Home • Aspergillus fumigatus A1163
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Conidia: phialoconidia of Aspergillus fumigatus. Picture Source

This genome was sequenced by J. Craig Venter Institute.

The genome sequence and gene predictions of Aspergillus fumigatus A1163 were not determined by the JGI, but were downloaded from ENSEMBL and have been published (Natalie D. Fedorova (2008), William C. Nierman (2005), Catherine M. Ronning (2005)). Please note that this copy of the genome is not maintained by the author and is therefore not automatically updated.

Aspergillus fumigatus is exceptional among microorganisms in being both a primary and opportunistic pathogen as well as a major allergen. Its conidia production is prolific, and so human respiratory tract exposure is almost constant. A. fumigatus is isolated from human habitats and vegetable compost heaps. In immunocompromised individuals, the incidence of invasive infection can be as high as 50% and the mortality rate is often about 50%. The interaction of A. fumigatus and other airborne fungi with the immune system is increasingly linked to severe asthma and sinusitis. Although the burden of invasive disease caused by A. fumigatus is substantial, the basic biology of the organism is mostly obscure.

 

Genome Reference(s)