PFAM Domains • Massariosphaeria phaeospora CBS 611.86 v1.0
| Annotations/Genomes | Total | Annotation Description | ||||||
|---|---|---|---|---|---|---|---|---|
 PFAMs | 10,123 | 9,420 | 7,592 | 10,741 | 9,884 | 7,245 | 55,005 | |
| 50 | 55 | 45 | 57 | 52 | 41 | 300 | ATPase family associated with various cellular activities (AAA) | |
| 58 | 50 | 33 | 44 | 43 | 33 | 261 | ABC transporter | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | ATP synthase alpha/beta family, nucleotide-binding domain | |
| 1 | 1 | 1 | 3 | EGF-like domain | ||||
| 14 | 15 | 14 | 16 | 14 | 14 | 87 | Elongation factor Tu GTP binding domain | |
| 10 | 13 | 10 | 10 | 11 | 8 | 62 | Helix-loop-helix DNA-binding domain | |
| 3 | 3 | 4 | 3 | 3 | 2 | 18 | Hsp20/alpha crystallin family | |
| 9 | 7 | 8 | 13 | 8 | 7 | 52 | Hsp70 protein | |
| 8 | 10 | 8 | 7 | 8 | 9 | 50 | KH domain | |
| 1 | 1 | 1 | 1 | 1 | 5 | SH2 domain | ||
| 22 | 22 | 21 | 14 | 27 | 22 | 128 | SH3 domain | |
| 10 | 10 | 10 | 11 | 10 | 10 | 61 | Actin | |
| 71 | 113 | 50 | 28 | 126 | 36 | 424 | Ankyrin repeat | |
| 2 | 5 | 1 | 9 | 5 | 22 | PAN domain | ||
| 7 | 7 | 7 | 8 | 7 | 7 | 43 | ADP-ribosylation factor family | |
| 10 | 12 | 6 | 30 | 10 | 9 | 77 | Eukaryotic aspartyl protease | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Cyclic nucleotide-binding domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Cytochrome c | |
| 1 | 1 | 1 | 1 | 3 | 2 | 9 | Double-stranded RNA binding motif | |
| 17 | 20 | 17 | 4 | 18 | 14 | 90 | EF hand | |
| 1 | 1 | 1 | 1 | 1 | 5 | 4Fe-4S binding domain | ||
| 3 | 3 | 2 | 1 | 2 | 2 | 13 | Fibronectin type III domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Globin | |
| 14 | 18 | 13 | 14 | 17 | 7 | 83 | Glutathione S-transferase, C-terminal domain | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain | |
| 10 | 9 | 6 | 6 | 9 | 8 | 48 | Homeodomain | |
| 5 | 3 | 3 | 3 | 4 | 3 | 21 | lactate/malate dehydrogenase, NAD binding domain | |
| 1 | 1 | 2 | Low-density lipoprotein receptor repeat class B | |||||
| 4 | 5 | 5 | 4 | 4 | 4 | 26 | Myosin head (motor domain) | |
| 134 | 135 | 95 | 151 | 151 | 52 | 718 | Cytochrome P450 | |
| 164 | 196 | 107 | 161 | 160 | 104 | 892 | Protein kinase domain | |
| 14 | 23 | 16 | 14 | 21 | 11 | 99 | Pyridine nucleotide-disulphide oxidoreductase | |
| 24 | 24 | 23 | 27 | 26 | 23 | 147 | Ras family | |
| 22 | 24 | 15 | 19 | 28 | 19 | 127 | Response regulator receiver domain | |
| 2 | 1 | 6 | 4 | 2 | 15 | RNase H | ||
| 57 | 60 | 62 | 53 | 62 | 61 | 355 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | |
| 3 | 3 | 2 | 3 | 3 | 3 | 17 | Copper/zinc superoxide dismutase (SODC) | |
| 2 | 2 | 2 | 3 | 2 | 2 | 13 | Iron/manganese superoxide dismutases, alpha-hairpin domain | |
| 14 | 17 | 7 | 23 | 12 | 9 | 82 | Subtilase family | |
| 139 | 71 | 45 | 54 | 69 | 35 | 413 | Sugar (and other) transporter | |
| 13 | 11 | 11 | 11 | 10 | 10 | 66 | Thioredoxin | |
| 2 | 1 | 2 | 2 | 2 | 1 | 10 | Trypsin | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Tubulin/FtsZ family, GTPase domain | |
| 3 | 5 | 2 | 1 | 6 | 3 | 20 | von Willebrand factor type A domain | |
| 75 | 71 | 57 | 20 | 79 | 57 | 359 | Zinc finger, C2H2 type | |
| 60 | 87 | 46 | 8 | 74 | 60 | 335 | Zinc finger, C3HC4 type (RING finger) | |
| 4 | 9 | 7 | 3 | 6 | 11 | 40 | Zinc knuckle | |
| 2 | 4 | 2 | 2 | 2 | 2 | 14 | Protein-tyrosine phosphatase | |
| 179 | 164 | 96 | 132 | 175 | 85 | 831 | short chain dehydrogenase | |
| 86 | 73 | 41 | 62 | 79 | 43 | 384 | Zinc-binding dehydrogenase | |
| 7 | 6 | 6 | 6 | 6 | 6 | 37 | Thiolase, N-terminal domain | |
| 23 | 27 | 18 | 24 | 18 | 9 | 119 | Beta-ketoacyl synthase, N-terminal domain | |
| 7 | 6 | 6 | 3 | 6 | 4 | 32 | 2Fe-2S iron-sulfur cluster binding domain | |
| 1 | 1 | 2 | Papain family cysteine protease | |||||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Enolase, C-terminal TIM barrel domain | |
| 10 | 8 | 9 | 8 | 8 | 8 | 51 | Glutamine amidotransferase class-I | |
| 10 | 10 | 10 | 10 | 10 | 10 | 60 | TCP-1/cpn60 chaperonin family | |
| 4 | 3 | 3 | 3 | 3 | 3 | 19 | Glutamine synthetase, catalytic domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Triosephosphate isomerase | |
| 20 | 17 | 13 | 21 | 17 | 15 | 103 | E1-E2 ATPase | |
| 7 | 7 | 8 | 17 | 9 | 8 | 56 | Core histone H2A/H2B/H3/H4 | |
| 1 | 1 | 2 | Copper binding proteins, plastocyanin/azurin family | |||||
| 10 | 8 | 5 | 6 | 5 | 3 | 37 | Alpha amylase, catalytic domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Phorbol esters/diacylglycerol binding domain (C1 domain) | |
| 6 | 8 | 7 | 8 | 7 | 6 | 42 | Bacterial transferase hexapeptide (six repeats) | |
| 5 | 3 | 3 | 7 | 4 | 3 | 25 | tRNA synthetases class I (I, L, M and V) | |
| 7 | 7 | 7 | 8 | 8 | 6 | 43 | Cyclin, N-terminal domain | |
| 33 | 27 | 18 | 20 | 31 | 12 | 141 | Carboxylesterase family | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | DNA polymerase family B | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | ATP synthase subunit C | |
| 5 | 7 | 7 | 5 | 6 | 6 | 36 | Peroxidase | |
| 14 | 10 | 4 | 13 | 15 | 5 | 61 | Beta-lactamase | |
| 4 | 4 | 2 | 3 | 3 | 3 | 19 | C-5 cytosine-specific DNA methylase | |
| 29 | 32 | 21 | 23 | 27 | 25 | 157 | Calcineurin-like phosphoesterase | |
| 16 | 12 | 14 | 12 | 9 | 6 | 69 | Cellulase (glycosyl hydrolase family 5) | |
| 7 | 7 | 7 | 7 | 8 | 8 | 44 | tRNA synthetases class II (D, K and N) | |
| 43 | 41 | 38 | 40 | 40 | 38 | 240 | Mitochondrial carrier protein | |
| 1 | 1 | 2 | recA bacterial DNA recombination protein | |||||
| 29 | 19 | 13 | 21 | 15 | 14 | 111 | Aminotransferase class I and II | |
| 9 | 8 | 8 | 5 | 9 | 8 | 47 | Phosphoribosyl transferase domain | |
| 10 | 11 | 10 | 10 | 11 | 10 | 62 | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Phosphoglycerate kinase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S4/S9 N-terminal domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S12/S23 | |
| 1 | 1 | 1 | 1 | 1 | 5 | Bacterial regulatory helix-turn-helix proteins, AraC family | ||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Chaperonin 10 Kd subunit | |
| 12 | 12 | 11 | 9 | 11 | 11 | 66 | C2 domain | |
| 19 | 18 | 18 | 10 | 20 | 19 | 104 | PH domain | |
| 11 | 8 | 6 | 12 | 10 | 6 | 53 | bZIP transcription factor | |
| 40 | 20 | 16 | 20 | 20 | 14 | 130 | Aldehyde dehydrogenase family | |
| 332 | 204 | 117 | 167 | 212 | 96 | 1,128 | Fungal Zn(2)-Cys(6) binuclear cluster domain | |
| 25 | 23 | 20 | 22 | 26 | 21 | 137 | Cytochrome b5-like Heme/Steroid binding domain | |
| 5 | 3 | 3 | 3 | 5 | 3 | 22 | Oxidoreductase molybdopterin binding domain | |
| 20 | 16 | 11 | 13 | 19 | 14 | 93 | Oxidoreductase NAD-binding domain | |
| 27 | 26 | 24 | 28 | 27 | 23 | 155 | SNF2 family N-terminal domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S7p/S5e | |
| 25 | 24 | 22 | 26 | 27 | 22 | 146 | Ubiquitin-conjugating enzyme | |
| 10 | 7 | 6 | 6 | 7 | 6 | 42 | Isocitrate/isopropylmalate dehydrogenase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal Proteins L2, RNA binding domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Hsp90 protein | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain | |
| 1 | 1 | 1 | 1 | 2 | 1 | 7 | Dihydrofolate reductase | |
| 8 | 11 | 5 | 7 | 21 | 18 | 70 | Chitin recognition protein | |
| 4 | 3 | 3 | 3 | 4 | 2 | 19 | Cysteine-rich secretory protein family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal protein S3, C-terminal domain | |
| 5 | 5 | 7 | 7 | 6 | 3 | 33 | Cupin | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Annexin | |
| 1 | 1 | 1 | 2 | 2 | 1 | 8 | Eukaryotic-type carbonic anhydrase | |
| 1 | 1 | 2 | Chalcone and stilbene synthases, N-terminal domain | |||||
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | |
| 5 | 5 | 5 | 6 | 6 | 4 | 31 | Catalase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Disintegrin | |
| 1 | 1 | 1 | 2 | 1 | 6 | UDP-glucoronosyl and UDP-glucosyl transferase | ||
| 11 | 10 | 6 | 7 | 7 | 5 | 46 | Aminotransferase class-III | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S19 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | DNA gyrase B | |
| 9 | 6 | 4 | 6 | 6 | 5 | 36 | Thiamine pyrophosphate enzyme, central domain | |
| 5 | 4 | 4 | 4 | 4 | 4 | 25 | Lyase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Glutamate/Leucine/Phenylalanine/Valine dehydrogenase | |
| 2 | 1 | 1 | 1 | 5 | Sodium:neurotransmitter symporter family | |||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Adenylate and Guanylate cyclase catalytic domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | ATP synthase delta (OSCP) subunit | |
| 1 | 2 | 1 | 1 | 2 | 1 | 8 | Orotidine 5'-phosphate decarboxylase / HUMPS family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Indole-3-glycerol phosphate synthase | |
| 1 | 1 | 2 | 1 | 1 | 6 | Aromatic amino acid lyase | ||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Pyruvate kinase, barrel domain | |
| 12 | 10 | 10 | 10 | 11 | 10 | 63 | Kinesin motor domain | |
| 32 | 36 | 28 | 26 | 38 | 37 | 197 | DnaJ domain | |
| 14 | 14 | 14 | 14 | 14 | 14 | 84 | Proteasome subunit | |
| 8 | 6 | 4 | 5 | 9 | 4 | 36 | Major intrinsic protein | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | ATP synthase | |
| 6 | 2 | 3 | 3 | 3 | 2 | 19 | Glycosyl hydrolase family 1 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | 3'5'-cyclic nucleotide phosphodiesterase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Profilin | |
| 1 | 1 | 1 | 2 | 1 | 1 | 7 | Ribosomal protein L22p/L17e | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L14p/L23e | |
| 12 | 13 | 10 | 11 | 12 | 9 | 67 | Ubiquitin family | |
| 5 | 4 | 5 | 5 | 5 | 5 | 29 | Cofilin/tropomyosin-type actin-binding protein | |
| 2 | 2 | 2 | 3 | 2 | 2 | 13 | 14-3-3 protein | |
| 4 | 5 | 5 | 3 | 6 | 4 | 27 | Alkaline phosphatase | |
| 7 | 6 | 4 | 5 | 9 | 6 | 37 | Zinc carboxypeptidase | |
| 35 | 28 | 25 | 27 | 33 | 18 | 166 | Aldo/keto reductase family | |
| 12 | 14 | 19 | 7 | 15 | 15 | 82 | Myb-like DNA-binding domain | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Forkhead domain | |
| 4 | 3 | 1 | 1 | 2 | 11 | Glycosyl hydrolases family 32 N-terminal domain | ||
| 1 | 1 | 1 | 2 | 1 | 1 | 7 | Ribosomal protein L16p/L10e | |
| 3 | 2 | 2 | 2 | 3 | 3 | 15 | Ribosomal protein S14p/S29e | |
| 5 | 4 | 4 | 4 | 5 | 4 | 26 | FKBP-type peptidyl-prolyl cis-trans isomerase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Glutathione peroxidase | |
| 2 | 2 | 1 | 2 | 1 | 8 | |||
| 9 | 7 | 6 | 7 | 8 | 5 | 42 | Flavodoxin | |
| 1 | 1 | Protamine P1 | ||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Calreticulin family | |
| 15 | 20 | 12 | 16 | 16 | 21 | 100 | Common central domain of tyrosinase | |
| 8 | 6 | 8 | 8 | 9 | 7 | 46 | Aminotransferase class-V | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribonucleotide reductase, small chain | |
| 41 | 36 | 37 | 43 | 42 | 38 | 237 | DEAD/DEAH box helicase | |
| 78 | 69 | 70 | 74 | 81 | 69 | 441 | Helicase conserved C-terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) | |
| 1 | 2 | 2 | 2 | 2 | 2 | 11 | Ribosomal protein L23 | |
| 1 | 1 | 1 | 1 | 3 | 1 | 8 | Pyridoxal-dependent decarboxylase, C-terminal sheet domain | |
| 1 | 2 | 2 | 1 | 1 | 2 | 9 | Ribosomal protein L5 | |
| 6 | 6 | 6 | 6 | 7 | 6 | 37 | Pyridoxal-dependent decarboxylase conserved domain | |
| 3 | 2 | 3 | 3 | 2 | 2 | 15 | Citrate synthase, C-terminal domain | |
| 5 | 5 | 5 | 5 | 5 | 5 | 30 | GHMP kinases N terminal domain | |
| 8 | 7 | 7 | 5 | 8 | 6 | 41 | Biotin carboxylase, N-terminal domain | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | Tryptophan synthase alpha chain | |
| 13 | 10 | 11 | 12 | 11 | 9 | 66 | Pyridoxal-phosphate dependent enzyme | |
| 14 | 16 | 14 | 15 | 15 | 13 | 87 | NUDIX domain | |
| 7 | 5 | 5 | 5 | 8 | 6 | 36 | pfkB family carbohydrate kinase | |
| 5 | 10 | 4 | 3 | 6 | 28 | Glycosyl hydrolases family 28 | ||
| 1 | 1 | 1 | 3 | Luciferase-like monooxygenase | ||||
| 2 | 2 | 2 | 3 | 2 | 2 | 13 | Ribosomal protein L3 | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L11, RNA binding domain | |
| 15 | 16 | 12 | 14 | 14 | 13 | 84 | Histidine phosphatase superfamily (branch 1) | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Thymidylate synthase | |
| 1 | 1 | 1 | 3 | Lipoxygenase | ||||
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | ATP synthase alpha/beta chain, C terminal domain | |
| 5 | 5 | 5 | 5 | 5 | 4 | 29 | Calponin homology (CH) domain | |
| 4 | 4 | 5 | 3 | 5 | 4 | 25 | Glutamine amidotransferases class-II | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S15 | |
| 1 | 1 | 'Cold-shock' DNA-binding domain | ||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Thaumatin family | |
| 2 | 2 | 2 | 2 | 1 | 1 | 10 | Fructose-1-6-bisphosphatase, N-terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribonucleotide reductase, all-alpha domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S2 | |
| 2 | 1 | 2 | 2 | 2 | 2 | 11 | SRF-type transcription factor (DNA-binding and dimerisation domain) | |
| 7 | 6 | 6 | 7 | 8 | 6 | 40 | GATA zinc finger | |
| 55 | 53 | 39 | 15 | 41 | 36 | 239 | Amino acid permease | |
| 5 | 5 | 4 | 6 | 5 | 5 | 30 | Prolyl oligopeptidase family | |
| 3 | 2 | 2 | 3 | 2 | 3 | 15 | Ribosomal protein L30p/L7e | |
| 10 | 11 | 8 | 9 | 10 | 6 | 54 | Histidine phosphatase superfamily (branch 2) | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Respiratory-chain NADH dehydrogenase, 30 Kd subunit | |
| 6 | 5 | 5 | 4 | 4 | 4 | 28 | Aconitase family (aconitate hydratase) | |
| 6 | 5 | 4 | 5 | 6 | 4 | 30 | Glycosyl hydrolase family 10 | |
| 2 | 3 | 4 | 2 | 4 | 3 | 18 | Glycosyl hydrolases family 17 | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S5, N-terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Nucleoside diphosphate kinase | |
| 1 | 1 | 2 | Tetraspanin family | |||||
| 1 | 1 | 2 | 2 | 1 | 7 | Ribosomal protein S10p/S20e | ||
| 5 | 5 | 4 | 5 | 5 | 4 | 28 | Arrestin (or S-antigen), N-terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Phosphoglucose isomerase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Carbohydrate phosphorylase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | SecY translocase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Respiratory-chain NADH dehydrogenase, 49 Kd subunit | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L6 | |
| 3 | 3 | 4 | 5 | 3 | 3 | 21 | Polyprenyl synthetase | |
| 5 | 5 | 5 | 4 | 5 | 5 | 29 | Hexokinase | |
| 8 | 10 | 6 | 11 | 7 | 6 | 48 | Dynamin family | |
| 1 | 1 | Biopterin-dependent aromatic amino acid hydroxylase | ||||||
| 1 | 1 | 1 | 4 | 1 | 1 | 9 | Transcription factor TFIID (or TATA-binding protein, TBP) | |
| 6 | 5 | 4 | 3 | 8 | 4 | 30 | Rieske [2Fe-2S] domain | |
| 2 | 1 | 3 | Phytochrome region | |||||
| 9 | 8 | 9 | 7 | 10 | 8 | 51 | Biotin-requiring enzyme | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Phosphofructokinase | |
| 2 | 1 | 2 | 2 | 2 | 2 | 11 | Ribosomal protein S17 | |
| 1 | 1 | 1 | 1 | 2 | 1 | 7 | Hydroxymethylglutaryl-coenzyme A reductase | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | FGGY family of carbohydrate kinases, N-terminal domain | |
| 1 | 1 | 2 | Sodium:dicarboxylate symporter family | |||||
| 17 | 11 | 9 | 7 | 13 | 12 | 69 | Enoyl-CoA hydratase/isomerase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S9/S16 | |
| 2 | 2 | 2 | 2 | 3 | 2 | 13 | Transcription factor TFIIB repeat | |
| 8 | 7 | 6 | 7 | 7 | 5 | 40 | Cytidine and deoxycytidylate deaminase zinc-binding region | |
| 1 | 1 | 1 | 1 | 2 | 1 | 7 | Molybdopterin oxidoreductase | |
| 4 | 6 | 6 | 6 | 4 | 6 | 32 | Chromo (CHRromatin Organisation MOdifier) domain | |
| 3 | 3 | 2 | 3 | 3 | 3 | 17 | Phosphatidylinositol-specific phospholipase C, Y domain | |
| 3 | 3 | 2 | 4 | 3 | 4 | 19 | Phosphatidylinositol-specific phospholipase C, X domain | |
| 14 | 9 | 8 | 9 | 10 | 8 | 58 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Malic enzyme, N-terminal domain | |
| 1 | 1 | PEP-utilising enzyme, mobile domain | ||||||
| 1 | 1 | 2 | 1 | 2 | 2 | 9 | 6-phosphogluconate dehydrogenase, C-terminal domain | |
| 12 | 13 | 15 | 14 | 10 | 4 | 68 | Multicopper oxidase | |
| 8 | 13 | 9 | 10 | 12 | 11 | 63 | WW domain | |
| 1 | 1 | 1 | 2 | 1 | 1 | 7 | Ribosomal RNA adenine dimethylase | |
| 2 | 1 | 2 | 2 | 2 | 2 | 11 | Yeast PIR protein repeat | |
| 116 | 110 | 118 | 105 | 134 | 103 | 686 | WD domain, G-beta repeat | |
| 7 | 5 | 4 | 5 | 5 | 4 | 30 | Heavy-metal-associated domain | |
| 3 | 5 | 3 | 4 | 4 | 4 | 23 | Adenylate kinase | |
| 2 | 2 | 2 | 3 | 2 | 2 | 13 | Phosphoglucomutase/phosphomannomutase, C-terminal domain | |
| 2 | 2 | 1 | 2 | 2 | 2 | 11 | Ribosomal protein S8 | |
| 2 | 2 | 2 | 2 | 1 | 1 | 10 | Ribosomal protein S11 | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | LIM domain | |
| 2 | 2 | 1 | 1 | 1 | 1 | 8 | Matrixin | |
| 2 | 2 | 1 | 4 | 2 | 2 | 13 | Regulator of chromosome condensation (RCC1) repeat | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein S13/S18 | |
| 2 | 2 | 3 | 2 | 2 | 2 | 13 | chorismate binding enzyme | |
| 4 | 4 | 4 | 3 | 4 | 3 | 22 | 60s Acidic ribosomal protein | |
| 6 | 4 | 4 | 4 | 4 | 4 | 26 | Prenyltransferase and squalene oxidase repeat | |
| 6 | 5 | 6 | 4 | 6 | 6 | 33 | Protein kinase C terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Single-strand binding protein family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | S-adenosylmethionine synthetase, N-terminal domain | |
| 8 | 8 | 7 | 7 | 10 | 8 | 48 | Bromodomain | |
| 16 | 16 | 14 | 9 | 16 | 14 | 85 | Acyl-CoA dehydrogenase, C-terminal domain | |
| 14 | 15 | 16 | 18 | 15 | 15 | 93 | Ubiquitin carboxyl-terminal hydrolase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal protein L36 | |
| 2 | 2 | 2 | 2 | 2 | 1 | 11 | Ribonuclease T2 family | |
| 3 | 2 | 2 | 3 | 3 | 3 | 16 | HSF-type DNA-binding | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | SRP54-type protein, GTPase domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Urease alpha-subunit, N-terminal domain | |
| 10 | 14 | 11 | 11 | 12 | 4 | 62 | Serine carboxypeptidase | |
| 8 | 8 | 8 | 8 | 8 | 8 | 48 | Phosphatidylinositol 3- and 4-kinase | |
| 4 | 2 | 1 | 1 | 3 | 1 | 12 | Transketolase, thiamine diphosphate binding domain | |
| 4 | 4 | 4 | 3 | 3 | 4 | 22 | Glycosyl hydrolases family 11 | |
| 7 | 5 | 4 | 3 | 5 | 3 | 27 | Inositol monophosphatase family | |
| 4 | 4 | 4 | 3 | 4 | 4 | 23 | Glutaredoxin | |
| 4 | 3 | 3 | 2 | 3 | 3 | 18 | Isocitrate lyase family | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Serine hydroxymethyltransferase | |
| 4 | 4 | 4 | 4 | 4 | 3 | 23 | Iron-containing alcohol dehydrogenase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L10 | |
| 4 | 5 | 3 | 4 | 4 | 3 | 23 | KOW motif | |
| 1 | 1 | 1 | 1 | 1 | 5 | Ribosomal protein L34 | ||
| 1 | 1 | Negative factor, (F-Protein) or Nef | ||||||
| 3 | 2 | 2 | 3 | 2 | 2 | 14 | RF-1 domain | |
| 4 | 3 | 2 | 1 | 2 | 2 | 14 | Sodium:solute symporter family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Imidazoleglycerol-phosphate dehydratase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | DNA polymerase family A | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | IMP dehydrogenase / GMP reductase domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Glucose-6-phosphate dehydrogenase, NAD binding domain | |
| 6 | 6 | 6 | 6 | 7 | 5 | 36 | Protein phosphatase 2C | |
| 2 | 3 | 3 | 3 | 3 | 3 | 17 | Nucleotidyl transferase | |
| 3 | 3 | 3 | 4 | 3 | 3 | 19 | Carbonic anhydrase | |
| 1 | 1 | 1 | 3 | 1 | 1 | 8 | Phosphoribulokinase / Uridine kinase family | |
| 7 | 5 | 4 | 6 | 7 | 4 | 33 | Fatty acid desaturase | |
| 6 | 6 | 6 | 6 | 6 | 6 | 36 | MutS domain V | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Delta-aminolevulinic acid dehydratase | |
| 6 | 4 | 4 | 4 | 6 | 3 | 27 | Arginase family | |
| 6 | 6 | 6 | 7 | 6 | 6 | 37 | MCM P-loop domain | |
| 2 | 2 | 2 | 3 | 2 | 2 | 13 | Squalene/phytoene synthase | |
| 8 | 10 | 7 | 8 | 8 | 9 | 50 | FHA domain | |
| 54 | 47 | 41 | 34 | 50 | 38 | 264 | AMP-binding enzyme | |
| 4 | 4 | 4 | 6 | 4 | 4 | 26 | G-protein alpha subunit | |
| 9 | 7 | 9 | 11 | 8 | 8 | 52 | HMG (high mobility group) box | |
| 18 | 21 | 12 | 17 | 25 | 16 | 109 | His Kinase A (phospho-acceptor) domain | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | Armadillo/beta-catenin-like repeat | |
| 30 | 23 | 31 | 9 | 42 | 23 | 158 | Tetratricopeptide repeat | |
| 3 | 4 | 3 | 2 | 3 | 2 | 17 | Ion transport protein | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | DNA gyrase/topoisomerase IV, subunit A | |
| 13 | 13 | 12 | 7 | 12 | 11 | 68 | BRCA1 C Terminus (BRCT) domain | |
| 7 | 8 | 7 | 6 | 6 | 6 | 40 | Glycosyl transferases group 1 | |
| 3 | 4 | 3 | 2 | 4 | 3 | 19 | Glycosyl transferase family 2 | |
| 1 | 2 | 4 | 4 | 2 | 3 | 16 | SAM domain (Sterile alpha motif) | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | linker histone H1 and H5 family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal protein L7/L12 C-terminal domain | |
| 8 | 5 | 1 | 1 | 6 | 2 | 23 | Pectate lyase | |
| 1 | 1 | 2 | 2 | 2 | 8 | ribonuclease | ||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Urease, gamma subunit | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | CoA-ligase | |
| 19 | 18 | 25 | 31 | 20 | 11 | 124 | Phosphopantetheine attachment site | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | Formyl transferase | |
| 10 | 9 | 7 | 10 | 9 | 8 | 53 | Metallopeptidase family M24 | |
| 13 | 12 | 11 | 2 | 15 | 15 | 68 | Leucine Rich Repeat | |
| 49 | 39 | 29 | 13 | 52 | 31 | 213 | alpha/beta hydrolase fold | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | RNA polymerase Rpb2, domain 6 | |
| 3 | 4 | 4 | 4 | 4 | 4 | 23 | PB1 domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Staphylococcal nuclease homologue | |
| 12 | 12 | 12 | 12 | 11 | 12 | 71 | Rab-GTPase-TBC domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Tudor domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | WH1 domain | |
| 4 | 4 | 4 | 5 | 5 | 3 | 25 | Zinc finger, ZZ type | |
| 3 | 3 | 2 | 3 | 3 | 3 | 17 | HRDC domain | |
| 9 | 10 | 8 | 8 | 10 | 10 | 55 | CBS domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L13 | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Ribosomal protein L4/L1 family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Clp protease | |
| 2 | 2 | 4 | 3 | 2 | 3 | 16 | S1 RNA binding domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | HIUase/Transthyretin family | |
| 5 | 7 | 4 | 4 | 5 | 4 | 29 | AhpC/TSA family | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | tRNA synthetases class I (W and Y) | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | UvrD/REP helicase N-terminal domain | |
| 5 | 6 | 4 | 9 | 6 | 6 | 36 | Rhodanese-like domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Universal stress protein family | |
| 52 | 51 | 35 | 29 | 49 | 28 | 244 | Acetyltransferase (GNAT) family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | SecE/Sec61-gamma subunits of protein translocation complex | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | C-terminal regulatory domain of Threonine dehydratase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | AIR synthase related protein, N-terminal domain | |
| 8 | 8 | 8 | 7 | 9 | 8 | 48 | tRNA synthetase class II core domain (G, H, P, S and T) | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | SpoU rRNA Methylase family | |
| 1 | 1 | Phage integrase family | ||||||
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Tetrapyrrole (Corrin/Porphyrin) Methylases | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Glycosyl transferase family, a/b domain | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | PDZ domain | |
| 10 | 7 | 4 | 4 | 7 | 6 | 38 | Class II Aldolase and Adducin N-terminal domain | |
| 4 | 4 | 3 | 4 | 4 | 4 | 23 | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | |
| 5 | 5 | 5 | 5 | 5 | 5 | 30 | Fes/CIP4, and EFC/F-BAR homology domain | |
| 4 | 4 | 5 | 3 | 5 | 6 | 27 | IQ calmodulin-binding motif | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Phosphoinositide 3-kinase family, accessory domain (PIK domain) | |
| 6 | 5 | 6 | 4 | 5 | 5 | 31 | Phospholipase D Active site motif | |
| 1 | 1 | 1 | 4 | 1 | 1 | 9 | Regulator of G protein signaling domain | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | GTPase-activator protein for Ras-like GTPase | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | RasGEF domain | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | RasGEF N-terminal motif | |
| 8 | 9 | 8 | 8 | 8 | 8 | 49 | RhoGAP domain | |
| 6 | 6 | 6 | 6 | 6 | 6 | 36 | RhoGEF domain | |
| 3 | 5 | 2 | 5 | 3 | 3 | 21 | SPRY domain | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | RNA polymerase Rpb1, domain 2 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Guanylate kinase | |
| 5 | 4 | 4 | 3 | 3 | 4 | 23 | Gelsolin repeat | |
| 11 | 8 | 8 | 7 | 8 | 11 | 53 | UBA/TS-N domain | |
| 18 | 17 | 18 | 12 | 18 | 16 | 99 | PHD-finger | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | GGL domain | |
| 5 | 5 | 5 | 5 | 5 | 4 | 29 | HECT-domain (ubiquitin-transferase) | |
| 1 | 1 | 3 | 1 | 1 | 3 | 10 | Helix-hairpin-helix motif | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | MSP (Major sperm protein) domain | |
| 4 | 6 | 6 | 2 | 9 | 6 | 33 | Ribonuclease III domain | |
| 2 | 2 | 2 | 5 | 2 | 2 | 15 | Region in Clathrin and VPS | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | RanBP1 domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | PPIC-type PPIASE domain | |
| 1 | 1 | 1 | 1 | 2 | 1 | 7 | Zn-finger in Ran binding protein and others | |
| 17 | 20 | 15 | 8 | 23 | 14 | 97 | Zinc finger C-x8-C-x5-C-x3-H type (and similar) | |
| 3 | 3 | 3 | 4 | 2 | 2 | 17 | Poly(ADP-ribose) polymerase catalytic domain | |
| 2 | 1 | 1 | 2 | 1 | 2 | 9 | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | |
| 77 | 93 | 42 | 23 | 98 | 68 | 401 | F-box domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Elongation factor 1 gamma, conserved domain | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | Calpain family cysteine protease | |
| 2 | 2 | 2 | 3 | 1 | 2 | 12 | Copper fist DNA binding domain | |
| 5 | 6 | 6 | 5 | 5 | 5 | 32 | CRAL/TRIO domain | |
| 16 | 17 | 10 | 50 | 22 | 13 | 128 | BTB/POZ domain | |
| 2 | 2 | 2 | 2 | 1 | 1 | 10 | Ricin-type beta-trefoil lectin domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Inhibitor of Apoptosis domain | |
| 3 | 4 | 4 | 4 | 4 | 3 | 22 | Voltage gated chloride channel | |
| 2 | 4 | 2 | 3 | 4 | 1 | 16 | Caspase domain | |
| 15 | 13 | 11 | 3 | 15 | 13 | 70 | GDSL-like Lipase/Acylhydrolase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Poly-adenylate binding protein, unique domain | |
| 1 | 1 | 1 | 3 | POLO box duplicated region | ||||
| 28 | 24 | 15 | 18 | 21 | 14 | 120 | ABC transporter transmembrane region | |
| 9 | 9 | 5 | 7 | 9 | 5 | 44 | FAD binding domain | |
| 9 | 10 | 6 | 7 | 10 | 3 | 45 | Condensation domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | S-adenosyl-L-homocysteine hydrolase, NAD binding domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | HAMP domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | ribosomal L5P family C-terminus | |
| 6 | 5 | 5 | 6 | 5 | 7 | 34 | Insulinase (Peptidase family M16) | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | Dehydrogenase E1 component | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Lumazine binding domain | |
| 6 | 6 | 6 | 6 | 6 | 6 | 36 | Elongation factor G C-terminus | |
| 1 | 1 | RNA dependent RNA polymerase | ||||||
| 4 | 4 | 5 | 4 | 5 | 4 | 26 | HMGL-like | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | DnaJ central domain | |
| 3 | 1 | 3 | 2 | 3 | 2 | 14 | Starch binding domain | |
| 3 | 2 | 2 | 3 | 2 | 2 | 14 | Ribosomal protein L1p/L10e family | |
| 10 | 9 | 6 | 10 | 9 | 8 | 52 | Cation transporting ATPase, C-terminus | |
| 12 | 9 | 8 | 8 | 10 | 6 | 53 | Cation transporter/ATPase, N-terminus | |
| 2 | 1 | 1 | 1 | 2 | 1 | 8 | dUTPase | |
| 6 | 5 | 5 | 4 | 4 | 4 | 28 | Aconitase C-terminal domain | |
| 4 | 4 | 3 | 3 | 4 | 3 | 21 | Amino acid kinase family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | N-(5'phosphoribosyl)anthranilate (PRA) isomerase | |
| 22 | 24 | 19 | 21 | 16 | 9 | 111 | Acyl transferase domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Urease beta subunit | |
| 12 | 7 | 3 | 4 | 6 | 5 | 37 | Dihydrodipicolinate synthetase family | |
| 40 | 34 | 31 | 17 | 36 | 29 | 187 | haloacid dehalogenase-like hydrolase | |
| 9 | 5 | 4 | 4 | 9 | 2 | 33 | Glycosyl hydrolases family 2 | |
| 12 | 18 | 6 | 8 | 18 | 13 | 75 | Glycosyl hydrolases family 18 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Proliferating cell nuclear antigen, N-terminal domain | |
| 1 | 1 | Translation initiation factor IF-3, C-terminal domain | ||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Acylphosphatase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Adenylosuccinate synthetase | |
| 3 | 3 | 2 | 1 | 3 | 1 | 13 | Asparaginase, N-terminal | |
| 1 | 3 | 1 | 2 | 1 | 2 | 10 | Peptidase S24-like | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | Inorganic pyrophosphatase | |
| 8 | 7 | 12 | 17 | 8 | 8 | 60 | Glycosyl hydrolases family 16 | |
| 2 | 3 | 4 | 4 | 3 | 1 | 17 | Glycosyl hydrolases family 15 | |
| 5 | 8 | 3 | 6 | 9 | 4 | 35 | NADH:flavin oxidoreductase / NADH oxidase family | |
| 2 | 2 | 2 | 1 | 3 | 3 | 13 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | |
| 4 | 3 | 3 | 3 | 3 | 2 | 18 | Glycosyl hydrolase family 20, catalytic domain | |
| 4 | 4 | 4 | 5 | 4 | 6 | 27 | HhH-GPD superfamily base excision DNA repair protein | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | AIR carboxylase | |
| 27 | 31 | 24 | 23 | 31 | 12 | 148 | GMC oxidoreductase | |
| 2 | 2 | 3 | 3 | 3 | 2 | 15 | Asparagine synthase | |
| 10 | 10 | 14 | 7 | 8 | 9 | 58 | Fungal cellulose binding domain | |
| 6 | 6 | 6 | 6 | 6 | 6 | 36 | Septin | |
| 1 | 1 | 1 | 1 | 2 | 1 | 7 | EF-1 guanine nucleotide exchange domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Homoserine dehydrogenase | |
| 4 | 1 | 1 | 2 | 2 | 2 | 12 | Flavin-binding monooxygenase-like | |
| 1 | 1 | LPXTG cell wall anchor motif | ||||||
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | tRNA synthetases class I (E and Q), catalytic domain | |
| 2 | 3 | 2 | 1 | 2 | 1 | 11 | tRNA synthetases class I (R) | |
| 4 | 5 | 4 | 4 | 4 | 4 | 25 | XPG N-terminal domain | |
| 18 | 10 | 12 | 9 | 12 | 6 | 67 | Metallo-beta-lactamase superfamily | |
| 3 | 2 | 1 | 2 | 2 | 10 | F5/8 type C domain | ||
| 2 | 3 | 2 | 2 | 2 | 3 | 14 | Choline/Carnitine o-acyltransferase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Putative esterase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ferrochelatase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Arginosuccinate synthase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Electron transfer flavoprotein FAD-binding domain | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | RNB domain | |
| 7 | 7 | 4 | 4 | 6 | 4 | 32 | Dioxygenase | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | CNH domain | |
| 1 | 1 | 2 | 2 | 1 | 1 | 8 | Diacylglycerol kinase catalytic domain | |
| 9 | 10 | 6 | 7 | 7 | 7 | 46 | Dual specificity phosphatase, catalytic domain | |
| 3 | 3 | 3 | 3 | 2 | 3 | 17 | P21-Rho-binding domain | |
| 12 | 14 | 14 | 13 | 13 | 11 | 77 | PX domain | |
| 2 | 3 | 3 | 2 | 3 | 3 | 16 | Ras association (RalGDS/AF-6) domain | |
| 5 | 6 | 5 | 6 | 6 | 6 | 34 | UBX domain | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | VHS domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Phosphoinositide 3-kinase C2 | |
| 2 | 3 | 3 | 2 | 2 | 2 | 14 | DAHP synthetase I family | |
| 10 | 9 | 7 | 8 | 9 | 7 | 50 | Carbon-nitrogen hydrolase | |
| 2 | 2 | 2 | 1 | 2 | 1 | 10 | N-acetyltransferase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Prephenate dehydratase | |
| 2 | 2 | PKD domain | ||||||
| 4 | 4 | 4 | 3 | 4 | 4 | 23 | Syntaxin | |
| 5 | 5 | 5 | 4 | 5 | 5 | 29 | Pumilio-family RNA binding repeat | |
| 6 | 8 | 7 | 6 | 6 | 7 | 40 | Histone-like transcription factor (CBF/NF-Y) and archaeal histone | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Pterin binding enzyme | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | ER lumen protein retaining receptor | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Glycoprotease family | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | Histidinol dehydrogenase | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | impB/mucB/samB family | |
| 1 | 1 | 1 | 1 | 1 | 5 | |||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal L15 | |
| 1 | 1 | 1 | 4 | 1 | 1 | 9 | Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A | |
| 1 | 1 | 1 | 1 | 1 | 5 | Ribosomal L28 family | ||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal L29 protein | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal L39 protein | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal S17 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribulose-phosphate 3 epimerase family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Translationally controlled tumour protein | |
| 5 | 5 | 3 | 6 | 4 | 3 | 26 | Glycosyl hydrolase family 7 | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | RNA pseudouridylate synthase | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Histone deacetylase domain | |
| 11 | 8 | 4 | 9 | 8 | 4 | 44 | POT family | |
| 1 | 1 | 2 | 1 | 1 | 1 | 7 | PWWP domain | |
| 20 | 24 | 17 | 26 | 24 | 12 | 123 | SET domain | |
| 10 | 8 | 6 | 7 | 12 | 6 | 49 | Isochorismatase family | |
| 3 | 3 | 3 | 3 | 4 | 3 | 19 | Permease family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast | |
| 5 | 5 | 4 | 5 | 7 | 5 | 31 | XPG I-region | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Acetokinase family | |
| 3 | 2 | 1 | 3 | 3 | 1 | 13 | DNA photolyase | |
| 1 | 1 | 1 | 1 | 1 | 5 | NlpC/P60 family | ||
| 1 | 1 | 1 | 3 | Nitroreductase family | ||||
| 5 | 2 | 1 | 2 | 4 | 1 | 15 | Sulfatase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | 6,7-dimethyl-8-ribityllumazine synthase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal protein S16 | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Acyl CoA binding protein | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Cullin family | |
| 11 | 11 | 10 | 5 | 9 | 8 | 54 | FAD binding domain | |
| 10 | 10 | 12 | 23 | 24 | 6 | 85 | O-methyltransferase domain | |
| 3 | 3 | 3 | 3 | 5 | 5 | 22 | EamA-like transporter family | |
| 2 | 2 | 2 | 2 | 2 | 10 | |||
| 8 | 8 | 8 | 8 | 8 | 8 | 48 | ThiF family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal family S4e | |
| 11 | 9 | 3 | 5 | 8 | 5 | 41 | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily | |
| 5 | 6 | 3 | 4 | 5 | 3 | 26 | Ammonium Transporter Family | |
| 6 | 5 | 4 | 6 | 6 | 4 | 31 | Sulfate permease family | |
| 1 | 1 | 1 | 2 | 1 | 1 | 7 | MATH domain | |
| 4 | 2 | 1 | 2 | 2 | 2 | 13 | Dehydratase family | |
| 2 | 1 | 1 | 1 | 1 | 1 | 7 | Transaldolase/Fructose-6-phosphate aldolase | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Mechanosensitive ion channel | |
| 1 | 1 | 1 | 2 | 1 | 1 | 7 | GTP cyclohydrolase II | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | 3,4-dihydroxy-2-butanone 4-phosphate synthase | |
| 4 | 4 | 3 | 4 | 4 | 4 | 23 | Adaptor complexes medium subunit family | |
| 6 | 6 | 5 | 6 | 7 | 5 | 35 | Exonuclease | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Dipeptidyl peptidase IV (DPP IV) N-terminal region | |
| 2 | 5 | 4 | 2 | 13 | NB-ARC domain | |||
| 25 | 13 | 10 | 12 | 13 | 7 | 80 | Glycosyl hydrolase family 3 N terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal protein L44 | |
| 1 | 1 | Sodium:sulfate symporter transmembrane region | ||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | DNA-dependent RNA polymerase | |
| 1 | 2 | 2 | 1 | 2 | 1 | 9 | FAD binding domain in molybdopterin dehydrogenase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Glycosyl transferase family 4 | |
| 3 | 1 | 2 | 2 | 2 | 1 | 11 | HCO3- transporter family | |
| 2 | 3 | 2 | 2 | 2 | 2 | 13 | Nucleosome assembly protein (NAP) | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Synaptobrevin | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | GMP synthase C terminal domain | |
| 1 | 1 | 1 | 1 | 1 | 5 | Phage lysozyme | ||
| 6 | 7 | 5 | 4 | 5 | 2 | 29 | Adenosine/AMP deaminase | |
| 11 | 7 | 8 | 5 | 10 | 7 | 48 | Oxidoreductase FAD-binding domain | |
| 2 | 2 | 2 | 6 | 4 | 2 | 18 | Thioesterase domain | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Histidine biosynthesis protein | |
| 3 | 3 | 3 | 3 | 3 | 3 | 18 | Glycosyltransferase family 20 | |
| 1 | 1 | 2 | UDP-glucose/GDP-mannose dehydrogenase family, central domain | |||||
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Carbamoyl-phosphate synthase small chain, CPSase domain | |
| 4 | 2 | 2 | 3 | 3 | 14 | PAS fold | ||
| 2 | 3 | 2 | 2 | 2 | 2 | 13 | Probable molybdopterin binding domain | |
| 4 | 4 | 4 | 4 | 4 | 4 | 24 | Sec1 family | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | GDP dissociation inhibitor | |
| 7 | 7 | 7 | 7 | 9 | 6 | 43 | Sodium/hydrogen exchanger family | |
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | RNA polymerase Rpb3/RpoA insert domain | |
| 5 | 5 | 5 | 4 | 4 | 5 | 28 | Initiation factor 2 subunit family | |
| 1 | 1 | PQQ enzyme repeat | ||||||
| 2 | 2 | 2 | 2 | 2 | 2 | 12 | Electron transfer flavoprotein domain | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Uricase | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal S3Ae family | |
| 1 | 1 | 1 | 1 | 1 | 1 | 6 | Ribosomal L27 protein | |
| 1 | 1 | 1 | 1 | 1 | 1 |
