LOCUS       scaffold_886           13807 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  .
ACCESSION   scaffold_886
VERSION     scaffold_886
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2025-04-15 23:24:59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13807
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13807
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[8266:13231]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8267..13231
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..13807
                     /SMILES="NC(Cc1ccccc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13807
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             1923..2456
                     /locus_tag="771523"
                     /transl_table=1
                     /translation="MTMELDTITTRALVTLVTFSPMPGGSLSSYEILEISTFQETIPRS
                     TSIPILTSTLSNGSPTVIGKTTIVSKNDGSSPSNPTLTPTSYSSISNPSDRASSVLTTS
                     SPTVPTADSPSTPRPTPNNLIAPGAAAGIGVGSAAAGAFIAVLIVWFIMCKARKSPKIP
                     NDDPGGSWLSSNTA"
     CDS             join(8267..10882,10937..13231)
                     /NRPS_PKS="Domain: PP-binding (12-67). E-value: 7.9e-07.
                     Score: 21.5. Matches aSDomain:
                     nrpspksdomains_771549_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (298-471). E-value:
                     5e-29. Score: 93.2. Matches aSDomain:
                     nrpspksdomains_771549_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (625-1009). E-value:
                     5.3e-80. Score: 260.8. Matches aSDomain:
                     nrpspksdomains_771549_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1110-1181). E-value: 5.5e-10.
                     Score: 31.2. Matches aSDomain: nrpspksdomains_771549_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1209-1466). E-value:
                     2.7e-28. Score: 90.7. Matches aSDomain:
                     nrpspksdomains_771549_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     248.5; E-value: 1.7e-75)"
                     /gene_kind="biosynthetic"
                     /locus_tag="771549"
                     /sec_met_domain="Condensation (E-value: 1.9e-28, bitscore:
                     86.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-81, bitscore:
                     260.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-10, bitscore:
                     28.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNMDFLVLKELCLTLQTEFSQLDLDASFIHHGGHSLTAAALVAAC
                     KAQGCELTTGKVLTSDSLRNLIHSAQPCAKPDSPDPVSKQVSSTYMGTPSRESSILSKL
                     SRNLRYQNDNMTPPEPDDFLSQKSLTLSPVTLNQIRSHALADSPSPSPERSSTPTSIEI
                     TSTLKRHSISSPQRLNASSLGSLSFPERHDDKLTEMQLSLIHGTLKTPGMNIITHCETY
                     YSHYIPTMKAAWKTVVEMEPIFQVLPLKKFLEEDRKVFDWRDATAVEEGDEKDGKGLCD
                     ENRIGSFFRVVPCTVAPKQLSRSKIIWIVHHSLIDGYSASLVFDKVRRVANGMSVQPGP
                     PFSRLAEDLRLFQQSHRDEGNAYWLKKLEQSNDAKTELLLPYVDEDAGQARNAEVVSDL
                     SSVVEKLRSAARDMNVTPAAFFNAAWALVLATYADSDMVAFGAVLSGRNLPLPNVAAVV
                     GPLVNTLPLYVNINRSLSVQEFVRSVFENLMELAEFQWTTPEHGFSRSFESALSMQFGP
                     PDPLQAAVMPIESPYTHQATEIPLSIAVEADGKLRFQYHRNRFSPKNIGKLVSCYEEAL
                     QLLLQAHATVDATMEGLLSCPSKAVLGRYGNCFSGLTTKTSVKRDLVTLFEATAQKFPD
                     DIAIERGDFSITYRDFDHVSSRLALRLTRLISTGDVVCVHSDRSVNWLIAIYSILKAGG
                     VYCSLDSALPPDLRNSMYSLADAKVYLTPSTSQLHLTPVDCELYMSVESALSEFDDPEV
                     GVLEHRQQPMPSSTAYLCFTSGSTGTPKGVLCTHEGLVAFQSDLEVRLFAQPGKKISQI
                     MSAAFDGSIHELFSALSYGATLVLQAGGDPFAHLHSVDSAILTPSIARVLNPEDFKRLS
                     TVYLVGEPVPQTVADKWSNHKQLYNMYGPTEGTCGATIKRLNPASPVTIGGPNPTTRIY
                     LLNSRKDMVLPGMIGEIYLAGVQIAKGYLNLPTETKDRFLPDTICRNGEQMYKTGDRGY
                     WNELGEIVCLGRNDRQIKLRGYRLDMNDLEIRIAKAMPTMEGIAISRRGDHLVAMVQPA
                     SMNTKDLLSRVAKVIPSYAIPQQITAVDRLPTTSAGKIDYAAVSRNSIGSPTCQKGAPR
                     TATERAVASAFNSVLNIGEGTRVTLGSSFVDLGGHSLQQLSLAKHLTRIFDLQIPLRLI
                     IERPALGELAKGIDDHKATNKPAMPPAHSLGQQQVSPIEKEWLQKYDVDAGSSCFNVAF
                     ISSFAEETVDRYVLAEAWNTVLARHKLLRSKYVPRRARPPLRSYASCAPQAQRVGNLDL
                     WTEVNRPFQVGRTNPARVTVTKDRLIVVLSHIVADYTTLAILLREASAVYNGQQLEPIS
                     RSYSDVDVWYRNVPPCYLDFWSTFLKDCPDSPPLLGRHQERSGCRGVSTVSSIDSHAFQ
                     EMLQYSHSAKVSLQQLVTGAVAICLQLDSPETDIVIGNPYMNRNSDEDLETVGLFLEPL
                     PVRIKYGLGPDETSDDIPETYMQAVQRSSQAALANAMPWHRLLDHLSIHPTYPDHPLLD
                     VMVSFHDYRQSLDLKMAGPDFESCFVWSEGSKFKLMCEFTVISDTKLLLRLEHDTECIS
                     AAEIQRIQTLIPQALSLLSQSIPHNELKRRLFAGEEPTCHQVMDTDQLFGTRLCDIE"
     aSDomain        8303..8467
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_771549_PP-binding.1"
                     /evalue="7.90E-07"
                     /label="771549_PP-binding.1"
                     /locus_tag="771549"
                     /protein_end="67"
                     /protein_start="12"
                     /score="21.5"
                     /tool="antismash"
                     /translation="LTLQTEFSQLDLDASFIHHGGHSLTAAALVAACKAQGCELTTGKV
                     LTSDSLRNLI"
     aSDomain        9161..9679
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_771549_Condensation_DCL.1"
                     /evalue="5.00E-29"
                     /label="771549_Condensation_DCL.1"
                     /locus_tag="771549"
                     /protein_end="471"
                     /protein_start="298"
                     /score="93.2"
                     /tool="antismash"
                     /translation="KQLSRSKIIWIVHHSLIDGYSASLVFDKVRRVANGMSVQPGPPFS
                     RLAEDLRLFQQSHRDEGNAYWLKKLEQSNDAKTELLLPYVDEDAGQARNAEVVSDLSSV
                     VEKLRSAARDMNVTPAAFFNAAWALVLATYADSDMVAFGAVLSGRNLPLPNVAAVVGPL
                     VNTLPLYVNI"
     aSModule        9161..11863
                     /complete
                     /domains="nrpspksdomains_771549_Condensation_DCL.1"
                     /domains="nrpspksdomains_771549_AMP-binding.1"
                     /domains="nrpspksdomains_771549_PCP.1"
                     /locus_tags="771549"
                     /monomer_pairings="Phe -> Phe"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9194..9247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0001"
                     /evalue="1.40E-04"
                     /label="C3_starter_134-155"
                     /locus_tag="771549"
                     /protein_end="327"
                     /protein_start="309"
                     /score="14.9"
                     /tool="antismash"
                     /translation="VHHSLIDGYSASLVFDKV"
     CDS_motif       9578..9667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0002"
                     /evalue="4.70E-10"
                     /label="C5_DCL_263-294"
                     /locus_tag="771549"
                     /protein_end="467"
                     /protein_start="437"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VAFGAVLSGRNLPLPNVAAVVGPLVNTLPL"
     aSDomain        join(10142..10882,10937..11347)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_771549_AMP-binding.1"
                     /evalue="5.30E-80"
                     /label="771549_AMP-binding.1"
                     /locus_tag="771549"
                     /protein_end="1009"
                     /protein_start="625"
                     /score="260.8"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FEATAQKFPDDIAIERGDFSITYRDFDHVSSRLALRLTRLISTGD
                     VVCVHSDRSVNWLIAIYSILKAGGVYCSLDSALPPDLRNSMYSLADAKVYLTPSTSQLH
                     LTPVDCELYMSVESALSEFDDPEVGVLEHRQQPMPSSTAYLCFTSGSTGTPKGVLCTHE
                     GLVAFQSDLEVRLFAQPGKKISQIMSAAFDGSIHELFSALSYGATLVLQAGGDPFAHLH
                     SVDSAILTPSIARVLNPEDFKRLSTVYLVGEPVPQTVADKWSNHKQLYNMYGPTEGTCG
                     ATIKRLNPASPVTIGGPNPTTRIYLLNSRKDMVLPGMIGEIYLAGVQIAKGYLNLPTET
                     KDRFLPDTICRNGEQMYKTGDRGYWNELGEIVCLGRNDRQIKLR"
     CDS_motif       10568..10627
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0003"
                     /evalue="7.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="771549"
                     /protein_end="787"
                     /protein_start="767"
                     /score="27.6"
                     /tool="antismash"
                     /translation="AYLCFTSGSTGTPKGVLCTH"
     CDS_motif       11141..11227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0004"
                     /evalue="6.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="771549"
                     /protein_end="969"
                     /protein_start="940"
                     /score="34.4"
                     /tool="antismash"
                     /translation="PGMIGEIYLAGVQIAKGYLNLPTETKDRF"
     CDS_motif       11312..11377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0005"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="771549"
                     /protein_end="1019"
                     /protein_start="997"
                     /score="21.0"
                     /tool="antismash"
                     /translation="CLGRNDRQIKLRGYRLDMNDLE"
     aSDomain        11651..11863
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_771549_PCP.1"
                     /evalue="5.50E-10"
                     /label="771549_PCP.1"
                     /locus_tag="771549"
                     /protein_end="1181"
                     /protein_start="1110"
                     /score="31.2"
                     /tool="antismash"
                     /translation="ERAVASAFNSVLNIGEGTRVTLGSSFVDLGGHSLQQLSLAKHLTR
                     IFDLQIPLRLIIERPALGELAKGIDD"
     aSDomain        11948..12718
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_771549_Condensation_LCL.1"
                     /evalue="2.70E-28"
                     /label="771549_Condensation_LCL.1"
                     /locus_tag="771549"
                     /protein_end="1466"
                     /protein_start="1209"
                     /score="90.7"
                     /tool="antismash"
                     /translation="QKYDVDAGSSCFNVAFISSFAEETVDRYVLAEAWNTVLARHKLLR
                     SKYVPRRARPPLRSYASCAPQAQRVGNLDLWTEVNRPFQVGRTNPARVTVTKDRLIVVL
                     SHIVADYTTLAILLREASAVYNGQQLEPISRSYSDVDVWYRNVPPCYLDFWSTFLKDCP
                     DSPPLLGRHQERSGCRGVSTVSSIDSHAFQEMLQYSHSAKVSLQQLVTGAVAICLQLDS
                     PETDIVIGNPYMNRNSDEDLETVGLFLEPLPVRIK"
     CDS_motif       12023..12085
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0006"
                     /evalue="5.60E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="771549"
                     /protein_end="1255"
                     /protein_start="1234"
                     /score="12.2"
                     /tool="antismash"
                     /translation="DRYVLAEAWNTVLARHKLLRS"
     CDS_motif       12263..12322
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0007"
                     /evalue="2.60E-03"
                     /label="C3_dual_135-156"
                     /locus_tag="771549"
                     /protein_end="1334"
                     /protein_start="1314"
                     /score="10.9"
                     /tool="antismash"
                     /translation="HIVADYTTLAILLREASAVY"
     CDS_motif       12623..12712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_771549_0008"
                     /evalue="4.50E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="771549"
                     /protein_end="1464"
                     /protein_start="1434"
                     /score="16.0"
                     /tool="antismash"
                     /translation="DIVIGNPYMNRNSDEDLETVGLFLEPLPVR"
ORIGIN
        1 aagctgctcc cgctgggctt ttgggcctgt tagggtatga atcaatcaat caatcaatca
       61 atcaatcaat cgcattagac gccaaaattt cttctcgccg gtggcttcca tgttgctggc
      121 gcgccaaaca tgaagtcaaa aatttcgcct aggtaatcat gccacgaggt tctcagctgc
      181 gctaccttta gctcaaactc aataagcaca acaagtaatt ccgtacctct tctcatcctc
      241 gtcgatagat aatgatgcgt taagatctgt ggcttgttat tctgtgaggg ggagtcttac
      301 tatggtcttt gttctgcttt gctgcagtgt cgtagaggaa gcctcataag gactgtgccg
      361 tctgggatgt ggttgtgatt ctcgggtaca cgatgatcgt cgggactttt tcctcgttta
      421 cgtgagccct tccggaccag tcctggtccc attggagggt ctggagccag ttggcggatt
      481 taggtaaaag ataatcctaa gtaatgggtc tgaagttagc tcttgaggct gtgcagcgag
      541 tcgagtccca gtcagccgat tttgccgggc ggaaaaaaga gagcgagtcc aaaatcaact
      601 ccaacactca gatctatctg gttttctccc atcttcggct ccagttcgat ctacagtgac
      661 tgacaatggc gcataggttc ttgaatgcac ggatatttat aaacttgtgt tttcgcaaga
      721 ataaccgatc ctatgaagtg tcataattct agctggttcc agccgcaggc ctcatgttgc
      781 acagcgtctg accccgccct cctccaattt ttgaccatct agtgccatcc ggttcttatc
      841 tacttcttat ggactttcat cgacgggcta cacatcaggc tctgaatctg atggctgatt
      901 gtatgtttca catcaactgc cgactgcgta ctttttacag ggtatttctg atccaaacat
      961 ggcggcaatg gtaagtccca ctcttttcct tccggcactc cagccactat caagcgtcta
     1021 aattaaactt gtgtttgagc cccacgacct gcgagtagat aagtctgtta ggatatttcc
     1081 tgcagtggct caccctcatc ctaatttcag ttttctaatt ccaatttatc ctttctaata
     1141 ttatttttta aaactactag atactgtaat acattcttga ggcatttgtg tgactgtcct
     1201 gtctctctga tgtctgtagc ccatttgctg gtgaaatgga ctgttttcag cttataggca
     1261 cctcgtctaa gtctccgggt ttggtttgag tatgtcgggg gggcacccat cataatatct
     1321 gcttctgagt acgggatagg tggtcgagac tttttttaaa ccccctaagc cgaaaaagtt
     1381 catttgatca gcaaacggaa aacgccactg catgatgttg aacggttgtg gggacaccct
     1441 tgccgatcga cttcctccac ccatcccatc ttccctgctc attaaattca gctggccatt
     1501 cagccgaatc atgacctagc cccagtcgtt caaggcccca tgttgagatg atccacgccc
     1561 ctttacggca atgtgacggt cgtgcgccaa atcattcccc gggaatcagc ctggatacct
     1621 gagcatgtac atgtccgata catgtgtaca accacaccat actcagcaat ggccagaacc
     1681 catcgtcatc agagacttat catggctatg ggcctttccc tcagctctgc cttatttagt
     1741 ttaaaataac atgcgttttc ccttgacttc ttgtttgaat gagctcaacc tcgtccttct
     1801 catttggcct tctctacaga gtaaactctt caacttctct tgctcggtga aagcgcacga
     1861 ctaatatcat aaagtcttgt gttctctttg cagagctttg atccattctc gctcattgaa
     1921 gcatgactat ggaacttgat actatcacca cgagggcttt agttacctta gtaaccttca
     1981 gtccgatgcc tggcggctca ctgtcctcct acgagatttt ggaaatatcg actttccagg
     2041 aaactattcc aaggtccacc tctataccga tacttacttc aacgctttcc aatggatcac
     2101 cgactgtgat cggcaaaacc accatagtat cgaaaaatga tggttcttct ccgtccaatc
     2161 cgacgctcac gccgacaagt tacagttcca tcagcaatcc atctgataga gcttcgtccg
     2221 tcctaaccac atcaagtccg actgttccca ccgcggactc acccagtacg ccaagaccca
     2281 cacccaataa tttgattgcg cccggtgctg cggctggtat tggagttgga agtgctgctg
     2341 ccggtgcatt catagctgtt ctcatcgtgt ggttcatcat gtgcaaagca cggaagagtc
     2401 cgaagatccc taacgacgat cctggaggat cctggttatc ctccaatacc gcatgatacg
     2461 ctatctaaga ggtgtggtag cacttggagt cgttattagc ccagccgttg ggcgatcaaa
     2521 aggttttatt tcgacaattt acacagacca tgtccgacgc cattatggaa tatgaaaagc
     2581 ggagggggag ggggaggata gggagaggaa gaagattgga actcattatt acagtttagg
     2641 acccactaca tatttcctcc tccaaaaatc tcctgatcga ttctccgaac caaaaaagtc
     2701 aacttacaaa ccttccatcc aatgctgctg ttctcttctc acctccatat ttcaaaaaca
     2761 tcaatatcgt cccctttttc ttggaaatga aagaaggttc tcgaaatggg attccgagaa
     2821 gcgcagaaga gttttttctt ccttctaatg ttcattgctt agagatacgg tttcgttcat
     2881 gacagttcca atatgaccgg tttccgaggc ctattccata ctatagtggc ggccggccat
     2941 cgggcgggtt gttcataaag gaaagtgcgt gaccgaaggg gtgcataaga ggaaaacggt
     3001 gaccaaccaa ataccaaaag gaaaaaccct cattttcgct gttttgagaa tggttgtatt
     3061 acgatctaga tttctcaata tatattgcaa gccggtcaag cctaagattc actgatcgct
     3121 tctcgtcgga atcaaacagt cagctctgcg ttctttcatc gagttctttc gagtaagaaa
     3181 ctccacgata acaccagttg gaacactccc ccaaaaaggt aagtaagaga ggtagtaggt
     3241 acggctgtac aacgagccga ttcactaatt acaatcgtgc ctagtttacc aactgataag
     3301 tcgatatcgg ccactgtgca taaccaaaaa aggggcgata aagccgtgta cggagaaaag
     3361 aaaaccttgg accgggctga ccttaatgaa atagttatcg atctacgtct ttcccccgcc
     3421 caactgttag attcggacgc agctttctcc cggagccttg ctttccaacc ccttgatcaa
     3481 aatccgaccc cttagctctg tcttcgttca tgggattgat tggccttggt tgtcgctcag
     3541 aaatcagtgg ctagattcct tttcccgttg tgtttcggcc gctggagaat taagaccgtc
     3601 cctccttttt gggaatggta cgcgctgatt taggctgcgc tactgctcct tcgattctat
     3661 ccccactctt gctatcttat tgcttccctg cgactttcta ctgaagataa agatgccttc
     3721 tgaagctttt acagctttgt caagtgaggg ttttttgatt ggctgtacct tgcccagctt
     3781 cgatttcaaa tgatccccga acgattaatc ggaggttgaa atcattctct ctcttttcct
     3841 tcttgctcgg cgacggtgtt gaattaacgt gttttctctt ttcaccgact tggatcgtct
     3901 catcggggac cttcttattc ccctgcacaa cgcactttta accaggaatt cggagattgt
     3961 gttatctact gtattttcat tatcgagctt gccttccaat cccgcatttg tgccttgtga
     4021 gagagtgaag ctggcctcct ccggagcttg gtcgcattat ttggcggaag atcatgggga
     4081 atggctagct gcctgggatt gaggtctgcg aattaaaata tttatatgga gtagtctcga
     4141 ggagctatcc tctttgttca ttcagacaga catttgttcc attcaagtat cgaagcaatc
     4201 tactactttc ccccccctac aaacaggtct atattaagct gctgtatcga agtatccagt
     4261 attttgagta tagcattacg tcctcacagt atttgtgttg gcaatttgtg gattttttgg
     4321 tatttctgtc ctcgattttg caagcaggag aataaaacct acgtataaac cccatactac
     4381 cccttttcag cgcagtgcgg gcaatttgca gttgaaaagg tgcaaaaaga cttgccgcaa
     4441 agttaaggaa acatctctgg accacagcag tctgccatcg tcaccccggg atcaacgcaa
     4501 gcaagcatgg gcacccgtcc ctcaccaaaa aaaaacgccg acggctgact aagagctaca
     4561 ctgtacttta tcaaattttt caactgggca acactgaaac cagcttaata tccgagaggc
     4621 gcttgtgact tcaatatctg cacttttcga gttgacagtg atgctgtttt caccccttat
     4681 actgcttctt catcacaatt cacaaacccc tttgtcaagt actgcattca gtgcttgctt
     4741 actctgacat aaaatagagt agcttcttag cttatgcttt taccgctggc cctcaaactt
     4801 ggctgaatac ctaaccacct cacggaaaag catgtctaat tatcgaagat aggagacgtt
     4861 aacgtcttga agaaataaaa aaaatgggtt tactagacca agttcatgca ggttgctcaa
     4921 tgtataaatt atcaggagtc catatgcccc tacatatctt ctacccacat gtgcctgccg
     4981 cctttgctat ctcggtcgct tttgatcctg ttctaccttg ccgctgcccc cttcttaacc
     5041 ccatatctcg ttcccttcaa ctgttttgtt acctgttcct attgcccctg gctccatgtt
     5101 ttaatcttgt acaaattgca cccgtatttt tgcccttctg cttcttctca tcctctggct
     5161 ctccctcgtc ctcctacacc ttctcctccc gcgcggcctc agcccccacc cctttttgtc
     5221 ttctttcttt ttctttttct tgccactcgc tctctctctc ggagctgtag cctcgcttgc
     5281 cgatgcatca acgcatctct tcgtgccaat gccttttgtc ttgccgatgc ttctcttctc
     5341 gccaatgatt gttttcttgt tgccaattct tgctatacct acttttctca tgcccgattc
     5401 tcatcacact gtggcaggga ggaatggggc ggagcggatg tggcctgtcc gtggctgctt
     5461 tttccccccc tttttgtgtt agcttgcttg ttctccgcct tcactccctt ttctaaaacg
     5521 gtctatacaa gaaggatgga agacttgcag ggtcggaagt tttcagggtt tctcttggag
     5581 tcagttcttt aattttctcc tatgagtcag cgatactatt gcccctcagg ggtataagag
     5641 agcaataata atgtgtgcta ggtggatcag cgaacacgac ttcctcgaac cagtaaatca
     5701 cacagagctc atttaattcc ctcttcttta cctcttccaa ttacatttgc tcctgcagag
     5761 caccataagt tttccccgtt cgactcccac taagtattcc aaacccccta ctcccttttc
     5821 attctgaccc cttttcctcc tacccttctt catccctcct tactatcgaa accatttcga
     5881 ccacttgcct gctctgcttc taggaatctc ggtatttctc aacagtagat tctagggtaa
     5941 ataatcaatg attatcccct tgatttgagc atgactcacc aaaaacgaat atcctacaga
     6001 gtgcaatacc atctttacca atgacaaatg aaaatcaaaa taccctcgcc taatatcctc
     6061 agtggctttt tcagaagtgt cacgctgctg ccgccgctgg aaacgaccct cgacgatgcc
     6121 ctcggtcact tagccagctc tgacaattct ttctctaccc aaaattttga aatcgactgt
     6181 ttcaaacttg acaaagggct tagcagtttc gattatatta agattgtagt tgctgttaaa
     6241 tctggtacca atagcctaca aatactactt tgggggtgac ttcgctgttc tcgatgtact
     6301 ccaagctgac ctggtatttc tcacctgctt atatcaaagg ttccaacctc accctacgcg
     6361 catcatacag cgattcggag gatccaatga tgatgattta ttacactatt cttagctaaa
     6421 tagctcattt aggggttcta taattccgtg taggaaaata gcgtccgtcc gctggaaaaa
     6481 cctaagctga tctcttatcc ctgtgttttt gatatagtcg actccacgtc acgcaactgt
     6541 gagagctgtg tgcttcgcac gtgtttcttc tgacgacttg gcttcttttt ctctcggtcg
     6601 caaaatcctg ccaaaccctt actatcgatc taagtcctcc tcgtcggcac cgtcgtcgcc
     6661 gtcgtcatcc tcgtctcttg ccctgccctc cacacgatca acctgctctt tcgccagcga
     6721 gaattgcaac aaaagacctt cgctcatgat ccatcgagcc actgcacgaa ggcctgatga
     6781 tgactaatca tgatatgaat cgaccggtcg tcagaaaaaa gttgggggtg gtgcttaggg
     6841 tatgagcaac cttggtcgaa aagccgtaat acagttcttc agaacgattc cgaggaattt
     6901 tcttttttgc gcaaagatga tgtttgatat ctaactatag attgacatat tcaagtggta
     6961 cagaaatcgt aggtaggatg tgagaatgtc aggactagga agtttgcggc gtgcgagaat
     7021 ttgatcctga gtcctaaatc gtgtcggtgc taatgactac gcagcgtaat cgaaaaacag
     7081 accagagtgg tttcttcggc gacttcccaa ggaatatccc gtccactttg aagaacttta
     7141 tggcgtgagt tcaatcctac aggagtggtg gatgcggtca tcgttgcaca ataaaaaggt
     7201 aacggaccgc ttgacgcgat gctgaaacat gatctgacta gaagagagga agtaagtcag
     7261 gtgacttgag cgtggcaaat taagtaccta tgtaacaccc tctaagtaca gtaaggtacg
     7321 gtaactttca ttagctccta catgtttcaa acaaattcgg aatcccctcg catcccctcg
     7381 ccctcgtttt cgccctctcc tatcctctcc tctcctctct tctacacttc accaattaac
     7441 ccatagtaca tactcccttc accatgctaa catctctatt gaccgactcg gttctgtttg
     7501 aaatagagag acaccccatt tggctgcagc tccgactcga gaacagagag tacggagcgt
     7561 acggagtaca aggtacggaa atacggagag cagggaatct ggctcgcgct gcataggcgt
     7621 tcgataccga tttctcagtc agtatgtaag ccattctttc acgccggcat gtaccatctt
     7681 ctcctcgaga ggtccgtaga tagtgtttcg gaaatatacc tctaatgtct gcatagctcc
     7741 atggctcatc aattaggatt tgggcttgct tcggcatttt cagattggcc tatcattgcc
     7801 tcagtagtcg agcctctgat gttgtattcc tttacactgg tcaccatcta gagcaatttt
     7861 actttaacat gttttaccac ggcccggctg tgtgcaccag cactgttctg tacggatacc
     7921 gtcatctcac cgggcaccgg cattggtttc caaaatgttt cgacagagag aagacactcg
     7981 ggcatcagtt tggcatagca ctgatgatct ccatggcctt taggacaaga ttatcacaat
     8041 tctattttca ccaacgccct tggtgatgtt cactgtcact ctccgtgcac ttctatgacg
     8101 tctttgtcga tgtaatagct ctcacttcag attctgattg tataaaagag ctcggcgatg
     8161 tcgaacttct tttttttctt ttttcttttt ttacaaaaag gtaacgatca ggatttcaca
     8221 caattgaatt ttgggcttcg atatttttga tcataccatt cttttcatga atatggactt
     8281 cttagtctta aaggaactgt gcctaaccct ccagaccgaa ttctcccaac tcgatctcga
     8341 cgctagtttc atccatcatg gtggtcattc tctcaccgcg gctgctctcg tggccgcatg
     8401 caaagcgcaa ggctgtgaat tgacaactgg aaaagtccta acaagtgact cactgcggaa
     8461 cctcattcac tccgcacagc catgcgcgaa gcctgattct ccagacccgg tgtccaagca
     8521 agtctctagc acctacatgg gaacgccctc gagagaatct tcaatactct caaagctatc
     8581 tcgaaacttg cgctaccaaa acgataacat gacccccccg gaacccgatg actttcttag
     8641 tcaaaaatca ctcactctta gtccagtaac cctcaatcaa atacggagcc atgcgctagc
     8701 ggattctccc tccccatcac ccgaaaggtc gtcgactcct acatccattg agatcacctc
     8761 gacccttaag aggcattcca tttcgagccc acagcgtctt aatgcatcct ccttgggatc
     8821 tctttcattc ccggaacgtc atgacgataa gctcacagag atgcaactgt ctctgattca
     8881 tggtactctt aaaaccccag gaatgaacat aatcacccac tgcgaaacat actattctca
     8941 ttatattccc actatgaaag cggcatggaa gaccgtcgtc gagatggaac cgatatttca
     9001 agtcttgcct ttgaagaagt ttctcgagga agataggaag gtattcgatt ggcgtgacgc
     9061 aactgcagta gaggagggag acgaaaaaga cggaaagggg ctatgcgatg agaatcgtat
     9121 cggatcgttc ttccgggttg ttccttgtac agtggcgccg aagcaactga gccggtcgaa
     9181 aattatttgg atagttcatc attcccttat tgatggctac tccgcttctc ttgtgtttga
     9241 taaagttcga agagtggcca atggaatgag cgtgcagccc ggccccccat tttcccggct
     9301 ggccgaggac ctcagattat ttcaacaatc acatcgcgac gaagggaatg cttattggct
     9361 gaaaaagctt gaacaaagca acgatgccaa gactgagcta ctgctacctt acgtggacga
     9421 agatgctggc caagcacgaa acgctgaggt agtcagcgat cttagctccg tcgttgagaa
     9481 gctgagatcg gcggctcgag atatgaacgt tacgccagca gctttcttta atgctgcatg
     9541 ggctttagtt ttggcaacat atgctgattc cgacatggtt gcttttggcg ctgttctctc
     9601 gggacgaaat ttaccgttgc cgaacgtggc tgctgttgtg ggaccgcttg taaacactct
     9661 ccctttatac gtcaacatca accgaagcct ctctgtacaa gaatttgttc gctcggtctt
     9721 tgaaaacctg atggagctag cagaatttca gtggacgacg cccgagcatg gattttctcg
     9781 cagtttcgag tctgccttgt ccatgcaatt cggaccgcca gaccccctac aggccgcagt
     9841 aatgccgatt gaaagccctt acacccacca ggctacggaa atcccactca gcatcgcggt
     9901 tgaagcagat ggaaagcttc gatttcaata tcatcgcaat cgattcagcc cgaagaacat
     9961 tggtaaattg gtctcatgtt atgaggaggc gctgcagttg ctgctgcagg cacatgcaac
    10021 cgtcgatgcg acaatggagg gactgctctc atgtccctcc aaagcagtat tggggagata
    10081 cggaaactgt ttctctgggt tgacaaccaa aacgtctgtc aaacgtgact tggtgactct
    10141 ttttgaagcg acggcgcaga aatttccaga tgacattgcc attgaaagag gagacttttc
    10201 catcacttat cgagattttg accacgtttc tagtcggtta gctttgcgac tcacgcgcct
    10261 catctctaca ggcgatgtcg tttgtgttca ttcggatcga tcagttaatt ggcttattgc
    10321 catctacagc attctgaaag ctggaggagt atactgttcg ttggacagtg ccttacctcc
    10381 tgacctccga aattcaatgt attcacttgc tgatgcaaag gtctatttga ccccttcaac
    10441 atcgcaactg cacttaaccc cagttgattg tgaattatac atgtcggttg aaagtgccct
    10501 aagcgagttc gatgacccag aagtaggagt cttggagcac cgacagcagc caatgccatc
    10561 atcaacggcc tacttatgct ttacttctgg ttcgactggc acgccgaaag gcgttctctg
    10621 tacccacgag ggtcttgttg cttttcagag cgacctggaa gttcgactgt tcgctcaacc
    10681 cggaaagaaa atctcccaga ttatgtcagc tgcctttgac gggagcatcc atgagctatt
    10741 ctccgcactt agttatggtg ctactctggt tttacaagca ggtggagacc cgtttgcaca
    10801 ccttcattca gttgactcag ccattctgac tccttcaatc gctcgtgttt taaacccgga
    10861 agactttaag cgtctaagca cggtgggtgt agaagcattt tttccaaaag ctacttagcg
    10921 ctaacacacg aagtaggtct acttggtggg cgagcctgtg ccacaaactg tcgctgataa
    10981 gtggagcaac cacaagcagt tgtacaacat gtacggacca actgaaggaa cctgtggagc
    11041 tacgattaag cgcctaaacc ctgcaagtcc ggtcacaatt ggaggcccga atcctaccac
    11101 ccgaatatac ttactaaatt ctcgcaaaga catggtgctg ccaggcatga ttggagaaat
    11161 ctacttagct ggagttcaaa ttgccaaagg ctatctcaac ctaccgactg agacaaagga
    11221 ccgattctta ccggacacaa tatgccgcaa tggggagcag atgtacaaga cgggagacag
    11281 aggctactgg aatgagctgg gtgaaatcgt ctgtcttggt cgtaatgatc gacagatcaa
    11341 gctccgcggc tataggttgg atatgaatga tcttgaaatt cgcattgcca aggctatgcc
    11401 cacgatggaa gggattgcaa tctctcgccg aggagaccac ctagtcgcca tggttcaacc
    11461 tgcgtcgatg aacaccaaag atcttctttc gagggtagca aaagttatac cctcgtatgc
    11521 tattccacag cagataaccg cagtggaccg actacccacc acctcggcag gtaagataga
    11581 ttatgctgca gtgagccgca atagcattgg gagtccgact tgtcaaaaag gcgctcccag
    11641 aacagcaacc gagagagcag tggctagtgc attcaattct gttttaaata taggtgaggg
    11701 gaccagagta actttgggat ccagctttgt cgatcttggc gggcattctc tacaacaact
    11761 ttccctagcc aagcatttga caagaatctt tgatcttcag ataccattgc ggttgataat
    11821 tgaacgtccg gcgctcggag agttggcaaa aggcatcgac gatcataagg ccacaaacaa
    11881 gcctgcaatg ccacctgccc actccctggg ccaacagcag gtttcgccaa tcgagaagga
    11941 atggctgcag aagtatgatg ttgatgcagg ttcttcctgc ttcaacgtcg ccttcatctc
    12001 cagttttgcc gaagagaccg tcgaccgcta cgtgctagca gaggcttgga acacagtatt
    12061 ggcaaggcat aagctgctgc gcagcaaata tgttcctcgt cgtgcaagac cccctttacg
    12121 atcttatgcg agttgcgcgc ctcaggcaca acgagtagga aatctggatt tatggactga
    12181 agtgaaccgc ccttttcagg ttggccgcac gaatcctgca cgagtaactg tcacgaaaga
    12241 cagattgatc gtcgtcctga gtcacatcgt ggcagattac acaaccttgg ctatcctcct
    12301 gcgggaagct tcggcggtct ataatgggca acagcttgaa ccaatttcgc gaagctattc
    12361 cgacgtcgac gtctggtatc gcaacgtgcc cccgtgctat ttggattttt ggtccacttt
    12421 tctcaaagac tgtcccgaca gccccccgct gctagggagg caccaagagc gcagtggatg
    12481 tcgtggtgta tcgacggtgt cctcgattga tagtcacgct tttcaggaaa tgttgcaata
    12541 ctcccactcc gccaaggttt cccttcagca gctcgtcaca ggagctgtgg caatatgtct
    12601 gcagctggac tcaccggaga ctgatattgt cattggaaac ccgtatatga atcgcaattc
    12661 ggacgaagat cttgagacgg taggcttgtt tctagagcca cttccagtaa ggatcaagta
    12721 tggccttgga cccgacgaaa catccgacga cataccggag acgtatatgc aagccgtgca
    12781 gagatccagc caagcagctc ttgcgaacgc gatgccttgg caccggcttc tagaccatct
    12841 ctccatacat ccgacctatc ccgaccatcc acttctggac gtcatggtca gcttccacga
    12901 ttaccgccaa tcgctcgacc tgaaaatggc ggggcccgac ttcgagagct gtttcgtctg
    12961 gtcggagggg tccaaattca agctcatgtg cgagttcacc gttatctccg acaccaagct
    13021 cctgctgcgg ctcgaacacg acaccgaatg catctcagcc gccgagatcc agcgcatcca
    13081 aaccttaatc ccgcaagccc tgtcgcttct tagtcagagc attccgcaca acgaactcaa
    13141 acggcggctt ttcgccggcg aggaaccgac gtgccaccag gtcatggata ccgaccagct
    13201 atttggtacg agactctgcg atattgaata gaggtccgac aaaagaacaa gaggaggggg
    13261 gctgggttca tctcaagatt agatggaaga gaaggcattt gtatttcccc caacgcggca
    13321 gcacctaaac tcatcattta aaagaaaaat ctttggattt agagcttgcg aaaaagattt
    13381 ttttaccccc ctctgccctt agacataaca tggaggatta gaaaagccag ctcataaaat
    13441 aaatagagaa agattagaag aagggcaaaa gaaaacagaa acacccccaa tctagtagca
    13501 ccctcttgat acaaaacacc cccgtgaacc acgtatttaa cacaattccc tcaattcaac
    13561 tttccccccc cccttctctt ttcaaaaaat ctcgtccctc tctaactctc tcacaaaaga
    13621 aaacccccaa aacatccttc gctccccccg ctttccccag ggctggtcta taggattatt
    13681 tccccccccc tttcccgggt ttcttattcc ctaaaaaccc acccccaatc ctccccgggt
    13741 ttcaagtttt gtcctaacaa caaacccccc gccgttcttc cccccgccgt ttttccccct
    13801 ttcgtta
//
