PFAM Domains • Helobdella robusta
Annotations/GenomesCapca1Helro1Lotgi1TotalAnnotation Description
7581452451,1487 transmembrane receptor (rhodopsin family)
311647947 transmembrane receptor (Secretin family)
48616707 transmembrane sweet-taste receptor of 3 GCPR
393836113ATPase family associated with various cellular activities (AAA)
844444172ABC transporter
65415ATP synthase alpha/beta family, nucleotide-binding domain
11Cystine-knot domain
216109145470EGF-like domain
21151753Elongation factor Tu GTP binding domain
836882233Helix-loop-helix DNA-binding domain
1641030Hsp20/alpha crystallin family
1791238Hsp70 protein
21411880KH domain
3572769Kunitz/Bovine pancreatic trypsin inhibitor domain
112Methyl-accepting chemotaxis protein (MCP) signalling domain
395726122SH2 domain
9610979284SH3 domain
1481032Transforming growth factor beta like domain
911929TNFR/NGFR cysteine-rich region
430161191782Ankyrin repeat
106110121337PAN domain
17172054ADP-ribosylation factor family
2237Eukaryotic aspartyl protease
353940114Cyclic nucleotide-binding domain
637868209Cadherin domain
27211Cystatin domain
1113Cytochrome c
14151241Double-stranded RNA binding motif
184148200532EF hand
1022144Fe-4S binding domain
211518Intermediate filament protein
1178570272Fibronectin type III domain
30102060Glutathione S-transferase, C-terminal domain
3216Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
127140154421Immunoglobulin domain
134Insulin/IGF/Relaxin family
11162148Kazal-type serine protease inhibitor domain
46102076Kringle domain
73515Laminin B (Domain IV)
25292377Laminin EGF domain
22151956Laminin G domain
76518Laminin N-terminal (Domain VI)
36211lactate/malate dehydrogenase, NAD binding domain
1055859222Low-density lipoprotein receptor domain class A
27102057Low-density lipoprotein receptor repeat class B
194101124419Lectin C-type domain
36154192Ligand-gated ion channel
421218Lipocalin / cytosolic fatty-acid binding protein family
11C-type lysozyme/alpha-lactalbumin family
18182864Myosin head (motor domain)
2226LNR domain
914068199Cytochrome P450
11Phospholipase A2
3184272981,043Protein kinase domain
1461030Pyridine nucleotide-disulphide oxidoreductase
917188250Ras family
66Response regulator receiver domain
224127RNase H
139194124457RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
3238Retroviral aspartyl protease
416525Serpin (serine protease inhibitor)
631019Copper/zinc superoxide dismutase (SODC)
3216Iron/manganese superoxide dismutases, alpha-hairpin domain
1914841Subtilase family
432456123Sugar (and other) transporter
7712149238Sushi repeat (SCR repeat)
34310Thyroglobulin type-1 repeat
11Snake toxin and toxin-like protein
6511Trefoil (P-type) domain
782358159Thrombospondin type 1 domain
331390136Tubulin/FtsZ family, GTPase domain
802964173von Willebrand factor type A domain
951428von Willebrand factor type C domain
44111166von Willebrand factor type D domain
1121629WAP-type (Whey Acidic Protein) 'four-disulfide core'
4443123791,135Zinc finger, C2H2 type
124202175501Zinc finger, C3HC4 type (RING finger)
109101103313Zinc knuckle
437Zona pellucida-like domain
854345173Protein-tyrosine phosphatase
29252983Ligand-binding domain of nuclear hormone receptor
375033120Zinc finger, C4 type (two domains)
1193971229short chain dehydrogenase
3382162Zinc-binding dehydrogenase
95721Thiolase, N-terminal domain
82919Beta-ketoacyl synthase, N-terminal domain
12161139wnt family
10610262Fe-2S iron-sulfur cluster binding domain
15122249Papain family cysteine protease
3317Enolase, C-terminal TIM barrel domain
22Cytochrome C and Quinol oxidase polypeptide I
22Cytochrome C oxidase subunit II, periplasmic domain
63413Glutamine amidotransferase class-I
13101235TCP-1/cpn60 chaperonin family
213ATP synthase A chain
98219Glutamine synthetase, catalytic domain
1113Triosephosphate isomerase
1129848E1-E2 ATPase
874290219Core histone H2A/H2B/H3/H4
88Bacterial regulatory helix-turn-helix protein, lysR family
144927Alpha amylase, catalytic domain
23231965Phorbol esters/diacylglycerol binding domain (C1 domain)
1251027Bacterial transferase hexapeptide (six repeats)
97925tRNA synthetases class I (I, L, M and V)
19171854Cyclin, N-terminal domain
4071966Carboxylesterase family
54413DNA polymerase family B
46313ATP synthase subunit C
3339C-5 cytosine-specific DNA methylase
112NADH dehydrogenase
989549242Fibrinogen beta and gamma chains, C-terminal globular domain
403135106Calcineurin-like phosphoesterase
213Cellulase (glycosyl hydrolase family 5)
65516tRNA synthetases class II (D, K and N)
433336112Mitochondrial carrier protein
17111644Aminotransferase class I and II
97622Phosphoribosyl transferase domain
512421Pou domain - N-terminal to homeobox domain
2114Pancreatic hormone peptide
14171849Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
2215Phosphoglycerate kinase
1113Ribosomal protein S4/S9 N-terminal domain
2327Ribosomal protein S12/S23
44Bacterial regulatory helix-turn-helix proteins, AraC family
1113Chaperonin 10 Kd subunit
11Fibroblast growth factor
717770218C2 domain
928682260PH domain
15151848bZIP transcription factor
24121652Aldehyde dehydrogenase family
20121446Cytochrome b5-like Heme/Steroid binding domain
1113Oxidoreductase molybdopterin binding domain
136827Oxidoreductase NAD-binding domain
23232268SNF2 family N-terminal domain
2226Ribosomal protein S7p/S5e
352938102Ubiquitin-conjugating enzyme
64515Isocitrate/isopropylmalate dehydrogenase
2226Ribosomal Proteins L2, RNA binding domain
3339Hsp90 protein
1113Neurohypophysial hormones, C-terminal Domain
4127Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
2125Dihydrofolate reductase
18191754Cysteine-rich secretory protein family
1113Ribosomal protein S3, C-terminal domain
12171645Eukaryotic-type carbonic anhydrase
743142-oxoacid dehydrogenases acyltransferase (catalytic domain)
264737UDP-glucoronosyl and UDP-glucosyl transferase
114520Aminotransferase class-III
1113Ribosomal protein S19
1124DNA gyrase B
5139Thiamine pyrophosphate enzyme, central domain
361019Alpha-2-macroglobulin family
3216Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
461837101Sodium:neurotransmitter symporter family
44513Ferritin-like domain
794243164Adenylate and Guanylate cyclase catalytic domain
1113ATP synthase delta (OSCP) subunit
1113Orotidine 5'-phosphate decarboxylase / HUMPS family
11Bacterial DNA-binding protein
358ATP:guanido phosphotransferase, C-terminal catalytic domain
11Indole-3-glycerol phosphate synthase
2125Insulin-like growth factor binding protein
1113Neurohypophysial hormones, N-terminal Domain
4318Aromatic amino acid lyase
2327Pyruvate kinase, barrel domain
442640110Kinesin motor domain
384338119DnaJ domain
17151446Proteasome subunit
22Bowman-Birk serine protease inhibitor family
112TNF(Tumour Necrosis Factor) family
22141248Major intrinsic protein
1113ATP synthase
5712Glycosyl hydrolase family 1
111614413'5'-cyclic nucleotide phosphodiesterase
2215Ribosomal protein L22p/L17e
3227Ribosomal protein L14p/L23e
38193188Ubiquitin family
66517Cofilin/tropomyosin-type actin-binding protein
11Nerve growth factor family
1841314-3-3 protein
72211Alkaline phosphatase
27181257Zinc carboxypeptidase
1872146Aldo/keto reductase family
23181960Myb-like DNA-binding domain
38282995Forkhead domain
1113Ribosomal protein L16p/L10e
2114Ribosomal protein S14p/S29e
12111336FKBP-type peptidyl-prolyl cis-trans isomerase
3249Glutathione peroxidase
112Protamine P1
3328Calreticulin family
11Bacterial type II and III secretion system protein
3137Common central domain of tyrosinase
213Thymidine kinase
4239Aminotransferase class-V
1113Ribonucleotide reductase, small chain
636457184DEAD/DEAH box helicase
959082267Helicase conserved C-terminal domain
1315Fructose-bisphosphate aldolase class-I
1113Ribosomal protein L23
5128Pyridoxal-dependent decarboxylase, C-terminal sheet domain
1315Potato inhibitor I family
2114Ribosomal protein L5
1071027Pyridoxal-dependent decarboxylase conserved domain
1113Citrate synthase, C-terminal domain
34310Sodium / potassium ATPase beta chain
74516GHMP kinases N terminal domain
105621Biotin carboxylase, N-terminal domain
1751032Pyridoxal-phosphate dependent enzyme
510722'Paired box' domain
26181963NUDIX domain
43613pfkB family carbohydrate kinase
11Luciferase-like monooxygenase
2327Ribosomal protein L3
1214Ribosomal protein L11, RNA binding domain
86519Histidine phosphatase superfamily (branch 1)
1113Thymidylate synthase
45413ATP synthase alpha/beta chain, C terminal domain
334833114Calponin homology (CH) domain
53311Glutamine amidotransferases class-II
2226Ribosomal protein S15
218332'Cold-shock' DNA-binding domain
2215Fructose-1-6-bisphosphatase, N-terminal domain
1315Ribonucleotide reductase, all-alpha domain
3238Ribosomal protein S2
46313SRF-type transcription factor (DNA-binding and dimerisation domain)
914427GATA zinc finger
26212875Amino acid permease
11Bacterial regulatory proteins, crp family
45514Prolyl oligopeptidase family
1214Ribosomal protein L30p/L7e
107522Histidine phosphatase superfamily (branch 2)
2114Respiratory-chain NADH dehydrogenase, 30 Kd subunit
3227Aconitase family (aconitate hydratase)
231336Glycosyl hydrolase family 10
2226Ribosomal protein S5, N-terminal domain
75618Nucleoside diphosphate kinase
444137122Tetraspanin family
426Galactoside-binding lectin
2114Ribosomal protein S10p/S20e
1771640Arrestin (or S-antigen), N-terminal domain
2114PDGF/VEGF domain
2114Phosphoglucose isomerase
1214Carbohydrate phosphorylase
2114SecY translocase
1113Respiratory-chain NADH dehydrogenase, 49 Kd subunit
2215Ribosomal protein L6
43310Polyprenyl synthetase
55313Dynamin family
43411Biopterin-dependent aromatic amino acid hydroxylase
2215Transcription factor TFIID (or TATA-binding protein, TBP)
1212RTX calcium-binding nonapeptide repeat (4 copies)
213Pentaxin family
83617Rieske [2Fe-2S] domain
1326Integrin alpha cytoplasmic region
11phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
224Proton-conducting membrane transporter
2338Integrin beta chain VWA domain
128727Biotin-requiring enzyme
1113Ribosomal protein S17
22phosphotransferase system, EIIB
1113Hydroxymethylglutaryl-coenzyme A reductase
53513FGGY family of carbohydrate kinases, N-terminal domain
17231353FERM central domain
112821Sodium:dicarboxylate symporter family
26111350Enoyl-CoA hydratase/isomerase
5218Ribosomal protein S9/S16
11PTS HPr component phosphorylation site
1438Transcription factor TFIIB repeat
94417Cytidine and deoxycytidylate deaminase zinc-binding region
2114Molybdopterin oxidoreductase
33410Chromo (CHRromatin Organisation MOdifier) domain
185528C1q domain
118625Phosphatidylinositol-specific phospholipase C, Y domain
129627Phosphatidylinositol-specific phospholipase C, X domain
42713D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
2237Malic enzyme, N-terminal domain
22PEP-utilising enzyme, mobile domain
11Bacterial regulatory proteins, gntR family
12146-phosphogluconate dehydrogenase, C-terminal domain
5611Multicopper oxidase
28202674WW domain
1236Ribosomal RNA adenine dimethylase
243190226659WD domain, G-beta repeat
11ATP synthase, Delta/Epsilon chain, long alpha-helix domain
36312Calponin family repeat
63312Heavy-metal-associated domain
11101233Adenylate kinase
3238Phosphoglucomutase/phosphomannomutase, C-terminal domain
1113Ribosomal protein S8
2327Ribosomal protein S11
345833125LIM domain
15101641Regulator of chromosome condensation (RCC1) repeat
1124Ribosomal protein S13/S18
1135Tau and MAP protein, tubulin-binding repeat
11Fimbrial protein
33NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
3431060s Acidic ribosomal protein
813170182CUB domain
44412Prenyltransferase and squalene oxidase repeat
13191042Protein kinase C terminal domain
13131238Spectrin repeat
3115Single-strand binding protein family
22Type II/IV secretion system protein
1124S-adenosylmethionine synthetase, N-terminal domain
11Bacterial regulatory proteins, tetR family
2481648Acyl-CoA dehydrogenase, C-terminal domain
333635104Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
1135Ribonuclease T2 family
1225HSF-type DNA-binding
2226SRP54-type protein, GTPase domain
112Urease alpha-subunit, N-terminal domain
123621Serine carboxypeptidase
139830Apoptosis regulator proteins, Bcl-2 family
2114Ribosomal protein L20
14131441Phosphatidylinositol 3- and 4-kinase
11DeoR C terminal sensor domain
1113Transketolase, thiamine diphosphate binding domain
44311WHEP-TRS domain
74415Inositol monophosphatase family
2237Serine hydroxymethyltransferase
213Iron-containing alcohol dehydrogenase
1337Ribosomal protein L10
77822KOW motif
2226RF-1 domain
47163396Sodium:solute symporter family
22Imidazoleglycerol-phosphate dehydratase
3238DNA polymerase family A
2327IMP dehydrogenase / GMP reductase domain
2226Glucose-6-phosphate dehydrogenase, NAD binding domain
16151243Protein phosphatase 2C
63312Nucleotidyl transferase
1113Carbonic anhydrase
82212Phosphoribulokinase / Uridine kinase family
11Transcriptional regulatory protein, C terminal
85922Fatty acid desaturase
64515MutS domain V
2114Delta-aminolevulinic acid dehydratase
51410Arginase family
88824MCM P-loop domain
2114Squalene/phytoene synthase
55Bacterial extracellular solute-binding proteins, family 5 Middle
23112054FHA domain
11NADH-ubiquinone/plastoquinone oxidoreductase chain 6
48213099AMP-binding enzyme
912930G-protein alpha subunit
235926108HMG (high mobility group) box
325NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
112Cytochrome c oxidase subunit III
44His Kinase A (phospho-acceptor) domain
25142160Armadillo/beta-catenin-like repeat
746580219Tetratricopeptide repeat
7611472262Ion transport protein
2125DNA gyrase/topoisomerase IV, subunit A
1313Binding-protein-dependent transport system inner membrane component
33HlyD membrane-fusion protein of T1SS
5682286Scavenger receptor cysteine-rich domain
24142765Death domain
15131240BRCA1 C Terminus (BRCT) domain
85518Glycosyl transferases group 1
33222984Glycosyl transferase family 2
36253798SAM domain (Sterile alpha motif)
15101540linker histone H1 and H5 family
1113Ribosomal protein L7/L12 C-terminal domain
11Urease, gamma subunit
81514Phosphopantetheine attachment site
53311Formyl transferase
3339Rel homology DNA-binding domain
108826Metallopeptidase family M24
452129174755Leucine Rich Repeat
27111856alpha/beta hydrolase fold
36312RNA polymerase Rpb2, domain 6
44EAL domain
55515PB1 domain
1113Staphylococcal nuclease homologue
27242273Rab-GTPase-TBC domain
13121540Tudor domain
36413WH1 domain
11111234Zinc finger, ZZ type
2215HRDC domain
1612937CBS domain
3227Ribosomal protein L13
4228Ribosomal protein L4/L1 family
3115Clp protease
54514S1 RNA binding domain
22HIUase/Transthyretin family
83617AhpC/TSA family
44412tRNA synthetases class I (W and Y)
11UvrD/REP helicase N-terminal domain
2463161Rhodanese-like domain
23131349Universal stress protein family
37122271Acetyltransferase (GNAT) family
1113SecE/Sec61-gamma subunits of protein translocation complex
43310AIR synthase related protein, N-terminal domain
87823tRNA synthetase class II core domain (G, H, P, S and T)
336SpoU rRNA Methylase family
66Phage integrase family
1113Tetrapyrrole (Corrin/Porphyrin) Methylases
516Glycosyl transferase family, a/b domain
11TonB dependent receptor
919484269PDZ domain
2327Class II Aldolase and Adducin N-terminal domain
35210Interferon regulatory factor transcription factor
55414Diacylglycerol kinase accessory domain
991028Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
69722Fes/CIP4, and EFC/F-BAR homology domain
393439112IQ calmodulin-binding motif
53513Phosphoinositide 3-kinase family, accessory domain (PIK domain)
3339Phospholipase D Active site motif
10141034Regulator of G protein signaling domain
64515GTPase-activator protein for Ras-like GTPase
9121132RasGEF domain
3249RasGEF N-terminal motif
105210117Caspase recruitment domain
274627100RhoGAP domain
344325102RhoGEF domain
17131949SPRY domain
36312RNA polymerase Rpb1, domain 2
8151033Guanylate kinase
991230Gelsolin repeat
18202058UBA/TS-N domain
2411641MAM domain, meprin/A5/mu
1317939Filamin/ABP280 repeat
66416GGL domain
19171955HECT-domain (ubiquitin-transferase)
163221Helix-hairpin-helix motif
1113BRCA2 repeat
66315MSP (Major sperm protein) domain
2327Ribonuclease III domain
2125Region in Clathrin and VPS
46414RanBP1 domain
1124PPIC-type PPIASE domain
10111334Phosphotyrosine interaction domain (PTB/PID)
66820Zn-finger in Ran binding protein and others
403336109Zinc finger C-x8-C-x5-C-x3-H type (and similar)
24293790B-box zinc finger
62513Poly(ADP-ribose) polymerase catalytic domain
2226Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
573661154F-box domain
1113Elongation factor 1 gamma, conserved domain
19111343Calpain family cysteine protease
197834CRAL/TRIO domain
2964470410BTB/POZ domain
20201353Ricin-type beta-trefoil lectin domain
2422248Inhibitor of Apoptosis domain
107623Voltage gated chloride channel
3591862Caspase domain
91515GDSL-like Lipase/Acylhydrolase
3339Poly-adenylate binding protein, unique domain
2428POLO box duplicated region
41192181ABC transporter transmembrane region
63413FAD binding domain
11Condensation domain
3328S-adenosyl-L-homocysteine hydrolase, NAD binding domain
33HAMP domain
2114ribosomal L5P family C-terminus
87621Insulinase (Peptidase family M16)
64616Dehydrogenase E1 component
94619Elongation factor G C-terminus
112Plectin repeat
213TB domain
3339DnaJ central domain
146831185Sulfotransferase domain
11Starch binding domain
3227Ribosomal protein L1p/L10e family
51612TGF-beta propeptide
521329Cation transporting ATPase, C-terminus
521531Cation transporter/ATPase, N-terminus
11OmpA family
2226Aconitase C-terminal domain
224Amino acid kinase family
11N-(5'phosphoribosyl)anthranilate (PRA) isomerase
62513Acyl transferase domain
11Urease beta subunit
4138Dihydrodipicolinate synthetase family
26381983haloacid dehalogenase-like hydrolase
437Glycosyl hydrolases family 2
1152541Glycosyl hydrolases family 18
1113Proliferating cell nuclear antigen, N-terminal domain
1113Adenylosuccinate synthetase
213Asparaginase, N-terminal
72211Peptidase S24-like
1113Inorganic pyrophosphatase
7714Glycosyl hydrolases family 16
825153-hydroxyacyl-CoA dehydrogenase, C-terminal domain
851124Glycosyl hydrolase family 20, catalytic domain
3227HhH-GPD superfamily base excision DNA repair protein
2114AIR carboxylase
106218GMC oxidoreductase
325Asparagine synthase
3227EF-1 guanine nucleotide exchange domain
11Homoserine dehydrogenase
6410Flavin-binding monooxygenase-like
3339tRNA synthetases class I (E and Q), catalytic domain
3126tRNA synthetases class I (R)
53412DM DNA binding domain
44311XPG N-terminal domain
225835Metallo-beta-lactamase superfamily
1311722170F5/8 type C domain
111517Choline/Carnitine o-acyltransferase
1113Putative esterase
1528Furin-like cysteine rich region
1313Glycosyl hydrolase family 9
3227Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
2114Arginosuccinate synthase
2114Electron transfer flavoprotein FAD-binding domain
2439Ezrin/radixin/moesin family
11FHIPEP family
11DnaB-like helicase N terminal domain
42713RNB domain
3249DIX domain
123BTK motif
67417CNH domain
87722Diacylglycerol kinase catalytic domain
23201659Dual specificity phosphatase, catalytic domain
77519MyTH4 domain
86418P21-Rho-binding domain
32192576PX domain
1191434Ras association (RalGDS/AF-6) domain
1191131UBX domain
46414VHS domain
37414ZU5 domain
43310Phosphoinositide 3-kinase C2
11DAHP synthetase I family
74617Carbon-nitrogen hydrolase
538PKD domain
54211Pentapeptide repeats (8 copies)
1326Pumilio-family RNA binding repeat
68620Histone-like transcription factor (CBF/NF-Y) and archaeal histone
3115Pterin binding enzyme
1315ER lumen protein retaining receptor
3227tRNA N6-adenosine threonylcarbamoyltransferase
42410impB/mucB/samB family
44210Phosphoenolpyruvate carboxykinase C-terminal P-loop domain
711523PMP-22/EMP/MP20/Claudin family
1113Ribosomal L15
1124Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
1113Ribosomal prokaryotic L21 protein
1113Ribosomal L29 protein
1113Ribosomal L39 protein
1113Ribosomal S17
2114Ribulose-phosphate 3 epimerase family
1214SNAP-25 family
1315Stathmin family
617Iodothyronine deiodinase
1113Translationally controlled tumour protein
1214Cysteine rich repeat
314Alanine racemase, C-terminal domain
63312RNA pseudouridylate synthase
85619Histone deacetylase domain
6741687Glycosyltransferase family 10 (fucosyltransferase) C-term
1214Runt domain
34310POT family
13161140PWWP domain
19251963SET domain
54413Isochorismatase family
626524151Amiloride-sensitive sodium channel
1411025Permease family
2114Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
112ATP P2X receptor
54514XPG I-region
448Transglutaminase family
1214P53 DNA-binding domain
11Acetokinase family
459DNA photolyase
213Cation-independent mannose-6-phosphate receptor repeat
1214Nebulin repeat
22Nitroreductase family
2136Cytosol aminopeptidase family, catalytic domain
116,7-dimethyl-8-ribityllumazine synthase
213Ribosomal protein S16
75416Acyl CoA binding protein
56516Cullin family
1113Elongation factor TS
5218FAD binding domain
1225O-methyltransferase domain
123EamA-like transporter family
1110930ThiF family
1113Ribosomal family S4e
11Sec-independent protein translocase protein (TatC)
62513Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
101718Ammonium Transporter Family
961126Sulfate permease family
119727MATH domain
2226Uncharacterized protein family UPF0004
1113Transaldolase/Fructose-6-phosphate aldolase
11GTP cyclohydrolase II
113,4-dihydroxy-2-butanone 4-phosphate synthase
347Transglutaminase family, C-terminal ig like domain
54312Adaptor complexes medium subunit family
2226Dipeptidyl peptidase IV (DPP IV) N-terminal region
311216Lamin Tail Domain
921930Glycosyl hydrolase family 3 N terminal domain
1113Ribosomal protein L44
106521Sodium:sulfate symporter transmembrane region
1113DNA-dependent RNA polymerase
72615FAD binding domain in molybdopterin dehydrogenase
1113Glycosyl transferase family 4
68620HCO3- transporter family
46313Nucleosome assembly protein (NAP)
1113GMP synthase C terminal domain
11LAGLIDADG endonuclease
63716Adenosine/AMP deaminase
5139Oxidoreductase FAD-binding domain
2125Thioesterase domain
1113UDP-glucose/GDP-mannose dehydrogenase family, central domain
11DNA gyrase B subunit, carboxyl terminus
1124Carbamoyl-phosphate synthase small chain, CPSase domain
84517PAS fold
77Diguanylate cyclase, GGDEF domain
2237Probable molybdopterin binding domain
56516Sec1 family
2417GDP dissociation inhibitor
44513Sodium/hydrogen exchanger family
2327RNA polymerase Rpb3/RpoA insert domain
512522Inward rectifier potassium channel transmembrane domain
53412Initiation factor 2 subunit family
112PQQ enzyme repeat
1113Electron transfer flavoprotein domain
1113Ribosomal S3Ae family
112Ribosomal L27 protein
2114STAT protein, all-alpha domain
22Bacterial regulatory protein, arsR family
62311TatD related DNase
54514Inhibitor of apoptosis-promoting Bax1
1214Eukaryotic DNA topoisomerase I, catalytic core
38920Receptor L domain
3328Dynamin central region
11FecCD transport family
311519Somatomedin B domain
1113Syndecan domain
4156-O-methylguanine DNA methyltransferase, DNA binding domain
33Lrp/AsnC ligand binding domain
63413Carboxyl transferase domain
34310UbiA prenyltransferase family
415DegT/DnrJ/EryC1/StrS aminotransferase family
4228Endoribonuclease L-PSP
2226Vinculin family
145Phosphorylase superfamily
3328Cadherin cytoplasmic region
11Mannose-6-phosphate isomerase
53210Cys/Met metabolism PLP-dependent enzyme
1161229Glycosyl hydrolases family 31
11Myc amino-terminal region
1113NADH ubiquinone oxidoreductase, 20 Kd subunit
11ABC-2 type transporter
18110Bestrophin, RFP-TM, chloride channel
1214Amino-transferase class IV
3328Activin types I and II receptor domain
64515CDP-alcohol phosphatidyltransferase
1511834Calpain large subunit, domain III
42410ATP dependent DNA ligase domain
415FMN-dependent dehydrogenase
2114Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
42393-beta hydroxysteroid dehydrogenase/isomerase family
65617Glycosyl hydrolases family 38 N-terminal domain
11Nitrite and sulphite reductase 4Fe-4S domain
268Hint module
22KDPG and KHG aldolase
321520Copper type II ascorbate-dependent monooxygenase, N-terminal domain
1113Ribosomal protein S18
1113Hedgehog amino-terminal signalling domain
1113Clathrin light chain
213Galactose-1-phosphate uridyl transferase, N-terminal domain
43310Ubiquitin carboxyl-terminal hydrolase, family 1
112Ribosomal protein S19e
1113Ribosomal protein S6e
691935123Receptor family ligand binding region
46313Transcription factor S-II (TFIIS)
2114Omp85 superfamily domain
78722emp24/gp25L/p24 family/GOLD
1214NifU-like domain
3115Cyclin-dependent kinase regulatory subunit
22Dihydrodipicolinate reductase, N-terminus
1113F-actin capping protein, beta subunit
11Semialdehyde dehydrogenase, NAD binding domain
61310DNA mismatch repair protein, C-terminal domain
2125Dephospho-CoA kinase
82818MAPEG family
1214G10 protein
2125Heme oxygenase
2114Succinate dehydrogenase/Fumarate reductase transmembrane subunit
21142-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
2125CD36 family
3227DNA topoisomerase
11Elongation factor P (EF-P) OB domain
2114Enhancer of rudimentary
112Glucose inhibited division protein A
2226Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
11Peptidase family U32
2226RNA 3'-terminal phosphate cyclase
756183' exoribonuclease family, domain 1
2114tRNA-splicing ligase RtcB
1113tRNA pseudouridine synthase D (TruD)
4116Coenzyme A transferase
12161139SPFH domain / Band 7 family
1214Cytidylyltransferase family
112Formamidopyrimidine-DNA glycosylase N-terminal domain
46313GDA1/CD39 (nucleoside phosphatase) family
1161128GNS1/SUR4 family
1113Hydroxymethylglutaryl-coenzyme A synthase N terminal
3238Inosine-uridine preferring nucleoside hydrolase
1113Ribosomal protein L21e
1113Ribosomal protein L36e
2114Ribosomal protein L6e
35311Phosphatidylethanolamine-binding protein
3339RIO1 family
1214TSC-22/dip/bun family
2114Tub family
6129Alanine racemase, N-terminal domain
1214Uncharacterized protein family UPF0016
2114Putative RNA methylase family UPF0020
2114PP-loop family
1113Shwachman-Bodian-Diamond syndrome (SBDS) protein
112SNO glutamine amidotransferase family
112Urocanase Rossmann-like domain
2114Translation initiation factor 1A / IF-1
22Asp/Glu/Hydantoin racemase
77Copper amine oxidase, enzyme domain
4228Dihydroorotate dehydrogenase
1135Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
1214Lysyl oxidase
2338Macrophage migration inhibitory factor (MIF)
7551716S rRNA methyltransferase RsmB/F
1214RNA polymerase Rpb5, C-terminal domain
1124RNA polymerase Rpb6
55414RNA polymerase Rpb3/Rpb11 dimerisation domain
1315RNA polymerases N / 8 kDa subunit
112Peptidyl-tRNA hydrolase
112Ribosomal protein L17
11Ribosomal protein L31
1113Ribosomal protein L31e
1113Ribosomal protein L34e
2114Ribosomal protein S28e
2226Ribosomal protein S8e
213Shikimate kinase
2417Uncharacterized protein family UPF0029
22Sulfurtransferase TusA
63413Dihydrouridine synthase (Dus)
3115Uroporphyrinogen decarboxylase (URO-D)
2125ubiE/COQ5 methyltransferase family
1326NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
1113Adenylate cyclase associated (CAP) N terminal
1113Casein kinase II regulatory subunit
11Cytochrome c oxidase subunit Vb
58316Clathrin adaptor complex small chain
3115Coproporphyrinogen III oxidase
11Prokaryotic diacylglycerol kinase
21811Dynein light chain type 1
4228Ergosterol biosynthesis ERG4/ERG24 family
3216DNA/RNA non-specific endonuclease
11Mur ligase family, catalytic domain
2114GTP cyclohydrolase I
112Glycosyl hydrolases family 39
73515HIT domain
123Indoleamine 2,3-dioxygenase
11Mannitol dehydrogenase Rossmann domain
1113Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
415NNMT/PNMT/TEMT family
66618Oxysterol-binding protein
1113Phosphomannose isomerase type I
4239Protein prenyltransferase alpha subunit repeat
11136-pyruvoyl tetrahydropterin synthase
2114Pyridoxamine 5'-phosphate oxidase
3126Membrane dipeptidase (Peptidase family M19)
1113Ribosomal protein L19
3227Ribosomal protein L24e
1124Ribosomal protein L35Ae
77620Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
1113Ribosomal protein S21e
2114Ribosomal protein S7e
43411Translation initiation factor SUI1
1113Putative undecaprenyl diphosphate synthase
1113Carbohydrate kinase
1113Thioredoxin-like [2Fe-2S] ferredoxin
1113SAICAR synthetase
112Xylose isomerase-like TIM barrel
3227Alanine dehydrogenase/PNT, C-terminal domain
4138Aldose 1-epimerase
11Chorismate synthase
112Cytochrome c/c1 heme lyase
144826FAD dependent oxidoreductase
1113F-actin capping protein alpha subunit
1113Formate--tetrahydrofolate ligase
54110LBP / BPI / CETP family, N-terminal domain
11Malate synthase
1113Myelin proteolipid protein (PLP or lipophilin)
1214Ribosomal protein L19e
213Ribosomal protein L9, N-terminal domain
1113Ribosomal protein S24e
1113Ribosomal protein S26e
66416Membrane-associating domain
1214TEA/ATTS domain
2114XPA protein N-terminal
2125Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
1225Thymosin beta-4 family
11Prokaryotic cytochrome b561
1113Ribosomal protein L13e
11Lysosome-associated membrane glycoprotein (Lamp)
2125Telomere recombination
5229Glycosyl hydrolases family 35
1591034CAP-Gly domain
11FlhB HrpN YscU SpaS Family
52613Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
11Arginine repressor, DNA binding domain
3137DSBA-like thioredoxin domain
22Pyruvate phosphate dikinase, AMP/ATP-binding domain
2114Pterin 4 alpha carbinolamine dehydratase
1438mRNA capping enzyme, catalytic domain
3148Death effector domain
55717OB-fold nucleic acid binding domain
4239SAND domain
2456156362Kelch motif
628Lipoprotein amino terminal region
1113Ribonuclease HII
20201959FYVE zinc finger
46414RIH domain
115'-3' exonuclease, C-terminal SAM fold
11DHH family
612422Sec7 domain
74213NAD dependent epimerase/dehydratase family
2114Porphobilinogen deaminase, dipyromethane cofactor binding domain
2215SIS domain
33Avidin family
2215Phosphate transporter family
610622ARID/BRIGHT DNA binding domain
246SEA domain
10810327238Collagen triple helix repeat (20 copies)
881026Fz domain
112Chromo shadow domain
1113Clathrin propeller repeat
213Topoisomerase DNA binding C4 zinc finger
1081129JAB1/Mov34/MPN/PAD-1 ubiquitin protease
15141645PCI domain
2252047Astacin (Peptidase family M12A)
54514Angiotensin-converting enzyme
62715Sema domain
112Ephrin receptor ligand binding domain
3126tRNA synthetases class I (C) catalytic domain
144624Oxidoreductase family, NAD-binding Rossmann fold
3227tRNA synthetases class II core domain (F)
26311Fibrillar collagen C-terminal domain
2215tRNA synthetases class II (A)
10131033Putative GTPase activating protein for Arf
43411C-terminal tandem repeated domain in type 4 procollagen
73515Delta serrate ligand