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Home • Penicillium chrysogenum Wisconsin 54-1255
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Penicillium chrysogenum (image source: wikipedia)

The genome sequence and gene predictions of Penicillium chrysogenum were not determined by the JGI, but were downloaded from NCBI genome and have been published (van den Berg MA et al., 2008). Please note that this copy of the genome is not maintained by the author and is therefore not automatically updated.

This genome was sequenced by van den Berg MA et al. in DSM Anti Infectives. Penicillium chrysogenum, also known as Penicillium notatum, is a filamentous asexual fungus with a relatively small genome. It has been used for over 60 years for the industrial production of penicillin, an antibiotic commonly used to treat bacterial infections. It is currently the primary commercial source of penicillinV and penicillinG. Strain improvement has resulted in increased productivity over the original isolates, mainly due to the amplification of a large genomic fragment containing the penicillin biosynthesis gene cluster. The biosynthesis of penicillin and the genes involved have been characterized in detail. P. chrysogenum has a haploid genome size of 34.1 Mb and distributed over four chromosomes.

 

Genome Reference(s)