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Home • Rhizomucor pusillus CBS 18367
Photo of Rhizomucor pusillus CBS 18367
Photo credit: Genevieve Quenneville, Sandrine Marqueteau and Marie-Claude Moisan

The genome sequence and gene prediction of Rhizomucor pusillus CBS 18367 have not been determined by the Joint Genome Institute (JGI), but were downloaded from CSFG on July 31, 2022. In order to allow comparative analyses with other fungal genomes sequenced by the JGI, a copy of this genome is incorporated into Mycocosm. Please note that this copy of the genome is not automatically updated. JGI tools were used to automatically annotate predicted proteins.

Rhizomucor pusillus is a thermophilic fungus from the order Mucorales. Its growth optimum is 45 ºC (1) and it is one of the agents causing zygomycosis in immunocompromised patients (2). In general R. pusillus strains are unable to degrade complex cell wall polysaccharides, data supported by the lack of enzymes encoded in the genome. However, the identification of endoglucanase and xylanase activity in culture and enzymes encoded in the genome indicates that other strains of R. pusillus are able to degrade oligo- and polysaccharides to a certain extent (3,4). The genome of R. pusillus will provide insight into the evolution of themophily and pathogenicity in fungi.

Note: If you intend to publish any articles including Rhizomucor pusillus CBS 18367 genomic data, please contact Adrian Tsang for permission prior to publication: [email protected]

 

Reference:

1. Morgenstern I, Powlowski J, Ishmael N, Darmond C, Marqueteau S, Moisan MC, Quenneville G, Tsang A. A molecular phylogeny of thermophilic fungi. Fungal Biol. 2012 Apr;116(4):489-502.

2. Masatomo Kimura, Shun-Ichi Udagawa, Koichi Makimura, Kazuo Satoh, Noritsuna Toyazaki, Hiroyuki Ito, Isolation and identification of Rhizomucor pusillus from pleural zygomycosis in an immunocompetent patient, Medical Mycology, Volume 47, Issue 8, December 2009, Pages 869–873,

3. Hüttner S, Granchi Z, Nguyen TT, van Pelt S, Larsbrink J, Thanh VN, Olsson L. Genome sequence of Rhizomucor pusillus FCH 5.7, a thermophilic zygomycete involved in plant biomass degradation harbouring putative GH9 endoglucanases. Biotechnol Rep (Amst). 2018 Aug 31;20:e00279.

4. Thanh VN, Thuy NT, Huong HTT, Hien DD, Hang DTM, Anh DTK, Hüttner S, Larsbrink J, Olsson L. Surveying of acid-tolerant thermophilic lignocellulolytic fungi in Vietnam reveals surprisingly high genetic diversity. Sci Rep. 2019 Mar 6;9(1):3674.