, RNA binding domain
7996131054Histidine phosphatase superfamily (branch 1)
1111116Thymidylate synthase
44445425ATP synthase alpha/beta chain, C terminal domain
43425523Calponin homology (CH) domain
44447528Glutamine amidotransferases class-II
22222212Ribosomal protein S15
33'Cold-shock' DNA-binding domain
522716Thaumatin family
1111116Fructose-1-6-bisphosphatase, N-terminal domain
1111116Ribonucleotide reductase, all-alpha domain
22223314Ribosomal protein S2
12222211SRF-type transcription factor (DNA-binding and dimerisation domain)
111210871058GATA zinc finger
1316148201687Amino acid permease
11Bacterial regulatory proteins, crp family
54524323Prolyl oligopeptidase family
1111127Ribosomal protein L30p/L7e
55665936Histidine phosphatase superfamily (branch 2)
1111116Respiratory-chain NADH dehydrogenase, 30 Kd subunit
45554427Aconitase family (aconitate hydratase)
65213Glycosyl hydrolase family 10
311128Glycosyl hydrolases family 17
22222212Ribosomal protein S5, N-terminal domain
22221312Nucleoside diphosphate kinase
3115Tetraspanin family
22Galactoside-binding lectin
2221119Ribosomal protein S10p/S20e
322119Arrestin (or S-antigen), N-terminal domain
211116Phosphoglucose isomerase
1113Carbohydrate phosphorylase
1111116SecY translocase
111115Respiratory-chain NADH dehydrogenase, 49 Kd subunit
22223213Ribosomal protein L6
43334320Polyprenyl synthetase
22214213Hexokinase
43336221Dynamin family
1111116Transcription factor TFIID (or TATA-binding protein, TBP)
43323419Rieske [2Fe-2S] domain
1113Phytochrome region
98747944Biotin-requiring enzyme
1111116Phosphofructokinase
22222212Ribosomal protein S17
1111116Hydroxymethylglutaryl-coenzyme A reductase
3343215FGGY family of carbohydrate kinases, N-terminal domain
755581141Enoyl-CoA hydratase/isomerase
22222212Ribosomal protein S9/S16
32323215Transcription factor TFIIB repeat
5101055742Cytidine and deoxycytidylate deaminase zinc-binding region
1111116Molybdopterin oxidoreductase
78838337Chromo (CHRromatin Organisation MOdifier) domain
3111118Phosphatidylinositol-specific phospholipase C, Y domain
32112110Phosphatidylinositol-specific phospholipase C, X domain
691031635D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
2331110Malic enzyme, N-terminal domain
11111166-phosphogluconate dehydrogenase, C-terminal domain
1755612651Multicopper oxidase
1271336849WW domain
2112118Ribosomal RNA adenine dimethylase
12410210491106100627WD domain, G-beta repeat
2111218Heavy-metal-associated domain
33334319Adenylate kinase
2112219Phosphoglucomutase/phosphomannomutase, C-terminal domain
21122210Ribosomal protein S8
21122210Ribosomal protein S11
54446528LIM domain
3111129Regulator of chromosome condensation (RCC1) repeat
22222212Ribosomal protein S13/S18
22224214chorismate binding enzyme
3333231760s Acidic ribosomal protein
44439428Prenyltransferase and squalene oxidase repeat
74438430Protein kinase C terminal domain
111115Single-strand binding protein family
1111217S-adenosylmethionine synthetase, N-terminal domain
1110101081059Bromodomain
9784101149Acyl-CoA dehydrogenase, C-terminal domain
15141512141383Ubiquitin carboxyl-terminal hydrolase
11114Ribosomal protein L36
1124Ribonuclease T2 family
34426423HSF-type DNA-binding
22222212SRP54-type protein, GTPase domain
1111217Urease alpha-subunit, N-terminal domain
577512642Serine carboxypeptidase
88878645Phosphatidylinositol 3- and 4-kinase
25511115Transketolase, thiamine diphosphate binding domain
617Glycosyl hydrolases family 11
1124WHEP-TRS domain
23322214Inositol monophosphatase family
44634425Glutaredoxin
31132313Isocitrate lyase family
1111217Serine hydroxymethyltransferase
211127Iron-containing alcohol dehydrogenase
12222312Ribosomal protein L10
4443318KOW motif
111115Ribosomal protein L34
1113Ribosomal protein L33
33221213RF-1 domain
11147Sodium:solute symporter family
1111116Imidazoleglycerol-phosphate dehydratase
1111116DNA polymerase family A
1111116IMP dehydrogenase / GMP reductase domain
1111116Glucose-6-phosphate dehydrogenase, NAD binding domain
85556534Protein phosphatase 2C
12213110Nucleotidyl transferase
72212115Carbonic anhydrase
112116Phosphoribulokinase / Uridine kinase family
84438431Fatty acid desaturase
66645633MutS domain V
1111116Delta-aminolevulinic acid dehydratase
23211211Arginase family
66677638MCM P-loop domain
1121229Squalene/phytoene synthase
87734534FHA domain
30910121229102AMP-binding enzyme
163314431G-protein alpha subunit
2677311862HMG (high mobility group) box
47724630His Kinase A (phospho-acceptor) domain
22222313Armadillo/beta-catenin-like repeat
292223202723144Tetratricopeptide repeat
33322316Ion transport protein
2111218DNA gyrase/topoisomerase IV, subunit A
107676440BRCA1 C Terminus (BRCT) domain
67736534Glycosyl transferases group 1
42223316Glycosyl transferase family 2
3115SAM domain (Sterile alpha motif)
4222111linker histone H1 and H5 family
111115Ribosomal protein L7/L12 C-terminal domain
1214Pectate lyase
1113ribonuclease
1111217Urease, gamma subunit
33324520CoA-ligase
623541131Phosphopantetheine attachment site
23322416Formyl transferase
9101077649Metallopeptidase family M24
15171913151594Leucine Rich Repeat
34910132022108alpha/beta hydrolase fold
33333318RNA polymerase Rpb2, domain 6
53414219PB1 domain
22212211Staphylococcal nuclease homologue
991076849Rab-GTPase-TBC domain
111115Tudor domain
1111217WH1 domain
43414218Zinc finger, ZZ type
22116HRDC domain
117767745CBS domain
22222212Ribosomal protein L13
22222212Ribosomal protein L4/L1 family
111115Clp protease
63445426S1 RNA binding domain
111115HIUase/Transthyretin family
43322317AhpC/TSA family
43344422tRNA synthetases class I (W and Y)
1111127UvrD/REP helicase N-terminal domain
44434322Rhodanese-like domain
22321313Universal stress protein family
2818139111897Acetyltransferase (GNAT) family
111115SecE/Sec61-gamma subunits of protein translocation complex
1111116C-terminal regulatory domain of Threonine dehydratase
22222212AIR synthase related protein, N-terminal domain
76698945tRNA synthetase class II core domain (G, H, P, S and T)
112Phage integrase family
22211210Tetrapyrrole (Corrin/Porphyrin) Methylases
1111116Glycosyl transferase family, a/b domain
221229Class II Aldolase and Adducin N-terminal domain
11Influenza non-structural protein (NS1)
22Adenoviral fibre protein (repeat/shaft region)
21213110Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
55517326Fes/CIP4, and EFC/F-BAR homology domain
47642326IQ calmodulin-binding motif
22222212Phosphoinositide 3-kinase family, accessory domain (PIK domain)
34524321Phospholipase D Active site motif
111115Regulator of G protein signaling domain
43225420GTPase-activator protein for Ras-like GTPase
103334528RasGEF domain
93244527RasGEF N-terminal motif
129119131064RhoGAP domain
14141210141074RhoGEF domain
43323217SPRY domain
33333318RNA polymerase Rpb1, domain 2
1111116Guanylate kinase
43433320Gelsolin repeat
1181068750UBA/TS-N domain
18152012121592PHD-finger
2215GGL domain
54457530HECT-domain (ubiquitin-transferase)
22211210Helix-hairpin-helix motif
11BRCA2 repeat
3111118MSP (Major sperm protein) domain
65516225Ribonuclease III domain
22211210Region in Clathrin and VPS
33333318RanBP1 domain
2111218PPIC-type PPIASE domain
4127Zn-finger in Ran binding protein and others
2219171091592Zinc finger C-x8-C-x5-C-x3-H type (and similar)
11B-box zinc finger
55Poly(ADP-ribose) polymerase catalytic domain
211116Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
197201872617285F-box domain
1111116Elongation factor 1 gamma, conserved domain
91111Calpain family cysteine protease
211116Copper fist DNA binding domain
75469839CRAL/TRIO domain
19512431BTB/POZ domain
1755128Ricin-type beta-trefoil lectin domain
111115Inhibitor of Apoptosis domain
32214214Voltage gated chloride channel
152211122Caspase domain
10331320GDSL-like Lipase/Acylhydrolase
1111116Poly-adenylate binding protein, unique domain
111115POLO box duplicated region
23151414111895ABC transporter transmembrane region
31131633Integrase core domain
33333318FAD binding domain
2248Condensation domain
1111116S-adenosyl-L-homocysteine hydrolase, NAD binding domain
2111218HAMP domain
2221119ribosomal L5P family C-terminus
55554529Insulinase (Peptidase family M16)
43323318Dehydrogenase E1 component
1111116Lumazine binding domain
75556533Elongation factor G C-terminus
44435424HMGL-like
44643425DnaJ central domain
33Starch binding domain
22221211Ribosomal protein L1p/L10e family
64444729Cation transporting ATPase, C-terminus
86648840Cation transporter/ATPase, N-terminus
122117dUTPase
45544426Aconitase C-terminal domain
43424320Amino acid kinase family
2111117N-(5'phosphoribosyl)anthranilate (PRA) isomerase
31122514Acyl transferase domain
1111217Urease beta subunit
244111Dihydrodipicolinate synthetase family
242624152325137haloacid dehalogenase-like hydrolase
156Glycosyl hydrolases family 2
933117235Glycosyl hydrolases family 18
1111116Proliferating cell nuclear antigen, N-terminal domain
112Acylphosphatase
1111116Adenylosuccinate synthetase
111115Asparaginase, N-terminal
1233211Peptidase S24-like
1111116Inorganic pyrophosphatase
61111919Glycosyl hydrolases family 16
4223112Glycosyl hydrolases family 15
65533224NADH:flavin oxidoreductase / NADH oxidase family
123122113-hydroxyacyl-CoA dehydrogenase, C-terminal domain
211228Glycosyl hydrolase family 20, catalytic domain
43334522HhH-GPD superfamily base excision DNA repair protein
1111116AIR carboxylase
342369963GMC oxidoreductase
22222212Asparagine synthase
4444Fungal cellulose binding domain
754413336Septin
1111116EF-1 guanine nucleotide exchange domain
1111217Homoserine dehydrogenase
2226Flavin-binding monooxygenase-like
11LPXTG cell wall anchor motif
33333318tRNA synthetases class I (E and Q), catalytic domain
1111116tRNA synthetases class I (R)
56624629XPG N-terminal domain
107545738Metallo-beta-lactamase superfamily
43325320Choline/Carnitine o-acyltransferase
111115Putative esterase
11114Glycosyl hydrolase family 9
1111116Ferrochelatase
2222210Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
1111217Arginosuccinate synthase
1111116Electron transfer flavoprotein FAD-binding domain
33333318RNB domain
2338Dioxygenase
43234218CNH domain
22222212Diacylglycerol kinase catalytic domain
126536739Dual specificity phosphatase, catalytic domain
1113MyTH4 domain
44324421P21-Rho-binding domain
1412127141271PX domain
32132314Ras association (RalGDS/AF-6) domain
42233317UBX domain
44424523VHS domain
1111116Phosphoinositide 3-kinase C2
22236217DAHP synthetase I family
36646631Carbon-nitrogen hydrolase
2114N-acetyltransferase
1111116Prephenate dehydratase
53334422Syntaxin
64374428Pumilio-family RNA binding repeat
65555733Histone-like transcription factor (CBF/NF-Y) and archaeal histone
1111217Pterin binding enzyme
1111116ER lumen protein retaining receptor
22223213Glycoprotease family
1111116Histidinol dehydrogenase
33324419impB/mucB/samB family
1111116
1111116Ribosomal L15
1111116Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal prokaryotic L21 protein
11114Ribosomal L28 family
1111116Ribosomal L29 protein
111115Ribosomal L39 protein
1111217Ribosomal S17
1111116Ribulose-phosphate 3 epimerase family
1111116Translationally controlled tumour protein
6814Glycosyl hydrolase family 7
2111218RNA pseudouridylate synthase
67756637Histone deacetylase domain
2111117POT family
21213211PWWP domain
181210617871SET domain
53312115Isochorismatase family
211138Permease family
111115Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
93444529XPG I-region
11114Acetokinase family
1539DNA photolyase
11Cation-independent mannose-6-phosphate receptor repeat
21115Nitroreductase family
11114Cytosol aminopeptidase family, catalytic domain
2125Sulfatase
11111166,7-dimethyl-8-ribityllumazine synthase
1111116Ribosomal protein S16
33322215Acyl CoA binding protein
64545428Cullin family
111115Elongation factor TS
32214315FAD binding domain
2619O-methyltransferase domain
65514324EamA-like transporter family
21114211
777710846ThiF family
1111116Ribosomal family S4e
3111129Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
42212213Ammonium Transporter Family
33433218Sulfate permease family
2111319MATH domain
22211210Dehydratase family
32211312Transaldolase/Fructose-6-phosphate aldolase
3114312Mechanosensitive ion channel
1111217GTP cyclohydrolase II
11112173,4-dihydroxy-2-butanone 4-phosphate synthase
43344422Adaptor complexes medium subunit family
87747538Exonuclease
111115Dipeptidyl peptidase IV (DPP IV) N-terminal region
77312323Glycosyl hydrolase family 3 N terminal domain
111115Ribosomal protein L44
1121218DNA-dependent RNA polymerase
11FAD binding domain in molybdopterin dehydrogenase
1111116Glycosyl transferase family 4
1121117HCO3- transporter family
22321212Nucleosome assembly protein (NAP)
45426425Synaptobrevin
1111116GMP synthase C terminal domain
66Phage lysozyme
31112311Adenosine/AMP deaminase
44533322Oxidoreductase FAD-binding domain
123Thioesterase domain
22213111Histidine biosynthesis protein
32332316Glycosyltransferase family 20
1111116UDP-glucose/GDP-mannose dehydrogenase family, central domain
22222111Carbamoyl-phosphate synthase small chain, CPSase domain
22217PAS fold
2111128Probable molybdopterin binding domain
44444424Sec1 family
22222212GDP dissociation inhibitor
74436731Sodium/hydrogen exchanger family
22222212RNA polymerase Rpb3/RpoA insert domain
44539328Initiation factor 2 subunit family
22217PQQ enzyme repeat
22222212Electron transfer flavoprotein domain
111115Uricase
1111318Ribosomal S3Ae family
111115Ribosomal L27 protein
111115GTP1/OBG
23312314Gamma-glutamyltranspeptidase
1111116Ribosomal L40e family
1111116GrpE
32222213TatD related DNase
2111117Inhibitor of apoptosis-promoting Bax1
1111116Eukaryotic DNA topoisomerase I, catalytic core
32225115Dynamin central region
21146-O-methylguanine DNA methyltransferase, DNA binding domain
11136Bacteriorhodopsin-like protein
32212414Carboxyl transferase domain
52226219UbiA prenyltransferase family
89612228Endoribonuclease L-PSP
112Phosphorylase superfamily
1113Mannose-6-phosphate isomerase
53454425Cys/Met metabolism PLP-dependent enzyme
33322316Glycosyl hydrolases family 31
1111116NADH ubiquinone oxidoreductase, 20 Kd subunit
710826841ABC-2 type transporter
22211311Amino-transferase class IV
44446325CDP-alcohol phosphatidyltransferase
55533425ATP dependent DNA ligase domain
36631322FMN-dependent dehydrogenase
1111116Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
31112193-beta hydroxysteroid dehydrogenase/isomerase family
111126Glycosyl hydrolases family 38 N-terminal domain
211127Nitrite and sulphite reductase 4Fe-4S domain
69419Cutinase
1111