Home • Hypoxylon investiens CIRM-BRFM 1445 v1.0
Photo credit: Jana M. U'Ren. Grown on 2% Malt Extract Agar.
Photo credit: Jana M. U'Ren. Grown on 2% Malt Extract Agar.

Hypoxylon investiens CIRM-BRFM 1445 was sequenced as a part of the project "Comparative and population genomics of Xylariaceae: exploring the roles of endophytic fungi in lignocellulose degradation, nutrient cycling, and secondary metabolite production" (CSP 503506; PI. J.M. U'Ren). Xylariaceae comprise one of the largest and most diverse families of filamentous Ascomycota, with important ecological roles as saprotrophs of wood, litter, soil, and dung, as plant pathogens in agricultural and natural systems, and as asymptomatic endophytes in the photosynthetic tissues of all lineages of land plants and lichens (U'Ren et al. 2016 and references therein). In addition to their impact on plant health, xylariaceous endophytes are increasingly being recognized as a major source of novel metabolic products for use in medicine, agriculture, and industrial biofuel applications (e.g., Wu et al., 2017).

Researchers who wish to publish analyses using data from unpublished CSP genomes are respectfully required to contact the PI and JGI to avoid potential conflicts on data use and coordinate other publications with the CSP master paper(s).

References:

  1. U'Ren, J.M., J. Miadlikowska, N.B. Zimmerman, F. Lutzoni, J.E. Stajich, A.E. Arnold. 2016. Contributions of North American endophytes to the phylogeny, ecology, and taxonomy of Xylariaceae (Sordariomycetes, Ascomycota). Mol Phylogen Evol 98, 210-232.
  2. Wu, W., R.W. Davis, M.B. Tran-Gyamfi, A. Kuo, K. LaButti, S. Mihalcheva, H. Hundley, M. Chovatia, E. Lindquist, K. Berry, I.V. Grigoriev, B. Henrissat, J.M. Gladden. 2017. Characterization of four endophytic fungi as potential consolidated biosprocessing hosts for conversion of lignocellulose into advanced biofuels. Bioenergy Biofuels 101, 2603-2618.