LOCUS       scaffold_551           16441 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  .
ACCESSION   scaffold_551
VERSION     scaffold_551
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2025-04-15 22:58:10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16441
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16441
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[12678:14938]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12679..14938
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..16441
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16441
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             281..2179
                     /locus_tag="10071"
                     /transl_table=1
                     /translation="YELPSYVNAAFLYPVTASNGSSIVVCGHDQGVSILWRGGRPLKPF
                     KQPERSPPKPKKSNSSAILLLDSDDDQPPPPPKPKSAPTQAPEFEDEEEEFDSRRPYPP
                     IIQQLDLPLGIAVLHASYPELPSRDATNFQYLPKLLQEKLVVAMTCADNTVRLLMLPLD
                     PPPHQLKAKAKMAENVLKAFPGNGFWGEDVLTLGGSYKHRTLPKGVSLALAPQVVQESI
                     EEEEEDDVHQPSKPFRRRSSSAKGPASSTEIRGSGLWDLLIASHSQDVTGLLLIHRVPV
                     SNDKPTIDLGSNDHDLIWRTEHLHGPAVTVQLYVPSQSCEKPVPRLLVAEASGPVRILD
                     AYTEQNPDRGSWRLTLYPNMETTQNGVPSVRAIIDAKWILAGRAIAVTFSDGEWGVWHL
                     GPKSTICGGMPSKFTLNGWISDSLEAASDTSKKSTGRFPSKLAPMTPGTRKQKQDTLFS
                     EASSTPRPKVPSTSGGIVVYHRSRPSSGKELDEVVTIWHGNRMMIIPSIRGYWHTRVEG
                     GGSLFASDVSSQSRSFSNAGLPGGLGHCVTLGFDGKSGSRQPEIIVISGGCLTILTRPL
                     IEEKTLPLVIRDQQLLKRGELGLDGVERILSDMPDNSIDSMNGVVPLERRVGFGPS"
     CDS             complement(5512..6063)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="10072"
                     /sec_met_domain="p450 (E-value: 8e-29, bitscore: 89.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGVDHYKVFRAWWDPVMQDMAGGVAPPSFTRDVILQSNGKYATNS
                     DEAMYLATSIVAAGSDNVRMAHNVFMMAAVCHPEVMAKARTEIDSVCGPDANRLPNLAD
                     MESLPYISAILKECLRWRPVVPLIPQHHSTKEIHFDGFVFPAGTDFVINSLAVCGEVDD
                     PADFKPERWGNREMNITDGL"
     CDS             join(8033..8212,8302..8798,8852..9257)
                     /locus_tag="10073"
                     /transl_table=1
                     /translation="MPGMSPLPGPSEGDVDIGYKLEIGTTVTFIAAAIVVGLRFVARML
                     YARLGWDDYMMMFATVQALVATILDFVAIHWGLGRHTFFLDPQQRVQQQYYSLLAQVFC
                     IHALTFAKISICLQYARVIRGSQKSLLRWTCYTIAILVFCVNGMVTIVFYAHCIPAEKT
                     WNSSIQGTCWNFQSFGAFLLLQGSFSAATDYILCILPIFLFKDLQIGMKSKIILCTLMG
                     LGLITGIFATIHTAETNAGLKSPVQDTPYDSIMGLTWAGMERNIAIMIGSIPSLRPLVT
                     PFINLTTRTFWGSIFSTKKSQTGTYELGSKGSKISSQGHFDLDRDGMGGRKAFLGQNGA
                     KYSQTSTTRSNISQERILPM"
     CDS             complement(9703..10554)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 76.1; E-value:
                     4.9e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="10074"
                     /transl_table=1
                     /translation="MASSAPASTQEGLAAFASVISVYEHRVGHACRAVASHLPPLLKSF
                     PAVGGTVLDNACGTGAATQEFLKVYPSAEVSAADVVPPMVQSFKAIIAADPALAAQVKD
                     LRLENGENLTYADNTFDAVLTNFGIFFFPDPVAGAKQIYRTLKPGGTAVVTLWKTFGFK
                     PILWEAQERVKPANPLTELPLMEPWCDPKKLEKVLTDGGFGSVEFSVVKEGMWGKDKAD
                     FVTVLLENFGAMVSRNWTDEEKAKLAPVTSQVVNEMQDKFCITDGEKVGCMMEASAAVC
                     TK"
     CDS             join(12679..12972,13042..13414,13422..14938)
                     /NRPS_PKS="Domain: AMP-binding (19-353). E-value: 1.6e-21.
                     Score: 68.2. Matches aSDomain:
                     nrpspksdomains_10075_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (649-722). E-value: 7.7e-10.
                     Score: 31.1. Matches aSDomain:
                     nrpspksdomains_10075_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 54.3;
                     E-value: 1.3e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="10075"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-19, bitscore:
                     58.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.2e-11, bitscore:
                     31.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSGINTSPDAISLLPAVLDEIAANEPTRIFVSVPRSSDILEGFRD
                     IEYGTCAKAVDKFALWLREQVGQESEPKTIMYFGPLDIRYLPVLLGAAKAGHIGFLSSH
                     RNSIEAHQSIAEKAGCETVLVPDDAPAMLSQILQARPMKQIHTPAVEYFFQDLDQVEHV
                     PFIRTWEEAKNSPFCVLHTSGSTGIPKPVFVTHGTFACIDAHQLIPKLGGKPTLVSFLK
                     DILSRCHYFMLHPFTFTIGHNVFAGVISVIPPPEPLTADLANQVFTHGNLDGALLAPSL
                     IVDCYNNNEYCVNMIQRLKFLSYVGGSLPAEVGNSLTTRTKLMTLMGSCETALHPLEIN
                     DEQTDWEYLTISKFLGHSFHKDRDGYSELIIRRAPEYEVFQGVFSTFPEKQEFASGDLF
                     EQHPSRTESWVFRARTDDIIAFTTAEKLNPVTMESVISTNPKIKSALIGGQGKFQASLL
                     LEPYVYPKSKVEEEQYIKDIWPSVLRANRDCPAHGRIMKGFVMITDPKKPIPRAGKGTV
                     QRHAALQLYAKEFEALYKKMQPSANIESKLPEQRSQSIMPARVNGVNDIDARIEKALVK
                     LLPAAMEEAIRKTLSQMLLGLNGPLPVQQSVEKPTPLLTNGHTYSTTNGITSPVTNGVS
                     KEVGEPTASTPPKDVRQIIYDELAENLDMTDVTDDIDLFDHGLDSLQVQSLVTTLNAYL
                     IRLKPGVELLQAKQVYDKPTVREIMAMVEWSVV"
     aSDomain        join(12736..12972,13042..13414,13422..13813)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_10075_AMP-binding.1"
                     /evalue="1.60E-21"
                     /label="10075_AMP-binding.1"
                     /locus_tag="10075"
                     /protein_end="353"
                     /protein_start="19"
                     /score="68.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EIAANEPTRIFVSVPRSSDILEGFRDIEYGTCAKAVDKFALWLRE
                     QVGQESEPKTIMYFGPLDIRYLPVLLGAAKAGHIGFLSSHRNSIEAHQSIAEKAGCETV
                     LVPDDAPAMLSQILQARPMKQIHTPAVEYFFQDLDQVEHVPFIRTWEEAKNSPFCVLHT
                     SGSTGIPKPVFVTHGTFACIDAHQLIPKLGGKPTLVSFLKDILSRCHYFMLHPFTFTIG
                     HNVFAGVISVIPPPEPLTADLANQVFTHGNLDGALLAPSLIVDCYNNNEYCVNMIQRLK
                     FLSYVGGSLPAEVGNSLTTRTKLMTLMGSCETALHPLEINDEQTDWEYLTISK"
     aSModule        12736..14920
                     /complete
                     /domains="nrpspksdomains_10075_AMP-binding.1"
                     /domains="nrpspksdomains_10075_PP-binding.1"
                     /locus_tags="10075"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       13279..13335
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_10075_0001"
                     /evalue="7.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="10075"
                     /protein_end="196"
                     /protein_start="177"
                     /score="18.7"
                     /tool="antismash"
                     /translation="CVLHTSGSTGIPKPVFVTH"
     aSDomain        14702..14920
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_10075_PP-binding.1"
                     /evalue="7.70E-10"
                     /label="10075_PP-binding.1"
                     /locus_tag="10075"
                     /protein_end="722"
                     /protein_start="649"
                     /score="31.1"
                     /tool="antismash"
                     /translation="VRQIIYDELAENLDMTDVTDDIDLFDHGLDSLQVQSLVTTLNAYL
                     IRLKPGVELLQAKQVYDKPTVREIMAMV"
     CDS             join(15567..15752,15808..16012,16125..16441)
                     /NRPS_PKS="Domain: Aminotran_1_2 (88-218). E-value:
                     1.2e-23. Score: 75.7. Matches aSDomain:
                     nrpspksdomains_10076_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 100.2; E-value: 2e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="10076"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-24, bitscore:
                     75.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSGLSSRGHLNLRQIIAKIPKSILEPTPNPDAIDLSMAENHLIRE
                     EILKIVKSSIVGDLHSKHLDWPKGFCGDSDLLGHLTDIFNKRFHPFSTVKQEHVTVTSG
                     ASACLDAVLYTVCDPGDGVLVPTPYWGGYDAFLTSHSGVKPVSVDVPDLEDSLGPALID
                     ALEDAYESSEYRIRALVLCNPHNPLGRCYSKKMLEDCARFCQSRGIHLISDEVFALSSF
                     CRTNHYGKETYWC"
     aSDomain        join(15886..16012,16125..16387)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_10076_Aminotran_1_2.1"
                     /evalue="1.20E-23"
                     /label="10076_Aminotran_1_2.1"
                     /locus_tag="10076"
                     /protein_end="218"
                     /protein_start="88"
                     /score="75.7"
                     /tool="antismash"
                     /translation="HPFSTVKQEHVTVTSGASACLDAVLYTVCDPGDGVLVPTPYWGGY
                     DAFLTSHSGVKPVSVDVPDLEDSLGPALIDALEDAYESSEYRIRALVLCNPHNPLGRCY
                     SKKMLEDCARFCQSRGIHLISDEVFA"
ORIGIN
        1 attcttataa agagtattct tatatccagt ttttactgta gtacctgtgg ttttgccgaa
       61 taagggtcta ccggccccgc aaggctgagc cgcgtcaact tattattcaa ccgcgtctgc
      121 agcttcaaat ctggacagga agatcaaagt ggtttcagcc tcgcggacag ctcatcgagg
      181 catgaagcca agggtgacct cggtcgatgg actgctcaag ctcaggttac taactcaatt
      241 ttcaaaatgg gcttgttcaa atgctgacac tggccacagg tatgagctac cctcttacgt
      301 caatgcagcc ttcctctacc ccgttactgc atccaatggc tctagcatag tagtgtgtgg
      361 tcatgaccaa ggagtttcta tcctgtggcg gggaggtaga cctctcaagc cgttcaagca
      421 gcctgaaaga agtccaccca aacctaagaa aagcaatagc tcggcgatat tattactcga
      481 ttcagatgat gaccaaccac caccacctcc gaaaccgaag agcgctccca cacaggcccc
      541 agaatttgaa gatgaagagg aagagtttga ttcgcgaagg ccgtatccac ccatcataca
      601 acagcttgac cttcccctcg ggattgcggt tctgcatgca tcgtatcctg aattaccctc
      661 aagagacgct accaacttcc aatacctgcc aaaactgctg caagaaaagc tcgttgtagc
      721 aatgacatgt gccgataata ctgtcagact gctgatgcta cctttagacc ctcctccgca
      781 tcagctaaaa gcaaaagcta aaatggccga aaacgtcttg aaggcctttc ctggcaatgg
      841 cttttgggga gaagatgtac ttacactcgg tggaagctat aagcatcgaa ctctacccaa
      901 aggtgtatct cttgctctag ctccccaggt cgtccaagaa agcatcgagg aagaggagga
      961 agacgatgtc caccagccaa gcaagccgtt tcgaagacgc tcttcgtcag cgaagggtcc
     1021 agcgagttcc acagaaattc ggggtagcgg actatgggac ctgcttatag catcgcactc
     1081 tcaggacgtc acgggacttc ttctgataca tcgtgtcccc gtctcgaatg ataagccgac
     1141 cattgacctt ggctcgaacg atcacgatct tatatggagg acagagcatt tacatggccc
     1201 tgccgttaca gttcagctgt atgtaccatc acagtcatgc gagaagccag ttccacgtct
     1261 tctggttgca gaagctagcg gtccggtccg aatactcgac gcctacacag agcaaaatcc
     1321 agatcgggga tcctggcggc tgacactcta tccaaatatg gagactactc agaacggcgt
     1381 accgagtgta agagcgataa tagatgcaaa atggatactc gcaggtagag caatcgctgt
     1441 gacattttcg gatggcgaat ggggagtatg gcatctcgga ccaaaaagca ccatatgtgg
     1501 cggaatgcca agcaagttca ctcttaatgg ctggataagt gattctttgg aagcggcaag
     1561 tgacacttca aaaaagagca caggtagatt cccatcaaag ctcgcaccca tgactccagg
     1621 cacccgaaag cagaagcaag acacgctctt ttcagaggct agcagtacgc cacgcccaaa
     1681 agtcccgtca acgtctggcg gaatagtagt ctatcaccgt agcagaccat ccagtggcaa
     1741 agagcttgac gaagtggtaa ctatctggca tgggaatcgg atgatgataa tccccagtat
     1801 tcgagggtac tggcacacgc gcgtcgaagg tggaggaagc ttgttcgcta gcgatgttag
     1861 cagccagtca cgaagcttca gcaatgctgg gctccctggt ggccttggac actgcgtcac
     1921 tttgggcttt gacggaaaat ccggatccag acaaccggag attattgtaa taagcggagg
     1981 atgccttaca atacttaccc ggccgctaat agaggagaag acactgccat tggtcattcg
     2041 agatcaacaa ctgctcaaac gtggagaact tggactcgat ggtgtggaga ggattctttc
     2101 ggacatgcca gacaactcaa tagactctat gaatggagtt gttccgttag agaggagagt
     2161 aggatttggc ccttcctgat gagttacaat tcaactcaat tgactgacgt ttaccatgta
     2221 cgctccctcg acaacagtta ctccagttat atttcataga tacccaatgc agttattcct
     2281 ccatcccttt ccttcttgtc attattcccc ctctacaaac tttcgctcac tcgcccggtc
     2341 cacaattcgc gcgacaaggt ggagccccag aaaaagcctc atttctcctg ctctgtattc
     2401 gctgcgatat attaaaaatc acccggtcat agactccctc gggagtcacc cttccaccac
     2461 tttcttgtgt aactggtctt ccagtatcga tgagctagct gtgcggaagg gaagatggtt
     2521 ggtgtgcaag ggggtttcat ctcaaagtac cctttttgcc ggagcacctt acaggccttc
     2581 gggctgtggg tgtgaagatg gcgtaggttg acttggcttc caccttcagg gcatacagtg
     2641 agctttctca aggtttactg cggtgaagct gggttaagag acttcccgta catattccgt
     2701 gtttttacgc aaaagaatgg acgatagtaa cataggtcaa tatcgtggga aatatcctat
     2761 gatgtattgt tgaggaagtc tttcaggcct ggcggttttg gtccaatgtt gggagtgaag
     2821 atcgctaaag tgcaacgtga agcaaacaag gtgccaaagt tgcgtatcaa tcatatccca
     2881 agccctctct ccaacctaag aaagctccgc tactttgccc cggaattctt tttcggagga
     2941 aactccgccg tggaaaaggc ttcagcatat ttcagaaatg tcaagtcgaa atatcaaagt
     3001 cgactgtttc aaaaacccac gagtatatat aaattgttca aatgttacta gatgttttag
     3061 gctgtaactt taccagtctc gctgggaagc cccttctgta atatcagagt aacatcattc
     3121 ccacggacgc cttggcacaa ttttcccgat ttttcataat aaaatgcccc atataagtgt
     3181 gatgtctcga tgttcaacaa tgtagacctt taatggtttc tgatcacaca gaatgagccg
     3241 acagcgtgtc cgaacggggt tggcgaaaat agtgggagcg agcagaagcg aggagagggg
     3301 ttaagagaag agatcttgga cgcattgtga ggttctttgg gtcgctcgtt tggagaggaa
     3361 gaagctgctt gtgatttctg gagactttgg aagaaaaaag gaatacggaa ttcgattttg
     3421 acaaccgatg tcgaaactcg ttgcttttcc tagccccagc tcggatacgg aggtttgctg
     3481 actggatgta ggaggctttg gacggcgccg cacctgtagg taccatggaa attctataaa
     3541 tccggaccgt gccgaagtac atgtatgtaa tcatcatctt gcatacggcc tggcgcttat
     3601 accgcacgca atcgcatgca tctttacctt gaagtttaat gttattgagg cgcccgggtc
     3661 gatcttcaag ttcataagta gtactaacct acctatcaac ttcagcccca agagaaagcg
     3721 atgcaagttt cggggatcgg gaaagggaaa gggaagatcg cgacacgtcc ccaaaacaag
     3781 ttgggatttg tttacatgac tcaagtggtt ttcgacttct ccgaactgcg ccattatcgc
     3841 agatatacta ggcaagtagt gatgcaatat gtcaaaattg tgggtcaaat acagtgtggt
     3901 caatagtccg tctagtccgg cggatgaccc gtctgtttga tattatctag tttgttcaaa
     3961 aattttaatt agtccgtcca gtctgtttaa ataatttaat taaattattc aaactgtcta
     4021 tagggctgat ttaaacaatt tgtttagtct gtttgattat attaattagc ccgtccaatc
     4081 tgttgattag tccgtttgat taatgcataa atatatatat ttttcatata ttcagcataa
     4141 tataataggg gtaggatcct taggggggtc ctcaggggga ttcttagggg gttgagtctt
     4201 caggggagtc cttagatggt tatggaggga gccctgaagg gagttctaga gggagccctg
     4261 gagtcttgaa gagattttta gagccctaga gagagcccta gaaagaggga tgcttctctt
     4321 tttatatcag ttttatataa ctagtcggat gcatccgttt gataaattat taattagtct
     4381 gtccaataga gctgtcaaat cagtccattt aattatatta agtaatccgt ccggtccgtc
     4441 tataaatatt aattaaatca gttaaatcac gctattaaat agtctatcca gtccgtccat
     4501 agggctatag atggactgga cggactattg accacactgg tcaaatattt gccggaacaa
     4561 aaggaaattt ttattgctac ttattgtgct aaaaaatctg tatggctgaa ttttatgagc
     4621 atttgtctgt atattccatc aatgagaaga tctttggatt ttagaaaaac atttcctctt
     4681 acatatatat aacttctcca gacttgcact aacctgtgat ccttcgctga ttaatgtatt
     4741 gccgtcttat ttttgtttaa ttttaatttt cttgtgttta cttattgcta aatttctatt
     4801 gttattaaaa aataattatt taataatgtt aaataaaatt ttatattaag ttaataatgg
     4861 ttttatattg aatttgggag ttatatatgt gtcgacgagg cttcggccgc tgataaactg
     4921 tctcgccaaa gcagaacagt tttccgtcag gtttgactcg aatgatgcgg gcgtaaaggt
     4981 taagttaaat atctttgaag atacgttgcg gctaacgctc cgcctcgatt ctgcgcaagc
     5041 ttctctatgc tggggatatt taaggatgaa ggaaagagga ggtgacgatg cgttgaaagt
     5101 cagcaatttc tctcatggca caagacatca ataacagcta ccagcgacgt gggactagac
     5161 atcgattacc ggcagccgca acagcagata tttgtatatg gttttatcaa tttacataat
     5221 gttttgcgtc taagctcgac cgtttaatgc attaacgagc tccttataag ccttactccg
     5281 aggcttcaga agcaccggaa atggctcctc aatagtatca tgtctcatac ggtagctatc
     5341 gagtgggcca ttctaagttt tctggttagc aagccagttt tgttgcgtgg aaggcaaggt
     5401 tgaacgtact ggaatgaagt caaaacagta tatcgatttc gcgaatgcca gatatagttc
     5461 ttggtgtgcg attttatacc caacgcatac cctccttcca ccgccaaact gtcacagacc
     5521 atcggtaatg ttcatctctc tattccccca cctttcaggc ttgaaatctg ctggatcatc
     5581 gacttctcca cagacggcca gcgagttgat gacgaagtct gttcctgccg ggaaaacgaa
     5641 cccatcgaag tggatctctt tggtggaatg atgttgcggg ataagcggca caacgggcct
     5701 ccaacgtaga cactctttta atatggcgga aatatatggc aaggactcca tatccgctaa
     5761 attagggagc cgatttgcat cagggccgca cacggaatcg atctctgtcc gcgccttggc
     5821 catcacttcc ggatggcaga cagcagccat catgaacaca ttgtgtgcca tgcgcacgtt
     5881 gtcgcttccg gcagcgacta ttgatgtagc taggtacatg gcttcatcac tgttggttgc
     5941 gtacttgcca tttgactgta gaattacgtc ccgggtgaat gaaggtggcg cgacaccgcc
     6001 ggccatatcc tgcattacag ggtcccacca agccctaaag actttgtaat gatcgacccc
     6061 catggaggac caaaacaagc gagaaggctg gaagatccct aggctgggaa agaagtcgaa
     6121 gatgctgctg ttgatgcttc ggatgaacca caatacggtg agctatggag tacgaatagc
     6181 tataattatg cctgtgccat tggtcgggtt ggtgaaggta gttgtgtagc agcgtggtgc
     6241 tttcggcttc ttgaatgccg gaataagtct tgagagcggt accactcagg agatgatgca
     6301 taagctggcg tccttctttc cagtctctgg ttttccgcag aacagttcgc ttattattgc
     6361 tgacaagagc accagcgacg ggaaaatcgg gccggtctcc tgtggaagcg caattctttg
     6421 aaatgatctc ctttaccaat ctgtcgctgt ttagtatcac ccaagtccgg ctgcccattt
     6481 gaaccgtggt catctcccca taggaagcca aggaatgcgc ctgcagaagt cagtcaacat
     6541 gtcaaagatc aaaatgggca agcactagag ttacgaaacc agcgaatttg acaggatcag
     6601 ttctagcttc acgcagcctt aggaggctgc caagaacagg aagatctcga gggcccggtg
     6661 gaagattgct cgtcctcctt aagatcttag atcctagcaa aaagaagatg taactgaagc
     6721 agatcgtaat ggaaaggacg atatagggca atagtactgc tttatggctg gaatggatga
     6781 ctagatcgat gtggctccgt tggagacgct ccagcacttg gactgatcgc agcgatgcag
     6841 cctcgtacat tgggaatatc cataaacctg gacttcccgc aacctgaagg accgaagaat
     6901 tgggcatttg ggatagaagg aatcaagagt tgaggaacaa ggtgaagagc tctgcaccga
     6961 gactcgcgag gtgttggttt agctggcttg gaagctgaaa tagagtcacg aaaaagattt
     7021 acagaggatg atctgggaga gcaggtgggt ctcgagagcg ggtatcgctc gagctgtggc
     7081 caacacacag cccggtctcg atggggcacc ggctgaagtc tattatattt gaaaaacgtc
     7141 tcgctgacga gatgtcactc gcgctcgagt tcgtggccat gatcgggcag agtaagacga
     7201 ttagagcttg aagccggggg ggataagtag taattcgaga tggcaggtgc ggaataatgc
     7261 ctgaaacaca cactcaggac atacctaaac agatacctag tatcttacgg taatcaatga
     7321 aggtatttat cactagcgga aacattatta gcttggtgtg tgaggcaggg gtgtatgagt
     7381 acttttagtc gcggcccgtg tggctgcggc ccgtgattcg tgtttctgat ccaactacag
     7441 taaaaactgg atataagaat acctcgcgta gcagaatttc tattcttata tccagtttat
     7501 tcttatatcg agactggaaa ttggtgtaaa atcactagtg tgtcttagaa aaattattct
     7561 tctatccaga ttattcttat aaagagtatt cttaatatcc agtttttact gtactacaaa
     7621 aatggatcct actgaggggc aggcagtgct aacaggacaa caagcagcta cgtatatcat
     7681 actatgttag actacatgca cacatgccat gccgcacgtt agaaccgtgc taatgtgctc
     7741 tgttgaagtc acatgggctt tcccctgaat tgagttgatc ggcagtatcc tccaacgtga
     7801 tatggcgtgg tatacttact gcccggcttg ctgctggccg gcaaggttga aagagaggct
     7861 ctcatcccag gtcccagtta tctccccccc tcatcttcgt aagctcttct tgctcaactc
     7921 gtcaagctct aagccaattg attgtttggc atatctcctt ttgttatgac agcagcatcg
     7981 ttcgactctt ctgcctctac atacgagaca ctctgtgtat ccctgagata agatgccggg
     8041 aatgtcccca ttaccgggac cgtctgaagg agacgttgac attggctaca agctggaaat
     8101 cggtacgacg gtcaccttta tcgcggcagc tatcgtggtt ggactgcgct ttgtcgcgcg
     8161 tatgctttac gcgcgtttgg gctgggacga ctatatgatg atgttcgcga cggtttgtgt
     8221 ttcctgagct acacggcgaa agaaatacat cgcaagtcgg gcgtagctgc tcactgcaga
     8281 ctgactcaat ctctactcta ggttcaagct ctcgtcgcaa ctatattgga ctttgttgcc
     8341 atccactggg gcctcggtcg gcacactttt ttcctggacc cgcagcagcg agtccagcag
     8401 cagtactatt cgctgctggc ccaagtcttc tgcatccacg ccctgacctt tgcaaaaatc
     8461 agcatctgtc tgcaatacgc acgtgtgatc cggggttcgc agaaaagttt gttgcgatgg
     8521 acttgttata cgatagccat cctcgtcttc tgcgtcaatg gcatggtgac cattgtcttc
     8581 tacgcccatt gcatcccagc tgagaagaca tggaactcgt caatccaggg gacttgctgg
     8641 aattttcaat cattcggagc cttcctatta cttcaaggat cattttctgc ggccacggac
     8701 tacatccttt gcatcctgcc gatattcctc ttcaaggacc tccagatcgg aatgaagagt
     8761 aagatcattc tctgcacact catgggcctc ggattaatgt aagcatactc ccattctcca
     8821 tctttgtatc gcaactctaa cgtcggtaaa gcaccgggat atttgcaacc atccacaccg
     8881 ccgaaaccaa cgccggtcta aagagccccg tgcaagacac cccctatgac tccattatgg
     8941 gcctaacgtg ggctggcatg gagcgcaaca tcgccatcat gatcggcagc atcccatccc
     9001 ttcgcccatt ggttactccg ttcattaatc tcacgaccag aactttctgg ggatcgattt
     9061 tcagcaccaa gaagtctcag actgggacct acgagctcgg aagcaaagga tccaagataa
     9121 gctcgcaagg tcactttgac ttggaccggg acggtatggg aggtagaaag gcctttttgg
     9181 ggcagaatgg ggccaagtat agccagactt cgacgacgag gtcgaacatc agccaggaga
     9241 ggattctgcc catgtagaac tatgaagata aatatcggca ggttgtttag attagagtga
     9301 tttctggatg ccacggcctg tgcgaccctc gcttagttat atacctgaga agtgcacgcc
     9361 tcagtcaatc ctagcgagct cgcgaaaata tgatttgctc ttggtctatc attccaattc
     9421 tttagagcga cgcatatgaa cagttctcgt gactgtcaag aagatctata cagcaagatc
     9481 ctaaaccaag tgcctctcac atgcagatgt tccttttcgt ctgtcaagac tcaagagtct
     9541 gtgaaatgag tgacagtagg acactgaacg cgctcgtaca gcttccgcac acggcacaat
     9601 tgcactcatg attgtttgta aatagtattg tatattgaaa gggatgaagg gcaatggtcg
     9661 ctgctacccc acagcgctaa agagttctat ctctagaaac gttcacttgg tgcaaacagc
     9721 agccgaagcc tccatcatac accccacctt ctccccatcc gtgatgcaga acttgtcctg
     9781 catctcattc acaacctgcg atgtgacggg cgccagcttc gccttctcct catccgtcca
     9841 gtttctcgaa accatagccc caaaattctc caacaacact gtcacgaagt ctgctttgtc
     9901 cttcccccac atgccctcct tgacgacgct gaactcgacg cttccaaatc cgccgtccgt
     9961 cagcactttc tccaacttct tggggtcgca ccacggctcc atcagcggca gctccgtcag
    10021 cggattcgca ggcttcacgc gctcctgcgc ttcccaaaga atcggcttga agccaaacgt
    10081 tttccagagc gtcaccaccg cggtgccgcc cggcttgagc gtgcggtaga tctgcttcgc
    10141 gcccgcaacg gggtccggaa agaagaagat gccaaagttg gttaggaccg cgtcgaacgt
    10201 attgtccgcg taggtgaggt tctcgccgtt ctcgagccgc aggtccttaa cctgagccgc
    10261 gagcgcggga tccgcggcga tgatggcctt gaaggactgc accatcggtg gcacgacgtc
    10321 ggcggcggag acctcggcgg atggatagac tttgaggaac tcttgggtgg ctgcaccggt
    10381 gccacaggcg ttgtccagga cggtaccgcc tacagcggga aaggacttga gcagcggagg
    10441 caggtgtgag gcgactgccc ggcaggcgtg gccaacgcgg tgttcgtaga ctgagatgac
    10501 agaagcaaag gcggcgaggc cctcctgggt actggcgggg gcggaagaag ccatgtcggg
    10561 tagcgtatct gttcgaggtg aggatgctaa gaaggagaca ggaagtaggc aggatcggtt
    10621 ggcttcttga acttgagaca gtggtcgttg atcactcgca ggcttatgta tacggtggcc
    10681 gtagattgtt gccctgagga gttgaggagc cggagaacga agagatcgcc gctgccggac
    10741 tttgaaaatg tgattgctgt gcccgttaac ccttgccctg cttctgtgtg actggaaatg
    10801 tatgtctcct aaatgcatgt gtattgaagg atctgtcatc tgagccccac ctgctctagc
    10861 taataatctg ataccattcg cgcaagcccc cgtacgagat agtgtctgtg ttgaggactt
    10921 ctacctagta ccgaatttgt ttattttgag aaaacactaa ccccaaatag gtaaaggttt
    10981 ttcgtcgaat tgttttgaca ttgttgtgat atcttttccc cccttaatct cgtcgctact
    11041 aatgacctcg ggacccctca ctcgttcctc gtacggcgca tagcgcctag cgtctctcta
    11101 gagcatcgca cggaggctga ggccgacacc cagcactcct tctaataact gcgatgcacc
    11161 tacagagcag agctaaaaca caggatacac gatggatgat cgaacacaaa agcaggtgcc
    11221 aacaccgatg cgaagctgcg gcacccgcag ccaaataact tgctatccga ttacatgcgt
    11281 gtcctacatg cgtgtccatc agcttgcgtt cagatcctgc ggcaccgacc ggctgcggcg
    11341 tattcaacag ctgaccggat cctggaaact ctacctactc tatctgatat tccccacagt
    11401 ggcttccgcc gtacgacatt tagcacgaaa aaatatatat tataatcctt gagatgtaaa
    11461 taattaggga tttcttgttc aattcttgaa agaataatcc cttttaaagt tatcctgaga
    11521 gatcctgctt aaaaaattag taagataaca gcctaaatta gtgtgatata gtgaagattt
    11581 ataatagagt ttcaaacgcg ctaaatatcg cgaaatgtca ctaacacctg gcagtttggg
    11641 tttgccctag cttatatttg tgggtgatta taatcctgga ttgtttactc gctttgtttg
    11701 gtgtgataaa aaaataacct ggaagtaaag ctttaccaaa tccctaataa ttacatgtag
    11761 ctaaaacccc tagtgtttaa gacaaaggct tttaaaatcg cataaaaatg agcggagttc
    11821 actacagcaa caacacagaa tctgcaggat ttaatagtac cctcgggaaa gcccgaattg
    11881 ataggtaggt gttagtgtag gggaaaatgc tgaattacag ccacattgaa cgccagctgc
    11941 tccgacgatt ctcccaaaac ccacggcacg gtaagtgaat ctatcacagc tcatcgttta
    12001 gcgtggaatg actagccttt ttatagtcat gtcgccgcgg cggaatgact tcgcagcgtg
    12061 acgtgctggt aatgccggca aatacgtcca caagcgggat agtggggact tttacacttt
    12121 cctgttgttg tttcagtaga ggtaatttaa tgtaatcgtt cggcaatctg tgagctagca
    12181 cagacctgag ataaggtagc gtcagctagc gcaacacttt gtatgtgctt ctgacggcac
    12241 aggtatcggc ccgcgaaaga atgccgaaga cttggaactg cttgtgtgcc acacggcgac
    12301 agccgaacgt tagatttacg tcagatcagc gacaggaccc gtttcaaatt gtattgtacg
    12361 cgtatatggc gtgtcacgta tcattaccgc tttggctagt ccagacgtat agaatgcaca
    12421 gtcgagcttg tatcgctagg tacataacta tggagcggag ctttcaagtg cagataacag
    12481 cgcaggtcct ccgtcttgct tcgaagatgc attgtcctcg ccagcagctt cacaaacatg
    12541 gagctcactc cagactttga tgtgccgcca aattgcggga agcgtttgta atagcatttt
    12601 gaatgcgaga agtagcttgt attctagata atgtggtggt gtggagttat atacatgttc
    12661 gcttaggtaa acaacactat gtctggaatc aacacatccc cagatgctat cagtttgctc
    12721 cccgctgttc tggatgagat tgcagcgaat gagcctactc ggatatttgt ctcagtgcca
    12781 aggagctcag acatcttaga aggatttaga gacattgagt atggaacgtg tgccaaagcc
    12841 gttgacaaat ttgcgctttg gttacgtgag caagttggac aggagtcgga accgaaaaca
    12901 ataatgtatt ttggaccctt ggatattcgg tatctaccgg tgctactggg tgctgcaaag
    12961 gctggacata ttgtaaacct gccatacgaa gactctctct ctctcttttt ctcttcatga
    13021 agttctaaca tcaggcggta gggattcctt agctctcatc gtaacagtat cgaggcccat
    13081 caatcaattg cagaaaaggc cggatgtgag acggtactgg ttccagatga tgcgccagca
    13141 atgttgagcc agatcttgca agccagacca atgaagcaga tacatacgcc agcagtggaa
    13201 tatttcttcc aggacttgga ccaagtcgag cacgttccct ttatacgcac gtgggaggaa
    13261 gcgaagaaca gccccttctg tgttctacat acatccggct cgacaggaat cccgaagccg
    13321 gtattcgtca ctcatgggac ttttgcttgc attgatgccc accagctaat accaaagctg
    13381 ggcggaaaac ctacactggt gagcttcctc aagggtaaaa gatattttat cacgctgcca
    13441 ttatttcatg ctgcatccct tcacattcac tatcggacac aatgtcttcg ccggagtaat
    13501 ttctgtcata ccgcctccag aaccattgac ggcggatctt gcgaatcagg ttttcaccca
    13561 tggcaacctt gatggagctt tactggcacc ttcattgatc gttgattgct acaacaataa
    13621 cgagtactgt gtcaatatga tccaacggct gaaatttctc tcatacgtcg gaggctctct
    13681 acccgcggaa gtcggcaact cactcacaac gagaaccaaa ttgatgactt tgatgggctc
    13741 ctgcgagacc gctctgcatc ctttggaaat caacgatgaa caaacagact gggagtatct
    13801 cacgattagc aaatttctcg gccactcttt ccataaagat agggacggtt attccgagct
    13861 aataataaga cgagctcccg agtacgaggt atttcaaggt gtcttctcta cgttccccga
    13921 gaaacaggaa tttgcctccg gcgatctttt cgagcaacac ccaagccgaa cagagtcttg
    13981 ggttttccga gcccgaacag acgacatcat tgcgttcact accgccgaga agctcaatcc
    14041 cgtcaccatg gagagtgtga tatccacaaa cccaaagatc aagtcggcac tcattggcgg
    14101 ccaagggaaa ttccaggcat ctctactact cgaaccctac gtctatccca aatctaaggt
    14161 agaggaggag cagtacatca aggacatctg gcctagtgtc ctgcgggcaa atcgtgactg
    14221 cccggcgcat ggacgcatca tgaaggggtt cgtgatgatc acagatccaa agaagccaat
    14281 tccaagagcc ggcaaaggga ctgtacaacg acacgcagca ctacagcttt atgccaaaga
    14341 gtttgaggcg ctatataaga agatgcagcc cagcgcgaac atcgaatcaa agctaccgga
    14401 acagcggtca caatcaataa tgcccgcaag agtgaacgga gttaatgata ttgatgccag
    14461 gatcgagaag gcccttgtaa agttgctccc agcagcaatg gaagaggcga tacgaaagac
    14521 gctgtcgcaa atgcttttgg gactcaatgg tcccttacct gtccagcaat ctgtggagaa
    14581 acctacgcct ctcttgacca acggccacac gtatagcact acaaatggca tcacaagtcc
    14641 cgtcaccaac ggagttagca aagaagtggg ggagccgact gccagcacac cgccaaaaga
    14701 tgtccgacaa ataatatatg acgaactggc cgagaacctg gacatgacag acgtgactga
    14761 tgatattgac ttgttcgatc atggactgga ttcgctccag gtacaaagct tggtgaccac
    14821 actgaacgct tacttgatcc gattaaagcc cggggtagag ctgcttcagg cgaagcaggt
    14881 gtacgataaa ccgaccgtga gagagatcat ggctatggtg gagtggtctg ttgtatgact
    14941 gacacagatg gtagtacgga atttgtgttt agttccacaa tgattaataa gtgatgcaat
    15001 tgtcataaga atatattcat taggggacag atgtctcaga gagtcttatt accaccatag
    15061 agaggttccc ctgtatcttg acaaaaagca aggtggcctt cggtcctcag gattgaagag
    15121 ccaatttttc attcgaacag taccggtatc attgaaatgg tacatatcga cgctaacctt
    15181 acagcagttt caagatggta ttctaaggct ttaaaatttc gtaccagcat atataataag
    15241 taggtgaccg ggcgcatggc tgacccacag agatggcgta tggtggtgca ggtggcagga
    15301 ttgcctagcg tgtttcggag gacccaggct acggtggata gtgcattcgt gccttgttgt
    15361 cacgcgtcga cgattgccat gacttggtct atgctgaatc cgtgtcagtt cgcggtctcc
    15421 gaagtttgcc tgatatcctg gtacctggga cttactagta gctgataaca gcctagagaa
    15481 gcccgccacc agcgaacgag taatccgcga taactggtaa gtttcaattt cccatttcac
    15541 agtctttgct ccggtctcca gtcacaatga gtggtctttc cagcagaggg cacctgaacc
    15601 tcaggcagat cattgcgaag atacccaaaa gcattctcga gccgactccg aatccagatg
    15661 caatcgattt gtcaatggca gagaaccacc tgatacgtga agagatacta aagatcgtca
    15721 agtcatcgat tgtgggggat ttgcactcca aagtaagata gatcgagtgc tgtcatgaat
    15781 cagtgatgta acggagaatt cccgtagcac ctcgactggc caaagggctt ctgcggagat
    15841 agcgatcttt taggccacct tacagacatt ttcaataaac gcttccatcc cttttccact
    15901 gtgaagcaag agcacgtaac agtcacatct ggcgcgtcag cttgtctgga cgcagtctta
    15961 tacactgtct gcgacccggg tgatggtgtc ctcgtcccta ctccatactg gggtgggtgt
    16021 ctttcttaat ttctcttctc ttgatattca gatatctctg cgtagttaga agtatcgaac
    16081 tggaggtagt gtagtcgtct agttacacta acgactcgac ttaggcggtt acgatgcctt
    16141 ccttaccagt cactccggcg taaaaccagt cagcgtcgac gtaccagatc ttgaagactc
    16201 gctggggcct gctctcatcg atgcacttga agacgcatat gagagttctg aatatcgtat
    16261 ccgagcgtta gtgttgtgca atccgcacaa cccgctgggg agatgttatt cgaaaaagat
    16321 gctcgaggac tgtgcaaggt tttgccaaag tcgcggtatc catctaatat cggatgaagt
    16381 gtttgcgttg agtagtttct gtcggaccaa tcactatgga aaggagacat attggtgtta
    16441 a
//
