Sarocladium kiliense UNK
This genome represents one of two metagenome-extracted genomes that were recovered from contaminated DNA and RNA samples, initially part of the Aspergillus whole-genus sequencing project.
The top two metagenome bins for this sample matched Sarocladium kiliense UNK and Aspergillus bicolor CBS425.77. Binned DNA reads were assembled separately, and a shared transcriptome library was assembled by Trinity. Subsequently, the JGI Annotation Pipeline was used to produce structural and functional annotations.
Sarocladium kiliense, formerly known as Acremonium kiliense, is a ubiquitous soil saprobe that is also known to be an opportunistic human pathogen (1). Sarocladium is a member of the order Hypocreales and its genome sequence will enrich our understanding of evolution in the Sordariomycetes. (2)
References
- Fernández-Silva F, Capilla J, Mayayo E, Sutton D, Guarro J. In vitro evaluation of antifungal drug combinations against Sarocladium (Acremonium) kiliense, an opportunistic emergent fungus resistant to antifungal therapies. Antimicrob Agents Chemother. 2014;58(2):1259-60. doi: 10.1128/AAC.02131-13. Epub 2013 Nov 18.
- Giraldo A, Gené J, Sutton DA, Madrid H, de Hoog GS, Cano J, Decock C, Crous PW, Guarro J. Phylogeny of Sarocladium (Hypocreales). Persoonia. 2015 Jun;34:10-24. doi: 10.3767/003158515X685364. Epub 2014 Oct 30.