Home • Fusarium oxysporum f. sp. lycopersici 4287 v2
Fusarium wilt of tomato caused by Fusarium oxysporum f.sp. lycopersici.
Fusarium wilt of tomato caused by Fusarium oxysporum f.sp. lycopersici.
Image Credit: David B. Langston, University of Georgia, Bugwood.org

The genome of Fusarium oxysporum f. sp. lycopersici strain 4287 (race 2, VCG 0030) was sequenced by the Broad Institute and the text below is copied from there. In order to allow comparative analyses with other fungi, a copy of this genome was imported into MycoCosm.

Fungi of the Fusarium oxysporum species complex (FOSC) are ubiquitous soil and plant inhabiting microbes. As plant pathogens, FOSC strains can cause wilt and root rot diseases on over 120 plant species (Michielse and Rep, 2009). Many FOSC strains can infect plant roots without apparent effect or can even protect plants from subsequent infection (Alabouvette et al., 2009). FOSC isolates also have been identified as human pathogens causing localized or disseminated infections that may become life-threatening in neutropenic individuals (O'Donnell et al., 2004).

The first genome made available in 2007 was from a tomato wilt strain FOL 4287 (NRRL 34936) which was used for comparative analysis with the genomes of F. graminearum and F. verticillioides. Results of this comparison led to the discovery of mobile supernumerary chromosomes in this strain of F. oxysporum f. sp. lycopersici (race 2 - VCG 0030) containing genes required for host specific infection and disease (Ma et al., 2010).

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