Home • Fusarium proliferatum 312A_c15_2 v1.0
Photo of Fusarium proliferatum 312A_c15_2 v1.0
Fusarium proliferatum 312A_c15_2 growing in the lab.
Image Credit: Kathryn Bushley

Within the framework of JGI Community Sequencing Project “Defensive Mutualism of Fungal Root Endophytes of Soybean”, we are investigating the potential role of fungal endophytes isolated from soybean roots in protecting against two root pathogens: 1) the root rot fungus causing Soybean Sudden Death Syndrome (Fusarium virguliforme) and 2) the soybean cyst nematode (Heterodera glycines). These fungi were screened for either anti-fungal or anti-nematode activity in-vitro and genome, transcriptome, and metabolome sequencing will address possible mechanisms of antagonism against these pathogens.

Fusarium proliferatum is a species within Fusarium, a large and diverse genus of filamentous fungi with diverse lifestyles. Some are pathogens or endophytes of plants, while others are opportunistic human pathogens. Some Fusarium species are known for producing mycotoxins that can be harmful to humans and animals [1]. Fusarium proliferatum has a broad host range, causing root rot, seedling blight, and vascular wilts in many crop species. Additionally, this fungus is known to produce mycotoxins, including fumonisins [2], which can contaminate crops such as corn and other grains and cause negative health impacts in humans and livestock [3, 4]. The 312A_c15_2 strain was isolated from soybean roots and showed antagonism against soybean cyst nematode juvenile 2 worms.

Researchers who wish to publish analyses using data from unpublished CSP genomes are respectfully required to contact the PI (Dr. Kathryn Bushley) and JGI to avoid potential conflicts on data use and coordinate other publications with the CSP master paper(s).


  1. Nikitin, D.A., et al., Diversity, Ecological Characteristics and Identification of Some Problematic Phytopathogenic Fusarium in Soil: A Review. Diversity-Basel, 2023. 15(1): p. 18.
  2. Bacon, C.W. and P.E. Nelson, Fumonisin proudction in corn by toxigenic strains of Fusarium moniliforme and Fusarium proliferatum. Journal of Food Protection, 1994. 57(6): p. 514-521.
  3. Ekwomadu, T.I. and M. Mwanza, Fusarium Fungi Pathogens, Identification, Adverse Effects, Disease Management, and Global Food Security: A Review of the Latest Research. Agriculture-Basel, 2023. 13(9): p. 20.
  4. Glenn, A.E., Mycotoxigenic Fusarium species in animal feed. Animal Feed Science and Technology, 2007. 137(3-4): p. 213-240.